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https://www.readbyqxmd.com/read/29457208/children-deserve-smoke-free-world
#1
REVIEW
R Remesh Kumar, P R Jayakumar, R Krishna Mohan
Tobacco smoke, active or passive exposure was the major cause of preventable morbidity and mortality in the world during twentieth century and will continue to be the same in the twenty-first century also if the current trends continue. Both active and passive smoking are having significance in relation to child health. Exposure starts antenatally from placenta to the fetus and later phases through passive exposure to experimental and regular smoking and ultimately addiction and habitual smoking. Evidences are in favour of causal relationship with intrauterine growth restriction, sudden infant death syndrome, decreased pulmonary function, increased risk for respiratory tract infection, otitis media, wheeze, asthma, neurobehavioral disorders, cleft palate and triggering pathogenesis of fetal and childhood onset of adult diseases, especially pulmonary and cardio vascular diseases...
February 19, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29456948/is-routine-use-of-high-resolution-computerized-tomography-of-temporal-bone-in-patients-of-atticoantral-chronic-suppurative-otitis-media-without-intracranial-complications-justified
#2
Meeta Bathla, Hiren Doshi, Atul Kansara
Role of high resolution computerized tomography (HRCT) of temporal bone is established in cases of atticoantral chronic suppurative otitis media (CSOM) with intracranial complications. Routine use of HRCT in management of patients of atticoantral CSOM without intracranial complications has been an issue of debate. The aim of this study was to evaluate the routine use of HRCT of temporal bone in such cases. This study was a prospective study done at LG hospital, AMC MET Medical College, Ahmedabad to evaluate and compare the temporal bone findings in HRCT and intraoperative findings in 100 patients with atticoantral CSOM...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29456946/detection-of-epstein-barr-and-human-papilloma-viruses-in-the-middle-ear-squamous-cell-carcinoma
#3
Agus Surono, Bambang Hariwiyanto, Edhie Samodra
The uncommon ear tumor of middle ear squamous cell carcinoma (MESCC) is thought to be associated with the history of long-term chronic otitis media in the most cases. The main etiologic factor of MESCC is still unclear and may be multifactorial. Infections of Epstein-Barr virus (EBV) and Human Papillomavirus (HPV) are considered as one of the etiologic factor of MESCC. Previous studies have shown that the EBV and HPV have been detected in MESCC. Although the EBV and HPV have been implicated in human malignancies, their roles in pathogenesis of MESCC have not been elucidated...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29456937/to-evaluate-and-compare-the-result-of-ossiculoplasty-using-different-types-of-graft-materials-and-prosthesis-in-cases-of-ossicular-discontinuity-in-chronic-suppurative-otitis-media-cases
#4
Suresh Kumar, Kanak Yadav, Tarun Ojha, Abhishek Sharma, Amit Singhal, Saurabh Gakhar
Chronic suppurative otitis media, with and without cholesteatoma, frequently results in disruption of the ossicular chain. The present study was designed to compare the outcome using autologous ossicle and titanium prosthesis in two groups of suitable patients presenting with chronic suppurative otitis media for middle ear reconstructive surgeries. A prospective study done from July 2012 to December 2013, at Mahatma Gandhi Medical College and Hospital, Sitapura, Jaipur (Rajasthan). The target group included patients with chronic suppurative otitis media admitted and planned for reconstructive middle ear surgery...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29455209/obstructive-sleep-apnea-and-otolaryngologic-manifestations-in-children-with-pseudohypoparathyroidism
#5
Kathleen L Curley, Sachini Kahanda, Katia M Perez, Beth A Malow, Ashley H Shoemaker
BACKGROUND/AIMS: Pseudohypoparathyroidism (PHP) is a rare, genetic disorder. Patients with PHP may have increased prevalence of obstructive sleep apnea (OSA) but this has not been prospectively studied. METHODS: We enrolled children aged 6-18 years with PHP and matched controls. Evaluation included physical examination, medical history, and polysomnography. RESULTS: Fifteen children with PHP type 1A (PHP1A) and 15 controls completed the study...
February 16, 2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29449589/loss-of-the-homeostatic-protein-bpifa1-leads-to-exacerbation-of-otitis-media-severity-in-the-junbo-mouse-model
#6
Apoorva Mulay, Derek W Hood, Debbie Williams, Catherine Russell, Steve D M Brown, Lynne Bingle, Michael Cheeseman, Colin D Bingle
Otitis Media (OM) is characterized by epithelial abnormalities and defects in innate immunity in the middle ear (ME). Although, BPIFA1, a member of the BPI fold containing family of putative innate defence proteins is abundantly expressed by the ME epithelium and SNPs in Bpifa1 have been associated with OM susceptibility, its role in the ME is not well characterized. We investigated the role of BPIFA1 in protection of the ME and the development of OM using murine models. Loss of Bpifa1 did not lead to OM development...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29449345/antimicrobial-activity-of-a-novel-bioengineered-honey-against-non-typeable-haemophilus-influenzae-biofilms-an-in-vitro-study
#7
Rachel S Newby, Matthew Dryden, Raymond N Allan, Rami J Salib
The opportunistic pathogen non-typeable Haemophilus influenzae (NTHi) plays an important role in many chronic respiratory diseases including otitis media, chronic rhinosinusitis, cystic fibrosis and chronic obstructive pulmonary disease. Biofilm formation has been implicated in NTHi colonisation, persistence of infection and recalcitrance towards antimicrobials. There is therefore a pressing need for the development of novel treatment strategies that are effective against NTHi biofilm-associated diseases. SurgihoneyRO is a honey-based product that has been bioengineered to enable the slow release of H 2 O 2 , a reactive oxygen species to which H...
