keyword
MENU ▼
Read by QxMD icon Read
search

Point-of-Care

keyword
https://www.readbyqxmd.com/read/29656593/review-article-investigations-and-the-pregnant-woman-in-the-emergency-department-part-1-laboratory-investigations
#1
REVIEW
Adam Morton, Stephanie Teasdale
Accurate assessment of the pregnant patient in the ED depends on knowledge of physiological changes in pregnancy, and how these changes may impact on pathology tests, appearance on point-of-care ultrasound and electrocardiography. In addition the emergency physician needs to be cognisant of disorders that are unique to or more common in pregnancy. Part 1 of this review addresses potential deviations in laboratory investigation reference intervals resulting from physiological alterations in pregnancy, and the important causes of abnormal laboratory results in pregnancy...
April 15, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29656390/documenting-the-growth-of-ultrasound-research-in-emergency-medicine-through-a-bibliometric-analysis-of-accepted-academic-conference-abstracts
#2
Michael I Prats, David P Bahner, Ashish R Panchal, Andrew M King, David P Way, Stephen Lin, J Christian Fox, Creagh T Boulger
OBJECTIVES: Ultrasound (US) has become an indispensable skill for emergency physicians. Growth in the use of US in emergency medicine (EM) has been characterized by practice guidelines, education requirements, and the number of EM US practitioners. Our purpose was to further document the growth of EM US by profiling the breadth, depth, and quality of US-related research presented at EM's most prominent annual research conference: the Society for Academic Emergency Medicine Annual Meeting...
April 15, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29652744/clinical-pearls-part-3-anaesthetic-management-of-abnormally-invasive-placentation
#3
Vinod Patil, Gamunu Ratnayake, Galina Fastovets, D S Wijayatilake
PURPOSE OF REVIEW: Abnormal placentation is a clinical condition seen increasingly in the pregnant population. It is associated with significant morbidity and mortality, which may be mitigated through robust multidisciplinary care for these patients. The role of maternal critical care for these patients has largely been ignored in the literature. RECENT FINDINGS: Advances in pharmacological management of bleeding with recent publications of large multicentre trials in addition to new technologies in the management of massive obstetric haemorrhage (MOH) have revolutionized the management of abnormal placentation...
April 12, 2018: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29652490/immunoassay-multiplexing-on-a-cmos-photodiode-array
#4
Bence Nagy, Mohammed Al-Rawhani, Boon Chong Cheah, Michael P Barrett, David R S Cumming
Scalable immunoassay multiplexing offers a route to creating rapid point-of-care (POC) diagnostics. We present a method for multiplexing immunoassays on the surface of a complementary metal-oxide-semiconductor (CMOS) sensor array integrated circuit (IC) without the use of physical separators such as wells or channels. Major advantages of using a CMOS sensor array include low mass-manufacturing costs, the possibility to multiplex multiple assays on a single IC and improved signal when averaging multiple sensors, along with providing a platform where wash steps can be incor-porated to maximize selectivity and sensitivity compared to paper based lateral flow immunoassay...
April 13, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29652173/a-review-of-commercially-available-point-of-care-devices-to-concentrate-bone-marrow-for-the-treatment-of-osteoarthritis-and-focal-cartilage-lesions
#5
Florian Gaul, William D Bugbee, Heinz R Hoenecke, Darryl D D'Lima
Objective Mesenchymal stem cells (MSCs) are a promising cell-based therapy treatment option for several orthopedic indications. Because culture expansion of MSC is time and cost intensive, a bedside concentration of bone marrow (BM) aspirate is used as an alternative. Many commercial systems are available but the available literature and knowledge regarding these systems is limited. We compared different point-of-care devices that concentrate BM (BMC) by focusing on technical features and quality parameters to help surgeons make informed decisions while selecting the appropriate device...
