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https://www.readbyqxmd.com/read/29232619/engineering-of-protein-nanopores-for-sequencing-chemical-or-protein-sensing-and-disease-diagnosis
#1
REVIEW
Shaoying Wang, Zhengyi Zhao, Farzin Haque, Peixuan Guo
Biological systems contain highly-ordered structures performing diverse functions. The elegant structures of biomachines have inspired the development of nanopores as single molecule sensors. Over the years, the utility of nanopores for detecting a wide variety of analytes have rapidly emerged for sensing, sequencing and diagnostic applications. Several protein channels with diverse shapes and sizes, such as motor channels from bacteriophage Phi29, SPP1, T3, and T4, as well as α-hemolysin, MspA, aerolysin, FluA, OmpF/G, CsgG, ClyA, have been continually investigated and developed as nanopores...
December 9, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/29232614/evaluation-of-carbon-nanotube-based-copper-nanoparticle-composite-for-the-efficient-detection-of-agroviruses
#2
Muhammad Ali Tahir, Sadia Z Bajwa, Shahid Mansoor, Rob W Briddon, Waheed S Khan, Brian E Scheffler, Imran Amin
We report a biosensor that combines the construction of a three-dimensional nanocomposite with electrochemical methods for the detection of viruses in plants. This is the first report, where carbon nanotubes are used as a conductive frame to anchor highly electrolytic agglomerates of copper nanoparticles to detect agroviruses. Morphological analysis of nanocomposite revealed the presence of carbon nanotubes having a diameter of 50-100nm with copper nanoparticles of 20-100nm, attached in the form of bunches...
December 5, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29232150/unusual-ferroelectricity-in-two-dimensional-perovskite-oxide-thin-films
#3
Jinlian Lu, Wei Luo, Junsheng Feng, Hongjun Xiang
Two-dimensional (2D) ferroelectricity have attracted much attention due to their applications in novel miniaturized devices such as non-volatile memories, field effect transistors and sensors. Since most of the commercial ferroelectric (FE) devices are based on ABO3 perovskite oxides, it is important to investigate the properties of 2D ferroelectricity in perovskite oxides thin films. Here, based on density functional theory (DFT) calculations, we find that there exist three kinds of in-plane ferroelectric states which originate from different microscopic mechanisms: (i) a proper FE state with the polarization along [110] due to the second-order Jahn-Teller effect related to the B ion with empty d-orbitals; (ii) a robust FE state with the polarization along [100] induced by the surface effect; (iii) a hybrid improper FE state with the polarization along [110] that is induced by the tri-linear coupling between two rotational modes and the A-site displacement...
December 12, 2017: Nano Letters
https://www.readbyqxmd.com/read/29232111/a-hand-held-optoelectronic-nose-for-the-identification-of-liquors
#4
Zheng Li, Kenneth S Suslick
Successful discrimination of 14 representative liquors (including scotch, bourbon and rye whiskies, brandy, and vodka) was achieved using a 36-element colorimetric sensor array comprising multiple classes of cross-reactive, chemically responsive inks. In combination with a palm-sized image analyzer, the sensor array permits real-time identification of liquor products based on vapor analysis within 2 min. Changes in sensor spot colors before and after exposure to the vapors of the liquors that are partially oxidized as they are pumped over the sensor array provides a unique color difference pattern for each analyte...
December 12, 2017: ACS Sensors
https://www.readbyqxmd.com/read/29231965/mapping-multi-scale-vascular-plant-richness-in-a-forest-landscape-with-integrated-lidar-and-hyperspectral-remote-sensing
#5
C R Hakkenberg, K Zhu, R K Peet, C Song
The central role of floristic diversity in maintaining habitat integrity and ecosystem function has propelled efforts to map and monitor its distribution across forest landscapes. While biodiversity studies have traditionally relied largely on ground-based observations, the immensity of the task of generating accurate, repeatable, and spatially-continuous data on biodiversity patterns at large scales has stimulated the development of remote-sensing methods for scaling up from field plot measurements. One such approach is through integrated LiDAR and hyperspectral remote-sensing...
December 12, 2017: Ecology
https://www.readbyqxmd.com/read/29231887/real-time-monitoring-in-home-based-cardiac-rehabilitation-using-wrist-worn-heart-rate-devices
#6
Javier Medina Quero, María Rosa Fernández Olmo, María Dolores Peláez Aguilera, Macarena Espinilla Estévez
Cardiac rehabilitation is a key program which significantly reduces the mortality in at-risk patients with ischemic heart disease; however, there is a lack of accessibility to these programs in health centers. To resolve this issue, home-based programs for cardiac rehabilitation have arisen as a potential solution. In this work, we present an approach based on a new generation of wrist-worn devices which have improved the quality of heart rate sensors and applications. Real-time monitoring of rehabilitation sessions based on high-quality clinical guidelines is embedded in a wearable application...
