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https://www.readbyqxmd.com/read/28944153/sequential-development-of-non-arteritic-anterior-ischemic-optic-neuropathy-in-a-patient-on-hemodialysis
#1
Mukesh Jain, Renuka Srinivasan, K Ramesh Babu, M Swapnil Parchand
Purpose: Non-arteritic anterior ischemic optic neuropathy (NA-AION) is typically a disorder of patients 50 years and older predisposed to the vascular and structural optic disc risk factors. We present an interesting case of sequential development of NA-AION in a 45-year-old patient with end-stage renal disease undergoing hemodialysis. Methods: Observational case report. Results: A 45-year-old female on hemodialysis for chronic renal failure complained of sequential acute onset sudden painless gross diminution of vision in right eye followed by the left eye...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28943826/the-use-of-daptomycin-to-treat-methicillin-resistant-staphylococcus-epidermidis-bacteremia-in-a-critically-ill-child-with-renal-failure
#2
Stephen Morris, Kate Gould, Lee P Ferguson
Daptomycin is excreted primarily unchanged by the kidney. Dosage regimens in children with renal failure remain to be determined. We report the case of an 8-year-old child with multiorgan failure undergoing continuous peritoneal dialysis, successfully treated with intravenous daptomycin for methicillin-resistant Staphylococcus epidermidis bacteremia. A dosage of 8 mg/kg every 48 hour was used. Plasma peak and trough concentrations of daptomycin were 68 mg/L and 14.6 mg/L, respectively, on day 6 of treatment...
July 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/28943457/clinical-staging-of-fibrodysplasia-ossificans-progressiva-fop
#3
Robert J Pignolo, Frederick S Kaplan
Fibrodyplasia ossificans progressiva (FOP) is an ultra-rare genetic condition of heterotopic ossification (HO) that results in progressive loss of joint function, ultimately rendering movement impossible. Death is most commonly the result of thoracic insufficiency syndrome, or complications related to recurrent respiratory infections. There are no current treatments for FOP, but early and emerging clinical trials offer hope for this devastating disease. With the recent reporting of a comprehensive global natural history study, scales to assess joint dysfunction, and a more accurate prediction of joint survival, it is now possible to construct a conceptual framework for the clinical staging of FOP...
September 21, 2017: Bone
https://www.readbyqxmd.com/read/28942782/eighth-annual-intermacs-report-special-focus-on-framing-the-impact-of-adverse-events
#4
James K Kirklin, Francis D Pagani, Robert L Kormos, Lynne W Stevenson, Elizabeth D Blume, Susan L Myers, Marissa A Miller, J Timothy Baldwin, James B Young, David C Naftel
BACKGROUND: The Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) database now includes >20,000 patients from >180 hospitals. METHODS: The eighth annual report of INTERMACS updates the first decade of patient enrollment. RESULTS: In the current era, >95% of implants are continuous flow devices. Overall survival continues to remain >80% at 1 year and 70% at 2 years. Review of major adverse events shows minimal advantage for patients with ambulatory heart failure pre-implant...
October 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28942776/clinician-perspectives-on-the-management-of-abnormal-subcritical-tests-in-an-urban-academic-safety-net-health-care-system
#5
Cassidy Clarity, Urmimala Sarkar, Jonathan Lee, Margaret A Handley, L Elizabeth Goldman
BACKGROUND: Missed or delayed follow-up of abnormal subcritical tests (tests that do not require immediate medical attention) can lead to poor patient outcomes. Safety-net health systems with limited resources and socially complex patients are vulnerable to safety gaps resulting from delayed management. Clinician perspectives to identify system challenges, vulnerable situations, and potential solutions were sought in focus groups. METHODS: Five semistructured focus groups were conducted in 2015 with purposefully sampled clinicians from radiology, hospital medicine, emergency medicine, risk management, and ambulatory care from an urban, academic, integrated, safety-net health system...
October 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28942775/missed-diagnosis-of-cardiovascular-disease-in-outpatient-general-medicine-insights-from-malpractice-claims-data
#6
Gene R Quinn, Darrell Ranum, Ellen Song, Margarita Linets, Carol Keohane, Heather Riah, Penny Greenberg
BACKGROUND: Diagnostic errors are an underrecognized source of patient harm, and cardiovascular disease can be challenging to diagnose in the ambulatory setting. Although malpractice data can inform diagnostic error reduction efforts, no studies have examined outpatient cardiovascular malpractice cases in depth. A study was conducted to examine the characteristics of outpatient cardiovascular malpractice cases brought against general medicine practitioners. METHODS: Some 3,407 closed malpractice claims were analyzed in outpatient general medicine from CRICO Strategies' Comparative Benchmarking System database-the largest detailed database of paid and unpaid malpractice in the world-and multivariate models were created to determine the factors that predicted case outcomes...
