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Elina Seppälä, Saara Sillanpää, Noora Nurminen, Heini Huhtala, Jorma Toppari, Jorma Ilonen, Riitta Veijola, Mikael Knip, Markku Sipilä, Jussi Laranne, Sami Oikarinen, Heikki Hyöty
BACKGROUND: Human enteroviruses (HEVs) and rhinoviruses (HRVs) have been linked to acute otitis media (AOM). OBJECTIVES: The present study evaluates the aforementioned association in a birth cohort setting. STUDY DESIGN: The cohort included 286 healthy infants (191 boys) followed from birth up to the age of 2 years in the Type 1 Diabetes Prediction and Prevention study in Finland. Stool samples were collected monthly and analyzed for the presence of HRV and HEV RNA using RT-PCR...
October 20, 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
Gen Kano, Hisashi Tsujii, Kazuhiko Takeuchi, Kaname Nakatani, Makoto Ikejiri, Satoru Ogawa, Hisami Kubo, Mizuho Nagao, Takao Fujisawa
Primary ciliary dyskinesia (PCD) is a rare genetic disorder caused by structural and/or functional impairment of cilia throughout the whole body. Early diagnosis of PCD is important for the prevention of long‑term sequelae, however early diagnosis is a challenge due to the phenotypic heterogeneity of PCD. In the current study, the patient with PCD was diagnosed at nine years old following several efforts to control intractable airway symptoms. The patient experienced a chronic productive cough beginning in early childhood and had multiple episodes of pneumonia and otitis media with effusion and sinusitis...
October 21, 2016: Molecular Medicine Reports
Francisco Rosa, Ana Silva, Cláudia Reis, Miguel Coutinho, Jorge Oliveira, Cecília Almeida E Sousa
OBJECTIVES: The aim of this study is to describe the experience of a tertiary referral centre in Portugal, of the placement of BAHA in children. METHODS: The authors performed a retrospective analysis of all children for whom hearing rehabilitation with BAHA was indicated at a central hospital, between January 2003 and December 2014. RESULTS: 53 children were included. The most common indications for placement of BAHA were external and middle ear malformations (n=34, 64%) and chronic otitis media with difficult to control otorrhea (n=9, 17%)...
October 21, 2016: Acta Otorrinolaringológica Española
Adam L Hersh, Katherine E Fleming-Dutra, Daniel J Shapiro, David Y Hyun, Lauri A Hicks
No abstract text is available yet for this article.
October 24, 2016: JAMA Internal Medicine
M P A Clark, B D Westerberg, J E Mitchell
OBJECTIVE: Chronic suppurative otitis media is a neglected condition affecting up to 330 million people worldwide, with the burden of the disease in impoverished countries. The need for non-governmental organisations to hardwire training into their programmes has been highlighted. An ear surgery simulator appropriate for training in resource-poor settings was developed, and its effectiveness in facilitating the acquisition of headlight and microsurgical skills necessary to safely perform procedures via the ear canal was investigated...
October 2016: Journal of Laryngology and Otology
Marrit N Habets, Saskia van Selm, Fred J van Opzeeland, Elles Simonetti, Peter W M Hermans, Marien I de Jonge, Dimitri A Diavatopoulos
Widespread vaccination against Streptococcus pneumoniae (the pneumococcus) has significantly reduced pneumococcal disease caused by vaccine serotypes. Despite vaccination, overall pneumococcal colonization rates in children have not reduced and otitis media (OM) by non-vaccine serotypes remains one of the most common childhood infections. Pneumococcal surface protein A (PspA) has been shown to be a promising protein antigen to induce broad protection against pneumococcal colonization. However, its ability to protect against OM remains unclear...
October 19, 2016: Vaccine
(no author information available yet)
No abstract text is available yet for this article.
October 22, 2016: Veterinary Record
Elisabeth Sterrer, Franz Windisch, Kurt Frey, Klaus Rettensteiner, Benjamin Loader
BACKGROUND: Middle ear adenoma with neuroendocrine differentiation (MEA-ND), also known as carcinoid tumor of the middle ear, is an extremely rare neoplasm, especially when located within the tympanic cavity. To the best of our knowledge, this represents the first pediatric case of a MEA-ND described in Europe. Excluding the present case, only three other pediatric cases of this disease have been published globally. CASE REPORT: We report on a 15-year-old female patient who presented with conductive hearing loss of the right ear...
October 19, 2016: Wiener Klinische Wochenschrift
Andrzej Misiak
Granuloma on tympanic membrane is a rare complication after ventilation drainage of tympanic cavity. The paper presents a case of a child for chronic otitis media with effusion with ventilation drainage of the right tympanic cavity, retained for 24 months, and granuloma on tympanic membrane growing all over the ventilation drain, imitating acute inflammation, causing conductive hearing loss. The patient was treated with the vent tube removal together with granulation inflammatory. Spontaneous healing of the perforation of the tympanic membrane and improve hearing were obtained after a four-month follow-up...
October 19, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Darja Kušar, Karin Šrimpf, Petra Isaković, Lina Kalšek, Javid Hosseini, Irena Zdovc, Tina Kotnik, Modest Vengušt, Gabrijela Tavčar-Kalcher
BACKGROUND: Bacterial intercellular communication, called quorum sensing, takes place via the production and collective response to signal molecules. In Gram-negative bacteria, like Pseudomonas aeruginosa, these signaling molecules are N-acylhomoserine lactones (AHLs). P. aeruginosa is a common cause of inflammation of the ear canal (otitis externa) in dogs. It employs quorum sensing to coordinate the expression of host tissue-damaging factors, which are largely responsible for its virulence...
