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Spinal column injury

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https://www.readbyqxmd.com/read/29227787/major-destructive-asymptomatic-lumbar-charcot-lesion-treated-with-three-column-resection-and-short-segment-reconstruction-case-report-treatment-strategy-and-review-of-literature
#1
Kestutis Valancius, Gaurav Garg, Madalina Duicu, Ebbe Stender Hansen, Cody Bunger
Charcot's spine is a long-term complication of spinal cord injury. The lesion is often localized at the caudal end of long fusion constructs and distal to the level of paraplegia. However, cases are rare and the literature relevant to the management of Charcot's arthropathy is limited. This paper reviews the clinical features, diagnosis, and surgical management of post-traumatic spinal neuroarthropathy in the current literature. We present a rare case of adjacent level Charcot's lesion of the lumbar spine in a paraplegic patient, primarily treated for traumatic spinal cord lesion 39 years before current surgery...
2017: SICOT-J
https://www.readbyqxmd.com/read/29200479/management-of-sub-axial-cervical-spine-injuries
#2
Gautam Zaveri, Gurdip Das
Sub-axial cervical spine injuries are commonly seen in patients with blunt trauma. They may be associated with spinal cord injury resulting in tetraplegia and severe permanent disability. Immobilization of the neck, maintenance of blood pressure and oxygenation, rapid clinical and radiological assessment of all injuries, and realignment of the spinal column are the key steps in the emergency management of these injuries. The role of intravenous methylprednisolone administration in acute spinal cord injuries remains controversial...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29184051/clinical-efficacy-of-anterior-partial-corpectomy-and-titanium-mesh-fusion-and-internal-fixation-for-treatment-of-old-fracture-dislocation-of-the-lower-cervical-spine
#3
De-Chao Miao, Bao-Yang Zhang, Tao Lei, Yong Shen
BACKGROUND The aim of this study was to analyze the clinical features and to evaluate the efficacy of anterior partial corpectomy and titanium mesh fusion and internal fixation of old fracture dislocation of the lower cervical spine. MATERIAL AND METHODS We retrospectively analyzed the clinical data of 52 patients with old lower cervical fracture and dislocation treated with anterior partial corpectomy and titanium mesh fusion fixation between January 2008 and December 2013, with a mean follow-up period of 4...
November 29, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29183676/depolarization-and-electrical-stimulation-enhance-in-vitro-and-in-vivo-sensory-axon-growth-after-spinal-cord-injury
#4
Ioana Goganau, Beatrice Sandner, Norbert Weidner, Karim Fouad, Armin Blesch
Activity dependent plasticity is a key mechanism for the central nervous system (CNS) to adapt to its environment. Whether neuronal activity also influences axonal regeneration in the injured CNS, and whether electrical stimulation (ES) can activate regenerative programs in the injured CNS remains incompletely understood. Using KCl-induced depolarization, in vivo ES followed by ex-vivo neurite growth assays and ES after spinal cord lesions and cell grafting, we aimed to identify parameters important for ES-enhanced neurite growth and axonal regeneration...
November 26, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/29180614/isolated-c5-vertebrae-dislocation-with-trauma-an-extremely-rare-case-of-isolated-c5-dislocation
#5
Selçuk Özdoğan, Mustafa Kaya, Nail Demirel, Ali Haluk Düzkalır, Cumhur Kaan Yaltırık
BACKGROUND Total spondylolisthesis, or dislocation of 1 cervical vertebrae, is only caused by high-energy trauma and is usually fatal. Cervical spine fractures and dislocations often cause 3-column structural damage to the cervical spine, injury to the spinal cord, and precipitating alignment of the cervical vertebrae, as well as cervical instability, which are detrimental, show poor prognosis, and are associated with high rates of mortality rate and disability. CASE REPORT We report an extremely rare case of isolated C5 dislocation caused by falling out of a tree, with sudden tetraplegia...
