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spasticity in cp

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https://www.readbyqxmd.com/read/29352624/anesthetic-management-of-two-parturients-with-cerebral-palsy-and-prior-selective-dorsal-rhizotomy
#1
C M Aiudi, E E Sharpe, K W Arendt, J J Pasternak, H P Sviggum
Selective dorsal rhizotomy is a surgical spine procedure used to reduce spasticity in patients with upper motor neuron dysfunction caused by conditions such as cerebral palsy. The optimal anesthetic approach for obstetric patients who have undergone a selective dorsal rhizotomy is unknown. The use and efficacy of neuraxial anesthesia in these patients has not been described. We describe the use of neuraxial anesthesia in two patients with prior selective dorsal rhizotomy. Unless contraindicated for other reasons, a neuraxial anesthetic approach appears to be an effective option in patients with a history of a selective dorsal rhizotomy...
December 15, 2017: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/29351050/hidden-medical-devices-in-the-school-setting-what-the-school-nurse-needs-to-know-about-the-safe-use-of-baclofen-pumps
#2
Barbara Obst, Megan Roesler
One of the "hidden" medical devices in the school setting is the baclofen pump, which is used for the treatment of spasticity. The goals of spasticity treatment are to decrease muscle tone, deformity, and pain in order to maximize function and ease of care for both child and caregiver. The use of an intrathecal baclofen pump, often for children with cerebral palsy, spinal cord injury, brain injury, or stroke, has been effective in spasticity treatment. It is important for school nurses to be aware of the safety implications associated with this type of device...
January 1, 2018: NASN School Nurse
https://www.readbyqxmd.com/read/29341797/visual-dependence-affects-postural-sway-responses-to-continuous-visual-field-motion-in-individuals-with-cerebral-palsy
#3
Yawen Yu, Richard T Lauer, Carole A Tucker, Elizabeth D Thompson, Emily A Keshner
The current study aimed to explore the impact of visual dependence on sensorimotor coupling of postural sway and visual motion in adults and teens with spastic cerebral palsy (CP). We hypothesized that individuals with CP would exhibit greater magnitudes of sway than healthy individuals, and the presence of visual dependence (VD) would produce instability in the direction of visual motion. Participants stood in a virtual environment in which the visual scene remained static or continuously rotated 30 degree/second in pitch-up or pitch-down...
January 17, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29339100/genetic-variation-in-the-dopamine-system-influences-intervention-outcome-in-children-with-cerebral-palsy
#4
Rochellys Diaz Heijtz, Rita Almeida, Ann Christin Eliasson, Hans Forssberg
BACKGROUND: There is large variation in treatment responses in children with cerebral palsy. Experimental and clinical results suggest that dopamine neurotransmission and brain-derived neurotrophic factor (BDNF) signalling are involved in motor learning and plasticity, which are key factors in modern habilitation success. We examined whether naturally occurring variations in dopamine and BDNF genes influenced the treatment outcomes. METHODS: Thirty-three children (18-60months of age) with spastic unilateral cerebral palsy were enrolled in the study...
January 9, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29338493/challenges-of-peroral-endoscopic-myotomy-in-the-treatment-of-distal-esophageal-spasm
#5
Fraukje Anna-Marie Ponds, André J P M Smout, Paul Fockens, Albert J Bredenoord
OBJECTIVE: Distal esophageal spasm (DES) is a rare motility disorder characterized by premature and rapidly propagated contractions of the distal esophagus. Treatment options are limited and often poorly effective. Peroral endoscopic myotomy (POEM) seems an effective and attractive new treatment option for DES. In this case report we describe some of the difficulties that could arise. MATERIALS AND METHODS: A 84-year old man with therapy-refractory DES and complaints of severe dysphagia and chest pain underwent a POEM procedure under general anesthesia...
