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https://www.readbyqxmd.com/read/29245106/cerebral-arterio-venous-malformations-in-the-paediatric-population-angiographic-characteristics-multimodal-treatment-strategies-and-outcome
#1
Klaus-Peter Stein, Bernd-Otto Huetter, Sophia Goericke, Neriman Oezkan, Rebecca Leyrer, I Erol Sandalcioglu, Michael Forsting, Ulrich Sure, Oliver Mueller
OBJECTIVES: Cerebral arterio-venous malformations (AVM) are considered congenital lesions, emerging as an important cause of haemorrhagic stroke in children. The potential influence of age on clinical presentation and angio-architecture have been analysed extensively in the last years. Yet, comparative studies comprising ascending age groups may be limited in their conclusions, especially when comparing young children and adults. It is the aim of this study to evaluate characteristic clinical and angiographic features of AVM within a paediatric subgroup and their correlation to age at presentation...
December 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29244983/allogeneic-stem-cell-transplant-for-acute-myeloid-leukemia-evolution-of-an-effective-strategy-in-india
#2
Abhijeet Ganapule, Sandeep Nemani, Anu Korula, Kavitha M Lakshmi, Aby Abraham, Alok Srivastava, Poonkuzhali Balasubramanian, Biju George, Vikram Mathews
Purpose There are limited data from developing countries on the role and cost-effectiveness of allogeneic stem cell transplantation (allo-SCT) for patients with acute myeloid leukemia (AML). Patients and Methods We undertook a retrospective descriptive study of all patients with AML who underwent allo-SCT from 1994 to 2013 at our center to evaluate the clinical outcomes and cost-effectiveness of this therapeutic modality. Results Two hundred fifty-four consecutive patients, median age 34 years, who underwent allo-SCT at our center were included in this study...
December 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29244847/cognitive-failures-in-late-adulthood-the-role-of-age-social-context-and-depressive-symptoms
#3
Paul Kenneth Hitchcott, Maria Chiara Fastame, Dalila Langiu, Maria Pietronilla Penna
The incidence of self-reported cognitive failures among older adults may be an index of successful cognitive aging. However, self-reported cognitive failures are biased by variation in depressive symptomatology. This study examined age-related and socio-cultural context effects on cognitive failures while controlling for depressive symptoms. Both overall and specific factors of cognitive failures were determined. A further goal was to investigate the relationship between working memory and cognitive efficiency measures and cognitive failures...
2017: PloS One
https://www.readbyqxmd.com/read/29244841/individual-preferences-for-physical-exercise-as-secondary-prevention-for-non-specific-low-back-pain-a-discrete-choice-experiment
#4
Emmanuel Aboagye, Jan Hagberg, Iben Axén, Lydia Kwak, Malin Lohela-Karlsson, Eva Skillgate, Gunilla Dahlgren, Irene Jensen
BACKGROUND: Exercise is effective in improving non-specific low back pain (LBP). Certain components of physical exercise, such as the type, intensity and frequency of exercise, are likely to influence participation among working adults with non-specific LBP, but the value and relative importance of these components remain unknown. The study's aim was to examine such specific components and their influence on individual preferences for exercise for secondary prevention of non-specific LBP among working adults...
2017: PloS One
https://www.readbyqxmd.com/read/29244763/bisphenol-a-causes-liver-damage-and-selectively-alters-the-neurochemical-coding-of-intrahepatic-parasympathetic-nerves-in-juvenile-porcine-models-under-physiological-conditions
#5
Michael Thoene, Liliana Rytel, Ewa Dzika, Andrzej Włodarczyk, Ewa Kruminis-Kaszkiel, Ptaszyński Konrad, Joanna Wojtkiewicz
Bisphenol A (BPA) is an extremely common polymer that is used in typical everyday products throughout the world, especially in food and beverage containers. Within the last ten years, it has been found that the BPA monomer tends to leach into foodstuffs, and nanogram concentrations of it may cause a variety of deleterious health effects. These health problems are very evident in developing children and in young adults. The aim of this study was to expose developing pigs to dietary BPA at both legally acceptable and ten-fold higher levels...