November 28, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29165712/use-of-an-articulating-hinge-to-facilitate-cervicothoracic-deformity-correction-during-vertebral-column-resection
#6
Rajiv R Iyer, Benjamin D Elder, Tomas Garzon-Muvdi, Justin M Sacks, Ian Suk, Jean-Paul Wolinsky
BACKGROUND: Surgical treatment of severe cervicothoracic kyphotic deformity may require the use of 3-column osteotomies such as the pedicle subtraction osteotomy and vertebral column resection (VCR), or VCR with anterior longitudinal ligament resection. Such procedures are extensive and are associated with high intra- and perioperative morbidity, in part, due to the need for risky reduction maneuvers. OBJECTIVE: To describe a novel technique utilizing a laterally placed articulating hinge to facilitate kyphotic deformity correction of the cervicothoracic spine...
November 18, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29080262/new-evidence-for-preserved-somatosensory-pathways-in-complete-spinal-cord-injury-a-fmri-study
#7
Paul J Wrigley, Philip J Siddall, Sylvia M Gustin
Trauma to the spinal cord rarely results in complete division of the cord with surviving nerves sometimes remaining silent or failing to function normally. The term motor or sensory discomplete has been used to describe this important but unclassified subgroup of complete SCI. Importantly, silent motor or sensory pathways may contribute to aversive symptoms (spasticity, pain) or improved treatment success. To demonstrate more objectively the presence of subclinical preserved somatosensory pathways in clinically complete SCI, a cross-sectional study using functional MRI (fMRI) was undertaken...
October 28, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29069968/corrigendum
#8
(no author information available yet)
Eglseder, K., & Demchick, B. (2017). Sexuality and Spinal Cord Injury: The Lived Experiences of Intimate Partners. Occupation, Participation and Health, 37, 5-16. doi: 10.1177/1539449217701394 This article that appeared in Issue 37:3 of Occupation, Participation and Health has the following corrected information: On p. 126, in the first sentence of the last paragraph under Procedures, the text "The current study was approved by the BLIND University" should instead read, "The current study was approved by the Towson University" On p...
October 1, 2017: OTJR: Occupation, Participation and Health
https://www.readbyqxmd.com/read/29055739/mesenchymal-progenitor-cells-primed-with-pentosan-polysulfate-promote-lumbar-intervertebral-disc-regeneration-in-an-ovine-model-of-microdiscectomy
#9
Chris D Daly, Peter Ghosh, Andrew C W Zannettino, Tanya Badal, Ronald Shimmon, Graham Jenkin, David Oehme, Kanika Jain, Idrees Sher, Angela Vais, Camilla Cohen, Ronil V Chandra, Tony Goldschlager
BACKGROUND CONTEXT: Neural compression associated with lumbar disc herniation is usually managed surgically by microdiscectomy. However, 10 - 20% patients re-present with debilitating back pain and approximately 15% require further surgery. PURPOSE: Using an ovine model of microdiscectomy, the present study investigated the relative potential of pentosan polysulfate primed mesenchymal progenitor cells (pMPCs) or MPC alone implanted into the lesion site, to facilitate disc recovery...
October 18, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29045569/altered-expression-of-reorganized-inputs-as-they-ascend-from-the-cuneate-nucleus-to-cortical-area-3b-in-monkeys-with-long-term-spinal-cord-injuries
#10
Priyabrata Halder, Niranjan Kambi, Prem Chand, Neeraj Jain
Chronic deafferentations in adult mammals result in reorganization of the brain. Lesions of the dorsal columns of the spinal cord at cervical levels in monkeys result in expansion of the intact chin inputs into the deafferented hand representation in area 3b, second somatosensory (S2) and parietal ventral (PV) areas of the somatosensory cortex, ventroposterior lateral nucleus (VPL) of the thalamus, and cuneate nucleus of the brainstem. Here, we describe the extent and nature of reorganization of the cuneate and gracile nuclei of adult macaque monkeys with chronic unilateral lesions of the dorsal columns, and compare it with the reorganization of area 3b in the same monkeys...
October 13, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29038239/correlated-disruption-of-resting-state-fmri-lpf-and-spike-connectivity-between-area-3b-and-s2-following-spinal-cord-injury-in-monkeys
#11
Ruiqi Wu, Pai-Feng Yang, Li Min Chen
This study aims to understand how functional connectivity (FC) between areas 3b and S2 alters following input-deprivation and the neuronal basis of disrupted FC of resting state fMRI signals. We combined submillimeter fMRI with microelectrode recordings to localize the deafferented digit regions in areas 3b and S2 by mapping tactile stimulus-evoked fMRI activations before and after cervical dorsal column lesion (DCL) in each male monkey. An average afferents disruption of 97% significantly reduced fMRI, LFP and spike responses to stimuli in both areas...
