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https://www.readbyqxmd.com/read/28434067/sediment-metal-contamination-in-the-kafue-river-of-zambia-and-ecological-risk-assessment
#1
Ethel M'kandawire, Kennedy Choongo, John Yabe, Maxwell Mwase, Ngonda Saasa, Shouta M M Nakayama, Nesta Bortey-Sam, Claudia A Blindauer
Zambia's Kafue River receives wastes from various sources, resulting in metal pollution. This study determined the degree of contamination of 13 metals (Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Cd, Hg and Pb) in Kafue River sediment and the associated ecological risks at six sites in three different seasons. The level of contamination for most metals showed significant site and seasonal differences. The contamination factor and pollution load index indicated that concentrations of most metals particularly copper (Cu), cobalt (Co), manganese (Mn) and arsenic (As) were very high at sites within the Copperbelt mining area...
April 22, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28433864/arsenic-metabolism-and-cancer-risk-a-meta-analysis
#2
REVIEW
Brenda Gamboa-Loira, Mariano E Cebrián, Francisco Franco-Marina, Lizbeth López-Carrillo
OBJECTIVE: To describe the studies that have reported association measures between risk of cancer and the percentage distribution of urinary inorganic arsenic (iAs) metabolites by anatomical site, in non-ecological epidemiological studies. METHODS: Studies were identified in the PubMed database in the period from 1990 to 2015. Inclusion criteria were: non-ecological epidemiological study, with histologically confirmed cancer cases, reporting the percentage distribution of inorganic arsenic (iAs), monomethylated (MMA) and dimethylated (DMA) metabolites, as well as association measures with confidence intervals (CI) between cancer and %iAs and/or %MMA and/or %DMA...
April 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28433805/chronic-early-childhood-exposure-to-arsenic-is-associated-with-a-tnf-mediated-proteomic-signaling-response
#3
Lisa Smeester, Paige A Bommarito, Elizabeth M Martin, Rogelio Recio-Vega, Tania Gonzalez-Cortes, Edgar Olivas-Calderon, R Clark Lantz, Rebecca C Fry
Exposure to inorganic arsenic (iAs) in drinking water is a global public health concern and is associated with a range of health outcomes, including immune dysfunction. Children are a particularly sensitive population to the effects of inorganic arsenic, yet the biological mechanisms underlying adverse health outcomes are understudied. Here we used a proteomic approach to examine the effects of iAs exposure on circulating serum protein levels in a cross-sectional children's cohort in Mexico. To identify iAs-associated proteins, levels of total urinary arsenic (U-tAs) and its metabolites were determined and serum proteins assessed for differences in expression...
April 8, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28432993/chemical-biological-and-dna-markers-for-tracing-slaughterhouse-effluent
#4
P J Harvey, M P Taylor, H K Handley, S Foster, M R Gillings, A J Asher
Agricultural practices, if not managed correctly, can have a negative impact on receiving environments via waste disposal and discharge. In this study, a chicken slaughter facility on the rural outskirts of Sydney, Australia, has been identified as a possible source of persistent effluent discharge into a peri-urban catchment. Questions surrounding the facility's environmental management practices go back more than four decades. Despite there having never been a definitive determination of the facility's impact on local stream water quality, the New South Wales Environment Protection Authority (NSW EPA) has implemented numerous pollution reduction requirements to manage noise and water pollution at the slaughter facility...
April 19, 2017: Environmental Research
https://www.readbyqxmd.com/read/28432964/phytate-induced-arsenic-uptake-and-plant-growth-in-arsenic-hyperaccumulator-pteris-vittata
#5
Xue Liu, Jing-Wei Fu, Ni Tang, E B da Silva, Yue Cao, Benjamin L Turner, Yanshan Chen, Lena Q Ma
Phytate is abundant in soils, which is stable and unavailable for plant uptake. However, it occurs in root exudates of As-hyperaccumulator Pteris vittata (PV). To elucidate its effect on As uptake and growth, P. vittata were grown on agar media (63 μM P) containing 50 μM As and/or 50 or 500 μM phytate with non As-hyperaccumulator Pteris ensiformis (PE) as a congeneric control for 60 d. Phytate induced efficient As and P uptake, and enhanced growth in PV, but had little effects on PE. The As concentrations in PV fronds and roots were 157 and 31 mg kg(-1) in As50+phytate50, 2...
