Kumar Vaibhav, Mayuri Gulhane, Pankaj Ahluwalia, Manish Kumar, Meenakshi Ahluwalia, Ashiq M Rafiq, Vibha Amble, Manuela G Zabala, Jacob B Miller, Liam Goldman, Ashis K Mondal, Ferenc Deak, Ravindra Kolhe, Ali S Arbab, Fernando L Vale
Traumatic brain injury (TBI) is one of the foremost causes of disability and mortality globally. While the scientific and medical emphasis is to save lives and avoid disability during acute period of injury, a severe health problem can manifest years after injury. For instance, TBI increases the risk of cognitive impairment in the elderly. Remote TBI history was reported to be a cause of the accelerated clinical trajectory of Alzheimer's disease-related dementia (ADRD) resulting in earlier onset of cognitive impairment and increased AD-associated pathological markers like greater amyloid deposition and cortical thinning...
May 11, 2024: GeroScience