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spasticity in cp

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https://www.readbyqxmd.com/read/28437759/correlation-of-technical-surgical-goals-to-the-gdi-and-investigation-of-post-operative-gdi-change-in-children-with-cerebral-palsy
#1
Christina Bickley, Judi Linton, Nancy Scarborough, Elroy Sullivan, Katy Mitchell, Douglas Barnes
AIM: The purpose of this study was to introduce a standardized set of surgical technical achievement goals (TAGs) as part of a comprehensive outcome assessment model for children with spastic cerebral palsy (CP) undergoing orthopaedic surgical intervention to improve gait. Examination of relationships of these surgical goals to the Gait Deviation Index (GDI) and use of two assessments in tandem provided a thorough picture of technical surgical outcomes. This study also investigated changes in GDI in children with spastic CP after surgery...
April 13, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28428665/brain-lesions-in-children-with-unilateral-spastic-cerebral-palsy
#2
Feriha Hadzagic-Catibusic, Edin Avdagic, Smail Zubcevic, Sajra Uzicanin
INTRODUCTION: Unilateral spastic cerebral palsy (US CP) is the second most common subtype of cerebral palsy. AIM: The aim of the study was to analyze neuroimaging findings in children with unilateral spastic cerebral palsy. MATERIAL AND METHODS: The study was hospital based, which has included 106 patients with US CP (boys 72/girls 34, term 82/preterm 24). Neuroimaging findings were classified into 5 groups: Brain maldevelopment, predominant white matter injury, predominant gray matter injury, non specific findings and normal neuroimaging findings...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28427924/long-term-deterioration-of-perceived-health-and-functioning-in-adults-with-cerebral-palsy
#3
Joyce L Benner, Sander R Hilberink, Thessa Veenis, Henk J Stam, Wilma M A van der Slot, Marij E Roebroeck
OBJECTIVE: To describe longitudinal change in perceived health, presence of health issues and functional level in adults with cerebral palsy (CP). DESIGN: Prospective cohort study. SETTING: Participants who completed baseline assessments in 1996 or 2000 were invited for a long-term follow-up in 2010. PARTICIPANTS: Forty-nine Dutch adults with CP (age 35-45 years, 55% male, 75% spastic) formerly known in pediatric rehabilitation care...
April 17, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28421784/assessment-of-anthropometric-indicators-in-children-with-cerebral-palsy-according-to-the-type-of-motor-dysfunction-and-reference-standard
#4
Jorge Abraham García Iñiguez, Edgar Manuel Vásquez-Garibay, Andrea García Contreras, Enrique Romero-Velarde, Rogelio Troyo Sanromán
AIM: The study aimed to demonstrate that the assessment of the anthropomorphic measurements of children with cerebral palsy (CP) varies according to the type of motor dysfunction and references standard used for comparison. METHOD: In a cross-sectional design, 108 children 2 to 16 years were classified according to the type of motor dysfunction by gender and age group. Weight, mid-upper-arm-circumference (MUAC), and alternative measures for height were performed...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28418729/relationship-of-cognitive-functions-and-gross-motor-abilities-in-children-with-spastic-diplegic-cerebral-palsy
#5
Alaa Al-Nemr, Faten Abdelazeim
Spastic diplegic cerebral palsy can be accompanied by a myriad of symptoms affecting other body systems including cognitive dysfunction. The purpose of this study was to determine whether a relationship exists between cognitive functions in the form of selective attention and figural memory domains with standing and walking motor abilities in children with diplegic cerebral palsy. The research design was a correlational study. Tasks assessing cognitive function and gross motor abilities were carried out with a sample of 50 children...
April 18, 2017: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/28403842/outcomes-of-autologous-bone-marrow-mononuclear-cells-for-cerebral-palsy-an-open-label-uncontrolled-clinical-trial
#6
Liem Thanh Nguyen, Anh Tuan Nguyen, Chinh Duy Vu, Doan V Ngo, Anh V Bui
BACKGROUND: Stem cell therapy has emerged as a promising method for improving motor function of patients with cerebral palsy. The aim of this study is to assess the safety and effectiveness of autologous bone marrow mononuclear stem cell transplantation in patients with cerebral palsy related to oxygen deprivation. METHODS: An open label uncontrolled clinical trial was carried out at Vinmec International Hospital. The intervention consisted of two administrations of stem cells, the first at baseline and the second 3 months later...
April 12, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28401027/beneficial-effects-of-childhood-selective-dorsal-rhizotomy-in-adulthood
#7
T S Park, Caleb Edwards, Jenny L Liu, Deanna M Walter, Matthew B Dobbs
 Selective dorsal rhizotomy (SDR) has been used to treat children with spastic cerebral palsy (CP) for over three decades. However, little is known about the outcomes of childhood SDR in adults.  Objectives: 1) To study the effects of childhood SDR on the quality of life and ambulatory function in adult life. 2) To determine late side effects of SDR in adults.   Methods: Adults (> 17.9 years) who underwent SDR in childhood (2 - 17.9 years) between 1987 and 2013 were surveyed in 2015. Patients completed a survey, including questions on demographic information, quality of life, health, surgical outcomes, motor function, manual ability, pain, braces/orthotics, post-SDR treatment, living situation, education level, work status, and side effects of SDR...