April 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29651956/quantitative-vascular-evaluation-from-laboratory-experiments-to-point-of-care-patient-clinical-approach
#6
Ricardo L Armentano, Leandro J Cymberknop
To aid in patient-specific risk stratification and diagnosis, an assessment of arterial structural and functional changes associated to a vascular disease in both early and advanced stages have been proposed in order to limit the progression or revert vascular alterations. To this end, an interdisciplinary international partnership made up by research institutions from France, Argentina, Uruguay and Spain was established, with the objective of contributing to the evaluation and follow-up of factors involved in the physiopathology of cardiometabolic diseases and human aging...
April 13, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29651944/role-of-point-of-care-ultrasonography-for-management-of-sepsis-and-septic-shock
#7
Gentle Sunder Shrestha, Shrikanth Srinivasan
BACKGROUND: Sepsis and septic shock remain a major cause of morbidity and mortality globally. In recent years, outcome of patients with sepsis and septic shock has gradually improved, in part due to early recognition and timely appropriate management. Bedside physical examination can be of limited value to identify the source of infection and to decide appropriate management. Moreover, the clinical status of these patients can change rapidly, as a part of disease progression or in response to treatment or intervention...
April 12, 2018: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/29650066/the-role-of-technology-in-the-bedside-encounter
#8
REVIEW
Andre Kumar, Gigi Liu, Jeff Chi, John Kugler
Technology has the potential to both distract and reconnect providers with their patients. The widespread adoption of electronic medical records in recent years pulls physicians away from time at the bedside. However, when used in conjunction with patients, technology has the potential to bring patients and physicians together. The increasing use of point-of-care ultrasound by physicians is changing the bedside encounter by allowing for real-time diagnosis with the treating physician. It is a powerful example of the way technology can be a force for refocusing on the bedside encounter...
May 2018: Medical Clinics of North America
https://www.readbyqxmd.com/read/29649748/rapid-and-selective-sampling-of-igg-from-skin-in-less-than-1-min-using-a-high-surface-area-wearable-immunoassay-patch
#9
Jacob W Coffey, Simon R Corrie, Mark A F Kendall
Microprojection array (MPA) patches are an attractive approach to selectively capture circulating proteins from the skin with minimal invasiveness for diagnostics at the point-of-care or in the home. A key challenge to develop this technology is to extract sufficient quantities of specific proteins from within the skin to enable high diagnostic sensitivity within a convenient amount of time. To achieve this, we investigated the effect of MPA geometry (i.e. projection density, length and array size) on protein capture...
March 22, 2018: Biomaterials
https://www.readbyqxmd.com/read/29649602/point-of-care-and-point-of-can-leveraging-reference-laboratory-capacity-for-integrated-diagnosis-of-fever-syndromes-in-the-tropics
#10
REVIEW
Makeda Semret, Momar Ndao, Jan Jacobs, Cedric P Yansouni
BACKGROUND: There is an urgent need for integrated diagnosis of febrile syndromes, able to account for multiple pathogens and inform decisions for clinical care and public health. AIMS: To reflect on the evolving roles of laboratory-based testing for non-malarial febrile illnesses (NMFI) in low-resource settings (LRS), and to consider how advances in diagnostics, in connectivity and transport, and in quality-systems implementation may substantially enhance the capacity of reference laboratories to bridge the current gap between remote passive surveillance and clinically meaningful integrated fever diagnosis...
April 9, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29648780/effective-bioactivity-retention-of-low-concentration-antibodies-on-hfbi-modified-fluorescence-icts-for-sensitive-and-rapid-detection-of-psa
#11
Bo Zhang, Weichen Gao, Jiafang Piao, Yunjie Xiao, Bin Wang, Weipan Peng, Xiaoqun Gong, Zefang Wang, Haitao Yang, Jin Chang
Nowadays, increasing analytical sensitivity is still a big challenge in constructing membrane-based fluorescence immunochromatography test strip (FICTS). However, the bioactivity of antibody (Ab) immobilized on the test line (T line) of porous nitrocellulose membrane (PNM), which directly influences the analytical sensitivity, is less studied. In this work, a novel amphiphilic hydrophobin (HFBI) protein was introduced to modify the T line to effectively retain the Abs' bioactivity. The results indicated that HFBI could self-assemble on the PNM and immobilize the Abs in the "stand-up" orientation...