December 12, 2017: Sensors
https://www.readbyqxmd.com/read/29231879/molybdenum-dichalcogenides-for-environmental-chemical-sensing
#7
REVIEW
Dario Zappa
2D transition metal dichalcogenides are attracting a strong interest following the popularity of graphene and other carbon-based materials. In the field of chemical sensors, they offer some interesting features that could potentially overcome the limitation of graphene and metal oxides, such as the possibility of operating at room temperature. Molybdenum-based dichalcogenides in particular are among the most studied materials, thanks to their facile preparation techniques and promising performances. The present review summarizes the advances in the exploitation of these MoX₂ materials as chemical sensors for the detection of typical environmental pollutants, such as NO₂, NH₃, CO and volatile organic compounds...
December 12, 2017: Materials
https://www.readbyqxmd.com/read/29231868/a-data-driven-response-virtual-sensor-technique-with-partial-vibration-measurements-using-convolutional-neural-network
#8
Shan-Bin Sun, Yuan-Yuan He, Si-Da Zhou, Zhen-Jiang Yue
Measurement of dynamic responses plays an important role in structural health monitoring, damage detection and other fields of research. However, in aerospace engineering, the physical sensors are limited in the operational conditions of spacecraft, due to the severe environment in outer space. This paper proposes a virtual sensor model with partial vibration measurements using a convolutional neural network. The transmissibility function is employed as prior knowledge. A four-layer neural network with two convolutional layers, one fully connected layer, and an output layer is proposed as the predicting model...
December 12, 2017: Sensors
https://www.readbyqxmd.com/read/29231864/vibration-sensor-monitoring-of-nickel-titanium-alloy-turning-for-machinability-evaluation
#9
Tiziana Segreto, Alessandra Caggiano, Sara Karam, Roberto Teti
Nickel-Titanium (Ni-Ti) alloys are very difficult-to-machine materials causing notable manufacturing problems due to their unique mechanical properties, including superelasticity, high ductility, and severe strain-hardening. In this framework, the aim of this paper is to assess the machinability of Ni-Ti alloys with reference to turning processes in order to realize a reliable and robust in-process identification of machinability conditions. An on-line sensor monitoring procedure based on the acquisition of vibration signals was implemented during the experimental turning tests...
December 12, 2017: Sensors
https://www.readbyqxmd.com/read/29231848/on-line-corrosion-monitoring-of-plate-structures-based-on-guided-wave-tomography-using-piezoelectric-sensors
#10
Jing Rao, Madis Ratassepp, Danylo Lisevych, Mahadhir Hamzah Caffoor, Zheng Fan
Corrosion is a major safety and economic concern to various industries. In this paper, a novel ultrasonic guided wave tomography (GWT) system based on self-designed piezoelectric sensors is presented for on-line corrosion monitoring of large plate-like structures. Accurate thickness reconstruction of corrosion damages is achieved by using the dispersive regimes of selected guided waves and a reconstruction algorithm based on full waveform inversion (FWI). The system makes use of an array of miniaturised piezoelectric transducers that are capable of exciting and receiving highly dispersive A0 Lamb wave mode at low frequencies...
December 12, 2017: Sensors
https://www.readbyqxmd.com/read/29231782/akin10-activity-as-a-cellular-link-between-metabolism-and-circadian-clock-entrainment-in-arabidopsis-thaliana
#11
Alfredo Sánchez-Villarreal, Amanda M Davis, Seth J Davis
AKIN10, the catalytic subunit of the Snf1 (sucrose non-fermenting 1)-related kinase 1 (SnRK1) complex, acts as an energy sensor in plants. We showed that AKIN10-induced expression affects the pace of the circadian clock and particularly the phase of expression of GIGANTEA (GI). The AKIN10 effect on period length required TIME FOR COFFEE (TIC), a circadian-clock component with developmental and metabolic roles. Here we expand on the possible interactions between AKIN10, whose activity is involved in transcriptional reprogramming, and clock elements GI and TIC...
December 12, 2017: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/29231714/acid-induced-multicolor-fluorescence-of-pyridazine-derivative
#12
Mengwei Li, Yuan Yuan, Yulan Chen
Smart luminescent materials that are responsive to external stimuli have received considerable attention. Here we report a new D-A type 1,2-pyridiazine derivative (TPP) exhibiting turn-on fluorescence upon acid both in solution and in solid state. The protonation of the 1,2-pyridiazine ring caused a variation in the emission colors of the acidification species from blue (406 nm) to orange-red (630 nm) with a huge Δλem (224 nm). As a result, a synthetic rainbow of emission in solution could be achieved from one single molecule, and white photoluminescence was readily tuned by controlled protonation...
December 12, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29231710/recent-advances-in-the-development-of-chromophore-based-chemosensors-for-nerve-agents-and-phosgene
#13
Liyan Chen, Di Wu, Juyoung Yoon
The extreme toxicity and ready accessibility of nerve agents and phosgene has caused an increase in the demand to develop effective systems for the detection of these substances. Among the traditional platforms utilized for this purpose, chemosensors including surface acoustic wave (SAW) sensors, enzymes, carbon nanotubes, nanoparticles and chromophore based sensors have attractive increasing attentions. In this review, we describe in a comprehensive manner recent progress that has been made on the development of chromophore-based chemosensors for detecting nerve agents (mimic) and phosgene...
