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https://www.readbyqxmd.com/read/28816288/-recombinant-human-transforming-growth-factor-%C3%AE-1-promotes-dental-pulp-stem-cells-proliferation-and-mineralization
#1
W Q Jia, Y M Zhao, L H Ge
OBJECTIVE: To explore suitable concentration of recombinant human transforming growth factor β1 (rhTGF-β1) usage and study the effect of rhTGF-β1 on differentiation of dental pulp stem cells (DPSCs). METHODS: DPSCs were isolated from the undiseased third molars of people aged 18-25 years and cultured according to instructions in vitro. Different concentrations (1 , 6 , 10 μg/L) of rhTGF-β1 were added to the culture medium to examine DPSCs proliferation by CCK-8 (cell counting kit-8) assay...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28815884/periodontal-ligament-like-tissue-regeneration-with-drilled-porous-decalcified-dentin%C3%A2-matrix-sheet-composite
#2
Ge Feng, Yan Wu, Yu Yong, Lan Huang, Shu An, Bo Hu, Jun Luo, Jinlin Song
OBJECTIVE: In this study, we constructed a composite by combining the human dental follicle cell sheet and a manual drilled porous decalcified dentin matrix that was used to construct ectopic tissue-engineered periodontal ligament-like tissues in renal capsules of nude mice. MATERIALS AND METHODS: Human dental follicle cells were harvested from human lower third molars and then embedded into a temperature-sensitive culture dish. These cells were then placed into frozen porous decalcified dentin matrix sheets and induced by 50 g/ml ascorbic acid...
August 16, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28813110/trait-vs-state-anxiety-in-different-threatening-situations
#3
Pollyana Caldeira Leal, Tiago Costa Goes, Luiz Carlos Ferreira da Silva, Flavia Teixeira-Silva
Objective: Anxiety as a uni- or multidimensional construct has been under discussion. The unidimensional approach assumes that there is a general trait anxiety, which predisposes the individuals to increases in state anxiety in various threatening situations. In this case, there should be a correlation between state and trait anxiety in any situation of threat. Therefore, the aim of this study was to investigate the correlation between trait and state anxiety in participants exposed to two different anxiogenic situations: interpersonal threat (Video-Monitored Stroop Test - VMST) and physical threat (third molar extraction - TME)...
August 14, 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28812130/studies-on-the-radiographic-visibility-of-the-periodontal-ligament-in-lower-third-molars-can-the-olze-method-be-used-in-the-chinese-population
#4
Yu-Cheng Guo, Mu-Jia Li, Andreas Olze, Sven Schmidt, Ronald Schulz, Hong Zhou, Heidi Pfeiffer, Teng Chen, Andreas Schmeling
The purpose of the present research is to study the radiographic visibility of the periodontal ligament in third molars from a northern Chinese population to determine if this methodology could be used for the 18-year threshold. A total of 1300 conventional orthopantomograms from 650 males and 650 females of northern Chinese subjects aged between 15 and 40 years were analyzed. The radiographic visibility of the periodontal membrane of fully mineralized third molars was assessed using the stages described by Olze et al...
August 15, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28811076/submucosal-injection-of-dexamethasone-and-methylprednisolone-for-the-control-of-postoperative-sequelae-after-third-molar-surgery-randomized-controlled-trial
#5
A Chugh, S Singh, Y Mittal, V Chugh
Pain, swelling, and trismus are known sequelae of third molar surgery that can significantly affect the individual's quality of life (QOL). These should be minimized to improve QOL. The purpose of this study was to compare the effects of the preoperative submucosal administration of equivalent doses of two commonly used steroids on these postoperative sequelae. A randomized controlled clinical trial was conducted involving 60 subjects requiring the removal of impacted mandibular third molars. Extraction cases with a similar difficulty index were included...
