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https://www.readbyqxmd.com/read/29353273/metabolomics-in-sepsis-and-its-impact-on-public-health
#1
Nikolaos Evangelatos, Pia Bauer, Matthias Reumann, Kapaettu Satyamoorthy, Hans Lehrach, Angela Brand
Sepsis, with its often devastating consequences for patients and their families, remains a major public health concern that poses an increasing financial burden. Early resuscitation together with the elucidation of the biological pathways and pathophysiological mechanisms with the use of "-omics" technologies have started changing the clinical and research landscape in sepsis. Metabolomics (i.e., the study of the metabolome), an "-omics" technology further down in the "-omics" cascade between the genome and the phenome, could be particularly fruitful in sepsis research with the potential to alter the clinical practice...
January 19, 2018: Public Health Genomics
https://www.readbyqxmd.com/read/29353157/phytochemical-analysis-of-salal-berry-gaultheria-shallon-pursh-a-traditionally-consumed-fruit-from-western-north-america-with-exceptionally-high-proanthocyanidin-content
#2
Andrew Ferguson, Elisabete Carvalho, Geraldine Gourlay, Vincent Walker, Stefan Martens, Juha-Pekka Salminen, C Peter Constabel
Salal (Gaultheria shallon Pursh.) is a wild perennial shrub of the Ericaceae and common in coastal forests of western North America, and its berries were an important traditional food for First Nations in British Columbia. Salal berries were investigated for phytochemical content and antioxidant capacity over the course of fruit development. The proanthocyanidin content was extremely high in young berries (280.7 mg/g dry wt) but dropped during development to 52.8 mg/g dry wt. By contrast, anthocyanins accumulated only at the late berry stages...
January 17, 2018: Phytochemistry
https://www.readbyqxmd.com/read/29352945/silylation-and-characterization-of-microcrystalline-cellulose-isolated-from-indonesian-native-oil-palm-empty-fruit-bunch
#3
Septi Pujiasih, Kurnia, Abu Masykur, Triana Kusumaningsih, Ozi Adi Saputra
Silylation of microcrystalline cellulose (MCC), isolated from Indonesian native oil palm empty fruit bunch (OPEFB), using aminosilane compound synthesized through aminolysis of 3-glycidoxypropyltrimethoxysilane (GPTMS) with ethylenediamine (EDA) has been conducted in this study. Generally, there are three steps performed to isolate MCC before silylation process, i.e. bleaching, alkaline treatment and acid hydrolysis. All products resulted from bleaching, alkaline and acid hydrolysis treatments were characterized using Fourier Transform Infrared (FTIR) spectroscopy...
March 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29352909/a-review-of-polysaccharides-from-schisandra-chinensis-and-schisandra-sphenanthera-properties-functions-and-applications
#4
REVIEW
Zijian Li, Xin He, Fei Liu, Jue Wang, Juan Feng
Schisandra is an herbal plant resource with dual functions in medicine and food since ancient times. It has a variety of healthcare and therapeutic effects. Schisandra chinensis (Turcz.) Baill and Schisandra sphenanthera Rehd. et Wits are two of the most commonly used Schisandra. Traditional Chinese medicine experience has shown that water-soluble polysaccharide from Schisandra may be one of its main components with pharmacological effects. Progress in the industrial production and extraction process of plant polysaccharides, especially Chinese medicine polysaccharides in the past three decades, have led to many new discoveries about Schisandra polysaccharides in the fields of purification and identification...
March 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29352831/associations-between-adherence-to-the-danish-food-based-dietary-guidelines-and-cardiometabolic-risk-factors-in-a-danish-adult-population-the-dipi-study
#5
Johanne L Arentoft, Camilla Hoppe, Elisabeth W Andersen, Kim Overvad, Inge Tetens
Diet is recognised as one modifiable lifestyle factor for ischaemic heart disease (IHD). We aimed at investigating the associations between adherence to the Danish Food-Based Dietary Guidelines (FBDG) indicated by a Dietary Quality Index (DQI) and selected cardiometabolic risk factors in a cross-sectional study with 219 Danish adult participants (59 %women; age 31-65years) with a minimum of one self-rated risk marker of IHD. Information regarding diet was obtained using web-based dietary assessment software and adherence to the Danish FBDG was expressed by a DQI calculated from 5 food and nutrient indicators (whole grain, fish, fruit and vegetables, energy from saturated fat and from added sugar)...