March 5, 2017: Curēus
https://www.readbyqxmd.com/read/28395573/risk-factors-for-developing-scoliosis-in-cerebral-palsy-a-cross-sectional-descriptive-study
#8
Carlo M Bertoncelli, Federico Solla, Peter R Loughenbury, Athanasios I Tsirikos, Domenico Bertoncelli, Virginie Rampal
This study aims to identify the risk factors leading to the development of severe scoliosis among children with cerebral palsy. A cross-sectional descriptive study of 70 children (aged 12-18 years) with severe spastic and/or dystonic cerebral palsy treated in a single specialist unit is described. Statistical analysis included Fisher exact test and logistic regression analysis to identify risk factors. Severe scoliosis is more likely to occur in patients with intractable epilepsy ( P = .008), poor gross motor functional assessment scores ( P = ...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28393669/serial-casting-as-an-adjunct-to-botulinum-toxin-type-a-treatment-in-children-with-cerebral-palsy-and-spastic-paraparesis-with-scissoring-of-the-lower-extremities
#9
Alper I Dai, Abdullah T Demiryürek
The purpose of this study was to examine whether combination therapy of serial casting and botulinum toxin type A injection can further enhance the effects of botulinum toxin type A in children with cerebral palsy with scissoring of both legs. This study was a prospective and randomized trial. The children were divided into 2 groups, one of which received serial casting after botulinum toxin type A (n = 40), and the other which only received botulinum toxin type A (n = 40). Serial casting started 3 weeks after the botulinum toxin type A...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28393668/evaluation-of-functional-mobility-outcomes-following-electrical-stimulation-in-children-with-spastic-cerebral-palsy
#10
Rupsha Mukhopadhyay, Prasanna K Lenka, Abhishek Biswas, Manjunatha Mahadevappa
This study investigated the clinical feasibility of electrical stimulation in enhancing ankle dorsiflexion of the tibialis anterior muscle to improve mobility in children with spastic cerebral palsy. The intervention group received electrical stimulation therapy for 30 minutes and physiotherapy for another 30 minutes for 5 days a week, up to 12 weeks. Gait parameters, Gross Motor Function Measure, Physiological Cost Index, surface electromyogram, and electroencephalogram (EEG) data were recorded pre- and posttreatment...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28389939/cross-sectional-study-of-urinary-problems-in-adults-with-cerebral-palsy-awareness-and-impact-on-the-quality-of-life
#11
Necmettin Yıldız, Yeşim Akkoç, Murat Ersöz, Berrin Gündüz, Belgin Erhan, Hilal Yesil, Ayşe Nur Bardak, Senay Ozdolap, Hakan Tunç, Kurtulus Koklu, Ebru Alemdaroğlu, Ender Erden, Ulas Sungur, Ozlem Satır, Cagdaş Erdogan, Hakan Alkan
We aimed to assess the functional status, urinary problems, and awareness of these problems in adults with cerebral palsy (CP) and their relationship with the quality of life. One-hundred-seventeen adults with CP (53 women, 64 men) were included in this study. Subjects were asked to fill out a urological questionnaire which dealt with urinary symptoms, awareness of urinary problems, and pharmacological treatment they received. Subjects were also assessed with the Gross Motor Function Classification System (GMFCS), Functional Independence Measures (FIM), Functional Mobility Scale (FMS), and King's Health Questionnaire (KHQ)...
April 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28385185/antibody-responses-to-botulinum-neurotoxin-type-a-of-toxin-treated-spastic-equinus-children-with-cerebral-palsy-a-randomized-clinical-trial-comparing-two-injection-schedules
#12
Minako Oshima, Philip Deitiker, Tandy Hastings-Ison, K Roger Aoki, H Kerr Graham, M Zouhair Atassi
We have conducted a 26-month-long comparative study involving young patients (2-6years old) with a clinical diagnosis of spastic equinus secondary to cerebral palsy who have been treated with BoNT/A (BOTOX®, Allergan) tri-annually or annually. Serum samples were obtained to determine the presence or absence of blocking antibodies (Abs) by a mouse protection assay (MPA) and levels of anti-BoNT/A Abs by radioimmune assay (RIA). HLA DQ alleles were typed using blood samples to determine the possible association of certain HLA type(s) with the disease or with the Ab status...
May 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28379909/the-effect-of-continuous-intrathecal-baclofen-therapy-on-ambulatory-children-with-cerebral-palsy
#13
Blazej Pruszczynski, Julieanne Sees, Robert Hulbert, Chris Church, John Henley, Tim Niiler, Freeman Miller
The effect of a continuous intrathecal infusion of baclofen (CITB) was retrospectively studied in 19 ambulatory children with cerebral palsy (aged 12.4±4.9 years at CITB initiation). The mean clinical follow-up was 5.1±2.4 years and the mean follow-up gait analysis was 2.8±1.9 years. Spastic cerebral palsy diagnosis [14 (74%)] was most frequent. Most patients [11 (58%)] were Gross Motor Function Classification System level III. CITB significantly improved muscle tone and knee flexion at initial contact (P<0...
