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https://www.readbyqxmd.com/read/28927241/physical-activity-maintenance-and-metabolic-risk-in-adolescents
#1
Danilo R Silva, André O Werneck, Paul J Collings, Rômulo A Fernandes, Décio S Barbosa, Enio R V Ronque, Luís B Sardinha, Edilson S Cyrino
Aim: Examine the association between child and adolescent physical activity maintenance categories and metabolic profile in adolescence. Methods: This cross-sectional study was conducted with 1152 adolescents (57.4% female) aged 10-16 years from Londrina, Brazil. Physical activity was self-reported in childhood (7-10 years old, retrospective data) and adolescence through questionnaires. Cardiorespiratory fitness (20 m shuttle-run test), body fat (skinfolds), waist circumference, blood pressure (automatic instrument) and blood variables (fasting glucose, HDL-cholesterol and triglycerides) were measured at adolescence...
August 30, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28926979/mother-s-ipv-child-maltreatment-type-and-the-presence-of-ptsd-in-children-and-adolescents
#2
Maravillas Castro, Mavi Alcántara-López, Antonia Martínez, Visitación Fernández, Julio Sánchez-Meca, Concepción López-Soler
This correlational cross-sectional study was designed to investigate whether the intimate partner violence (IPV) suffered by mothers (physical and psychological maltreatment), child eyewitness of psychological and physical maltreatment suffered by the mother, the neglect suffered by children, and the maltreatment (physical and psychological) directly suffered by children are statistically associated to post-traumatic stress disorder (PTSD) symptoms exhibited by the child. In addition, the prevalence of child PTSD was estimated, as well as the concordance between the PTSD symptoms assessed by the Child PTSD Symptom Scale (CPSS) and the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) criteria for child PTSD...
September 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28926843/the-genetic-basis-of-delayed-puberty
#3
S R Howard, Leo Dunkel
<br>The genetic control of puberty remains an important but mostly unanswered question. Late pubertal timing affects over 2% of adolescents and is associated with adverse health outcomes including short stature, reduced bone mineral density and compromised psychosocial health. Self-limited delayed puberty (DP) is a highly heritable trait, which often segregates in an autosomal dominant pattern; however, its neuroendocrine pathophysiology and genetic regulation remain unclear. Some insights into the genetic mutations that lead to familial DP have come from sequencing genes known to cause GnRH deficiency, most recently via next generation sequencing, and others from large-scale genome wide association studies in the general population...
September 18, 2017: Neuroendocrinology
https://www.readbyqxmd.com/read/28926683/salvage-rates-and-prognostic-factors-after-relapse-in-children-and-adolescents-with-malignant-peripheral-nerve-sheath-tumors
#4
Luca Bergamaschi, Gianni Bisogno, Carla Manzitti, Paolo D'Angelo, Giuseppe Maria Milano, Angela Scagnellato, Mirko Cappelletti, Stefano Chiaravalli, Patrizia Dall'Igna, Rita Alaggio, Antonio Ruggiero, Martina Di Martino, Maria Carmen Affinita, Marta Pierobon, Alberto Garaventa, Michela Casanova, Andrea Ferrari
BACKGROUND: Malignant peripheral nerve sheath tumor (MPNST) is one of the most common nonrhabdomyosarcoma soft tissue sarcomas encountered in pediatric age, and it is generally characterized by poor outcome, particularly for relapsing patients. MATERIALS AND METHODS: This study considered 73 patients <21 years of age with relapsing MPNST observed among 120 patients enrolled in Italian pediatric protocols from 1979 to 2004. With the aim of possibly establishing a risk-adapted stratification, patients' outcome was examined using univariate and multivariate analysis based on clinical features at onset, first-line treatments, clinical findings at the time of first relapse, and second-line treatments...