April 19, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28432892/arsenic-chromium-molybdenum-and-selenium-geochemical-fractions-and-potential-mobilization-in-riverine-soil-profiles-originating-from-germany-and-egypt
#6
Sabry M Shaheen, Eilhann E Kwon, Jayanta K Biswas, Filip M G Tack, Yong Sik Ok, Jörg Rinklebe
The fractionation and potential mobilization of As, Cr, Mo, and Se in four floodplain soil profiles collected along the Nile (Egypt) and Wupper (Germany) Rivers were assessed using the BCR sequential extraction procedure. The concentrations of total and the geochemical fractions (acid soluble (F1), reducible (F2), oxidizable (F3), and residual (F4) fraction) of the elements were determined. The Wupper soils had the highest total concentrations (mg kg(-1)) of As (378) and Cr (2,797) while the Nile soils contained the highest total Mo (12) and Se (42)...
April 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28432891/modification-of-an-existing-in%C3%A2-vitro-method-to-predict-relative-bioavailable-arsenic-in-soils
#7
Shane Whitacre, Nicholas Basta, Brooke Stevens, Valerie Hanley, Richard Anderson, Kirk Scheckel
The soil matrix can sequester arsenic (As) and reduces its exposure by soil ingestion. In vivo dosing studies and in vitro gastrointestinal (IVG) methods have been used to predict relative bioavailable (RBA) As. Originally, the Ohio State University (OSU-IVG) method predicted RBA As for soils exclusively from mining and smelting sites with a median of 5,636 mg As kg(-1). The objectives of the current study were to (i) evaluate the ability of the OSU-IVG method to predict RBA As for As contaminated soils with a wider range of As content and As contaminant sources, and (ii) evaluate a modified extraction procedure's ability to improve prediction of RBA As...
April 3, 2017: Chemosphere
https://www.readbyqxmd.com/read/28432518/correlation-between-heavy-metal-exposure-and-gstm1-polymorphism-in-iranian-multiple-sclerosis-patients
#8
Mehdi Aliomrani, Mohammad A Sahraian, Hamid Shirkhanloo, Mohammad Sharifzadeh, Mohammad R Khoshayand, Mohammad H Ghahremani
Multiple sclerosis (MS) is an immune-mediated chronic inflammatory disease of the central nervous system. Various exposures to heavy metals can lead to toxicity and oxidative stress. While glutathione-S-transferases are known as oxidative stress-related genes and involved in metal biotransformation. The aim of the present study is to investigate the correlation of GSTM1 polymorphism in MS patients and the possible association with blood concentration of arsenic (As) and cadmium (Cd) as major heavy metal pollutants...
April 21, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28432307/arsenic-metabolism-in-high-altitude-modern-stromatolites-revealed-by-metagenomic-analysis
#9
Daniel Kurth, Ariel Amadio, Omar F Ordoñez, Virginia H Albarracín, Wolfgang Gärtner, María E Farías
Modern stromatolites thrive only in selected locations in the world. Socompa Lake, located in the Andean plateau at 3570 masl, is one of the numerous extreme Andean microbial ecosystems described over recent years. Extreme environmental conditions include hypersalinity, high UV incidence, and high arsenic content, among others. After Socompa's stromatolite microbial communities were analysed by metagenomic DNA sequencing, taxonomic classification showed dominance of Proteobacteria, Bacteroidetes and Firmicutes, and a remarkably high number of unclassified sequences...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28431363/nanomaterial-based-electrochemical-sensors-for-arsenic-a-review
#10
REVIEW
Sureshkumar Kempahanumakkagari, Akash Deep, Ki-Hyun Kim, Suresh Kumar Kailasa, Hye-On Yoon
The existence of arsenic in the environment poses severe global health threats. Considering its toxicity, the sensing of arsenic is extremely important. Due to the complexity of environmental and biological samples, many of the available detection methods for arsenic have serious limitations on selectivity and sensitivity. To improve sensitivity and selectivity and to circumvent interferences, different electrode systems have been developed based on surface modification with nanomaterials including carbonaceous nanomaterials, metallic nanoparticles (MNPs), metal nanotubes (MNTs), and even enzymes...