October 16, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28965444/intraoperative-neuromonitoring-alerts-in-a-pediatric-deformity-center
#12
Maria Zuccaro, James Zuccaro, Amer F Samdani, Joshua M Pahys, Steven W Hwang
OBJECTIVE Intraoperative neuromonitoring (IONM) involves the use of somatosensory evoked potentials (SSEPs) and transcranial electric motor evoked potentials (TceMEPs). In this retrospective study the authors examined the sensitivity and specificity of both SSEPs and TceMEPs during pediatric spinal deformity surgeries. METHODS The authors performed a retrospective quantitative analysis of data obtained in 806 patients (197 males and 609 females) treated from December 2011 until October 2015. All patients were diagnosed with scoliosis that was classified as one of the following: adolescent idiopathic scoliosis (AIS) (38%), congenital scoliosis (22%), or syndromic scoliosis (40%)...
October 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28958356/trauma-spinal-cord-injury
#13
REVIEW
Matthew J Eckert, Matthew J Martin
Injuries to the spinal column and spinal cord frequently occur after high-energy mechanisms of injury, or with lower-energy mechanisms, in select patient populations like the elderly. A focused yet complete neurologic examination during the initial evaluation will guide subsequent diagnostic procedures and early supportive measures to help prevent further injury. For patients with injury to bone and/or ligaments, the initial focus should be spinal immobilization and prevention of inducing injury to the spinal cord...
October 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28937458/transpedicular-corpectomy-and-cage-placement-in-the-treatment-of-traumatic-lumbar-burst-fractures
#14
Martin H Pham, Alexander Tuchman, Thomas C Chen, Frank L Acosta, Patrick C Hsieh, John C Liu
STUDY DESIGN: Retrospective review. OBJECTIVE: To review the feasibility of a posterior-only approach for instrumented reconstruction in lumbar burst fractures. BACKGROUND: Burst fractures of the lumbar spine have been treated through a variety of techniques, including anterior, posterior, or combined approaches. Here we review series of patients undergoing posterior-only transpedicular corpectomy with instrumented fusion for traumatic lumbar burst fracture...
October 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28935824/effects-of-expiratory-muscle-activation-via-high-frequency-spinal-cord-stimulation
#15
Krzysztof E Kowalski, Jaroslaw Richard Romaniuk, Tomasz Kowalski, Anthony F DiMarco
In persons with spinal cord injury, lower thoracic low frequency spinal cord stimulation (LF-SCS, 50Hz,15mA) is a useful method to restore an effective cough. Unfortunately, the high stimulus amplitude requirements and potential activation of pain fibers significantly limits this application in persons with intact sensation. In this study, the mechanism of the expiratory muscle activation, via high frequency SCS (HF-SCS;500Hz,1mA) was evaluated in dogs. In group one, the effects of electrode placement on airway pressure generation (P) was evaluated...
September 21, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28913694/emergency-neurological-life-support-traumatic-spine-injury
#16
Deborah M Stein, William A Knight
Traumatic spine injuries (TSIs) carry significantly high risks of morbidity, mortality, and exorbitant health care costs from associated medical needs following injury. For these reasons, TSI was chosen as an ENLS protocol. This article offers a comprehensive review on the management of spinal column injuries using the best available evidence. Though the review focuses primarily on cervical spinal column injuries, thoracolumbar injuries are briefly discussed as well. The initial emergency department (ED) clinical evaluation of possible spinal fractures and cord injuries, along with the definitive early management of confirmed injuries, are also covered...