August 12, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28809370/marsupialization-facilitates-movement-of-the-cystic-lesion-associated-deeply-impacted-mandibular-third-molar-in-spite-of-its-mature-roots
#6
R Sun, Y Cai, Y Wu, J-H Zhao
BACKGROUND: The odontogenic cystic lesions happened in the angle and ramus region are frequently associated with impacted mandibular third molars. The treatment plan was difficult to work out for the huge cystic lesions with deeply impacted third molars, since the enucleation with simultaneously removing the deeply impacted teeth may cause serious complications. Therefore, the marsupialization of the cystic lesions followed by enucleation with tooth removal has also been advocated. The aim of this study was to explore the movement of cystic lesion-associated deeply impacted mandibular third molars (IMTM) after marsupialization...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28809364/clinician-related-factors-behind-the-decision-to-extract-an-asymptomatic-lower-third-molar-a-cross-sectional-study-based-on-spanish-and-portuguese-dentists
#7
D Alves-Pereira, D Pereira-Silva, R Figueiredo, C Gay-Escoda, E Valmaseda-Castellón
BACKGROUND: Scientific literature estimates that around 18 to 40 % of asymptomatic third molars are extracted. The aims of the present study were to determine the indications for extraction of asymptomatic lower third molars in a sample of Spanish and Portuguese dentists, and to relate these indications to the clinicians' training and professional experience. MATERIAL AND METHODS: A survey consisting of 15 cases of asymptomatic lower third molars was emailed to Portuguese and Spanish dentists...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28808452/root-morphology-and-canal-configuration-of-first-and-second-maxillary-molars-in-a-selected-iranian-population-a-cone-beam-computed-tomography-evaluation
#8
Abbasali Khademi, Asieh Zamani Naser, Zahra Bahreinian, Mojdeh Mehdizadeh, Mojtaba Najarian, Saber Khazaei
INTRODUCTION: The aim of this investigation was to evaluate root canal morphology of maxillary first and second molars and also to assess the prevalence and morphology of the second mesiobuccal canal (MB2) in these teeth, using cone-beam computed tomography (CBCT). METHODS AND MATERIALS: In this cross-sectional study, the total of 470 CBCT images from the archive of Radiology Department of Isfahan University of Medical Sciences (IUMS), Iran, was evaluated and 295 images were selected...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28805281/efficacy-and-safety-of-a-fixed-dose-combination-of-ibuprofen-and-caffeine-in-the-management-of-moderate-to-severe-dental-pain-after-third-molar-extraction
#9
T Weiser, E Richter, A Hegewisch, D D Muse, R Lange
BACKGROUND: Ibuprofen is an effective analgesic treatment with a ceiling effect at doses above 400 mg. This study compared the combination of ibuprofen 400 mg and caffeine 100 mg with ibuprofen 400 mg monotherapy, caffeine and placebo in the analgesic treatment of moderate to severe acute dental pain following third molar extraction. METHODS: Phase III, active-/placebo-controlled, double-blind, single-centre, two-stage, parallel-group study in adult patients with at least moderate baseline pain intensity...
August 14, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28805103/dentoalveolar-oral-surgery-in-children-and-adolescents-organization-and-surgical-treatment-in-a-large-danish-municipal-dental-service
#10
Anni Birgitte Grønbæk, Flemming Petersen, Dorte Haubek, Sven Poulsen
OBJECTIVE: To describe a population-based organization of dentoalveolar surgical service for 0 to 18-year old subjects in a Danish municipal dental service, and analyze the type of dentoalveolar surgical interventions needed. MATERIAL AND METHODS: The study was conducted in the Municipality of Aarhus, Denmark during five consecutive school-years. An internal referral system was established within the municipality where patients could be referred to colleagues with a higher level of competencies and more experiences with paediatric dentoalveolar surgery...
August 13, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28804693/the-ability-of-reciproc-instruments-to-reach-full-working-length-without-glide-path-preparation-a-clinical-retrospective-study
#11
Andreas Bartols, Bernt-Peter Robra, Winfried Walther
BACKGROUND: Reciproc instruments are the only contemporary root canal instruments where glide path preparation is no longer strictly demanded by the manufacturer. As the complete preparation of root canals is associated with success in endodontic treatment we wanted to assess the ability and find predictors for Reciproc instruments to reach full working length (RFWL) in root canals of maxillary molars in primary root canal treatment (1°RCTx) and retreatment (2°RCTx) cases. METHODS: This retrospective study evaluated 255 endodontic treatment cases of maxillary molars...
2017: PeerJ
https://www.readbyqxmd.com/read/28797219/unresolving-trismus-following-third-molar-surgery-report-of-a-case-of-fibrodysplasia-ossificans-progressiva-with-review-of-literature
#12
B R Rajanikanth, Kavitha Prasad, K Vineeth, Sushma M N Sonale, Khuteja Al-Kubra
BACKGROUND: Trismus is a problem commonly encountered by the dental practitioner. It has a number of potential causes, and its treatment will depend on the cause. However, there are very few reports of trismus due to fibrodysplasia ossificans progressiva (FOP) following third molar surgery. CLINICAL PRESENTATION: FOP is a rare human genetic disorder with characteristic clinical features like progressive formation of extraskeletal bone or heterotopic ossification and congenital malformation of the great toes...
August 11, 2017: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/28796346/fracture-of-nickel-titanium-rotary-instrument-during-root-canal-treatment-and-re-treatment-a-5-year-retrospective-study
#13
K Alfouzan, A Jamleh
AIM: To evaluate retrospectively the incidence of K3 nickel titanium rotary instrument fracture in referred cases during root canal treatment and re-treatment. METHODOLOGY: Clinical and radiographic reports of 12867 endodontic cases treated at the King Abdulaziz medical city between January 2010 and November 2015 were reviewed to obtain information on intra-canal fractured instruments with respect to the treatment performed, tooth type, and the size and at what level the instrument fractured (coronal, middle or apical)...
