keyword
MENU ▼
Read by QxMD icon Read
search

Non-clinical

keyword
https://www.readbyqxmd.com/read/28545743/tdap-vaccination-among-healthcare-personnel-internet-panel-survey-2012-2014
#1
Anup Srivastav, Carla L Black, Peng-Jun Lu, Jun Zhang, Jennifer L Liang, Stacie M Greby
INTRODUCTION: Healthcare personnel (HCP) are at risk for pertussis infection exposure or transmitting the disease to patients in their work settings. The Advisory Committee on Immunization Practices recommends tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccination for HCP to minimize these risks. This study assessed Tdap vaccination coverage among U.S. HCP by sociodemographic and occupation-related characteristics. METHODS: The 2012, 2013, and 2014 Internet Panel Surveys were analyzed in 2015 to assess HCP Tdap vaccination...
May 23, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28545545/a-focused-ethnography-of-a-child-and-adolescent-mental-health-service-factors-relevant-to-the-implementation-of-a-depression-trial
#2
C E W Kitchen, S Lewis, P A Tiffin, P R Welsh, L Howey, D Ekers
BACKGROUND: Prior to commencing a randomised controlled trial, we conducted a focused ethnography to ensure that the trial was well suited to the proposed setting. METHODS: A six-month observation of a Child and Adolescent Mental Health Service site in the North-East of England was undertaken to observe the site procedures, staff culture and patient care pathways. During this period, documentary data were collected and interviews were conducted with key informants to provide insight into staff perceptions of the proposed trial...
May 25, 2017: Trials
https://www.readbyqxmd.com/read/28542508/the-measurement-of-alexithymia-in-children-and-adolescents-psychometric-properties-of-the-alexithymia-questionnaire-for-children-and-the-twenty-item-toronto-alexithymia-scale-in-different-non-clinical-and-clinical-samples-of-children-and-adolescents
#3
Gwenolé Loas, Stéphanie Braun, Marie Delhaye, Paul Linkowski
This study had two aims. Firstly, the psychometric properties of the 20-item Toronto Alexithymia Scale (TAS-20) and the Alexithymia Questionnaire for Children (AQC) that measure the three dimensions of alexithymia (DIF, difficulty identifying feelings; DDF, difficulty describing feelings; EOT, externally-oriented thinking) were explored in various samples of children, adolescents or young adults to detect the best factor-structure and to examine if the Externally-Oriented Thinking (EOT) factor must be deleted or not...
2017: PloS One
https://www.readbyqxmd.com/read/28540501/morphometric-characterization-of-rat-and-human-alveolar-macrophage-cell-models-and-their-response-to-amiodarone-using-high-content-image-analysis
#4
Ewelina Hoffman, Aateka Patel, Doug Ball, Jan Klapwijk, Val Millar, Abhinav Kumar, Abigail Martin, Rhamiya Mahendran, Lea Ann Dailey, Ben Forbes, Victoria Hutter
PURPOSE: Progress to the clinic may be delayed or prevented when vacuolated or "foamy" alveolar macrophages are observed during non-clinical inhalation toxicology assessment. The first step in developing methods to study this response in vitro is to characterize macrophage cell lines and their response to drug exposures. METHODS: Human (U937) and rat (NR8383) cell lines and primary rat alveolar macrophages obtained by bronchoalveolar lavage were characterized using high content fluorescence imaging analysis quantification of cell viability, morphometry, and phospholipid and neutral lipid accumulation...
May 24, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28539173/wearables-for-independent-living-in-older-adults-gait-and-falls
#5
REVIEW
A Godfrey
Solutions are needed to satisfy care demands of older adults to live independently. Wearable technology (wearables) is one approach that offers a viable means for ubiquitous, sustainable and scalable monitoring of the health of older adults in habitual free-living environments. Gait has been presented as a relevant (bio)marker in ageing and pathological studies, with objective assessment achievable by inertial-based wearables. Commercial wearables have struggled to provide accurate analytics and have been limited by non-clinically oriented gait outcomes...
