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https://www.readbyqxmd.com/read/29340883/associations-of-coffee-consumption-and-caffeine-intake-with-mammographic-breast-density
#1
Lusine Yaghjyan, Graham Colditz, Bernard Rosner, Aleksandra Gasparova, Rulla M Tamimi
PURPOSE: Previous studies suggest that coffee and caffeine intake may be associated with reduced breast cancer risk. We investigated the association of coffee and caffeine intake with mammographic breast density by woman's menopausal status and, in postmenopausal women, by hormone therapy (HT). METHODS: This study included 4130 cancer-free women within the Nurses' Health Study and Nurses' Health Study II cohorts. Percent breast density (PD) was measured from digitized film mammograms using a computer-assisted thresholding technique and square root-transformed for the analysis...
January 17, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29336121/inter-and-intra-operator-reliability-in-patient-specific-template-positioning-for-total-hip-arthroplasty-a-cadaver-study
#2
Manuel Krämer, Lüder A Kahrs, Karl-Ingo Friese, Christian von Falck, Christof Hurschler
BACKGROUND: The implantation of the acetabular cup essentially determines the clinical outcome of total hip arthroplasty. To address this issue, the aim of this study was to build patient-specific instruments (PSIs) with various reference surfaces, followed by in vitro investigations to examine the inter- and intra-operator reliability as well as the overall precision of these patient-specific templates. METHODS: Seven human hemi-pelvis specimens were used for this study...
January 15, 2018: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/29334416/investigating-causal-associations-between-use-of-nicotine-alcohol-caffeine-and-cannabis-a-two-sample-bidirectional-mendelian-randomization-study
#3
Karin J H Verweij, Jorien L Treur, Jacqueline M Vink
BACKGROUND AND AIMS: Epidemiological studies consistently show co-occurrence of use of different addictive substances. Whether these associations are causal or due to overlapping underlying influences remains an important question in addiction research. Methodological advances have made it possible to use published genetic associations to infer causal relationships between phenotypes. In this exploratory study, we used Mendelian randomization (MR) to examine the causality of well-established associations between nicotine, alcohol, caffeine, and cannabis use...
January 15, 2018: Addiction
https://www.readbyqxmd.com/read/29322899/is-the-pelvis-stable-during-supine-total-hip-arthroplasty
#4
S M Shah, W L Walter, J Ngo
Intra- operative changes in pelvic position during total hip arthroplasty (THA) can affect acetabular orientation. We evaluated these changes during supine THA using a proprietary mobile application called PelvicTracker. Twenty- two patients undergoing THA using direct anterior approach were included in the study. In the sagittal plane, the pelvis was extended (anterior tilt) as compared to the start of surgery in 19/ 22 hips at the time of cup implantation (mean extension: 3.1°; range: 1°-6°). In the transverse plane, the pelvis was rolled to the opposite side of surgery in 12 hips (mean roll: 2...
March 2017: Acta Orthopaedica Belgica
https://www.readbyqxmd.com/read/29320923/the-effect-of-seated-pelvic-tilt-on-posterior-edge-loading-in-total-hip-arthroplasty-a-finite-element-investigation
#5
Jim Pierrepont, Long Yang, Jevan Arulampalam, Catherine Stambouzou, Brad Miles, Qing Li
Edge-loading of a ceramic-on-ceramic total hip replacement can lead to reproducible squeaking and revision. A patient's functional acetabular cup orientation, driven by their pelvic tilt, has been shown to be a significant factor in squeaking during hip flexion. The aim of this study was to investigate the effect of seated pelvic tilt on the contact mechanics at the ceramic bearing surface. A finite element model of a ceramic-on-ceramic total hip replacement was created. The cup was orientated at 40° inclination and 15° anteversion relative to the anterior pelvic plane...