April 12, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29648566/sers-based-lateral-flow-assay-for-quantitative-detection-of-c-reactive-protein-as-an-early-bio-indicator-of-a-radiation-induced-inflammatory-response-in-nonhuman-primates
#12
Zhen Rong, Rui Xiao, Shuang Xing, Guolin Xiong, Zuyin Yu, Limei Wang, Xiaofei Jia, Keli Wang, Yuwen Cong, Shengqi Wang
In accidental irradiation situations, rapid in-field evaluation of acute radiation syndrome is critical for effective triage and timely medical treatment of irradiated individuals. A surface-enhanced Raman scattering (SERS)-based lateral flow assay was developed for the quantitative detection of C-reactive protein (CRP) as an early bio-indicator of a radiation-induced inflammatory response in nonhuman primates. Raman reporter-embedded gold-core silver-shell nanoparticles with built-in hot spots were synthesized and conjugated with a CRP detection antibody to serve as SERS tags in the lateral flow assay...
April 12, 2018: Analyst
https://www.readbyqxmd.com/read/29645058/recent-advances-in-nanoparticle-based-lateral-flow-immunoassay-as-a-point-of-care-diagnostic-tool-for-infectious-agents-and-diseases
#13
REVIEW
Ruptanu Banerjee, Amit Jaiswal
Lateral flow immunoassay (LFIA) technology is a paper-based, point-of-care strip biosensor designed to detect a specific analyte in a given sample. This type of assay is now of great interest to researchers for its cost-effectiveness, simplicity, portability and rapidness of detection of analytes, including but not limited to areas such as agriculture, food, biomedicine and pathogen detection. Various nanoparticles (such as metal nanoparticles, carbon-based nanoparticles, quantum dots, lanthanides and up-converting phosphor) functionalized by an antibody to detect an analyte protein or molecular marker present in the surface of an infectious pathogen are used for in LFIAs...
April 12, 2018: Analyst
https://www.readbyqxmd.com/read/29644437/a-paperfluidic-platform-to-detect-neisseria-gonorrhoeae-in-clinical-samples
#14
Audrey L Horst, Justin M Rosenbohm, Nikunja Kolluri, Justin Hardick, Charlotte A Gaydos, Mario Cabodi, Catherine M Klapperich, Jacqueline C Linnes
Globally, the microbe Neisseria gonorrhoeae (NG) causes 106 million newly documented sexually transmitted infections each year. Once appropriately diagnosed, NG infections can be readily treated with antibiotics, but high-risk patients often do not return to the clinic for treatment if results are not provided at the point of care. A rapid, sensitive molecular diagnostic would help increase NG treatment and reduce the prevalence of this sexually transmitted disease. Here, we report on the design and development of a rapid, highly sensitive, paperfluidic device for point-of-care diagnosis of NG...
April 11, 2018: Biomedical Microdevices
https://www.readbyqxmd.com/read/29644056/lung-ultrasonography-in-end-stage-renal-disease-moving-from-evidence-to-practice-a-narrative-review
#15
Daniel W Ross, Mohammed M Abbasi, Kenar D Jhaveri, Mala Sachdeva, Ilene Miller, Richard Barnett, Mangala Narasimhan, Paul Mayo, Massini Merzkani, Anna T Mathew
Traditionally, point of care ultrasonography in nephrology has been used for renal biopsies and dialysis line placement. However, there is an emerging literature supporting the value of point of care lung ultrasonography in the assessment of volume status for dialysis patients. We conducted a review and identified 12 studies that examined the utility of lung ultrasonography in assessing volume status in patients with end-stage renal disease. We conclude that lung ultrasonography can be used to determine volume status in chronic dialysis patients by identifying lung congestion using the B-line score...