January 21, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29352820/concordance-and-predictors-of-concordance-of-children-s-dietary-intake-as-reported-via-ecological-momentary-assessment-and-24-h-recall
#6
Sydney G O'Connor, Wangjing Ke, Eldin Dzubur, Susan Schembre, Genevieve F Dunton
OBJECTIVE: To provide preliminary evidence in support of using ecological momentary assessment (EMA), a real-time data capture method involving repeated assessments, to measure dietary intake in children by examining the concordance of children's dietary reports through EMA and 24 h recall. DESIGN: Children completed eight days of EMA surveys, reporting on recent dietary intake of four pre-specified food categories ('Fruits or Vegetables', 'Chips or Fries', 'Pastries or Sweets', 'Soda or Energy Drinks'), and completed two 24 h recalls during the same period...
January 21, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29352819/dietary-fibre-intake-in-relation-to-the-risk-of-incident-chronic-kidney-disease
#7
Parvin Mirmiran, Emad Yuzbashian, Golaleh Asghari, Shaghayegh Sarverzadeh, Fereidoun Azizi
The purpose of this study was primarily to evaluate the association of total fibre intake with the risk of incident chronic kidney disease (CKD). We also evaluated the association of dietary fibre from fruits, vegetables, cereals and legumes with the incidence of CKD in a population-based prospective study. We followed up 1630 participants of the Tehran Lipid and Glucose Study for 6·1 years, who were initially free of CKD. Baseline diet was assessed by a valid and reliable FFQ. Estimated glomerular filtration rate (eGFR) was calculated, using the Modification of Diet in Renal Disease Study equation, and CKD was defined as eGFR <60 ml/min per 1·73 m2...
January 21, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29352462/effect-of-methyl-salicylate-in-combination-with-1-methylcyclopropene-on-postharvest-quality-and-decay-caused-by-botrytis-cinerea-in-tomato-fruit
#8
Dedong Min, Fujun Li, Xinhua Zhang, Pan Shu, Xixi Cui, Lulu Dong, Chuntao Ren, Demei Meng, Jian Li
BACKGROUND: Postharvest diseases result in major losses in fruits. Tomato is susceptible to postharvest rot caused by B. cinerea and is regarded as a good model system to study postharvest disease and quality deterioration in fruit. To develop a safe and effective technique to alleviate disease and maintain fruit quality, the effects of methyl salicylate (MeSA) or 1-methylcyclopropene (1-MCP) either separately or combined on quality and gray mold caused by B. cinerea in tomato fruit were investigated...
January 20, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29352383/dietary-patterns-their-covariates-and-associations-with-severity-of-depressive-symptoms-among-university-students-in-lebanon-a-cross-sectional-study
#9
Doris Jaalouk, Jocelyne Matar Boumosleh, Lea Helou, Maya Abou Jaoude
PURPOSE: The study aims to identify dietary patterns in university students in Lebanon, to determine their associations with socio-demographic, lifestyle, and stress factors, and to assess the link between identified dietary patterns and severity of depressive symptoms, controlling for multiple confounders. METHODS: Four hundred and fifty-seven private university students were surveyed. Information about dietary intake, socio-demographic and lifestyle factors, physical activity, and depressive symptoms were collected by the 73-item food frequency questionnaire, background questionnaire, International Physical Activity Questionnaire-Short Form, and Patient Health Questionnaire (PHQ-9), respectively...
January 19, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29352085/the-expression-of-bacteriocin-production-and-self-resistance-in-lactobacillus-brevis-174a-is-mediated-by-two-regulatory-proteins
#10
Masafumi Noda, Rumi Miyauchi, Narandalai Danshiitsoodol, Yasuyuki Matoba, Takanori Kumagai, Masanori Sugiyama
We have previously shown that a lactic acid bacterium Lactobacillus (Lb.) brevis 174A isolated from a Citrus iyo fruit produces bacteriocin designated brevicin 174A, which is comprised of two antibacterial polypeptides (designated brevicin 174A-β and 174A-γ). We have also found a gene cluster, composed of eight open reading frames (ORFs), that contains genes for the biosynthesis of brevicin 174A, self-resistance to its own bacteriocin, and two transcriptional regulatory proteins.Some lactic acid bacterial strains have a system to start the production of bacteriocin at an adequate stage of the growth...