December 12, 2017: ACS Sensors
https://www.readbyqxmd.com/read/29231251/mechanoactivation-of-the-angiotensin-ii-type-1-receptor-induces-%C3%AE-arrestin-biased-signaling-through-g%C3%AE-i-coupling
#14
Jialu Wang, Kenji Hanada, Clarice Gareri, Howard A Rockman
Ligand activation of the angiotensin II type 1 receptor (AT1R), a member of the G protein-coupled receptor (GPCR) family, stimulates intracellular signaling to mediate a variety of physiological responses. The AT1R is also known to be a mechanical sensor. When activated by mechanical stretch, the AT1R can signal via the multifunctional adaptor protein β-arrestin, rather than through classical heterotrimeric G protein pathways. To date, the AT1R conformation induced by membrane stretch in the absence of ligand was thought to be the same as that induced by β-arrestin-biased agonists, which selectively engage β-arrestin thereby preventing G protein coupling...
December 12, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29230939/normative-values-and-factors-affecting-water-perfused-esophageal-high-resolution-impedance-manometry-for-a-chinese-population
#15
P-H Tseng, R K M Wong, J-F Wu, C-C Chen, C-H Tu, Y-C Lee, H-C Lee, H-P Wang, M-S Wu
BACKGROUND: Combined esophageal high-resolution impedance manometry (HRIM) measures multiple pressures and bolus transit simultaneously, facilitating detailed assessment of esophageal motility. Currently, normative values for water-perfused HRIM systems for Chinese populations are lacking. METHODS: Healthy volunteers were enrolled for comprehensive anthropometric measures, blood biochemistry tests, and an HRIM study using 22 water-perfused pressure sensors and 12 impedance channels...
December 12, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29230925/novel-pressure-sensors-and-bioreporters-in-the-synthetic-biology-era
#16
Miguel A Matilla
No abstract text is available yet for this article.
December 12, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29230603/amp-activated-protein-kinase-activation-in-mediating-phenylalanine-induced-neurotoxicity-in-experimental-models-of-phenylketonuria
#17
Lihua Lu, Xiaoming Ben, Lingling Xiao, Min Peng, Yongjun Zhang
Phenylketonuria (PKU), one of the most prevalent autosomal recessive disorders of amino acid metabolism, is characterized by abnormal accumulation of phenylalanine, which can lead to intellectual disability. The main pathologic changes in the central nervous system of untreated phenylketonuric patients are reductions in the number of axons, dendrites, and synapses in the brain. Such alterations are thought to be mainly associated with the toxic effects caused by phenylalanine. However, the underlying molecular mechanisms have not been fully elucidated...
December 11, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/29230438/a-programmable-optical-stimulator-for-the-drosophila-eye
#18
Xinping Chen, Walter D Leon-Salas, Taylor Zigon, Donald F Ready, Vikki M Weake
A programmable optical stimulator for Drosophila eyes is presented. The target application of the stimulator is to induce retinal degeneration in fly photoreceptor cells by exposing them to light in a controlled manner. The goal of this work is to obtain a reproducible system for studying age-related changes in susceptibility to environmental ocular stress. The stimulator uses light emitting diodes and an embedded computer to control illuminance, color (blue or red) and duration in two independent chambers...
October 2017: HardwareX
https://www.readbyqxmd.com/read/29230434/compressive-3d-ultrasound-imaging-using-a-single-sensor
#19
Pieter Kruizinga, Pim van der Meulen, Andrejs Fedjajevs, Frits Mastik, Geert Springeling, Nico de Jong, Johannes G Bosch, Geert Leus
Three-dimensional ultrasound is a powerful imaging technique, but it requires thousands of sensors and complex hardware. Very recently, the discovery of compressive sensing has shown that the signal structure can be exploited to reduce the burden posed by traditional sensing requirements. In this spirit, we have designed a simple ultrasound imaging device that can perform three-dimensional imaging using just a single ultrasound sensor. Our device makes a compressed measurement of the spatial ultrasound field using a plastic aperture mask placed in front of the ultrasound sensor...
December 2017: Science Advances
https://www.readbyqxmd.com/read/29230230/comparative-performance-of-ground-vs-aerially-assessed-rgb-and-multispectral-indices-for-early-growth-evaluation-of-maize-performance-under-phosphorus-fertilization
#20
Adrian Gracia-Romero, Shawn C Kefauver, Omar Vergara-Díaz, Mainassara A Zaman-Allah, Boddupalli M Prasanna, Jill E Cairns, José L Araus
Low soil fertility is one of the factors most limiting agricultural production, with phosphorus deficiency being among the main factors, particularly in developing countries. To deal with such environmental constraints, remote sensing measurements can be used to rapidly assess crop performance and to phenotype a large number of plots in a rapid and cost-effective way. We evaluated the performance of a set of remote sensing indices derived from Red-Green-Blue (RGB) images and multispectral (visible and infrared) data as phenotypic traits and crop monitoring tools for early assessment of maize performance under phosphorus fertilization...
2017: Frontiers in Plant Science
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