December 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29244624/the-effects-of-psychosocial-deprivation-on-attachment-lessons-from-the-bucharest-early-intervention-project
#6
Nathan A Fox, Charles A Nelson, Charles H Zeanah
The absence of typical caregiving, including warm and responsive parenting, has been suggested to significantly affect the young child's ability to form adaptive relationships with adults and peers. The Bucharest Early Intervention Project (BEIP), a randomized controlled trial of foster/family care for young children with a history of institutionalization has provided the context to assess these relationships. Here we review data from the BEIP with specific focus on attachment. The findings clearly show the importance of early family care on the emergence of attachment, on the prevention of psychopathology, and on links between brain and social behavior...
2017: Psychodynamic Psychiatry
https://www.readbyqxmd.com/read/29244527/motivations-for-extradyadic-infidelity-revisited
#7
Dylan Selterman, Justin R Garcia, Irene Tsapelas
Relationship infidelities are motivated by many distinct factors, with previous research indicating motivations of dissatisfaction, neglect, anger, and sexual desire (Barta & Kiene, 2005). We expand on this by demonstrating additional, empirically distinct motivations for infidelity. Using an Internet-based questionnaire, participants (N = 495), most of whom were young adults, self-reported their infidelities. In addition to evidence for previously studied motivations, our data demonstrate additional factors, including lack of love ("I had 'fallen out of love with' my primary partner"), low commitment ("I was not very committed to my primary partner"), esteem ("I wanted to enhance my popularity"), gaining sexual variety ("I wanted a greater variety of sexual partners"), and situational factors ("I was drunk and not thinking clearly")...
December 15, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29244245/substance-p-in-dorsal-root-ganglion-neurons-in-young-and-adult-rats-after-nociceptive-stimulation-during-the-neonatal-period
#8
Ana Leda Bertoncini Simões, Greice Anne Rodrigues Silva, Carolina Giorgetto, Elisabete de Cassia do Carmo-Campos, Fernando José Dias, Valéria Paula Sassoli Fazan
The nervous system is highly plastic during the neonatal period, being sensitive to noxious stimuli, which may cause short- and long-term pain responsivity changes. Understanding plasticity in peripheral pain pathways is crucial, particularly when the nervous system is still under development and remodeling process. Substance P (SP) is widely used as a marker for peripheral neurons with unmyelinated and small myelinated fibers. We investigated the number of SP immunoreactive neurons in the dorsal root ganglion (DRG) of male and female Wistar rats, 15 and 180 days after nociceptive stimulation during the neonatal period...
December 15, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29244203/pediatric-tolerogenic-dcs-expressing-cd4-and-immunoglobulin-like-transcript-receptor-ilt-4-secrete-il-10-in-response-to-fc-and-adenosine
#9
Alessandra Franco, Jeetendra Kumar, Gene Lin, Negar Behnamfar, Li-En Hisieh, Chisato Shimizu, Adriana H Tremoulet, Jane C Burns, Joel Linden
We characterized a novel population of tolerogenic myeloid dendritic cells (tmDCs) defined as CD11c+ CD11b+ CD14+ CD4+ and immunoglobulin-like transcript receptor (ILT)-4+ that are significantly more abundant in the circulation of infants and young children than in adults. TmDCs secrete the immunosuppressive lymphokine interleukin (IL)-10 when stimulated with the heavy constant region of immunoglobulins (Fc) and express high levels of the adenosine A2A receptor (A2A R), which, when activated by adenosine, inhibits the release of pro-inflammatory cytokines from most immune cells...
December 15, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/29244117/quality-of-life-self-esteem-and-future-expectations-of-adolescent-and-young-adult-cancer-survivors
#10
Kareen N Tonsing, Rosaleen Ow
Significant advancements in treatment modalities over the past few decades have significantly improved the survival rates of many types of childhood cancer, directing attention to the psychosocial consequences of successful treatment and subsequent survival. This study assesses quality of life (QoL) among survivors of childhood cancer. Data were collected by means of a survey questionnaire. Participants were assured of confidentiality and of the voluntary nature of participation. Participants ranged in age from 12 to 24 years (mean age = 17...