February 15, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29447898/challenges-and-outcomes-of-cholesteatoma-management-in-children-with-down-syndrome
#8
Saied Ghadersohi, Bharat Bhushan, Kathleen R Billings
INTRODUCTION: The high incidence of chronic otitis media with effusion and Eustachian tube dysfunction in children with Down syndrome (DS) may predispose them to cholesteatoma formation. Establishing the diagnosis, choosing the appropriate operative intervention, and post-operative care can be challenging. OBJECTIVE: To describe management strategies for cholesteatoma diagnosis, surgical treatment, and post-operative management in children with Down syndrome. METHODS: Retrospective case series of 14 patients (17 total ears) with Down syndrome diagnosed with cholesteatoma over a 9-year period...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447897/pattern-of-allergic-rhinitis-among-children-in-ekiti-nigeria
#9
Waheed Atilade Adegbiji, Gabriel Toye Olajide, Anthony Oyebanji Olajuyin, Shuaib Kayode Aremu, Akanbi Ganiyu Olusola
BACKGROUND: Allergic rhinitis is a chronic and recurrent nasal condition. It is often neglected in children with late presentation. This study aimed at determining the prevalence, sociodemographic features, comorbid illnesses, complications and quality of life in children with allergic rhinitis in the study institution. MATERIALS AND METHODS: This is a prospective hospital based study of children with allergic rhinitis in Ekiti state university teaching hospital, Ado Ekiti...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447882/acute-external-otitis-as-debut-of-acute-myeloid-leukemia-a-case-and-review-of-the-literature
#10
Joachim Slengerik-Hansen, Therese Ovesen
Acute leukemia is a well known childhood cancer. The relation between leukemia and otological symptoms has long been established but is highly rare as a debut symptom of leukemia. External otitis is a common condition affecting many children, and most cases are successively treated with topical medicine. Here we present a child with acute external otitis later shown to be the debut symptom of acute myeloid leukemia, to our knowledge the first specific case described. We have reviewed the literature to find red flags for suspicion of severe disease in case of acute external otitis...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447881/tympanostomy-tubes-for-serous-otitis-media-and-risk-of-recurrences
#11
Nathalie Klopp-Dutote, Catherine Kolski, Vladimir Strunski, Cyril Page
OBJECTIVES: To determine the value of tympanostomy tubes (TTs) in the management of serous otitis media (SOM) and the risk factors for SOM recurrence. METHOD: This single-centre cohort study was performed in the University hospital of Amiens, France; and concerned 215 under-12 children having undergone at least one bilateral TT (Shepard grommet-type) placements for SOM. RESULTS: The mean TT retention time was 10 months. SOM recurred in 79 children (62...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447878/risk-of-childhood-otitis-media-with-focus-on-potentially-modifiable-factors-a-danish-follow-up-cohort-study
#12
Asbjørn Kørvel-Hanquist, Anders Koch, Jørgen Lous, Sjurdur Frodi Olsen, Preben Homøe
INTRODUCTION: Otitis media is the primary cause of antibiotic prescription in children. Two-thirds of all children experience at least one episode of otitis media before the age of 7 years. The aim of this study was to characterise the attributable effect of several modifiable risk exposures on the risk of >3 episodes of otitis media at age 18 months and 7 years within a large prospective national birth cohort. METHODS: The study used the Danish National Birth Cohort comprising information about otitis media and risk exposures from more than 50,000 mother-child pairs from the period 1996-2002...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447810/no-evidence-of-cholesteatoma-in-untreated-otitis-media-with-effusion-in-children-with-primary-ciliary-dyskinesia
#13
Reshma Ghedia, Jahangir Ahmed, Annakan Navaratnam, Jonny Harcourt
INTRODUCTION: Primary Ciliary Dyskinesia (PCD) describes a group of inherited disorders that result in abnormal ciliary motion leading to mucous stasis. Clinical features include almost universally otitis media with effusion (OME), particularly in infants. PCD patients provide us with a cohort of patients with OME that is not treated with ventilatory tube (VT) insertion as these have been shown to result in frequent complications including chronic otorrhoea, early extrusion and persistent perforation without significant improvement to hearing in the long term...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447805/characterization-of-newborn-hearing-screening-failures-in-multigestational-births
#14
Jonathan Ross Mallen, Jacob B Hunter, Charles Auerbach, Leslie Wexler, Andrea Vambutas