October 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28942774/evaluation-of-patient-and-family-outpatient-complaints-as-a-strategy-to-prioritize-efforts-to-improve-cancer-care-delivery
#7
Jennifer W Mack, Joseph Jacobson, David Frank, Angel M Cronin, Kathleen Horvath, Victoria Allen, Jennifer Wind, Deborah Schrag
BACKGROUND: Limited systematic data about complaints related to cancer care are available. Patient complaints related to ambulatory care at a large academic cancer center were examined to better understand patient experiences of care and prioritize opportunities for quality improvement. METHODS: Content analysis of outpatient complaints made to the Patient/Family Relations Office at Dana-Farber Cancer Institute, Boston, in a two-year period (January 2013-December 2014) were conducted...
October 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28942618/office-blood-pressure-is-lower-than-awake-ambulatory-blood-pressure-at-lower-targets-for-treatment
#8
Martin G Myers, Janusz Kaczorowski
No abstract text is available yet for this article.
September 24, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28942606/daytime-napping-and-ambulatory-blood-pressure-monitoring-relevancy-in-asian-populations
#9
Michael Bursztyn
No abstract text is available yet for this article.
September 24, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28942600/investing-in-our-future-the-importance-of-ambulatory-visits-to-achieving-blood-pressure-control-in-young-adults
#10
Holly C Gooding, Courtney A Brown, Lauren E Wisk
No abstract text is available yet for this article.
September 24, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28941285/femoral-neck-shaft-angle-and-climate-induced-body-proportions
#11
Stephanie L Child, Libby W Cowgill
OBJECTIVES: Declination in femoral neck-shaft angle (NSA) is commonly linked to an increased level of physical activity during life. More recently, however, research suggests that lower NSA might also be explained, in part, as the mechanical consequence of differences in ecogeographic body proportions. This study tests the proposed link between NSA and climatic-induced body proportions, using relative body mass (RBM), throughout the course of development. MATERIALS AND METHODS: NSA and RBM were collected for 445 immature remains from five geographic locations...
September 23, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28940881/diagnostic-yield-of-asymptomatic-arrhythmias-detected-by-mobile-cardiac-outpatient-telemetry-and-autotrigger-looping-event-cardiac-monitors
#12
Wayne M Derkac, Jeffrey R Finkelmeier, Daniel J Horgan, Mathew D Hutchinson
INTRODUCTION: Asymptomatic arrhythmias can have important therapeutic implications in certain patient populations, for example, atrial fibrillation in patients with prior ischemic stroke. We sought to compare the diagnostic yield of two commercially available monitoring systems with automated arrhythmia detection algorithms. METHODS: We queried a large, proprietary database containing rhythm data for patients receiving ambulatory EKG monitoring (BioTelemetry, Malvern, PA)...
September 22, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28940596/the-prescription-of-antiplatelet-medication-in-a-very-elderly-population-an-observational-study-in-15%C3%A2-141-ambulatory-subjects
#13
Patrick Manckoundia, Jean-Baptiste Buzens, Rachid Mahmoudi, Philippe d'Athis, Isabelle Martin, Caroline Laborde, Didier Menu, Alain Putot
OBJECTIVE: Despite the frequent use of antiplatelet medication (AM) in the elderly patients, very few studies have investigated its prescription. We describe AM prescription through retrospective study in ambulatory elderly patients. METHOD: All subjects aged over 80 years with a medical prescription delivered in March 2015 and affiliated to the Mutualité Sociale Agricole de Bourgogne. Subjects with prescriptions for AM were compared with those without. RESULTS: A total of 15 141 ambulatory elderly patients (83-89 years, 61...
September 21, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28940546/measuring-emergency-department-patient-population-acuity
#14
Maame Yaa A B Yiadom, Christopher W Baugh, Tyler W Barrett, Xulei Liu, Alan B Storrow, Timothy J Vogus, Vikram Tiwari, Corey M Slovis, Stephan Russ, Dandan Liu
BACKGROUND: Emergency department (ED) acuity is the general level of patient illness, urgency for clinical intervention, and intensity of resource use in an ED environment. The relative strength of commonly used measures of ED acuity is not well understood. METHODS: We performed a retrospective cross-sectional analysis of ED-level data to evaluate the relative strength of association between commonly used proxy measures with a full spectrum measure of ED acuity...