June 2017: Maturitas
https://www.readbyqxmd.com/read/28536985/anterior-segment-optical-coherence-tomography-and-retained-vegetal-intraocular-foreign-body-masquerading-as-chronic-anterior-uveitis
#6
Anis Mahmoud, Riadh Messaoud, Fatma Abid, Imen Ksiaa, Melek Bouzayene, Moncef Khairallah
BACKGROUND: The purpose of this single case report was to report the use of anterior segment optical coherence tomography for the diagnosis and management of a retained vegetal intraocular foreign body. RESULTS: A 23-year-old otherwise healthy male presented with a progressive vision loss in the right eye (RE). He reported a mild ocular trauma with a tree leaf 1 year ago followed by recurrent episodes of redness and pain in the RE that partially resolved after a self-medication with topical steroids...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28533946/rethinking-social-cognition-in-light-of-psychosis-reciprocal-implications-for-cognition-and-psychopathology
#7
Vaughan Bell, Kathryn L Mills, Gemma Modinos, Sam Wilkinson
The positive symptoms of psychosis largely involve the experience of illusory social actors and yet our current measures of social cognition, at best, only weakly predict their presence. We review evidence to suggest that the range of current approaches in social cognition is not sufficient to explain the fundamentally social nature of these experiences. We argue that social agent representation is an important organising principle for understanding social cognition and that alterations in social agent representation may be a factor in the formation of delusions and hallucination in psychosis...
May 2017: Clinical Psychological Science
https://www.readbyqxmd.com/read/28533120/evaluation-of-new-chemical-entities-as-substrates-of-liver-transporters-in-the-pharmaceutical-industry-response-to-regulatory-requirements-and-future-steps
#8
Noriko Okudaira
This article discusses the evaluation of drug candidates as hepatic transporter substrates. Recently, research on the applications of hepatic transporters in the pharmaceutical industry has improved to meet the requirements of the regulatory guidelines for the evaluation of drug interactions. To identify the risk of transporter-mediated drug-drug interactions (DDIs) at an early stage of drug development, we employed a strategy of reviewing the in vivo animal pharmacokinetics and tissue distribution data obtained in the discovery stage together with the in vitro data obtained for regulatory submission...
May 19, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28530346/-seeds-of-mindfulness-in-the-desert-preliminary-results-from-a-clinical-trial-in-the-mindfulness-clinic-mental-health-center-beer-sheva
#9
Lee Tibi Cohen, Keren Reiner Noy, Ayelet Shmulevich, Oded Arbel
INTRODUCTION: Mindfulness-based therapies are rooted in the Buddhist tradition, and promote cultivation of qualities such as open awareness, acceptance and compassion. While various studies have demonstrated the efficacy of integrating mindfulness in therapeutic practice for people suffering from clinical conditions such as depression and anxiety as well as the non-clinical population, this was rarely replicated in Israel. In the Mindfulness Clinic, located in the Mental Health Center, Beer Sheva, mindfulness workshops are now available for diverse populations dealing with various challenges such as daily stress, chronic pain, and depression...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28526056/the-blood-schizonticidal-activity-of-tafenoquine-makes-an-essential-contribution-to-its-prophylactic-efficacy-in-nonimmune-subjects-at-the-intended-dose-200%C3%A2-mg
#10
REVIEW
Geoffrey Dow, Bryan Smith
Tafenoquine (TQ) is an 8-aminoquinoline anti-malarial being developed for malaria prophylaxis. It has been generally assumed that TQ, administered prophylactically, acts primarily on the developing exoerythrocytic stages of malaria parasites (causal prophylaxis), and that polymorphisms in metabolic enzymes thought to impact the activity of other 8-aminoquinolines also inhibit this property of TQ. Furthermore, it has been suggested that a diagnostic test for CYP2D6 metabolizer status might be required. In field studies in which metabolic status was not an exclusion criteria, TQ has been shown to exhibit similar prophylactic efficacy as blood schizonticidal drugs (mefloquine)...