September 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28895456/spatial-and-cellular-expression-patterns-of-erythropoietin-receptor-and-erythropoietin-during-a-42-day-post-lesional-time-course-after-graded-thoracic-spinal-cord-impact-lesions-in-the-rat
#17
Gesa Cohrs, Stephan Goerden, Ralf Lucius, Michael Synowitz, Maximilian Hubertus Mehdorn, Janka Held-Feindt, Friederike Knerlich-Lukoschus
Erythropoietin (Epo) exhibits promising neuroregenerative potential for spinal cord injury (SCI) and might be involved in other long-term sequelae, such as neuropathic pain development. The current studies investigated the time courses and spatial and cellular patterns of Epo and EpoR expression along the spinal axis after graded SCI. Male Long Evans rats received 100-kdyn, 150-kdyn, and 200-kdyn thoracic (T9) contusions from an Infinite Horizon Impactor. Sham controls received laminectomies. Anatomical and quantitative immunohistochemical analyses of the EpoR/Epo expression along the whole spinal axis were performed 7, 15, and 42 DPO after the lesioning...
September 12, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28846013/feasibility-and-data-quality-of-the-national-spinal-cord-injury-registry-of-iran-nscir-ir-a-pilot-study
#18
Khatereh Naghdi, Zahra Azadmanjir, Soheil Saadat, Aidin Abedi, Sahar Koohi Habibi, Pegah Derakhshan, Mahdi Safdarian, Shayan Abdollah Zadegan, Abbas Amirjamshidi, Mahdi Sharif-Alhoseini, Jalil Arab Kheradmand, Mahdi Mohammadzadeh, Kazem Zendehdel, Zahra Khazaeipour, Seyed Mahmood Ramak Hashemi, Hooshang Saberi, Kourosh Karimi Yarandi, Seyed Ebrahim Ketabchi, Shahrokh Yousefzadeh-Chabok, Hamid Heidari, Arezo Sotodeh, Khalil Pestei, Zahra Ghodsi, Farideh Sadeghian, Vanessa Noonan, Edward C Benzel, Gerard Oreilly, Jens Chapman, Ellen Merete Hagen, Michael G Fehlings, Alexander R Vaccaro, Morteza Faghih Jooybari, Mohammad Reza Zarei, Mohammad Reza Zafarghandi, Payman Salamati, Saeed Nezareh, Moein Khormali, Mohsen Sadeghi-Naini, Seyed Behzad Jazayeri, Bizhan Aarabi, Vafa Rahimi-Movaghar
BACKGROUND: Spinal cord injury (SCI) is one of the most disabling consequences of trauma with unparalleled economic, social, and personal burden. Any attempt aimed at improving quality of care should be based on comprehensive and reliable data. This pilot investigation studied the feasibility of implementing the National Spinal Cord and Column Injury Registry of Iran (NSCIR-IR) and scrutinized the quality of the registered data. METHODS: From October 2015 to May 2016, over an 8-month period, 65 eligible trauma patients who were admitted to hospitals in three academic centers in mainland Iran were included in this pilot study...
August 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28817819/progressive-kyphosis-associated-with-tethered-cord-syndrome-treated-by-posterior-vertebral-column-resection-in-a-pediatric-patient
#19
Kadir Oktay, Kerem Mazhar Ozsoy, Yurdal Gezercan, Nuri Eralp Cetinalp, Tahsin Erman
Posterior vertebral column resection is a novel surgical approach for the treatment of progressive kyphosis associated with tethered cord syndrome that was first treated with untethering surgery. A patient with tethered cord syndrome associated with kyphosis first underwent untethering surgery, resulting in progressive kyphosis. Posterior vertebral column resection was performed to correct the kyphosis while shortening the spinal column to prevent the spinal cord from stretch injury. Good correction of kyphosis and reduction of tension on the neural elements were achieved without any neurological deficits...
2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28816877/fractures-in-spinal-ankylosing-disorders-a-narrative-review-of-disease-and-injury-types-treatment-techniques-and-outcomes
#20
Tarush Rustagi, Doniel Drazin, Cumhur Oner, Jonathan York, Gregory D Schroeder, Alexander R Vaccaro, Rod J Oskouian, Jens R Chapman
INTRODUCTION: Spinal ankylosing disorders encompass ankylosing spondylitis (AS), disseminated hyperostosis of the spine, and end-stage spondylosis. All these result in a stiffened and frequently deformed spinal column. This makes the spinal column highly susceptible to severe injuries that are commonly associated with unfavorable outcomes. Improved understanding of the underlying disease processes and clinical comorbidities may alter the poor injury related morbidity and mortality outcomes...
September 2017: Journal of Orthopaedic Trauma
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