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https://www.readbyqxmd.com/read/29475209/perceptually-regulated-exercise-test-allows-determination-of-v%C3%AB-o2max-and-ventilatory-threshold-but-not-respiratory-compensation-point-in-trained-runners
#1
Perrine Truong, Gregoire P Millet, Boris Gojanovic
This study aimed to investigate the differences in maximal oxygen uptake (V̇O2max ) and submaximal thresholds between a standard graded exercise test (GXT) and a perceptually regulated graded exercise test (PRGXT) in trained runners. Eleven well-trained middle- to long-distance runners performed both tests in a randomized order. PRGXT used incremental "clamps" of rating of perceived exertion (RPE) over 10×1-min stages on an automated treadmill equipped with a sonar sensor allowing them to change their running speed instantly and in a natural way...
February 23, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29475186/an-optofluidic-metasurface-for-lateral-flow-through-detection-of-breast-cancer-biomarker
#2
Yifei Wang, Md Azahar Ali, Edmond K C Chow, Liang Dong, Meng Lu
The rapid growth of point-of-care tests demands for biosensors with high sensitivity and small size. This paper demonstrates an optofluidic metasurface that combines silicon-on-insulator (SOI) nanophotonics and nanofluidics to realize a high-performance, lateral flow-through biosensor. The metasurface is made of a periodic array of silicon nanoposts on an SOI substrate, and functionalized with specific receptor molecules. Bonding of a polydimethylsiloxane slab directly onto the surface results in an ultracompact biosensor, where analyte solutions are restricted to flow only in the space between the nanoposts...
February 17, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29474573/i-clamp-phenoxazine-for-the-fine-tuning-of-dna-i-motif-stability
#3
Vladimir B Tsvetkov, Timofei S Zatsepin, Evgeny S Belyaev, Yury I Kostyukevich, George V Shpakovski, Victor V Podgorsky, Galina E Pozmogova, Anna M Varizhuk, Andrey V Aralov
Non-canonical DNA structures are widely used for regulation of gene expression, in DNA nanotechnology and for the development of new DNA-based sensors. I-motifs (iMs) are two intercalated parallel duplexes that are held together by hemiprotonated C-C base pairs. Previously, iMs were used as an accurate sensor for intracellular pH measurements. However, iM stability is moderate, which in turn limits its in vivo applications. Here, we report the rational design of a new substituted phenoxazine 2'-deoxynucleotide (i-clamp) for iM stabilization...
February 21, 2018: Nucleic Acids Research
https://www.readbyqxmd.com/read/29474447/contribution-of-s4-segments-and-s4-s5-linkers-to-the-low-voltage-activation-properties-of-t-type-cav3-3-channels
#4
Ana Laura Sanchez-Sandoval, Zazil Herrera Carrillo, Clara Estela Díaz Velásquez, Dulce María Delgadillo, Heriberto Manuel Rivera, Juan Carlos Gomora
Voltage-gated calcium channels contain four highly conserved transmembrane helices known as S4 segments that exhibit a positively charged residue every third position, and play the role of voltage sensing. Nonetheless, the activation range between high-voltage (HVA) and low-voltage (LVA) activated calcium channels is around 30-40 mV apart, despite the high level of amino acid similarity within their S4 segments. To investigate the contribution of S4 voltage sensors for the low-voltage activation characteristics of CaV3...
2018: PloS One
https://www.readbyqxmd.com/read/29474387/mobile-phones-as-monitors-of-personal-exposure-to-air-pollution-is-this-the-future
#5
Mawutorli Nyarku, Mandana Mazaheri, Rohan Jayaratne, Matthew Dunbabin, Md Mahmudur Rahman, Erik Uhde, Lidia Morawska
Mobile phones have a large spectrum of applications, aiding in risk prevention and improving health and wellbeing of their owners. So far, however, they have not been used for direct assessment of personal exposure to air pollution. In this study, we comprehensively evaluated the first, and the only available, mobile phone-BROAD Life-equipped with air pollution sensors (PM2.5 and VOC), to answer the question whether this technology is a viable option in the quest of reducing the burden of disease to air pollution...