September 19, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28926482/is-there-an-optimal-time-to-initiate-an-active-rehabilitation-protocol-for-concussion-management-in-children-a-case-series
#5
Danielle M Dobney, Lisa Grilli, Helen Kocilowicz, Christine Beaulieu, Meghan Straub, Debbie Friedman, Isabelle J Gagnon
OBJECTIVE: To estimate the time frame during which initiating an active rehabilitation intervention (aerobic exercise, balance, and sport specific skills) after concussion contributed to improvement in symptoms at follow-up in children and adolescents who are slow to recover (symptoms persisting beyond 2 weeks) from concussion. SETTING: Concussion clinic at a tertiary care pediatric teaching hospital. PARTICIPANTS: A total of 677 children and adolescents with concussion aged 7 to 18 years...
September 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28926479/fatigue-following-traumatic-brain-injury-in-children-and-adolescents-a-longitudinal-follow-up-6-to-12-months-after-injury
#6
Alison Crichton, Vicki Anderson, Ed Oakley, Mardee Greenham, Stephen Hearps, Carmel Delzoppo, Miriam H Beauchamp, James S Hutchison, Anne-Marie Guerguerian, Kathy Boutis, Franz E Babl
BACKGROUND: Longitudinal fatigue data in children suffering from traumatic brain injury (TBI) are lacking. OBJECTIVES: To examine the effects of time postinjury (6-12 months) and injury severity on fatigue after childhood TBI. Secondarily, we compared fatigue 12 months postinjury against published control data. SETTING: Three tertiary children's hospitals across Australia (n = 1) and Canada (n = 2). PARTICIPANTS: Parents (n = 109) of children (mean [M] = 9...
September 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28926364/prevalence-of-severe-obesity-and-its-association-with-elevated-blood-pressure-among-children-and-adolescents-in-shandong-china
#7
Ying-Xiu Zhang, Shu-Rong Wang, Su-Yun Li
BACKGROUND: Childhood obesity has increased markedly during the past decades; however, data on the prevalence of severe obesity in children and adolescents are limited. The present study examined the prevalence of severe obesity and its association with elevated blood pressure (BP) among children and adolescents in Shandong, China. PATIENTS AND METHODS: A total of 44 630 (22 404 boys and 22 226 girls) students aged 7-18 years participated in the study. BMI cut-off points recommended by the International Obesity Task Force were used to define class I-III obesity...
September 18, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28926325/-epidemiology-of-internet-use-by-an-adolescent-population-and-its-relation-with-sleep-habits
#8
Carla Ferreira, Helena Ferreira, Maria João Vieira, Mónica Costeira, Liliana Branco, Ângela Dias, Liliana Macedo
INTRODUCTION: In the last decades, the great technological development increased Internet popularity, emerging the concern about its overuse. The objectives of this study were to assess and characterize Internet use in adolescence, determine Internet addiction and clarify its association with sleep disorders and excessive daytime sleepiness. MATERIAL AND METHODS: It was performed an observational, cross sectional and community-based study. The target were students attending 7th and 8th grades, to whom was applied an online self-report questionnaire to assess sociodemographic features, Internet use, Internet dependence, sleep characteristics and excessive daytime sleepiness...
August 31, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28926303/subgroups-of-adolescent-girls-with-borderline-personality-disorder-symptoms
#9
Claire Slavin-Stewart, Khrista Boylan, Jeffrey D Burke
The aim of this study was to determine whether borderline personality disorder (BPD) can be differentiated from other disorders in a clinical sample of adolescent girls. Participants (N = 75) were grouped based on the pattern of BPD symptom endorsement using a latent class analysis. Four latent classes were identified. The most impaired class endorsed seven BPD symptoms and an average of three comorbid disorders. An intermediate class endorsed three BPD symptoms and had the highest prevalence of PTSD (41.7%)...