January 17, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29318610/demographic-and-modifiable-factors-associated-with-knee-contracture-in-children-with-cerebral-palsy
#6
Erika Cloodt, Andreas Rosenblad, Elisabet Rodby-Bousquet
AIM: To identify the prevalence of knee contracture and its association with gross motor function, age, sex, spasticity, and muscle length in children with cerebral palsy (CP). METHOD: Cross-sectional data for passive knee extension were analysed in 3 045 children with CP (1 756 males, 1 289 females; mean age 8y 1mo [SD 3.84]). CP was classified using the Gross Motor Function Classification System (GMFCS) levels I (n=1 330), II (n=508), III (n=280), IV (n=449), and V (n=478)...
January 10, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29309384/toe-walking-a-neurological-perspective-after-referral-from-pediatric-orthopaedic-surgeons
#7
Katherine B Haynes, Robert L Wimberly, Jonathan M VanPelt, Chan-Hee Jo, Anthony I Riccio, Mauricio R Delgado
BACKGROUND: Toe walking (TW) in children is often idiopathic in origin. Our purpose was to determine the incidence of a neurological etiology for TW in patients seen in the neurology clinic after referral from pediatric orthopaedic surgeons. METHODS: We performed an Institutional Review Board approved retrospective review of 174 patients referred to the neurology clinic from orthopaedic surgeons at an academic pediatric tertiary care center between January 2010 and September 2015...
January 5, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29305858/identification-of-a-candidate-enhancer-for-dmrt3-involved-in-spastic-cerebral-palsy-pathogenesis
#8
Naoto Kubota, Toshifumi Yokoyama, Nobuhiko Hoshi, Mikita Suyama
Cerebral palsy (CP) is a major neuronal disease and the most common movement disorder in children. Although environmental factors leading to CP have been greatly investigated, the genetic mechanism underlying CP is not well understood. Here we focused on two clinical reports that characterized a deletion involving the KANK1 gene locus in the 9p24.3 region. One report shows spastic CP and the other shows no spastic CP phenotype. Based on the epigenetic status and evolutionary conservation, we first found a functional genomic element at the noncoding region that was deleted only in patients with spastic CP...
January 3, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29304114/comparison-of-calf-muscle-architecture-between-asian-children-with-spastic-cerebral-palsy-and-typically-developing-peers
#9
Ying Chen, Lu He, Kaishou Xu, Jinling Li, Buyun Guan, Hongmei Tang
OBJECTIVE: To compare the muscle thickness, fascicle length, and pennation angle of the gastrocnemius, soleus, and tibialis anterior between Asian children with spastic cerebral palsy (CP) and typically developing (TD) peers. METHODS: This cross-sectional study involved a total of 72 children with hemiplegic CP (n = 24), and diplegic CP (n = 24) and their TD peers (n = 24). Muscle architecture was measured at rest using ultrasound. Clinical measures included gross motor function and a modified Ashworth scale...
2018: PloS One
https://www.readbyqxmd.com/read/29303031/the-relationship-between-hand-function-and-overlapping-motor-representations-of-the-hands-in-the-contralesional-hemisphere-in-unilateral-spastic-cerebral-palsy
#10
Michelle Marneweck, Hsing-Ching Kuo, Ana R P Smorenburg, Claudio L Ferre, Veronique H Flamand, Disha Gupta, Jason B Carmel, Yannick Bleyenheuft, Andrew M Gordon, Kathleen M Friel
BACKGROUND: In many children with unilateral spastic cerebral palsy (USCP), the corticospinal tract to the affected hand atypically originates in the hemisphere ipsilateral to the affected hand. Such ipsilateral connectivity is on average a predictor of poor hand function. However, there is high variability in hand function in these children, which might be explained by the complexity of motor representations of both hands in the contralesional hemisphere. OBJECTIVE: To measure the link between hand function and the size and excitability of motor representations of both hands, and their overlap, in the contralesional hemisphere of children with USCP...