May 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28511739/self-critical-thinking-and-overgeneralization-in-depression-and-eating-disorders-an-experimental-study
#11
Graham R Thew, James D Gregory, Kate Roberts, Katharine A Rimes
BACKGROUND: Self-critical thinking is common across psychological disorders. This study hypothesized that it may play an important role in 'overgeneralization', the process of drawing general implications from an isolated negative experience. AIMS: To explore the impact of two experimental tasks designed to elicit self-critical thoughts on the endorsement of general negative self-views of clinical and non-clinical populations. METHOD: Three groups (depression, eating disorders and non-clinical controls), completed standardized questionnaires and the two tasks...
May 17, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28511035/on-the-context-dependency-of-implicit-self-esteem-in-social-anxiety-disorder
#12
Thomas S Hiller, Melanie C Steffens, Viktoria Ritter, Ulrich Stangier
BACKGROUND AND OBJECTIVES: Cognitive models assume that negative self-evaluations are automatically activated in individuals with Social Anxiety Disorder (SAD) during social situations, increasing their individual level of anxiety. This study examined automatic self-evaluations (i.e., implicit self-esteem) and state anxiety in a group of individuals with SAD (n = 45) and a non-clinical comparison group (NC; n = 46). METHODS: Participants were randomly assigned to either a speech condition with social threat induction (giving an impromptu speech) or to a no-speech condition without social threat induction...
May 5, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28509664/reliability-of-the-dissociative-trance-disorder-interview-schedule-a-preliminary-report
#13
Colin A Ross, Eli Somer, Caitlin Goode
One hundred inpatients in a hospital-based Trauma Program in the United States were interviewed with the Dissociative Trance Disorder Interview Schedule (DTDIS). There were no significant differences for the DTDIS total score or any of the subscale scores on test-retest: all t values comparing the two administrations of the DTDIS were below 0.7, and all p values were above 0.5. Cronbach's alpha for the US sample was .966 and for the Israeli sample it was .971. The findings indicate that the DTDIS has good reliability and may be suitable for use in cross-cultural research, however the results require replication by independent researchers in a variety of cultures and languages, and in both clinical and non-clinical samples...
May 16, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28509616/depersonalization-adversity-emotionality-and-coping-with-stressful-situations
#14
Paula Thomson, S Victoria Jaque
Depersonalization is defined as persistent or recurrent episodes of feeling detached or estranged from a sense of self and the world. This study addressed the primary question: Do non-clinical individuals who endorse high symptomatic depersonalization have inherently more intense emotional responses, along with more childhood adversity and past trauma? In this IRB approved study, participants who met clinical levels of depersonalization (n = 43, 16.3%) were compared to a group without clinical levels of depersonalization (n = 221, 83...