December 13, 2017: Health & Social Work
https://www.readbyqxmd.com/read/29244112/the-effect-of-descriptive-age-norms-on-the-motivation-to-exercise-among-older-adults
#11
Johan Pelssers, Katrien Fransen, Norbert Vanbeselaere, Filip Boen
Based on the principles of the Social Identity Approach (SIA), the present experiment aimed to examine the impact of communicating descriptive age norms on older adults' autonomous motivation to exercise. Under the cover of a marketing study, older adults (n = 120; age = 65-70 years) participated in a newly created exercise activity, 'Pattern Stepping'. This activity was framed as an activity that was descriptively normative either for older adults, for younger adults, for both groups, or for none. Repeated measures ANOVAs revealed that participants felt greater satisfaction of their basic psychological needs and were more autonomously motivated to exercise if Pattern Stepping was framed as an activity popular among the young, rather than among older adults...
December 12, 2017: Health Promotion International
https://www.readbyqxmd.com/read/29244061/association-between-sustained-poverty-and-changes-in-body-mass-index-from-1990-to-2015-the-coronary-artery-risk-development-in-young-adults-study
#12
Tali Elfassy, M Maria Glymour, Kiarri N Kershaw, Mercedes Carnethon, Maria M Llabre, Cora E Lewis, Neil Schneiderman, Adina Zeki Al Hazzouri
We sought to determine whether sustained poverty is associated with change in body mass index (BMI) among 4,762 black and white adults of the Coronary Artery Risk Development In Young Adults study. Household income in the past year and current BMI were measured at seven visits between 1990 and 2015. Sustained poverty was the proportion of visits during which household income was below 200% of the federal poverty level (range, 0%-100%). Sustained poverty and BMI were time-updated. Mean age in 1990 was 30 years...
December 13, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29244046/humor-a-rehabilitative-tool-in-the-post-intensive-care-of-young-adults-with-acquired-brain-injury
#13
Kate O'Reilly
PURPOSE: The aim of the study was to describe how paid carers use humor in providing compassionate post-intensive rehabilitation care to young adults with acquired brain injury (ABI) who are unable to perform or direct their own care. DESIGN: This is a qualitative study underpinned by symbolic interactionism. METHODS: Paid carers in a residential aged care facility were interviewed. Interview data were analyzed using grounded theory methods of coding, comparative analysis, memoing, and theoretical sampling...
July 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29243875/allometric-considerations-when-assessing-aortic-aneurysms-in-turner-syndrome-implications-for-activity-recommendations-and-medical-decision-making
#14
Holly Corbitt, Cheryl Maslen, Siddharth Prakash, Shaine A Morris, Michael Silberbach
In Turner syndrome, the potential to form thoracic aortic aneurysms requires routine patient monitoring. However, the short stature that typically occurs complicates the assessment of severity and risk because the relationship of body size to aortic dimensions is different in Turner syndrome compared to the general population. Three allometric formula have been proposed to adjust aortic dimensions, all employing body surface area: aortic size index, Turner syndrome-specific Z-scores, and Z-scores based on a general pediatric and young adult population...
December 15, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29243388/the-treatment-outcomes-of-antiretroviral-substitutions-in-routine-clinical-settings-in-asia-data-from-the-treat-asia-hiv-observational-database-tahod
#15
In Young Jung, David Boettiger, Wing Wai Wong, Man Po Lee, Sasisopin Kiertiburanakul, Romanee Chaiwarith, Anchalee Avihingsanon, Junko Tanuma, Nagalingeswaran Kumarasamy, Adeeba Kamarulzaman, Fujie Zhang, Pacharee Kantipong, Oon Tek Ng, Benedict Lim Heng Sim, Matthew Law, Jeremy Ross, Jun Yong Choi
INTRODUCTION: Although substitutions of antiretroviral regimen are generally safe, most data on substitutions are based on results from clinical trials. The objective of this study was to evaluate the treatment outcomes of substituting antiretroviral regimen in virologically suppressed HIV-infected patients in non-clinical trial settings in Asian countries. METHODS: The study population consisted of HIV-infected patients enrolled in the TREAT Asia HIV Observational Database (TAHOD)...