October 18, 2016: BMC Veterinary Research
Morgane Choquet, Emilie Pluquet, Sandrine Castelain, Raphaël Guihéneuf, Véronique Decroix
BACKGROUND: Aggregatibacter aphrophilus, a commensal of the oro-pharyngeal flora and member of the HACEK group of organisms, is an uncommonly encountered clinical pathogen. It has already been described as the causative agent of brain abscesses, empyema, meningitis, sinusitis, otitis media, bacteriemia, pneumonia, osteomyelitis, peritonitis, endocarditis and wound infections. Herein we report the first case of bartholinitis due to A. aphrophilus. CASE PRESENTATION: A 33-year-old woman was admitted for a 3-day genital pain without fever and urinary functional signs...
October 18, 2016: BMC Infectious Diseases
Miki Ikehata, Shigeto Ohta, Yasuo Mishiro, Hirokazu Katsura, Shinya Miuchi, Kenzo Tsuzuki, Masafumi Sakagami
OBJECTIVE: The eustachian tube (ET) has two important functions, ventilation and clearance of the middle ear. We evaluated the ET ventilator function by the sonotubometry and the inflation-deflation test that are widely used today, and the ET clearance function by the saccharin test. Results of both tests were compared with surgical outcomes, and assessed which test was more closely related to the surgical outcomes. STUDY DESIGN: Prospective case series. SETTING: A single university hospital...
October 12, 2016: Otology & Neurotology
Sophie C H Wen, Damien Phillips, Amanda Gwee
No abstract text is available yet for this article.
November 2016: Pediatric Infectious Disease Journal
Hyun-Min Lee, Keun-Ik Yi, Jae-Hoon Jung, Il-Woo Lee
We report an extremely rare case of hearing aid silicone impression material as a foreign body in the middle ear. Symptoms of the patient were otorrhea and vertigo after taking of a mold impression on his only hearing ear, and the symptoms mimicked chronic otitis media. A temporal bone CT scan revealed foreign body material in the middle ear and Eustachian tube. An intact canal wall mastoidectomy with a facial recess approach and type IV tympanoplasty was performed to remove the silicone impression material...
September 28, 2016: American Journal of Otolaryngology
Meirav Sokolov, Ohad Hilly, David Ulanovski, Yotam Shkedy, Joseph Attias, Eyal Raveh
OBJECTIVES: Evaluate the intra- and postoperative effects of untreated otitis media with effusion (OME) in cochlear implant (CI) patients, and to assess the role of ventilation tube (VT) introduction before implantation. STUDY DESIGN: A retrospective chart review. SETTING: Tertiary referral center. PATIENTS: CI patients, aged 10 years or younger, implanted during 2009 to 2013. INTERVENTIONS: Cases were divided into three groups: 1) normal aerated middle ear before CI, 2) OME treated with VT, and 3) untreated OME...
September 30, 2016: Otology & Neurotology
Yuka Morita, Kuniyuki Takahashi, Shuji Izumi, Yamato Kubota, Shinsuke Ohshima, Arata Horii
OBJECTIVE: Otitis media (OM) with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (OMAAV) is a novel concept of ear disease that is characterized by progressive mixed or sensorineural hearing loss with occasional systemic involvement. Considering the accumulating knowledge about the characteristics of and treatment for auditory dysfunction in OMAAV, the objective of this study was to investigate the vestibular function and symptoms of patients with OMAAV. STUDY DESIGN: Retrospective chart review...
September 30, 2016: Otology & Neurotology
Hong-Bo Li, Xu-Hui Tai, Yue-Hong Sang, Jian-Ping Jia, Zhen-Ming Xu, Xiao-Feng Cui, Song Dai
BACKGROUND: Nutrients related to serum vitamin D level were previously shown to be significantly associated with the risk of many chronic diseases. This study aimed to assess potential relationships between serum vitamin D level and otitis media (OM) risk. METHODS: PubMed, EMBASE, and Cochrane Library databases were searched till Aug 18, 2015 for studies of quantitative OM risk estimates in relation to serum vitamin D level. The odds ratio and weighted mean difference, with 95% confidence intervals (CIs), were used to measure the relationship between serum vitamin D level and OM risk...
October 2016: Medicine (Baltimore)
E Carmel, J H Curotta, A T Cheng
OBJECTIVE: To evaluate the effect of pre- and post-admission antibiotic treatment in paediatric acute mastoiditis. DESIGN: Retrospective study. METHOD: Eighty-eight children with acute mastoiditis, from 2003 to 2012, were studied to investigate the effect of antibiotic therapy on short and long-term sequelae. RESULTS: The median period of antibiotic therapy immediately following hospital discharge was 10 days (range, 5-49 days; standard deviation = 7...
October 17, 2016: Journal of Laryngology and Otology
S Paterson
Topical otic products form an integral part of the overall management of otitis externa. With an ever increasing array of ear drops and cleaners to choose from, appropriate selection of therapy can be difficult. The investigation of all cases of otitis externa should consider primary and secondary causes and predisposing and perpetuating factors. This article considers topical therapy under these same broad headings and discusses, through literature review, the various properties of the components of the ear cleaning solutions and drops...
October 16, 2016: Journal of Small Animal Practice
Stefan Flasche, Noga Givon-Lavi, Ron Dagan
Pneumococcal conjugate vaccines (PCVs) have substantially reduced the burden of pneumococcal disease, including the incidence of otitis media (OM). However, in most countries, no surveillance exists to monitor the change in pneumococcal OM incidence after the introduction of PCVs. We explored whether measuring pneumococcal carriage was a useful surrogate for monitoring postvaccination changes in the incidence of pneumococcal OM. The 7-valent PCV was introduced to Israel's national immunization program in July 2009 and gradually replaced by the 13-valent PCV starting in November 2010...
October 15, 2016: American Journal of Epidemiology
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