January 19, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29351650/are-evidence-based-community-engaged-energy-balance-interventions-enough-for-extremely-vulnerable-populations
#11
Nancy E Schoenberg, Yelena N Tarasenko, Claire Snell-Rood
Well-documented associations between lifestyle behaviors and disease outcomes necessitate evidence-based health promotion interventions. To enhance potential efficacy and effectiveness, interventionists increasingly respond to community priorities, employ comprehensive theoretical frameworks, invest heavily to ensure cultural fit, implement evidence-based programming, and deploy research gold standards. We describe a project that followed all of these recommended strategies, but did not achieve desired outcomes...
January 17, 2018: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/29351247/b-type-and-complex-a-b-type-epicatechin-trimers-isolated-from-litchi-pericarp-aqueous-extract-show-high-antioxidant-and-anticancer-activity
#12
Yihui Gong, Fang Fang, Xin Zhang, Bin Liu, Honghui Luo, Zhen Li, Xuelian Zhang, Zhaoqi Zhang, Xuequn Pang
Litchi (Litchi chinensis Sonn.) fruit is known for its rich source of phenolics. Litchi pericarp contains high levels of epicatechin that may form oligomers of various lengths. Except for several A or B type epicatechin dimers, other soluble oligomers have rarely been identified in the pericarp. Here, bioassay-guided column fractionation was applied to isolate bioactive phenolics from aqueous pericarp extract. A fraction (S3) was obtained by two rounds of Sephadex LH-20 column chromatography, and showed higher antioxidant activity and inhibition on the proliferation of human lung cancer cells (A549) than Litchi anthocyanins...
January 19, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29351232/dietary-acid-load-and-potassium-intake-associate-with-blood-pressure-and-hypertension-prevalence-in-a-representative-sample-of-the-german-adult-population
#13
Danika Krupp, Jonas Esche, Gert Bernardus Maria Mensink, Stefanie Klenow, Michael Thamm, Thomas Remer
Diets rich in fruits and vegetables, like the Dietary Approaches to Stop Hypertension (DASH)-diet, are usually characterized by high potassium intake and reduced dietary acid load, and have been shown to reduce blood pressure (BP). However, the relevance of potential renal acid load (PRAL) for BP has not been compared with the relevance to BP of urinary biomarker (K-urine)- and dietary food frequency questionnaire (K-FFQ)-based estimates of potassium intake in a general adult population sample. For 6788 participants (aged 18-79 years) of the representative German Health-Interview and Examination Survey for Adults (DEGS1), associations of PRAL, K-urine, and K-FFQ with BP and hypertension prevalence were cross-sectionally examined in multivariable linear and logistic regression models...
January 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29350762/occurrence-of-ochratoxins-fumonisin-b2-aflatoxins-b1-and-b2-and-other-secondary-fungal-metabolites-in-dried-date-palm-fruits-from-egypt-a-mini-survey
#14
Mohamed F Abdallah, Rudolf Krska, Michael Sulyok
This study was conducted to investigate the natural co-occurrence of 295 fungal and bacterial metabolites in 28 samples of dried date palm fruits collected from different shops distributed in Assiut Governorate, Upper Egypt in 2016. Extraction and quantification of the target analytes were done using the "dilute and shoot" approach followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. In total, 30 toxic fungal metabolites were detected. Among these metabolites, 4 types of ochratoxins including ochratoxin type A and B were quantified in 3 samples (11%) with a contamination range from 1...
January 19, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29350757/hepatoprotective-effects-of-sophoricoside-against-fructose-induced-liver-injury-via-regulating-lipid-metabolism-oxidation-and-inflammation-in-mice
#15
Wenfeng Li, Yalong Lu
The dried fruit of Sophora japonica L. is a traditional Chinese herb tea rich in sophoricoside that is an isoflavone glycoside. The aim of current study was to investigate the hepatic protective effect of sophoricoside in high fructose (HF) diet fed mice. Healthy male mice were fed 30% fructose water and treated 80 and 160 mg/kg·bw sophoricoside continuously for 8 wk. Our data showed that administration of sophoricoside at 80 and 160 mg/kg·bw observably decreased the body weight and liver weight in HF-fed mice...