September 19, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28926286/training-behavioral-control-in-adolescents-using-a-serious-game
#10
Wouter J Boendermaker, Remco C Veltkamp, Margot Peeters
OBJECTIVE: Risk taking, such as heavy alcohol use, is commonplace among adolescents. Nevertheless, prolonged alcohol use at this age can lead to severe health problems. The goal of this study was to develop and evaluate a serious game training ("The Fling"), aimed at increasing behavioral control in adolescents and thereby helping them to improve control over their alcohol use. The game training was compared to a game placebo and a nongame training version in a randomized controlled trial...
September 19, 2017: Games for Health
https://www.readbyqxmd.com/read/28926121/new-pediatric-percentiles-of-liver-enzyme-serum-levels-alt-ast-ggt-effects-of-age-sex-bmi-and-pubertal-stage
#11
Sarah Bussler, Mandy Vogel, Diana Pietzner, Kristian Harms, Theresa Buzek, Melanie Penke, Norman Händel, Antje Körner, Ulrich Baumann, Wieland Kiess, Gunter Flemming
The present study aims to clarify the effects of sex, age, BMI and puberty on transaminase serum levels in children and adolescents and to provide new age- and sex-related percentiles for alanine aminotransferase (ALT), aspartate aminotransferase (AST) and γ-glutamyltransferase (GGT). Venous blood and anthropometric data were collected from 4,126 cases. Excluded were cases of participants with potential hepatotoxic medication, with evidence of potential illness at the time of blood sampling and non-normal BMI (BMI < 10(th) or > 90(th) )...
September 19, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28926000/the-bdnf-val66met-polymorphism-regulates-glucocorticoid-induced-corticohippocampal-remodeling-and-behavioral-despair
#12
M Notaras, X Du, J Gogos, M van den Buuse, R A Hill
The BDNF Val66Met polymorphism has been associated with sensitivity to stress and affective disorders. We therefore sought to model the inter-causality of these relationships under controlled laboratory conditions. We subjected humanized BDNF Val66Met (hBDNF(Val66Met)) transgenic mice to a history of stress, modeled by chronic late-adolescent corticosterone (CORT) exposure, before evaluating affective-related behavior using the forced-swim test (FST) in adulthood. While hBDNF(Met/Met) mice had a depression-like phenotype in the FST irrespective of CORT, hBDNF(Val/Val) wildtype mice had a resilient phenotype but developed an equally robust depressive-like phenotype following CORT...
September 19, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28925941/cold-atmospheric-plasma-in-the-treatment-of-osteosarcoma
#13
REVIEW
Denis Gümbel, Sander Bekeschus, Nadine Gelbrich, Matthias Napp, Axel Ekkernkamp, Axel Kramer, Matthias B Stope
Human osteosarcoma (OS) is the most common primary malignant bone tumor occurring most commonly in adolescents and young adults. Major improvements in disease-free survival have been achieved by implementing a combination therapy consisting of radical surgical resection of the tumor and systemic multi-agent chemotherapy. However, long-term survival remains poor, so novel targeted therapies to improve outcomes for patients with osteosarcoma remains an area of active research. This includes immunotherapy, photodynamic therapy, or treatment with nanoparticles...
September 19, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28925769/how-to-effectively-design-and-create-a-concept-mobile-application-to-aid-in-the-management-of-type-1-diabetes-in-adolescents
#14
Victoria McCulloch, Sarah Hope, Brian Loranger, Paul Rea
Diabetes is one of the most prevalent chronic health conditions in the world; with a range of diabetes-related mobile applications available to the public to aid in glycaemic control and self-management. Statistically, adherence to medication is extremely low in adolescents with Type 1 Diabetes Mellitus (T1DM), therefore, this paper focuses on the research and design of an interactive and educational concept mobile application aimed at early to mid-adolescents to aid in their understanding of T1DM. As visual elements are an essential part of the design, this research outlines how visual components were designed specifically for adolescents with T1DM...
September 19, 2017: Journal of Visual Communication in Medicine
https://www.readbyqxmd.com/read/28925643/screening-for-syphilis-infection-in-nonpregnant-adults-and-adolescents
#15
Tina Fan, Amy Rogers
No abstract text is available yet for this article.
