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https://www.readbyqxmd.com/read/29240687/decreasing-inappropriate-use-of-antibiotics-in-primary-care-in-four-countries-in-south-america-cluster-randomized-controlled-trial
#1
Inés Urbiztondo, Lars Bjerrum, Lidia Caballero, Miguel Angel Suarez, Monica Olinisky, Gloria Córdoba
High antibiotic prescribing and antimicrobial resistance in patients attending primary care have been reported in South America. Very few interventions targeting general practitioners (GPs) to decrease inappropriate antibiotic prescribing have been investigated in this region. This study assessed the effectiveness of online feedback on reducing antibiotic prescribing in patients with suspected respiratory tract infections (RTIs) attending primary care. The aim was to reduce antibiotic prescribing in patients with acute bronchitis and acute otitis media...
December 14, 2017: Antibiotics
https://www.readbyqxmd.com/read/29238681/comparative-study-of-outcome-of-type-i-tympanoplasty-in-chronic-otitis-media-active-mucosal-disease-wet-ear-versus-chronic-otitis-media-inactive-mucosal-disease-dry-ear
#2
Yojana Sharma, Girish Mishra, Jaykumar V Patel
To compare the outcome of type I tympanoplasty with cortical mastoidectomy in chronic otitis media active mucosal disease (wet ear) versus chronic otitis media inactive mucosal disease (dry ear). An observational analytic study was conducted and data collection was done from August 2014 to August 2016. All patients of chronic otitis media with mucosal disease were divided into two groups, one with active disease (group A) and another with inactive disease (group B). The outcome was studied in the form of graft take up rate...
December 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29235932/retrospective-study-of-the-presentation-diagnosis-and-management-of-16-cats-with-otitis-media-not-due-to-nasopharyngeal-polyp
#3
Nicola Swales, Aiden Foster, Natalie Barnard
Objectives The aim of this study was to analyse retrospectively cats diagnosed with otitis media (OM) not due to nasopharyngeal polyp, and to review the clinical outcome with surgical and medical management. Methods Patient records were searched for cats diagnosed with OM. The diagnosis of OM was based on the presence of clinical signs, including neurological signs, respiratory signs and signs of otitis externa, and on the basis of evidence of thickened or irregular bullae walls, or the presence of fluid within the tympanic cavity; in those that had diagnostic imaging...
December 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29232053/differential-diagnosis-of-otitis-media-with-effusion-using-label-free-raman-spectroscopy-a-pilot-study
#4
Rishikesh Pandey, Chi Zhang, Jeon Woong Kang, Parind M Desai, Ramachandra Rao Dasari, Ishan Barman, Tulio A Valdez
Otitis media with effusion (OME) is an important and common condition affecting hearing in pediatric patients characterized by the presence of fluid in the middle ear space. The fluid is normally described as serous or mucoid based on differences in the fluid viscosity. The differential diagnosis of two OMEs namely serous and mucoid is of significant clinical value because while the former is self-limiting, surgical procedure is commonly required for the latter. However, accurate identification of fluid types remains a challenging target unattainable with current clinical modalities due to unavailability of non-perturbative molecular tools...
December 12, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29231979/otitis-media-with-effusion-in-the-boxer-a-report-of-seven-cases
#5
S Paterson
The aim of this study was to describe otitis media with effusion in seven boxers. All dogs presented with a range of clinical signs, which included head shaking, neurological dysfunction, pain on opening of the mouth and reduction in hearing ability. Otitis media was confirmed under general anaesthesia in each case by video-otoscopic identification of a bulging pars tensa and subsequent myringotomy, which revealed a tenacious mucus plug within the middle ear. Brainstem auditory evoked response thresholds were elevated in all affected ears...