2018: PloS One
https://www.readbyqxmd.com/read/29474059/a-halotag-based-multi-color-fluorogenic-sensor-visualizes-and-quantifies-proteome-stress-in-live-cells-using-solvatochromic-and-molecular-rotor-based-fluorophores
#6
Yu Liu, Kun Miao, Yinghao Li, Matthew Fares, Shuyuan Chen, Xin Zhang
Protein homeostasis, or proteostasis, is essential for cellular fitness and viability. Many environmental factors compromise proteostasis, induce global proteome stress, and cause diseases. Proteome stress sensor is a powerful tool to dissect the mechanism of cellular stress and find therapeutics that ameliorate these diseases. In this work, we present a multi-color HaloTag-based sensor (named AgHalo) to visualize and quantify proteome stresses in live cells. The current AgHalo sensor is equipped with three fluorogenic probes that turn on fluorescence when the sensor forms either soluble oligomers or insoluble aggregates upon exposure to stress conditions, both in vitro and in cellulo...
February 23, 2018: Biochemistry
https://www.readbyqxmd.com/read/29473925/rational-design-of-3d-inverse-opal-heterogeneous-composite-microspheres-as-excellent-visible-light-induced-no-2-sensors-at-room-temperature
#7
Tianshuang Wang, Qi Yu, Sufang Zhang, Xueying Kou, Peng Sun, Geyu Lu
The lower gas sensitivity, humidity dependence of the gas sensing properties, and long recovery times of room-temperature gas sensors severely limit their applications. Herein, to address these issues, a series of 3D inverse opal (IO) In2 O3 -ZnO heterogeneous composite microspheres (HCMs) are fabricated by ultrasonic spray pyrolysis (USP) employing self-assembled sulfonated polystyrene (S-PS) spheres as a sacrificial template. The 3D IO In2 O3 -ZnO HCMs possess highly ordered 3D inverse opal structures and bimodal (meso-scale and macro-scale) pores, which can provide large accessible surface areas and rapid mass transfer, resulting in enhanced gas sensing characteristics...
February 23, 2018: Nanoscale
https://www.readbyqxmd.com/read/29473919/leader-follower-formation-control-of-uuvs-with-model-uncertainties-current-disturbances-and-unstable-communication
#8
Zheping Yan, Da Xu, Tao Chen, Wei Zhang, Yibo Liu
Unmanned underwater vehicles (UUVs) have rapidly developed as mobile sensor networks recently in the investigation, survey, and exploration of the underwater environment. The goal of this paper is to develop a practical and efficient formation control method to improve work efficiency of multi-UUV sensor networks. Distributed leader-follower formation controllers are designed based on a state feedback and consensus algorithm. Considering that each vehicle is subject to model uncertainties and current disturbances, a second-order integral UUV model with a nonlinear function is established using the state feedback linearized method under current disturbances...
February 23, 2018: Sensors
https://www.readbyqxmd.com/read/29473917/enhanced-humidity-sensitivity-with-silicon-nanopillar-array-by-uv-light
#9
Wei Li, Chao Ding, Yun Cai, Juyan Liu, Linlin Wang, Qingying Ren, Jie Xu
The sensitivity of silicon nanopillar array for relative humidity (RH) with UV illumination was investigated in this work. The silicon nanopillar array was prepared by nanosphere lithography. Electrical measurements were performed on its sensing performance with and without UV irradiation. It was found that UV light improved the humidity sensitivity with different UV light wavelengths and power. The sensor response and recovery time were reduced. Furthermore, the turn-on threshold voltage and the operating voltage both decreased...
February 23, 2018: Sensors
https://www.readbyqxmd.com/read/29473911/methionine-capped-gold-nanoclusters-as-a-fluorescence-enhanced-probe-for-cadmium-ii-sensing
#10
Yan Peng, Maomao Wang, Xiaoxia Wu, Fu Wang, Lang Liu
Gold nanoclusters (Au NCs) have been considered as novel heavy metal ions sensors due to their ultrafine size, photo-stability and excellent fluorescent properties. In this study, a green and facile method was developed for the preparation of fluorescent water-soluble gold nanoclusters with methionine as a stabilizer. The nanoclusters emit orange fluorescence with excitation/emission peaks at 420/565 nm and a quantum yield of about 1.46%. The fluorescence of the Au NCs is selectively and sensitively enhanced by addition of Cd(II) ions attributed to the Cd(II) ion-induced aggregation of nanoclusters...