January 1, 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29301539/development-of-an-inventory-of-goals-using-the-international-classification-of-functioning-disability-and-health-in-a-population-of-non-ambulatory-children-and-adolescents-with-cerebral-palsy-treated-with-botulinum-toxin-a
#11
Linda Nguyen, Ronit Mesterman, Jan Willem Gorter
BACKGROUND: In the management of hypertonicity in children with cerebral palsy (CP), goals should be clearly identified in order to evaluate the effectiveness of botulinum toxin A (BoNT-A) treatment, specifically in non-ambulatory children and adolescents, Gross Motor Function Classification System (GMFCS), level IV or V. A retrospective chart review (Mesterman et al., 2013) identified the need for the development of a set of specific and meaningful goals linked to the International Classification of Functioning, Disability and Health (ICF) for future goal setting and evaluation in this population...
January 4, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29282739/clinical-acceptability-of-the-sense_assess%C3%A2-kids-children-and-youth-perspectives
#12
Susan Taylor, Belinda McLean, Eve Blair, Leeanne Mary Carey, Jane Valentine, Sonya Girdler, Catherine Elliott
BACKGROUND: The sense_assess© kids is a standardised, norm-referenced assessment designed to measure the functional somatosensation capacity of the upper limb of children with cerebral palsy. The objective of the current study was to determine if the sense_assess© kids was clinically acceptable to children and youth. METHODS: A questionnaire was completed by participants following administration of the sense_assess© kids by a trained occupational therapist. Twenty-six children with spastic hemiplegic cerebral palsy (aged 6-15 years six months; mean 10 years eight months; 16 boys) were recruited...
December 28, 2017: Australian Occupational Therapy Journal
https://www.readbyqxmd.com/read/29280208/medial-gastrocnemius-muscle-stiffness-cannot-explain-the-increased-ankle-joint-range-of-motion-following-passive-stretching-in-children-with-cerebral-palsy
#13
Barbara M Kalkman, Lynn Bar-On, Francesco Cenni, Constantinos N Maganaris, Alfie Bass, Gill Holmes, Kaat Desloovere, Gabor J Barton, Thomas D O'Brien
Stretching is often used to increase/maintain joint range of motion (ROM) in children with cerebral palsy (CP) but the effectiveness of these interventions is limited. Therefore, this study aimed to determine the acute changes in muscle-tendon lengthening properties that contribute to increased ROM after a bout of stretching in children with CP. Eleven children with spastic CP (age:12.1(3)y, 5/6 hemiplegia/diplegia, 7/4 GMFCS level I/II) participated in this study. Each child received 3 sets of 5 × 20 s passive, manual static dorsiflexion stretches separated by 30 s rest, and 60 s rest between sets...
December 26, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/29273816/novel-mealtime-duration-measures-reliability-and-preliminary-associations-with-clinical-feeding-and-swallowing-performance-in-self-feeding-children-with-cerebral-palsy
#14
Avinash Mishra, Justine J Sheppard, Cagla Kantarcigil, Andrew M Gordon, Georgia A Malandraki
Purpose: The purpose of this study is to examine (a) the reliability of newly developed measures of mealtime duration and (b) their relationship to clinical feeding/swallowing performance in children with spastic cerebral palsy (SCP). Method: Seventeen self-feeding children (9 boys, 8 girls) with SCP (age range = 5;1 [years;months] to 17;6, Gross Motor Function Classification System range = I-IV) were assessed during mealtimes using the Dysphagia Disorder Survey (DDS; Sheppard, Hochman, & Baer, 2014)...
December 22, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29249551/validation-of-a-clinical-prediction-model-for-the-development-of-neuromuscular-scoliosis-a-multinational-study
#15
Carlo M Bertoncelli, Domenico Bertoncelli, Leonard Elbaum, Michal Latalski, Paola Altamura, Charles Musoff, Virginie Rampal, Federico Solla
BACKGROUND: The objective of this study was to evaluate the performance of a clinical prediction model of neuromuscular scoliosis via external validation. METHODS: We analyzed a series of 120 patients (mean age ± standard deviation, 15.7 ± 1.8 years; range: 12 to 18 years) with cerebral palsy, severe motor disorders, and cognitive impairment with and without neuromuscular scoliosis treated in two specialized units (70 patients from Nice, France, and 50 patients from Lublin, Poland) in a cross-sectional, double-blind study...