December 12, 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29230970/the-dnabii-family-of-proteins-is-comprised-of-the-only-nucleoid-associated-proteins-required-for-nontypeable-haemophilus-influenzae-biofilm-structure
#6
Aishwarya Devaraj, John Buzzo, Christopher J Rocco, Lauren O Bakaletz, Steven D Goodman
Biofilms play a central role in the pathobiology of otitis media (OM), bronchitis, sinusitis, conjunctivitis, and pneumonia caused by nontypeable Haemophilus influenzae (NTHI). Our previous studies show that extracellular DNA (eDNA) and DNABII proteins are essential components of biofilms formed by NTHI. The DNABII protein family includes integration host factor (IHF) and the histone-like protein HU and plays a central role in NTHI biofilm structural integrity. We demonstrated that immunological targeting of these proteins during NTHI-induced experimental OM in a chinchilla model caused rapid clearance of biofilms from the middle ear...
December 12, 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/29227464/antibiotic-resistance-of-potential-otopathogens-isolated-from-nasopharyngeal-flora-of-children-with-acute-otitis-media-before-during-and-after-pneumococcal-conjugate-vaccines-implementation
#7
Alexis Rybak, Corinne Levy, Stéphane Bonacorsi, Stéphane Béchet, François Vié le Sage, Annie Elbez, Emmanuelle Varon, Robert Cohen
BACKGROUNDL: To re-evaluate antibiotic strategies for acute otitis media (AOM) in young children, we analyzed the trends of nasopharyngeal carriage and antibiotic resistance of Streptococcus pneumoniae (Sp), Haemophilus influenzae (Hi) and Moraxella catarrhalis (Mc) isolated from young children with AOM during a 16-year period. METHODS: This cross-sectional study analyzed from 2001 to 2016, the nasopharyngeal carriage of Sp, Hi and Mc of young children with AOM...
December 8, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29227448/cochlear-implantation-in-chronic-otitis-media-with-cholesteatoma-and-open-cavities-long-term-surgical-outcomes
#8
Ashish Vashishth, Andrea Fulcheri, Sampath Chandra Prasad, Manjunath Dandinarasaiah, Antonio Caruso, Mario Sanna
OBJECTIVES: To evaluate the long-term surgical outcomes of cochlear implantation (CI) in chronic otitis media (COM) with cholesteatoma and open cavities using subtotal petrosectomy (STP). To review device explantation (DE) patients and reimplantation considerations. STUDY DESIGN: Retrospective review. SETTING: Otology and skull base center. PATIENTS AND METHODS: Charts of 35 patients (36 ears) with COM with cholesteatoma, including open cavities, who underwent CI were reviewed for surgical outcomes and DE...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29225513/an-abrupt-bleeding-of-the-anteriorly-displaced-sigmoid-sinus-a-rare-complication-of-myringoplasty
#9
Sarah Zaher Addeen, Mohammad Al-Mohammad
Background: The location of the sigmoid sinus within the mastoid cavity is quite variable. An anteriorly- displaced vertical segment of the sigmoid sinus constitutes an uncommon but dangerous anatomical variation that surgeons rarely encounter during surgery. In this variation, the sigmoid sinus lays underneath a very thin bony flap, which makes it easily damaged. Thus, an abrupt fatal bleeding might occur. Despite the many hypotheses about its origin (Chronic otitis media, hypopneumatization, etc...