September 23, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28940503/measuring-arterial-blood-pressure-in-humans-auscultatory-and-automatic-measurement-techniques-for-human-biological-field-studies
#15
Gary D James, Linda M Gerber
Human biologists have been examining arterial blood pressure since they began studying the effects of the environment and culture on the health of diverse populations. The Korotkoff auscultatory technique with a trained observer and aneroid sphygmomanometer is the method of choice for blood pressure measurement in many bioanthropological field contexts. Korotkoff sounds (the first and fifth phases) are the preferred determinants of systolic and diastolic pressure, even in infants, children, pregnant women, and the elderly...
September 22, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28939249/sudden-cardiac-death-in-a-dog-during-holter-recording-r-on-t-phenomenon
#16
T Gunasekaran, R A Sanders
A 6-year-old castrated male Golden Retriever was diagnosed with severe subaortic stenosis with severe left atrial enlargement and high heart rate due to atrial fibrillation. Treatment with digoxin and diltiazem to control ventricular response rate was initiated. Ambulatory electrocardiographic monitoring (Holter monitoring) was performed at the beginning of treatment and was repeated to evaluate the patient's response to drug therapy. Drug dose adjustments were made based on response to therapy as assessed by Holter monitoring...
September 19, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28938983/development-of-a-fall-prevention-program-in%C3%A2-the-ambulatory-surgery-setting
#17
Melissa LeCuyer, Barbara Lockwood, Maryanne Locklin
Falls are a major concern in the quality and safety of patient care in health care today. Falls contribute to serious injury, increased lengths of stay, and increased costs in the health care industry. This article provides a comprehensive literature review on falls and includes recommendations for the development of a comprehensive fall prevention program focusing on strategies and interventions required for the prevention of falls in an ambulatory surgery setting.
October 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28938966/high-screen-failure-rate-in-patients-with-resistant-hypertension-findings-from-symplicity-htn-3
#18
Ron Waksman, George L Bakris, Arie Steinvil, Hector Garcia-Garcia, Angela L Brown, William DiFilippo, Thomas Scott, Jasvindar Singh, Vanessa DeBruin, Denise Jones, Dan Jolivette, Deepak L Bhatt
BACKGROUND: The SYMPLICITY HTN-3 trial, which randomized subjects to renal denervation (RDN) or sham control, was designed to evaluate the efficacy and safety of RDN for the treatment of resistant hypertension. Outcomes were previously reported. This retrospective analysis evaluated reasons for screen failure (SF) for randomization in the trial. METHODS: SYMPLICITY HTN-3 enrolled subjects with office systolic blood pressure (SBP) ≥160 mmHg on stable and maximal doses of ≥3 antihypertensive medication classes...
October 2017: American Heart Journal
https://www.readbyqxmd.com/read/28938085/understanding-humerus-fractures-in-young-children-abuse-or-not-abuse
#19
Norell Rosado, Elizabeth Ryzna, Emalee G Flaherty
Fractures are the second most common abusive injury occurring in young children, particularly those under 2 years of age. The humerus is often affected. To better identify factors discriminating between abusive and non-abusive humerus fractures, this retrospective study examined the characteristics and mechanisms of injuries causing humerus fractures in children less than 18 months of age. Electronic medical records were reviewed for eligible patients evaluated between September 1, 2007 and January 1, 2012 at two children's hospitals in Chicago, IL...
September 18, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28937551/frequency-of-severe-infusion-reactions-associated-with-outpatient-infusion-of-infliximab-without-premedications
#20
Stephanie Q Hutsell, May Wu, K T Park
In this report, we describe incremental changes, during a 2-year period at a single center with the administration of maintenance infliximab infusions. Given practice-driven changes consisting of 1-hour infusions and omission of premedications, we aimed to investigate if these changes contributed to severe infusion reactions. We reviewed approximately 900 infliximab infusions in a pediatric ambulatory infusion center from January 1, 2014, to December 31, 2015, for severe adverse reactions requiring either rescue epinephrine or a code blue or "rapid response" activation...
October 2017: Journal of Pediatric Gastroenterology and Nutrition
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