February 23, 2018: Sensors
https://www.readbyqxmd.com/read/29473910/a-method-for-dynamically-selecting-the-best-frequency-hopping-technique-in-industrial-wireless-sensor-network-applications
#11
Erlantz Fernández de Gorostiza, Jorge Berzosa, Jon Mabe, Roberto Cortiñas
Industrial wireless applications often share the communication channel with other wireless technologies and communication protocols. This coexistence produces interferences and transmission errors which require appropriate mechanisms to manage retransmissions. Nevertheless, these mechanisms increase the network latency and overhead due to the retransmissions. Thus, the loss of data packets and the measures to handle them produce an undesirable drop in the QoS and hinder the overall robustness and energy efficiency of the network...
February 23, 2018: Sensors
https://www.readbyqxmd.com/read/29473877/parameter-estimation-of-the-thermal-network-model-of-a-machine-tool-spindle-by-self-made-bluetooth-temperature-sensor-module
#12
Yuan-Chieh Lo, Yuh-Chung Hu, Pei-Zen Chang
Thermal characteristic analysis is essential for machine tool spindles because sudden failures may occur due to unexpected thermal issue. This article presents a lumped-parameter Thermal Network Model (TNM) and its parameter estimation scheme, including hardware and software, in order to characterize both the steady-state and transient thermal behavior of machine tool spindles. For the hardware, the authors develop a Bluetooth Temperature Sensor Module (BTSM) which accompanying with three types of temperature-sensing probes (magnetic, screw, and probe)...
February 23, 2018: Sensors
https://www.readbyqxmd.com/read/29473867/microwave-sensors-for-breast-cancer-detection
#13
REVIEW
Lulu Wang
Breast cancer is the leading cause of death among females, early diagnostic methods with suitable treatments improve the 5-year survival rates significantly. Microwave breast imaging has been reported as the most potential to become the alternative or additional tool to the current gold standard X-ray mammography for detecting breast cancer. The microwave breast image quality is affected by the microwave sensor, sensor array, the number of sensors in the array and the size of the sensor. In fact, microwave sensor array and sensor play an important role in the microwave breast imaging system...
February 23, 2018: Sensors
https://www.readbyqxmd.com/read/29473862/using-a-second-order-sigma-delta-control-to-improve-the-performance-of-metal-oxide-gas-sensors
#14
Lukasz Kowalski, Joan Pons-Nin, Eric Navarrete, Eduard Llobet, Manuel Domínguez-Pumar
Controls of surface potential have been proposed to accelerate the time response of MOX gas sensors. These controls use temperature modulations and a feedback loop based on first-order sigma-delta modulators to keep constant the surface potential. Changes in the surrounding gases, therefore, must be compensated by average temperature produced by the control loop, which is the new output signal. The purpose of this paper is to present a second order sigma-delta control of the surface potential for gas sensors...
February 23, 2018: Sensors
https://www.readbyqxmd.com/read/29473737/optofluidic-sensor-for-inline-hemolysis-detection-on-whole-blood
#15
Chen Zhou, Mehdi Keshavarz Hedayati, Xiaolong Zhu, Frank Nielsen, Uriel Levy, Anders Kristensen
Hemolysis is the rupture of red blood cells and constitutes the most common reason for unsuitable blood samples in the clinic. To detect hemolysis, one has to separate the hemoglobin in blood plasma from that in red blood cells. However, current methods entail centrifugation for cell-plasma separation, which is complex, time-consuming, and not easy to integrate into point-of-care (PoC) systems. Here, we demonstrate an optofluidic sensor composed of nanofilters on an optical waveguide, which enables evanescent-wave absorption measurement of hemoglobin in plasma with the capability of real-time inline detection on whole blood without extra sample preparation like centrifugation...