May 16, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28507528/cognitive-impairments-in-occupational-burnout-error-processing-and-its-indices-of-reactive-and-proactive-control
#15
Krystyna Golonka, Justyna Mojsa-Kaja, Magda Gawlowska, Katarzyna Popiel
The presented study refers to cognitive aspects of burnout as the effects of long-term work-related stress. The purpose of the study was to investigate electrophysiological correlates of burnout to explain the mechanisms of the core burnout symptoms: exhaustion and depersonalization/cynicism. The analyzed error-related electrophysiological markers shed light on impaired cognitive mechanisms and the specific changes in information-processing in burnout. In the EEG study design (N = 80), two components of error-related potential (ERP), error-related negativity (ERN), and error positivity (Pe), were analyzed...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28507356/school-going-adolescents-perception-of-family-climate-and-mental-problems-results-from-kocaeli-turkey
#16
Safak Eray, Ayse Pinar Vural, Deniz Sigirli
OBJECTIVE: To investigate the association between the perception of expressed emotion and psychopathology of school-going adolescents in a non-clinical sample. METHODS: The cross-sectional field study was conducted in Kocaeli, Turkey, and comprised high-school students during the 2014-15 school years. Data was collected using the Information Collection Form, Strengths and Difficulties Questionnaire and Shortened Level of Expressed Emotion Scale. SPSS 21 was used for data analysis...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28506887/molecular-investigation-of-virulence-factors-of-brucella-melitensis-and-brucella-abortus-strains-isolated-from-clinical-and-non-clinical-samples
#17
Reza Mirnejad, Faramarz Masjedian Jazi, Shayan Mostafaei, Mansour Sedighi
Brucella is zoonotic pathogen that induces abortion and sterility in domestic mammals and chronic infections in humans called Malta fever. It is a facultative intracellular potential pathogen with high infectivity. The virulence of Brucella is dependent upon its potential virulence factors such as enzymes and cell envelope associated virulence genes. The aim of this study was to investigate the Brucella virulence factors among strains isolated from humans and animals in different parts of Iran. Seventy eight strains of Brucella species isolated from suspected human and animal cases from several provinces of Iran during 2015-2016 and identified by phenotypic and molecular methods...
May 12, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28506817/in-vitro-cyp-mediated-drug-metabolism-in-the-zebrafish-embryo-using-human-reference-compounds
#18
Moayad Saad, An Matheeussen, Sebastiaan Bijttebier, Evy Verbueken, Casper Pype, Christophe Casteleyn, Chris Van Ginneken, Sandra Apers, Louis Maes, Paul Cos, Steven Van Cruchten
The increasing use of zebrafish embryos as an alternative model for toxicological and pharmacological studies necessitates a better understanding of xenobiotic biotransformation in this species. As cytochrome P450 enzymes (CYPs) play an essential role in this process, in vitro drug metabolism of four human CYP-specific substrates, i.e. dextromethorphan (DXM), diclofenac (DIC), testosterone (TST) and midazolam (MDZ) was investigated in adult male and female zebrafish, and in zebrafish embryos and larvae up to 120hours post-fertilization...
May 12, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28503141/addiction-as-an-attachment-disorder-white-matter-impairment-is-linked-to-increased-negative-affective-states-in-poly-drug-use
#19
Human-Friedrich Unterrainer, Michaela Hiebler-Ragger, Karl Koschutnig, Jürgen Fuchshuber, Sebastian Tscheschner, Maria Url, Jolana Wagner-Skacel, Eva Z Reininghaus, Ilona Papousek, Elisabeth M Weiss, Andreas Fink
Substance use disorders (SUD) have been shown to be linked to various neuronal and behavioral impairments. In this study, we investigate whether there is a connection between the integrity of white matter (WM) and attachment styles as well as different affective states including spirituality in a group of patients diagnosed for poly-drug use disorder (PUD) in comparison to non-clinical controls. A total sample of 59 right-handed men, comprising the groups of patients with PUD (n = 19), recreational drug-using individuals (RUC; n = 20) as well as non-drug using controls were recruited (NUC; n = 20)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28502866/what-is-inappropriate-hospital-use-for-elderly-people-near-the-end-of-life-a-systematic-review
#20
REVIEW
Magnolia Cardona-Morrell, James C H Kim, Mikkel Brabrand, Blanca Gallego-Luxan, Ken Hillman
BACKGROUND: Older people with advance chronic illness use hospital services repeatedly near the end of life. Some of these hospitalizations are considered inappropriate. AIM: To investigate extent and causes of inappropriate hospital admission among older patients near the end of life. METHODS: English language publications in Medline, EMBASE, PubMed, Cochrane library, and the grey literature (January 1995-December 2016) covering community and nursing home residents aged ≥60years admitted to hospital...
May 11, 2017: European Journal of Internal Medicine
keyword
keyword
20016
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"