2017: BMC Ear, Nose, and Throat Disorders
https://www.readbyqxmd.com/read/29224773/parental-knowledge-and-attitudes-to-childhood-hearing-loss-and-hearing-services-in-the-solomon-islands
#10
Annette Kaspar, Obiga Newton, Joseph Kei, Carlie Driscoll, De Wet Swanepoel, Helen Goulios
OBJECTIVE: An understanding of parental knowledge and attitudes towards childhood hearing loss is essential to the successful implementation of audiology services. The present study aimed to investigate parental knowledge and attitudes among parents in the Solomon Islands. METHODS AND MATERIALS: A total of 100 mothers and 50 fathers were administered a questionnaire via semi-structured interviews. RESULTS: Highest parental awareness of aetiology of childhood hearing loss was noted for otitis media (94%), noise exposure (87...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224767/lugol-s-solution-eradicates-staphylococcus-aureus-biofilm-in%C3%A2-vitro
#11
Torstein Grønseth, Lene K Vestby, Live L Nesse, Even Thoen, Olivier Habimana, Magnus von Unge, Juha T Silvola
OBJECTIVES: The aim of the study was to evaluate the antibacterial efficacy of Lugol's solution, acetic acid, and boric acid against Staphylococcus aureus biofilm. METHODS: The efficacy of Lugol's solution 1%, 0.1%, and 0.05%, acetic acid 5% or boric acid 4.7% for treatment of Staphylococcus aureus biofilm in vitro was tested using 30 clinical strains. Susceptibility in the planktonic state was assessed by disk diffusion test. Antiseptic effect on bacteria in biofilm was evaluated by using a Biofilm-oriented antiseptic test (BOAT) based on metabolic activity, a biofilm bactericidal test based on culturing of surviving bacteria and confocal laser scanning microscopy combined with LIVE/DEAD staining...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224765/pre-and-post-operative-application-of-acoustic-rhinometry-in-children-with-otitis-media-with-effusion-and-with-or-without-adenoid-hypertrophy-a-retrospective-analysis
#12
Dan Lai, Gang Qin, Junmei Pu, Lu Liu, Yiying Yang
BACKGROUND: There is no standardized scheme for preoperative evaluation of adenoid hypertrophy or a consensus on surgical indications for adenoidectomy in children with otitis media with effusion (OME), especially for young children intolerant to nasal endoscopic assessment. The aim of this study was to evaluate the efficacy and reliability of acoustic rhinometry (AR) in evaluating benefits from adenoidectomy in children with OME. METHOD: Children with OME who were scheduled for surgical intervention were reviewed and AR tests performed preoperatively and postoperatively...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224762/outcomes-of-tympanoplasty-in-children-with-down-syndrome
#13
Saied Ghadersohi, Jonathan B Ida, Bharat Bhushan, Kathleen R Billings
INTRODUCTION: The prevalence of chronic otitis media with effusion (COME), and Eustachian tube dysfunction (ETD) is high in Down syndrome (DS) patients. This often necessitates multiple tympanostomy tube (TT) placements resulting in a higher rate of persistent tympanic membrane (TM) perforation requiring tympanoplasty for repair. OBJECTIVES: To assess risk factors for persistent perforation and outcomes of tympanoplasty in DS patients. METHODS: Retrospective case series of 91 ears in 69 DS patients with TM perforations, who were either observed or underwent tympanoplasty...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224752/incidence-and-factors-associated-with-revision-adenoidectomy-a-retrospective-study
#14
James Johnston, Murali Mahadevan, Richard G Douglas
INTRODUCTION: Adenoidectomy is one of the most commonly performed pediatric operations worldwide. There are a proportion of children who require revision adenoidectomy. Yet there is little in the literature about the incidence, associated factors and etiology of adenoidal regrowth. The aim of this retrospective cohort study was to determine incidence and factors associated with revision adenoidectomy. METHODS: An extraction of all hospital morbidity records belonging to patients under the age of 18 years who underwent one or more adenoidectomy procedures (with or without tonsillectomy) between January 1, 2000 and June 2016 at a tertiary care children's hospital was performed...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29223643/povidone-iodine-soaked-gelfoam-for-the-treatment-of-recalcitrant-otomycosis%C3%A2-%C3%A2-our-experiences-at-a-tertiary-care-teaching-hospital-of-eastern-india
#15
S K Swain, I C Behera, M C Sahu, A Das
INTRODUCTION: Otomycosis is a common clinical condition seen in outpatient department of otorhinolaryngology. The treatment of the otomycosis is also very simple. However, sometime it is difficult to treat otomycosis along with mastoid cavity, chronic suppurative otitis media, immunocompromised patient, etc. with conventional treatment, called recalcitrant otomycosis. Here, we describe a technique of treatment for recalcitrant otomycosis. MATERIALS AND METHODS: This is a prospective observational study/clinical trial carried out on 44 patients of recalcitrant otomycosis...
