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spasticity in cp

Sylvia A Duraski, Anjum Sayyad
This article details an unreported potential cause of withdrawal symptoms in a patient with cerebral palsy who experienced intrathecal baclofen withdrawal shortly after placement of a baclofen pump with subsequent refill with Gablofen. Initial implantation of the baclofen pump with Lioresal occurred after a successful hospital trial of intrathecal injection via lumbar puncture. However, later, the patient did experience signs and symptoms of baclofen withdrawal after a pump refill was performed with Gablofen...
April 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
Liesbeth F van Vulpen, Sonja de Groot, Eugene A Rameckers, Jules G Becher, Annet J Dallmeijer
BACKGROUND: In children with cerebral palsy (CP), strength training programs to improve walking capacity and participation in activities of daily living are commonly used in clinical practice, despite lacking evidence of its effectiveness. It has been suggested that strength training with high movement velocity could be more effective than traditional resistance training to improve functional abilities such as walking. In a recently published study, we have demonstrated the positive effects of functional high-velocity resistance (power) training on muscle strength and walking capacity in young children with CP...
March 7, 2018: European Journal of Physical and Rehabilitation Medicine
Samuel K van de Velde, Megan Cashin, Ratna Johari, Rachel Blackshaw, Abhay Khot, H Kerr Graham
AIM: The prevalence of severely symptomatic deformities of the first metatarsophalangeal (MTP) joint in adolescents with cerebral palsy (CP) requiring arthrodesis is unknown. Recent literature regarding these deformities is limited. We studied the presentation of severe, symptomatic deformities of the first ray in a large population of children and adolescents with CP and their association with gross motor function, CP subtype, and other musculoskeletal deformities. METHOD: We identified 41 patients with CP and a symptomatic deformity of the first MTP joint, managed by arthrodesis, from a large population based database over a 21-year period...
March 8, 2018: Developmental Medicine and Child Neurology
N Crespo-Eguilaz, P D Dominguez, M Vaquero, J Narbona
AIM: To contribute to neuropsychological profiling of developmental amnesia subsequent to bilateral damage to both hippocampi in early age. SUBJECTS AND METHODS: The total sample of 24 schoolchildren from both sexes is distributed in three groups: perinatal hypoxic-ischaemic encephalopathy and everyday complaints of memory in school age (n = 8); perinatal hypoxic-ischaemic encephalopathy without memory complaints (n = 7); and a group of typically developing (n = 9)...
March 1, 2018: Revista de Neurologia
Ute Deutz, Nicole Heussen, Katharina Weigt-Usinger, Steffen Leiz, Christa Raabe, Tilman Polster, Steinbüchel Daniela, Christine Moll, Thomas Lücke, Ingeborg Krägeloh-Mann, Helmut Hollmann, Martin Häusler
This study investigated the effect of hippotherapy on gross motor function (Gross Motor Function Measure [GMFM]-66, GMFM dimension E and D) and quality of life (Child Health Questionnaire [CHQ 28], KIDSCREEN-27 parental versions) in children with bilateral spastic cerebral palsy. Seventy-three children (age: 9.1 ± 3.3 years; male = 44; GMFCS levels II = 27; III = 17; IV = 29) were randomized to an early ( n  = 35) or late ( n  = 38) treatment group. Data from 66 probands were available for further analysis...
February 27, 2018: Neuropediatrics
L-A Ruiz, M-B Diniz, J-P Loyola-Rodriguez, C-H Habibe, C-C Garrubbo, M-T-B-R Santos
BACKGROUND: Cerebral palsy (CP) is a permanent neurological disorder accompanied by secondary musculoskeletal masticatory disorder, with repercussion on chewing and deglutition functions. In these conditions, the liquids ingestion is compromised resulting in salivary osmolality alteration. The objective of this study was to compare salivary osmolality, caries experience and caries risk between normoreactive individuals and patients with CP. MATERIAL AND METHODS: The participants were 4-20 years old: 52 patients with CP treated at a reference rehabilitation centre (study group, SG), and 52 normoreactive individuals (control group, CG)...
February 24, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
M Murgia, A Bernetti, M Delicata, C Massetti, E M Achilli, M Mangone, F Ioppolo, L Di Sante, V Santilli, G Galeoto, F Agostini, T Venditto
BACKGROUND: Childhood disabilities determine a range of immediate and long-term economic costs that have important implications for the well-being of the child, the family and the society. The Pediatric Evaluation of Disability Inventory (PEDI) measures capability and performance in children aged between 6 months and 7.5 years. It contains three scales: Functional Skills Scales (FSS), Caregiver Assistance Scale (CAS) and Modifications Scale (MS). The present study evaluated the measurement properties of the Italian version of the PEDI (PEDI-I) in patients with spastic cerebral palsy (CP)...
