Yuri Ono, Kazuo Terashima, Aimin Liu, Munehiro Yokoyama, Kazuhiro Yokoshima, Miki Mizukami, Ken Watanabe, Yoko Mochimaru, Tohru Furusaka, Norio Shimizu, Naoki Yamamoto, Toshiyuki Ishiwata, Yuuichi Sugisaki, Toshiaki Yagi, Zenya Naito
Neoplasm of follicular dendritic cells (FDC), follicular dendritic cell sarcoma (FDCS), is a rare tumor of intermediate to high-grade malignancy in lymph nodes and visceral organs. Reported herein is a case of FDCS arising from cervical lymph nodes in a 16-year-old Japanese boy, who died of the disease 3 years after diagnosis. The tumor cells were pale eosinophilic and elongated with euchromatic nuclei and were positive for CD21, clusterin, and CNA-42 on immunohistochemistry, as well as desmosome-like junctions on electron microscopy...
May 2009: Pathology International