April 13, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28431356/heavy-metals-pollution-levels-and-children-health-risk-assessment-of-yerevan-kindergartens-soils
#11
Gevorg Tepanosyan, Nairuhi Maghakyan, Lilit Sahakyan, Armen Saghatelyan
Children, the most vulnerable urban population group, are exceptionally sensitive to polluted environments, particularly urban soils, which can lead to adverse health effects upon exposure. In this study, the total concentrations of Ag, As, Ba, Cd, Co, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, Ti, V, and Zn were determined in 111 topsoil samples collected from kindergartens in Yerevan. The objectives of this study were to evaluate heavy metal pollution levels of kindergarten's soils in Yerevan, compare with national legal and international requirements on heavy metal contents in kindergarten soil, and assess related child health risk...
April 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28431349/impacts-of-environmental-factors-on-arsenate-biotransformation-and-release-in-microcystis-aeruginosa-using-the-taguchi-experimental-design-approach
#12
Zhenhong Wang, Zhuanxi Luo, Changzhou Yan, Baoshan Xing
Very limited information is available on how and to what extent environmental factors influence arsenic (As) biotransformation and release in freshwater algae. These factors include concentrations of arsenate (As(V)), dissolved inorganic nitrogen (N), phosphate (P), and ambient pH. This study conducted a series of experiments using Taguchi methods to determine optimum conditions for As biotransformation. We assessed principal effective factors of As(V), N, P, and pH and determined that As biotransformation and release actuate at 10...
April 18, 2017: Water Research
https://www.readbyqxmd.com/read/28427227/high-dose-ascorbate-and-arsenic-trioxide-selectively-kill-acute-myeloid-leukemia-and-acute-promyelocytic-leukemia-blasts-in-vitro
#13
Nélida I Noguera, Elvira Pelosi, Daniela F Angelini, Maria Liliana Piredda, Gisella Guerrera, Eleonora Piras, Luca Battistini, Lauretta Massai, Anna Berardi, Gianfranco Catalano, Laura Cicconi, Germana Castelli, Agnese D'Angiò, Luca Pasquini, Grazia Graziani, Giuseppe Fioritoni, Maria Teresa Voso, Domenico Mastrangelo, Ugo Testa, Francesco Lo-Coco
The use of high-dose ascorbate (ASC) for the treatment of human cancer has been attempted several decades ago and has been recently revived by several in vitro and in vivo studies in solid tumors. We tested the cytotoxic effects of ASC, alone or in combination with arsenic trioxide (ATO) in acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL). Leukemic cell lines and primary blasts from AML and APL patients were treated with graded concentrations of ASC, alone or in association with standard concentration (1 μM) of ATO...
March 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28426741/as3mt-mediated-tolerance-to-arsenic-evolved-by-multiple-independent-horizontal-gene-transfers-from-bacteria-to-eukaryotes
#14
Michael Palmgren, Karin Engström, Björn M Hallström, Karin Wahlberg, Dan Ariel Søndergaard, Torbjörn Säll, Marie Vahter, Karin Broberg
Organisms have evolved the ability to tolerate toxic substances in their environments, often by producing metabolic enzymes that efficiently detoxify the toxicant. Inorganic arsenic is one of the most toxic and carcinogenic substances in the environment, but many organisms, including humans, metabolise inorganic arsenic to less toxic metabolites. This multistep process produces mono-, di-, and trimethylated arsenic metabolites, which the organism excretes. In humans, arsenite methyltransferase (AS3MT) appears to be the main metabolic enzyme that methylates arsenic...
2017: PloS One
https://www.readbyqxmd.com/read/28425042/arsenic-trioxide-induced-rhabdomyolysis-a-rare-but-severe-side-effect-in-an-apl-patient-a-case-report
#15
Haiyan He, Ran An, Jian Hou, Weijun Fu
Arsenic trioxide (ATO), a component of the traditional Chinese medicine arsenic sublimate, promotes apoptosis and induces leukemic cell differentiation. Combined with all-trans-retinotic acid (ATRA), ATO has become the first-line induction therapy in treating acute promyelocytic leukemia (APL). The most common side effects of ATO include hepatotoxicity, gastrointestinal symptoms, water-sodium retention, and nervous system damage. In this report, we present a rare side effect, rhabdomyolysis, in a 68-year-old female APL patient who was treated with ATO...