August 10, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28794794/sfrp2-enhances-the-osteogenic-differentiation-of-apical-papilla-stem-cells-by-antagonizing-the-canonical-wnt-pathway
#14
Luyuan Jin, Yu Cao, Guoxia Yu, Jinsong Wang, Xiao Lin, Lihua Ge, Juan Du, Liping Wang, Shu Diao, Xiaomeng Lian, Songlin Wang, Rui Dong, Zhaochen Shan
BACKGROUND: Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs). Our previous study on dental tissue-derived MSCs demonstrated that secreted frizzled-related protein 2 (SFRP2), a Wnt inhibitor, could enhance osteogenic differentiation in stem cells from the apical papilla (SCAPs). However, how SFRP2 promotes osteogenic differentiation of dental tissue-derived MSCs remains unclear...
2017: Cellular & Molecular Biology Letters
https://www.readbyqxmd.com/read/28791081/is-the-late-mandibular-fracture-from-third-molar-extraction-a-risk-towards-malpractice-case-report-with-the-analysis-of-ethical-and-legal-aspects
#15
Weuler Dos Santos Silva, Rubens Jorge Silveira, Michelle Gouveia Benicio de Araujo Andrade, Ademir Franco, Rhonan Ferreira Silva
OBJECTIVES: The present study reports a case of late mandibular fracture due to third molar extraction and highlights the inherent clinical, ethical and legal aspects related to this surgical complication. MATERIAL AND METHODS: A female patient underwent surgical procedure for the extraction of the mandibular right third molar. Two days after the surgery the patient reported pain and altered occlusion in the right side of the mandible. After clinical and radiographic re-examination, the diagnosis of late mandibular fracture was established...
April 2017: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/28782906/differentiation-of-human-dental-pulp-stem-cells-into-neuronal-by-resveratrol
#16
Ya-Wei Geng, Zhen Zhang, Ming-Yue Liu, Wei-Ping Hu
Dental pulp stem cells (DPSCs) have been proposed as a promising source of stem cells in nerve regeneration due to their close embryonic origin and ease of harvest. Resveratrol (RSV) is a natural polyphenolic and possesses many biological functions such as anti-inflammatory activity and protection against atherosclerosis and neuroprotective activities. There is increasing evidence showing that RSV plays a pivotal role in neuron protection and neuronal differentiation. In this study, we isolated DPSCs from impacted third molars and investigated whether RSV induces neuronal differentiation of DPSCs...
August 7, 2017: Cell Biology International
https://www.readbyqxmd.com/read/28781844/third-molar-transplantation-combined-with-an-osteotome-sinus-lift-two-case-reports
#17
Katsuki Yamamoto, Yoshinaga Osamu, Kae Kakura, Kazuko Yamamoto, Hirofumi Kido
We report here on our application of the socket lift technique to create a transplant socket for the transplanted maxillary molar. These outcomes suggest that this technique is likely to be effective for tooth transplantation when the maxillary sinus bottom is close to the alveolar crest.
August 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28772088/effect-of-zoledronate-a-third-generation-bisphosphonate-on-proliferation-and-apoptosis-of-human-dental-pulp-stem-cells
#18
Solmaz Pourgonabadi, Seyed Hadi Mousavi, Zahra Tayarani Najaran, Ahmad Ghorbani
Clinical use of zoledronate is accompanied with osteonecrosis of the jaw but the pathogenesis is not well understood. We assumed that zoledronate may have cytotoxicity against stem cells of the oral cavity, and in this way helps to initiate or promoting osteonecrosis. Dental pulp stem cells (DPSCs) and gingival fibroblasts (GFs) were isolated from volunteers who were undergoing third molar extraction. The proliferation of DPSCs and GFs was evaluated using thiazolyl blue tetrazolium bromide assay. Effect of zoledronate on apoptosis was determined by propidium iodide staining and western blotting analysis...
August 3, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28771709/assessment-of-the-referral-system-for-surgical-removal-of-third-molars-at-the-dental-faculty-king-saud-university
#19
Randa Abdul Moein Al Fotawi, Manju Roby Philip, Sangeetah Negavara Premnath
INTRODUCTION: There is compelling evidence that prophylactic extraction of third molars is a health problem that needs to be addressed. In particular, the vast amount of evidence demonstrating complications after removal of third molars, rather than supporting the necessity of removal or the negative effects of retention, raise this concern. OBJECTIVE: The aim of this study was to investigate the referral system for third molar extraction at our institution by assessing patient opinions and the experience of the oral surgeons and the referring dentists...
August 2, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28770156/platelet-rich-fibrin-in-the-management-of-established-dry-socket
#20
Srinivas Chakravarthi
OBJECTIVES: Dry socket may occur secondary to the removal of any tooth. However, most dry socket cases develop in the third molar region. Dry socket is multifactorial in nature and has been treated using various modalities with varying success rates. This study assessed the efficacy of platelet rich fibrin (PRF) in established dry socket. MATERIALS AND METHODS: Ten patients of either sex aged from 41 to 64 years with established dry socket according to established criteria were treated using PRF...
June 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
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