March 2018: Annali di Igiene: Medicina Preventiva e di Comunità
Prashant Jauhari, Pratibha Singhi, Naveen Sankhyan, Prahbhjot Malhi, Sameer Vyas, Niranjan Khandelwal
This study compared the risk factors and clinical and radiologic profile of children with spastic diplegic cerebral palsy born at term (≥37 weeks) with those born preterm. Children (2-14 years) with cerebral palsy meeting the study criteria for spastic diplegia were enrolled. Antecedent risk factors, clinical profile, and magnetic resonance imaging (MRI) findings were recorded. Spasticity, functional ability, intellectual ability, and social quotient were assessed using standard scales. Ninety-three children met the study inclusion criteria (45 term, 48 preterm)...
January 1, 2018: Journal of Child Neurology
Jarred G Gillett, Glen A Lichtwark, Roslyn N Boyd, Lee A Barber
OBJECTIVE: To investigate the relationship between lower limb muscle strength, passive muscle properties and functional capacity outcomes in adults with cerebral palsy (CP). DESIGN: Cross-sectional study. SETTING: Tertiary institution biomechanics laboratory. PARTICIPANTS: Sample of 33 adults with spastic-type CP with a mean age of 25 (range, 15-51) years; mean ± SD body mass 70.15 ± 21.35 kg; Gross Motor Function Classification System (GMFCS) level I n=20, level II n=13...
February 10, 2018: Archives of Physical Medicine and Rehabilitation
Geoffroy Saussez, Marie Van Laethem, Yannick Bleyenheuft
Recently, an intensive bimanual intervention using sensory enriched materials resulted in improved tactile function in children with unilateral spastic cerebral palsy (USCP), raising the question of whether the observed tactile function improvement was due to the sensory enriched environment or the bimanual intervention per se. The present study investigates whether a bimanual intensive intervention improves tactile function. Nineteen children with USCP received 90 hours of bimanual training without enriched environment...
March 2018: Journal of Child Neurology
Marietta L van der Linden, Sadaf Jahed, Nicola Tennant, Martine H G Verheul
OBJECTIVES: RaceRunning enables athletes with limited or no walking ability to propel themselves independently using a three-wheeled running bike that has a saddle and a chest plate for support but no pedals. For RaceRunning to be included as a Para athletics event, an evidence-based classification system is required. Therefore, the aim of this study was to assess the association between a range of impairment measures and RaceRunning performance. METHODS: The following impairment measures were recorded: lower limb muscle strength assessed using Manual Muscle Testing (MMT), selective voluntary motor control assessed using the Selective Control Assessment of the Lower Extremity (SCALE), spasticity recorded using both the Australian Spasticity Assessment Score (ASAS) and Modified Ashworth Scale (MAS), passive range of motion (ROM) of the lower extremities and the maximum static step length achieved on a stationary bike (MSSL)...
February 5, 2018: Gait & Posture
Anne-Sophie Smilga, Jarred Garfinkle, Pamela Ng, John Andersen, David Buckley, Darcy Fehlings, Adam Kirton, Ellen Wood, Esias van Rensburg, Michael Shevell, Maryam Oskoui
BACKGROUND: The goal of this study was to explore the association between neonatal infection and outcomes in children with cerebral palsy. METHODS: We conducted a retrospective cohort study using the Canadian CP Registry. Neonatal infection was defined as meeting one of the following criteria: (1) septicemia, (2) septic shock, or (3) administration of antibiotics for ≥10 days. Phenotypic profiles of children with cerebral palsy with and without an antecedent neonatal infection were compared...
December 13, 2017: Pediatric Neurology
Francesco Cenni, Simon-Henri Schless, Lynn Bar-On, Erwin Aertbeliën, Herman Bruyninckx, Britta Hanssen, Kaat Desloovere
BACKGROUND AND OBJECTIVE: 3D freehand Ultrasonography is a medical imaging technique that can be used to measure muscle and tendon morphological and structural properties, including volume, lengths and echo-intensity. These properties are clinically relevant in neurological disorders such as spastic cerebral palsy to monitor disease progression and evaluate the effect of treatment. This study presents a methodology for extracting these parameters along with a clinical reliability analysis for the data acquisition and processing...