February 23, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29473716/magneto-mechanical-surfaces-design
#16
REVIEW
Andrés C Galera, Verónica San Miguel, Juan Baselga
Magneto-mechanically active surfaces (MMAS) represent a new family of nano/micro-structured surfaces in which motion is induced by an external magnetic field. Under the name of "artificial cilia", "biomimetic cilia", "magnetic actuated patterns", "nanopillars", etc., published works in this area continue their quick growth in number. Notwithstanding their potential application in microfluidic, chemical sensors, catalytic processes and microelectronics to increase device perfomances, there is still a lot to do in the development of these materials...
February 23, 2018: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
https://www.readbyqxmd.com/read/29473416/novel-electrochemical-paper-based-immunocapture-assay-for-the-quantitative-determination-of-ethinylestradiol-in-water-samples
#17
María L Scala-Benuzzi, Julio Raba, Galo J A A Soler-Illia, Rudolf J Schneider, Germán A Messina
We report a novel and innovative electrochemical paper-based immunocapture assay (EPIA) to address the need for ultrasensitive detection of emerging pollutants without regulatory status and whose effects on environment and human health are not completely yet understood. In particular, we present the application of this system towards highly sensitive detection of the emerging pollutant ethinyl estradiol (EE2). The EPIA approach is based on the use of paper microzones modified with silica nanoparticles (SNs) and anti-EE2 specific antibodies for capture and pre-concentration of EE2 from river water samples...
February 23, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29473414/quantitative-rheometry-of-thin-soft-materials-using-the-quartz-crystal-microbalance-with-dissipation-qcm-d
#18
Kazi Sadman, Clinton G Wiener, R A Weiss, Christopher C White, Kenneth R Shull, Bryan D Vogt
In the inertial limit, the resonance frequency of the quartz crystal microbalance (QCM) is related to the coupled mass on the quartz sensor through the Sauerbrey expression that relates the mass to the change in resonance frequency. However, when the thickness of the film is sufficiently large, the relationship becomes more complicated and both the frequency and damping of the crystal resonance must be considered. In this regime, a rheological model of the material must be used to accurately extract the adhered film's thickness, shear modulus, and viscoelastic phase angle from the data...
February 23, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29473409/self-powered-temperature-mapping-sensors-based-on-thermo-magneto-electric-generator
#19
Jinsung Chun, Ravi Anant Kishore, Prashant Kumar, Min-Gyu Kang, Han Byul Kang, Mohan Sanghadasa, Shashank Priya
We demonstrate a thermo-magneto-electric generator (TMEG) based on second order phase transition of soft magnetic materials that provides promising pathway for scavenging low grade heat. It takes advantage of the cyclic magnetic forces of attraction and repulsion arising through ferromagnetic-to-paramagnetic phase transition to create mechanical vibrations which are converted into electricity through piezoelectric benders. In order to enhance the mechanical vibrations frequency and thereby output power of TMEG, we utilize the nonlinear behaviour of piezoelectric cantilevers and enhanced thermal transport through silver (Ag) nanoparticles (NPs) applied on the surface of a soft magnet...
February 23, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29473299/short-wave-infrared-sensor-by-the-photothermal-effect-of-colloidal-gold-nanorods
#20
Hengyang Xiang, Tingting Niu, Mathilde Schoenauer Sebag, Zhelu Hu, Xiangzhen Xu, Laurent Billot, Lionel Aigouy, Zhuoying Chen
Photodetection in the short-wave infrared (SWIR) spectrum is a challenging task achieved often by costly low bandgap compound semiconductors involving highly toxic elements. In this work, an alternative low-cost approach is reported for SWIR sensors that rely on the plasmonic-induced photothermal effect of solution-processed colloidal gold nanorods (Au NRs). A series of uniform solution-processed Au NRs of various aspect ratios are prepared exhibiting a strong and well-defined longitudinal localized surface plasmon resonance (L-LSPR) maximum from 900 nm to 1...
February 23, 2018: Small
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