December 6, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29217752/mapping-the-distribution-of-stem-progenitor-cells-across-the-middle-ear-during-homeostasis-and-inflammation
#16
Abigail S Tucker, Carlene J Dyer, Juan M Fons Romero, Tathyane H N Teshima, Jennifer C Fuchs, Hannah Thompson
The middle ear epithelium is derived from neural crest and endoderm, which line distinct regions of the middle ear cavity. Here we investigate the distribution of putative stem cell markers in the middle ear combined with an analysis of the location of label retaining cells (LRCs) to create a map of the middle ear mucosa. We show that proliferating cells and LRCs were associated with specific regions of the ear epithelium, concentrated in the hypotympanum at the base of the auditory bulla and around the ear drum...
December 7, 2017: Development
https://www.readbyqxmd.com/read/29217599/ers-statement-on-obstructive-sleep-disordered-breathing-in-1-to-23-month-old-children
#17
Athanasios G Kaditis, Maria Luz Alonso Alvarez, An Boudewyns, Francois Abel, Emmanouel I Alexopoulos, Refika Ersu, Koen Joosten, Helena Larramona, Silvia Miano, Indra Narang, Hui-Leng Tan, Ha Trang, Marina Tsaoussoglou, Nele Vandenbussche, Maria Pia Villa, Dick Van Waardenburg, Silke Weber, Stijn Verhulst
The present statement was produced by a European Respiratory Society Task Force to summarise the evidence and current practice on the diagnosis and management of obstructive sleep disordered breathing (SDB) in children aged 1-23 months. A systematic literature search was completed and 159 articles were summarised to answer clinically relevant questions. SDB is suspected when symptoms or abnormalities related to upper airway obstruction are identified. Morbidity (pulmonary hypertension, growth delay, behavioural problems) and coexisting conditions (feeding difficulties, recurrent otitis media) may be present...
December 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29213272/host-responses-to-malassezia-spp-in-the-mammalian-skin
#18
REVIEW
Florian Sparber, Salomé LeibundGut-Landmann
The skin of mammalian organisms is home for a myriad of microbes. Many of these commensals are thought to have beneficial effects on the host by critically contributing to immune homeostasis. Consequently, dysbiosis can have detrimental effects for the host that may manifest with inflammatory diseases at the barrier tissue. Besides bacteria, fungi make an important contribution to the microbiota and among these, the yeast Malassezia widely dominates in most areas of the skin in healthy individuals. There is accumulating evidence that Malassezia spp...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29209853/3d-endoscopic-ear-surgery-a-clinical-pilot-study
#19
Daniele Bernardeschi, Ghizlene Lahlou, Daniele De Seta, Francesca Yoshie Russo, Isabelle Mosnier, Olivier Sterkers
OBJECTIVE: To evaluate the feasibility and efficacy of a new high-resolution 3D endoscope in endoscopic ear and lateral skull base surgery. METHODS: Eight patients, five women and three men, were included in this clinical pilot prospective study. Their age was 38 ± 17.3 years (mean ± SD, range 17-54 years). The right side was involved in five cases, and the left side in three cases. There were three cases of chronic otitis, one case of cholesteatoma of the external auditory canal, one case of otosclerosis, one case of cochlear implant surgery, and two cases of stage 2 vestibular schwannoma operated on with a retrosigmoid approach to preserve hearing...
December 5, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29209506/border-terriers-under-primary-veterinary-care-in-england-demography-and-disorders
#20
Dan G O'Neill, Elisabeth C Darwent, David B Church, Dave C Brodbelt
Background: The Border Terrier is a working terrier type that is generally considered to be a relatively healthy and hardy breed. This study aimed to characterise the demography and common disorders of Border Terriers receiving veterinary care in England using de-identified electronic patient record data within the VetCompass™ Programme. Results: Annual birth proportion for Border Terriers showed a decreasing trend from 1.46% in 2005 to 0.78% in 2014. The median adult bodyweight for males (10...
2017: Canine Genetics and Epidemiology
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