March 2018: Computer Methods and Programs in Biomedicine
Meredith K Gillespie, Peter Humphreys, Hugh J McMillan, Kym M Boycott
Hereditary spastic paraplegia is a phenotypically and genetically heterogeneous group of neurodegenerative disorders characterized by lower extremity weakness and spasticity. Spastic paraplegia 4 (SPG4), caused by heterozygous mutations in the gene SPAST, typically causes a late-onset, uncomplicated form of hereditary spastic paraplegia in affected individuals. Additional clinical features in SPG4 have been reported on occasion, but no genotype-phenotype correlation has been established. Through targeted clinical testing, we identified 2 unrelated female patients with the same de novo p...
January 1, 2018: Journal of Child Neurology
Griet Dequeker, Anja Van Campenhout, Hilde Feys, Guy Molenaers
AIM: To explore the evolution of self-care and functional mobility after multilevel surgery in children and adolescents with spastic diplegic cerebral palsy and to identify factors affecting these outcomes. METHOD: Thirty-four participants (22 males, 12 females) were evaluated before surgery, and at 2 months, 6 months, 1 year, 18 months, and 2 years after surgery. Self-care was assessed with the Pediatric Evaluation of Disability Inventory Dutch edition. The Mobility Questionnaire47 (MobQues47) and Functional Mobility Scale (FMS) were used to measure functional mobility...
February 8, 2018: Developmental Medicine and Child Neurology
Frank Braatz, Thomas Dreher, Sebastian I Wolf, Mirjam Niklasch
BACKGROUND: Femoral derotation osteotomy (FDO) is the standard treatment for internal rotation gait (IRG) in children with cerebral palsy (CP) although high rates of recurrence have been reported recently. Various factors associated with recurrence could be identified, but no predictor named. RESEARCH QUESTIONS: Does FDO lead to a change of internal transversal hip moments? Are preoperative internal transversal hip moments a predictor for recurrence of IRG? METHODS: 41 children with spastic bilateral CP and 72 limbs that received a FDO (10...
January 26, 2018: Gait & Posture
Renata D'Agostini Nicolini-Panisson, Ana Paula Tedesco, Maira Rech Folle, Márcio Vinicius Fagundes Donadio
OBJECTIVE: To identify selection criteria for selective dorsal rhizotomy (SDR) in cerebral palsy, to analyze the instruments used for evaluation, and to describe the characteristics of physical therapy in postoperative protocols. DATA SOURCES: Integrative review performed in the following databases: SciELO, PEDro, Cochrane Library, and PubMed. The terms in both Portuguese and English for "cerebral palsy", "selective dorsal rhizotomy", and "physical therapy" were used in the search...
January 15, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Ju-Young Heo, Hwa-Kyung Shin
[Purpose] The purpose of this study was to translate the Trunk Control Measurement Scale into a Korean version and to analyze the intra- and inter-rater reliability. [Subjects and Methods] Fifteen children with spastic cerebral palsy and four physical therapists with over 10 years of clinical experience participated in this study. A Korean-American physical therapist translated the trunk control measurement scale from English into a Korean version. Four physical therapists viewed the video data of 15 children and scored each child's trunk control measurement scale performance on seven separate days...
January 2018: Journal of Physical Therapy Science
Zhengxun Li, Ning Zhang, Yang Wang, Songhua Cao, Zheng Huang, Yong Hu
BACKGROUND: Equinus of the ankle is a common deformity in spastic cerebral palsy. Achilles tendon lengthening is one of the effective options for the treatment of equinus deformity. METHODS: In the study, a new stair-shaped Achilles tendon lengthening (ATL) procedure that preserves of the tendon continuity was performed in 28 tendons with equinus deformity (20 patients, mean age=10.5±2.6 years). The results were compared with a group of patients treated with the Z-lengthening procedure...
October 27, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Helga Haberfehlner, Richard T Jaspers, Erich Rutz, Jaap Harlaar, Johannes A van der Sluijs, Melinda M Witbreuk, Kim van Hutten, Jacqueline Romkes, Marie Freslier, Reinald Brunner, Jules G Becher, Huub Maas, Annemieke I Buizer
To improve gait in children with spastic paresis due to cerebral palsy or hereditary spastic paresis, the semitendinosus muscle is frequently lengthened amongst other medial hamstring muscles by orthopaedic surgery. Side effects on gait due to weakening of the hamstring muscles and overcorrections have been reported. How these side effects relate to semitendinosus morphology is unknown. This study assessed the effects of bilateral medial hamstring lengthening as part of single-event multilevel surgery (SEMLS) on (1) knee joint mechanics (2) semitendinosus muscle morphology and (3) gait kinematics...
2018: PloS One
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