April 4, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28371738/abnormality-of-standing-posture-improves-in-patients-with-bilateral-spastic-cerebral-palsy-following-lower-limb-surgery
#14
P Buddhdev, N R Fry, R LePage, M Wiley, M Gough, A P Shortland
OBJECTIVES: The degree of abnormality of the gait pattern of children with bilateral spastic cerebral palsy (BSCP) can be reduced by lower limb orthopaedic surgery. However, little attention is paid to the effects of surgery on standing posture. Here, we investigated the abnormality of standing posture in young people with BSCP as well as the effects of surgery on standing posture. METHODS: We have developed an index of standing posture, the Standing Posture Score (SPS), which is similar in composition to the gait profile score (GPS)...
March 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28367118/neurologic-correlates-of-gait-abnormalities-in-cerebral-palsy-implications-for-treatment
#15
REVIEW
Joanne Zhou, Erin E Butler, Jessica Rose
Cerebral palsy (CP) is the most common movement disorder in children. A diagnosis of CP is often made based on abnormal muscle tone or posture, a delay in reaching motor milestones, or the presence of gait abnormalities in young children. Neuroimaging of high-risk neonates and of children diagnosed with CP have identified patterns of neurologic injury associated with CP, however, the neural underpinnings of common gait abnormalities remain largely uncharacterized. Here, we review the nature of the brain injury in CP, as well as the neuromuscular deficits and subsequent gait abnormalities common among children with CP...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28327842/-characteristics-of-patients-with-cerebral-palsy-seen-in-neuropediatric-external-consultation-in-a-peruvian-hospital
#16
Judith R Vila, Ivan O Espinoza, Daniel Guillén, Frine Samalvides
The aim of this study was to describe the neurological consultation and baseline characteristics of children with cerebral palsy (CP). The clinical records of children with CP attending an external consultation of the Neuropediatric department of Hospital Nacional Cayetano Heredia between 2011 and 2012 were assessed in this retrospective descriptive study. A total of 81 children were included: 53.1% were boys. Spastic CP was the most frequent (72.8%), hypoxic-isquemic encephalopathy (28.1%) and cerebral malformations (28...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28322177/prevalence-estimate-of-cerebral-palsy-in-northern-alberta-births-2008-2010
#17
Charlene M T Robertson, M Florencia Ricci, Kathleen O'Grady, Maryam Oskoui, Helly Goez, Jerome Y Yager, John C Andersen
OBJECTIVES: The objectives of this study were to determine prevalence estimates of cerebral palsy (CP) among 5-year-old children in northern Alberta; to provide congenital, gestational age- and birth weight-specific, and postneonatal CP rates; and to describe motor subtypes and function. METHODS: This population-based prevalence estimate study, part of the Canadian Cerebral Palsy Registry, reports confirmed CP diagnoses at age 5 years made by pediatric rehabilitation and child neurology specialists...
March 21, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/28319490/position-between-trunk-and-pelvis-during-gait-depending-on-the-gross-motor-function-classification-system
#18
Jose Manuel Sanz-Mengibar, Natalie Altschuck, Paloma Sanchez-de-Muniain, Christian Bauer, Fernando Santonja-Medina
PURPOSE: To understand whether there is a trunk postural control threshold in the sagittal plane for the transition between the Gross Motor Function Classification System (GMFCS) levels measured with 3-dimensional gait analysis. METHOD: Kinematics from 97 children with spastic bilateral cerebral palsy from spine angles according to Plug-In Gait model (Vicon) were plotted relative to their GMFCS level. RESULTS: Only average and minimum values of the lumbar spine segment correlated with GMFCS levels...
April 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28317070/lumbar-translaminar-fenestration-for-insertion-of-intrathecal-baclofen-catheter-a-novel-technique
#19
Manraj K S Heran, Hisham Al-Shikarchy, Carolyn Chowne
Intrathecal baclofen has long been known to be an efficacious treatment of spasticity in children with cerebral palsy. Test bolus administration is often necessary to ensure patients will benefit from this treatment. The introduction of a intrathecal catheter for test bolus administration can prove challenging in a subset of this population, particularly those who have received surgery with postoperative spinal fusion masses. We outline a novel technique of inserting a spinal catheter for test bolus administration in a patient with a postoperative fusion mass whereby a fenestration is created through the lamina using an osteotomy needle...
March 20, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28300820/children-born-at-32-to-35-weeks-with-birth-asphyxia-and-later-cerebral-palsy-are-different-from-those-born-after-35-weeks
#20
J Garfinkle, P Wintermark, M I Shevell, M Oskoui
OBJECTIVE: The objectives of this study were to (1) establish the proportion of cerebral palsy (CP) that occurs with a history suggestive of birth asphyxia in children born at 32 to 35 weeks and (2) evaluate their characteristics in comparison with children with CP born at ⩾36 weeks with such a history. STUDY DESIGN: Using the Canadian CP Registry, children born at 32 to 35 weeks of gestation with CP with a history suggestive of birth asphyxia were compared with corresponding ⩾36 weeks of gestation children...
March 16, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
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