April 19, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28424837/arsenic-cadmium-chromium-lead-mercury-and-selenium-concentrations-in-pine-snakes-pituophis-melanoleucus-from-the-new-jersey-pine-barrens
#16
Joanna Burger, Michael Gochfeld, Christian Jeitner, Robert Zappalorti, Taryn Pittfield, Emile DeVito
Top trophic level predators are at risk from bioaccumulation of heavy metals from their prey. Using nondestructively collected tissues as a method of assessing metal concentrations in snakes is useful for populations that are threatened or declining. This paper reports concentrations of arsenic (As), cadmium (Cd), chromium (Cr), lead (Pb), mercury (Hg), and selenium (Se) in tissues of Northern pine snakes (Pituophis melanoleucus) from the New Jersey Pine Barrens, a relatively pristine, undisturbed habitat. We also determined if skin is an appropriate indicator of internal concentrations and identified the factors (tissue, year of collection, length, sex) that might explain variations in metal concentrations...
April 19, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28424825/a-magnetized-nanoparticle-based-solid-phase-extraction-procedure-followed-by-inductively-coupled-plasma-atomic-emission-spectrometry-to-determine-arsenic-lead-and-cadmium-in-water-milk-indian-rice-and-red-tea
#17
Salameh Azimi, Zarrin Es'haghi
A sensitive and simple method using magnetic multi-walled carbon nanotube (MWCNTs-Fe3O4 MNP), as the adsorbent, has been successfully developed for extraction and pre-concentration of arsenic, lead and cadmium with detection by inductively coupled plasma-atomic emission spectroscopy (ICP-AES). The nanosorbent was characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction pattern (XRD), vibrating sample magnetometer (VSM) and transmission electron microscopy (TEM). The key factors affecting the signal intensity such as pH, adsorbent amount, etc...
April 19, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28424000/heavy-metals-and-pahs-in-canned-fish-supplies-on-the-serbian-market
#18
Nikolina J Novakov, Željko A Mihaljev, Brankica D Kartalović, Bojan J Blagojević, Jelana M Petrović, Miroslav A Ćirković, Dragan R Rogan
The aim of this study was to determine the level of heavy metals and PAHs in 57 samples of canned tuna, 25 samples of canned sardines and 16 samples of canned smoked sprouts, collected from supermarkets in Serbia. Heavy metal levels (lead, cadmium, mercury, arsenic, iron, copper and zinc) were determined using an ICP-MS method. Sixteen analyzed PAHs were determined using a GC-MS method. The trace elements in canned fish were in the range (mg kg(-1)) of 0.01-0.28 for lead, 0.003-0.08 for cadmium, 0.007-0.64 for mercury, 0...
April 20, 2017: Food Additives & Contaminants. Part B, Surveillance
https://www.readbyqxmd.com/read/28423485/m2-polarization-of-macrophages-facilitates-arsenic-induced-cell-transformation-of-lung-epithelial-cells
#19
Jiajun Cui, Wenhua Xu, Jian Chen, Hui Li, Lu Dai, Jacqueline A Frank, Shaojun Peng, Siying Wang, Gang Chen
The alterations in microenvironment upon chronic arsenic exposure may contribute to arsenic-induced lung carcinogenesis. Immune cells, such as macrophages, play an important role in mediating the microenvironment in the lungs. Macrophages carry out their functions after activation. There are two activation status for macrophages: classical (M1) or alternative (M2); the latter is associated with tumorigenesis. Our previous work showed that long-term arsenic exposure induces transformation of lung epithelial cells...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423108/-potential-health-risks-from-consumption-of-water-with-arsenic-in-colima-mexico
#20
Oliver Mendoza-Cano, Ramón Alberto Sánchez-Piña, Julián Barrón-Quintana, Herguin Benjamin Cuevas-Arellano, Pilar Escalante-Minakata, Ramón Solano-Barajas
Objective: To estimate potential health risks due to chronic ingestion of arsenic from groundwater in Colima, Mexico. Materials and methods: Samples were randomly taken in 36 wells from 10 local aquifers. Analysis was performed by ICP-OES following international standards. Geostatistical interpolation was performed with ArcGIS, implementing a model weighting inverse distance to estimate arsenic routes of exposure and consumption on each locality. The Hazard Quotient Ratio (HQ) and carcinogenic risk (R) for As were estimated...
January 2017: Salud Pública de México
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