April 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29642875/comparing-the-performance-of-circulating-cathodic-antigen-and-kato-katz-techniques-in-evaluating-schistosoma-mansoni-infection-in-areas-with-low-prevalence-in-selected-counties-of-kenya-a-cross-sectional-study
#16
Collins Okoyo, Elses Simiyu, Sammy M Njenga, Charles Mwandawiro
BACKGROUND: Kato-Katz technique has been the mainstay test in Schistosoma mansoni diagnosis in endemic areas. However, recent studies have documented its poor sensitivity in evaluating Schistosoma mansoni infection especially in areas with lower rates of transmission. It's the primary diagnostic tool in monitoring impact of the Kenya national school based deworming program on infection transmission, but there is need to consider a more sensitive technique as the prevalence reduces. Therefore, this study explored the relationship between results of the stool-based Kato-Katz technique with urine-based point-of-care circulating cathodic antigen (POC-CCA) test in view to inform decision-making by the program in changing from Kato-Katz to POC-CCA test...
April 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29642733/warfarin-patients-with-anemia-show-trend-of-out-of-range-international-normalized-ratio-frequency-with-point-of-care-testing-in-an-anticoagulation-clinic
#17
Christina E DeRemer, Bliss McMichael, Henry N Young
INTRODUCTION: Many factors influence international normalized ratio (INR); however, few studies have examined the impact of anemia in warfarin patients. The primary objective of this study was to explore the relationship between in-clinic anemia and the control of INR within an anticoagulation clinic. METHODS: A retrospective chart review was performed on a random sample of patients seen in an academic medical center pharmacy-managed anticoagulation clinic. Hemochron® Signature Elite machine was utilized to monitor point-of-care (POC) INR...
January 1, 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29642606/metabolism-driven-high-throughput-cancer-identification-with-glut5-specific-molecular-probes
#18
Srinivas Kannan, Vagarshak V Begoyan, Joseph R Fedie, Shuai Xia, Łukasz J Weseliński, Marina Tanasova, Smitha Rao
Point-of-care applications rely on biomedical sensors to enable rapid detection with high sensitivity and selectivity. Despite advances in sensor development, there are challenges in cancer diagnostics. Detection of biomarkers, cell receptors, circulating tumor cells, gene identification, and fluorescent tagging are time-consuming due to the sample preparation and response time involved. Here, we present a novel approach to target the enhanced metabolism in breast cancers for rapid detection using fluorescent imaging...
April 10, 2018: Biosensors
https://www.readbyqxmd.com/read/29629759/evolution-of-a-thermophilic-strand-displacing-polymerase-using-high-temperature-isothermal-compartmentalized-self-replication
#19
John N Milligan, Raghav Shroff, Daniel J Garry, Andrew D Ellington
Strand-displacing polymerases are a crucial component of isothermal amplification (IA) reactions where the lack of thermal cycling reduces equipment needs and improves time-to-answer, especially for point of care applications. In order to improve the function of strand displacing polymerases, we have developed an emulsion-based directed evolution scheme, high temperature isothermal compartmentalized self-replication (HTI-CSR) that does not rely on thermal cycling. Starting from an algorithm-optimized shuffled library of exonuclease-deficient Family A polymerases from Geobacillus stearothermophilus (Bst LF) and Thermus aquaticus (Klentaq), we have applied HTI-CSR to generate a more thermostable strand displacing polymerase variant that performs well in Loop-mediated Isothermal Amplification (LAMP) and Rolling Circle Amplification (RCA), even after thermal challenges of up to 95°C that lead to better primer annealing...
April 9, 2018: Biochemistry
https://www.readbyqxmd.com/read/29629672/considerations-regarding-point-of-care-testing
#20
V Gounden
No abstract text is available yet for this article.
March 28, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
keyword
keyword
19957
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"