January 19, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29350299/mutagenicity-cytotoxic-and-antioxidant-activities-of-ricinus-communis-different-parts
#16
Mazhar Abbas, Abid Ali, Muhammad Arshad, Asia Atta, Zahed Mehmood, Imtiaz Mahmood Tahir, Munawar Iqbal
Ricinus communis (castor plant) is a potent medicinal plant, which is commonly used in the treatment of various ailments. The present study was conducted to appraise the cytotoxicity and mutagenicity of R. communis along with antioxidant and antimicrobial activities. Cytotoxicity was evaluated by hemolytic and brine shrimp assays, whereas Ames test (TA98 and TA100) was used for mutagenicity evaluation. Plant different parts were extracted in methanol by shaking, sonication and Soxhlet extraction methods. The R...
January 19, 2018: Chemistry Central Journal
https://www.readbyqxmd.com/read/29350294/biocatalysis-of-aromatic-benzyl-propionate-ester-by-different-immobilized-lipases
#17
Amanda Gomes Almeida Sá, Alessandra Cristina de Meneses, Lindomar Alberto Lerin, Pedro Henrique Hermes de Araújo, Cláudia Sayer, Débora de Oliveira
Benzyl propionate is an aromatic ester that possesses a fruity odor and is usually found in nature in the composition of some fruits such as plums and melons. This work aimed for the benzyl propionate synthesis by esterification using a new immobilized enzyme preparation with low-cost material from Candida antarctica (NS 88011) and three commercial immobilized lipases (Novozym 435, Lipozyme TL-IM and Lipozyme RM-IM). Novozym 435 had the best performance even when the solvent tert-butanol was absent of the reaction medium...
January 19, 2018: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/29350256/analysis-of-phenolic-compounds-in-different-parts-of-pomegranate-punica-granatum-fruit-by-hplc-pda-esi-ms-and-evaluation-of-their-antioxidant-activity-application-to-different-italian-varieties
#18
Marina Russo, Chiara Fanali, Giusy Tripodo, Paola Dugo, Rosario Muleo, Laura Dugo, Laura De Gara, Luigi Mondello
The analysis of pomegranate phenolic compounds belonging to different classes in different fruit parts was performed by high-performance liquid chromatography coupled with photodiode array and mass spectrometry detection. Two different separation methods were optimized for the analysis of anthocyanins and hydrolyzable tannins along with phenolic acids and flavonoids. Two C18 columns, core-shell and fully porous particle stationary phases, were used. The parameters for separation of phenolic compounds were optimized considering chromatographic resolution and analysis time...
January 19, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29350067/soluble-neuregulin1-is-strongly-up-regulated-in-the-rat-model-of-charcot-marie-tooth-1a-disease
#19
Benedetta Elena Fornasari, Giulia Ronchi, Davide Pascal, Davide Visigalli, Giovanna Capodivento, Lucilla Nobbio, Isabelle Perroteau, Angelo Schenone, Stefano Geuna, Giovanna Gambarotta
Neuregulin1 (NRG1) is a growth factor playing a pivotal role in peripheral nerve development through the activation of the transmembrane co-receptors ErbB2-ErbB3. Soluble NRG1 isoforms, mainly secreted by Schwann cells, are strongly and transiently up-regulated after acute peripheral nerve injury, thus suggesting that they play a crucial role also in the response to nerve damage. Here we show that in the rat experimental model of the peripheral demyelinating neuropathy Charcot-Marie-Tooth 1A (CMT1A) the expression of the different NRG1 isoforms (soluble, type α and β, type a and b) is strongly up-regulated, as well as the expression of NRG1 co-receptors ErbB2-ErbB3, thus showing that CMT1A nerves have a gene expression pattern highly reminiscent of injured nerves...
January 1, 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29350017/skin-prick-test-analysis-reveals-cross-sensitization-to-tomato-profilin-and-grass-pollen-in-nasobronchialallergic-patients-with-history-of-tomato-food-allergy
#20
V L Hegde, P A Mahesh, Y P Venkatesh
The association between grass pollen sensitization and food allergy to tomato is of great interest. We report here, the first such study in Indian population. We investigated 246 allergic rhinitis / asthma patients by diagnostic case history and skin prick test (SPT); grass pollen mix, tomato extract and purified tomato profilin were used for SPT. Tomato profilin was purified by affinity chromatography, and analyzed by HPLC (95% purity) and SDS-PAGE (14 kDa). We observed that 38% of the patients had sensitization to both grass pollen and tomato fruit, of which 92% were sensitized to tomato profilin...
January 2018: European Annals of Allergy and Clinical Immunology
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