December 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29243257/differential-impact-of-tongue-exercise-on-intrinsic-lingual-muscles
#16
Miranda J Cullins, Brittany N Krekeler, Nadine P Connor
OBJECTIVES/HYPOTHESIS: Aging is associated with muscle fiber hypotrophy and decreased percentages of rapidly contracting myosin heavy chain (MyHC) type IIb muscle fibers. Tongue exercise programs used to treat dysphagia target age-related decline in tongue muscle function, but the impact of exercise on the intrinsic tongue muscles is unknown. We hypothesized that exercise would induce muscle fiber hypertrophy and increase the percentage of MyHC IIa fibers in the intrinsic tongue. STUDY DESIGN: Animal model...
December 15, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29243211/manganese-concentrations-in-tissues-and-skin-of-three-dolphin-species-stranded-in-the-croatian-waters-of-the-adriatic-sea-from-1995-to-2013
#17
Maja Đokić, Nina Bilandžić, Marija Sedak, Martina Đuras, Tomislav Gomerčić, Miroslav Benić, Tomislav Bolanča
Manganese concentrations were determined in muscle, kidney, liver, spleen, lung and fat tissues and skin of three cetacean species, the bottlenose (Tursiops truncatus), striped (Stenella coeruleoalba) and Risso's (Grampus griseus) dolphins, stranded along the Croatian Adriatic coast between 1995 and 2013. Mean ranges determined in tissues were (mg/kg, ww): muscle 0.23-0.27, liver 2.87-4.00, kidney 0.66-1.26, spleen 0.37-0.79, lung 0.18-0.57, skin 0.11-0.97, fat 0.06-0.42. The highest Mn mean levels in tissues were measured in species (mg/kg, ww): T...
December 14, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29243156/comfort-eating-and-all-cause-mortality-in-the-us-health-and-retirement-study
#18
Jenna R Cummings, Ashley E Mason, Eli Puterman, A Janet Tomiyama
PURPOSE: Comfort eating is a prevalent behavior. Prior research shows that comfort eating is associated with reduced stress responses and increased metabolic risk across adolescence, young adulthood, and middle adulthood. The purpose of the current research was to test if comfort eating prospectively predicted all-cause mortality in older adulthood. METHOD: The US Health and Retirement Study is an ongoing, nationally representative, longitudinal study of older adults...
December 14, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29242954/-abdominal-lymphatic-malformations-german-version
#19
REVIEW
W A Wohlgemuth, L M Dendl, R Brill, F Stangl, D Stoevesandt, A G Schreyer
BACKGROUND: Abdominal lymphatic malformations (LM) are relatively rare findings in the differential diagnosis of focal abdominal lesions; however, they represent a challenge especially in younger patients. The aim of this review article is to provide up-to-date information about the different kinds of LM manifestations. In addition, related syndromes and typical imaging features to facilitate the diagnosis are discussed. RESULTS: The clinical presentation of abdominal LM is unspecific, whereby most are asymptomatic and comprise incidental findings of thin-walled cystic masses anywhere in the abdomen...
December 14, 2017: Der Radiologe
https://www.readbyqxmd.com/read/29242802/resistant-non-union-of-humerus-after-intramedullary-nailing-treated-with-locking-compression-plate-with-bone-grafting-with-nail-in-situ-and-shoulder-spica-a-case-report
#20
Jagdeep Singh, Anoop Kalia, Kavin Khatri, Anshul Dahuja
Introduction: Humerus non-union is a challenging situation for the surgeon and devastating and morbid situation for the patient. Surgical approach to the humerus is demanding because of the complex neurovascular anatomy and especially when previous surgeries have been attempted. Case Report: We report a case of a young adult male who sustained a compound fracture of humerus shaft treated with intramedullary nailing followed by subsequent bone grafting and eventually landed up in non-union and was treated at our center by locking compression plate application with nail in situ with iliac crest autogenous bone graft followed by shoulder spica application...
September 2017: Journal of Orthopaedic Case Reports
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