September 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/28925577/sex-and-maturity-status-affected-the-validity-of-a-submaximal-cycle-test-in-adolescents
#16
Frida Björkman, Andrea Eggers, Adam Stenman, Tony Bohman, Björn Ekblom, Örjan Ekblom
AIM: This study assessed the validity and reliability of the Ekblom-Bak (EB) submaximal cycle test in adolescents and identified any sex or maturity-related factors for prediction errors. METHODS: We recruited 50 healthy subjects through a public announcement in Stockholm, Sweden, in 2016. The 27 boys and 23 girls were aged 10-15 years and in Tanner stages I-IV. They performed an EB test and incremental treadmill running test for direct measurement of maximal oxygen uptake (VO2 max)...
September 19, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28925411/birthweight-and-cardiometabolic-risk-patterns-in-multiracial-children
#17
D Sun, T Wang, Y Heianza, T Huang, X Shang, J Lv, S Li, E Harville, W Chen, V Fonseca, L Qi
BACKGROUND/OBJECTIVES: Prenatal growth, which is widely marked by birthweight, may have a pivotal role in affecting the lifelong risk of cardiometabolic disorders; however, comprehensive evaluation of its relations with childhood cardiometabolic risk patterns and the ethnic and gender disparities in national representative populations is still lacking. The aim of this study was to evaluate the associations between birthweight and comprehensive patterns of cardiometabolic risk in a nationally representative sample of children and adolescents...
August 14, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28925350/beliefs-in-social-inclusion-invariance-in-associations-among-hope-dysfunctional-attitudes-and-social-inclusion-across-adolescence-and-young-adulthood
#18
Clio Berry, Kathryn Greenwood
Social disability in youth is an important precursor of long-term social and mental health problems. Social inclusion is a key policy driver and fits well within a new paradigm of health and well-being rather than illness-oriented services, yet little is known about social inclusion and its facilitators for "healthy" young people. We present a novel exploratory structural analysis of social inclusion using measures from 387 14- to 36-year-olds. Our model represents social inclusion as comprising social activity and community belonging, with both domains predicted by hopeful and dysfunctional self-beliefs but hopefulness more uniquely predicting social inclusion in adolescence...
September 19, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28925345/differences-in-the-prevalence-of-overweight-and-obesity-in-5-to-14-year-old-children-in-krak%C3%A3-w-poland-using-three-national-bmi-cut-offs
#19
Renata Woźniacka, Aneta Bac, Małgorzata Kowal, Stanisław Matusik
The problem of overweight and obesity in children and adolescents has been noted in many different countries. The aim of this study was to evaluate the differences in the percentage occurrence of overweight and obesity in Polish children depending on the criteria used, and to evaluate the usefulness of the Polish national database. The study sample comprised 3405 children aged 5-14 years (1674 girls and 1731 boys) from the city of Kraków, Poland, in 2009-2010. The BMI of each child was calculated and classified as overweight or obese according to three different reference BMI cut-offs: the International Obesity Task Force (IOTF), the Centers for Disease Control and Prevention (CDC) and the Polish 2010 standard...
September 19, 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/28925343/developmental-pathways-from-maltreatment-to-risk-behavior-sexual-behavior-as-a-catalyst
#20
Sonya Negriff
Although delinquency, substance use, and sexual activity are established to be highly intercorrelated, the extant research provides minimal evidence in support of one particular sequence of risk behavior or on the cascade effects from maltreatment. The present study tested a longitudinal model incorporating maltreatment, deviant peers, sexual behavior, delinquency, and substance use to elucidate the sequential pathway(s) from maltreatment to each specific risk behavior throughout adolescence. Data came from a longitudinal study on the effects of maltreatment on adolescent development (N = 454) with four study assessments from early (Time 1 M age = 10...
September 19, 2017: Development and Psychopathology
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