OBJECTIVE: To define the rate and characterize the type of newborn hearing screening failures in multigestational births. METHODS: Retrospective chart review of all multigestational births that occurred in a 10-year period (2002-2012) in which at least one newborn failed newborn hearing screening at two tertiary care hospitals in the Northwell Health System. RESULTS: Out of 125,405 total births, we identified 2961 multigestational births, of which 59 (2...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447793/clinical-role-of-vitamin-d-in-prognosis-of-otitis-media-with-effusion
#15
Fatih Alper Akcan, Yusuf Dündar, Hümeyra Bayram Akcan, Ahmet Uluat, Derya Cebeci, Mehmet Ali Sungur, İlhan Ünlü
OBJECTIVE: To investigate the clinical role of Vitamin D in prognosis of Otitis media with effusion. METHODS: This prospective-controlled study was conducted at otolaryngology department in Duzce University, Turkey. The study group comprised children who were diagnosed with Otitis media with effusion between September 2016 and February 2017. Control group was conducted with children underwent circumcision or inguinal hernia repair operations that confirmed with ENT examination they do not have any sign of otitis media...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29446785/effects-of-salso-bromo-iodine-thermal-water-in-children-suffering-from-otitis-media-with-effusion-a-randomized-controlled-pilot-study
#16
I La Mantia, C Andaloro
BACKGROUND: Otitis media with effusion (OME) is an ear disorder defined by the presence of fluid in the middle ear without signs or symptoms of acute infection. The aim of this randomised and controlled pilot study was to evaluate whether the treatment with a watery salsobromo- iodine solution, administered by nasal douche, could induce ear healing better than isotonic saline in children with OME. METHODS: The study was randomized, single-blind, and controlled. Study group (40 children) was treated with salso-bromo-iodine thermal water solution and Control group (40 children) was treated with isotonic saline; both compounds were administered by nasal nebulization with Rinowash nasal douche twice/day for 10 days a month for 3 consecutive months...
January 2018: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29445883/neurological-complications-of-acute-and-chronic-otitis-media
#17
REVIEW
Michael J Hutz, Dennis M Moore, Andrew J Hotaling
PURPOSE OF REVIEW: The aim of this study is to discuss the symptoms, diagnosis, and management of the neurologic complications of acute and chronic otitis media. RECENT FINDINGS: Antibiotic therapy has greatly reduced the frequency of complications of otitis media. However, it is of vital importance to remain aware of the possible development of neurologic complications. There is a trend toward less severe presenting symptoms including otorrhea, headache, nausea, and fever, with altered mental status and focal neurologic deficits presenting later...
February 14, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29444837/whole-genome-sequence-analysis-of-streptococcus-pneumoniae-strains-that-cause-hospital-acquired-pneumonia-infections
#18
Bin Chang, Masatomo Morita, Ken-Ichi Lee, Makoto Ohnishi
Streptococcus pneumoniae colonizes the nasopharyngeal mucus in healthy individuals and can cause otitis media, pneumonia, and invasive pneumococcal diseases. In this study, we analyzed the S. pneumoniae strains that caused 19 pneumonia episodes in long-term inpatients with severe underlying disease in a hospital during a period of 14 months (from January 2014 to February 2015). Serotyping and whole genome sequencing analyses revealed that 18 of the 19 pneumonia cases were caused by S. pneumoniae strains belonging to 3 genetically distinct groups: clonal complex (CC) 9999, sequence type (ST) 282, and ST166...
February 14, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29440126/adolescent-with-painful-vesicular-otitis-and-vertigo
#19
Ester Conversano, Giorgio Cozzi, Federico Poropat, Alberto Di Mascio, Simona Salis, Domenico Leonardo Grasso, Egidio Barbi
No abstract text is available yet for this article.
February 9, 2018: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/29433161/the-allele-2-of-the-vntr-polymorphism-in-the-gene-that-encodes-a-natural-inhibitor-of-il-1%C3%AE-il-1ra-is-favorably-associated-with-chronic-otitis-media
#20
Maja Živković, Ivana Kolić, Snežana Jesić, Ana Jotić, Aleksandra Stanković
Objectives: Chronic otitis media (COM) is followed by irreversible tissue damage and destruction of the middle ear structures, with the possibility of complications under the maintenance of inflammation. Inflammatory mediators such as cytokines play a crucial role in the initial stage of inflammation. The aim of this study was to evaluate the association of the polymorphisms in two innate immunity/inflammation cascade genes from interleukin-1 (IL-1) gene cluster with COM with regard to cholesteatoma...
February 14, 2018: Clinical and Experimental Otorhinolaryngology
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