November 20, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29231322/-acupuncture-based-on-nourishing-spleen-and-kidney-and-dredging-the-governor-vessel-for-motor-function-and-adl-in-children-with-spastic-cerebral-palsy
#16
Yong Zhao, Zhenhuan Liu, Bingxu Jin
OBJECTIVE: To compare the effects of acupuncture based on nourishing spleen and kidney and dre-dging the governor vessel (GV) combined with rehabilitation and simple rehabilitation for children with spastic cere-bral palsy. METHODS: One hundred and twenty patients were randomly assigned into an observation group and a control group, 60 cases in each one. Physicotherapeutics and hand function training were used in the control group for 3 sessions with 20 d at the interval, 20 times as one session, once a day...
January 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29228927/treatment-with-botulinum-toxin-a-in-a-total-population-of-children-with-cerebral-palsy-a-retrospective-cohort-registry-study
#17
Maria Franzén, Gunnar Hägglund, Ann Alriksson-Schmidt
BACKGROUND: Botulinum toxin A (BTX-A) has been used to reduce spasticity in children with cerebral palsy (CP) for decades. The purpose of this study was to analyze to what extent BTX-A treatment was used to treat spasticity in a total population of children with CP. We investigated 1) the use of BTX-A in relation to age, sex, and Gross Motor Function Classification System (GMFCS) level, 2) the most common muscle groups treated with BTX-A in relation to the same variables, and 3) changes in the proportions of children treated with BTX-A between two time points (2010 and 2015)...
December 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29207820/relationship-between-trunk-control-and-balance-in-children-with-spastic-cerebral-palsy-a-cross-sectional-study
#18
Sivatejaa Panibatla, Vijaya Kumar, Amitesh Narayan
Introduction: Trunk control is impaired in children with Cerebral Palsy (CP) thus influencing their functional balance. However, there is a paucity of literature determining the relationship between trunk control and balance in children with CP. Aim: To find the relationship between trunk control and balance by means of Trunk Control Measurement Scale (TCMS) and Paediatric Balance Scale (PBS). Materials and Methods: Twenty four children {age range 8-14 years, Gross Motor Function Classification System (GMFCS) Level I-III} with spastic CP were recruited and evaluated using TCMS and PBS...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29200489/flexion-deformities-of-the-wrist-and-fingers-in-spastic-cerebral-palsy-a-protocol-of-management
#19
Tarek Hassan Abdelaziz, Shady Samir Elbeshry, Mahmoud Mahran, Ahmad Saeed Aly
Background: Literature is confusing regarding grading and treatment of flexion deformities of wrist and fingers in spastic cerebral palsy (CP). The most established classification is that described by Zancolli; unfortunately, it has its shortcomings which we experienced in the beginning of our approach to manage this rather difficult deformity. We thus modified Zancolli's classification and developed a classification system and treatment protocol. Materials and Methods: Thirty patients with spastic CP were operated upon due to flexion deformity of the wrist and fingers and were included in this study...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29197788/effects-of-antagonistic-and-synergistic-muscles-co-activation-on-mechanics-of-activated-spastic-semitendinosus-in-children-with-cerebral-palsy
#20
Filiz Ateş, Yener Temelli, Can A Yucesoy
OBJECTIVES: Most activities involve co-activation of several muscles and epimuscular myofascial force transmission (EMFT) can affect their mechanics. This can be relevant for spastic muscles of cerebral palsy (CP) patients. Isometric spastic semitendinosus (ST) forces vs. knee angle (KA-FST) data were collected intra-operatively to test the following hypotheses: (i) Inter-antagonistic EMFT elevates FST, (ii) changes the shape of KA-FST characteristics, (iii) reduces the muscle's joint range of force exertion (Range-FST) and (iv) combined inter-antagonistic and synergistic EMFT further changes those effects...
November 30, 2017: Human Movement Science
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