January 1, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29313319/early-experience-with-a-tapered-titanium-porous-plasma-sprayed-stem-with-updated-design
#6
Antonio G Manocchio, Keith R Berend, Michael J Morris, Joanne B Adams, Adolph V Lombardi
INTRODUCTION: The Taperloc® Complete femoral stem (Zimmer Biomet, Warsaw, Indiana) builds on the widespread clinical success of the original Taperloc design used since 1982. Enhancements to the Complete design include a lowered caput-collum-diaphyseal (CCD) angle from 138° to 133° for improved offset, optimized neck taper with polished neck flats to increase range of motion, reduced distal geometry to improve proximal canal fill, and gradual off-loading that is the goal of tapered geometry...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29312852/acetabular-cup-version-modelling-and-its-clinical-applying-on-plain-radiograms
#7
Anton Denisov, Stanislav Bilyk, Anton Kovalenko
AIM: To measure the sensitivity and specificity of the cup version assessment by using only anteroposterior hip and pelvis views, evaluate the incidence of inadequate cup version in patients with repeated dislocations after total hip arthroplasty (THA). METHODS: Radiographic retrospective analysis of 2 groups of patients, with follow up of 6-60 mo, after undergoing primary THA. First group of 32 patients (20 female, 12 male) with unilateral THA (32 hips) required early revision arthroplasty for reasons of dislocation...
December 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29305289/prediction-models-to-improve-the-diagnostic-value-of-plain-radiographs-in-children-with-complete-discoid-lateral-meniscus
#8
Yong-Beom Park, Chul-Won Ha, Jae Won Jang, Manyoung Kim, Han-Jun Lee, Yong-Geun Park
PURPOSE: To develop prediction models to improve the diagnostic utility of plain radiographs for the diagnosis of complete discoid lateral meniscus by combining previously reported radiographic findings. METHODS: Patients ages 5 to 16 years with complete discoid lateral meniscus confirmed by arthroscopy or magnetic resonance imaging were included. Patients with insufficient radiographs were excluded. Normal control subjects were randomly sampled by age and sex matching...
January 2, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29284954/effect-of-transcutaneous-electrical-nerve-stimulation-on-parotid-saliva-flow-in-patients-with-hyposalivation
#9
P Venkatalakshmi Aparna, S Leena Sankari, M Deivanayagi, A Priyadharshini, C K Vishnupriya, B Niveditha
Context: In recent days, we have come across an increase incidence of dry mouth as a side effects of drugs and in order to bring an awareness about a simple non- invasive method to increase the salivary flow, we have used TENS which in many way is beneficial to patients with metabolic disorders. Aims and Objectives: The aim is to assess the effectiveness of transcutaneous electrical nerve stimulation on salivary gland function in patients with hyposalivation. Subjects and Methods: The present study included total of 25 subjects with complaint of hyposalivation...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29276116/effect-of-pelvic-tilt-and-rotation-on-cup-orientation-in-both-supine-and-standing-positions
#10
Hohyun Yun, William S Murphy, Daniel M Ward, Guoyan Zheng, Brett Hayden, Stephen B Murphy
BACKGROUND: The purpose of this study is to analyze the effect of pelvic tilt and rotation on radiographic measurement of cup orientation. METHODS: A total of 68 patients (79 hips) were included in this study. The patients had a computed tomography study and approximately 3 months of postoperative standing anteroposterior pelvic radiographs in both supine and standing positions. We used 2-dimensional (2D)/3-dimensional (3D) matching to measure pelvic tilt and rotation, and cup orientation...
December 6, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29275431/influence-of-femoral-bowing-on-range-of-motion-after-total-hip-arthroplasty
#11
Keisuke Akiyama, Takaaki Shibuya
PURPOSE: The influence of physiologic femoral bowing on range of motion (ROM) after total hip arthroplasty (THA) remains unknown. The purpose of this study was to investigate the morphology of the femur in patients who underwent THA, and to analyze the influence of femoral bowing on ROM due to implant impingement after THA. METHODS: The ROM was calculated from 100 hips in 90 patients who underwent THA using computed tomography data with a 3D dynamic analysis software...
December 23, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29273288/cementation-of-a-dual-mobility-construct-in-recurrently-dislocating-and-high-risk-patients-undergoing-revision-total-arthroplasty
#12
Brian P Chalmers, Cameron K Ledford, Michael J Taunton, Rafael J Sierra, David G Lewallen, Robert T Trousdale
BACKGROUND: Recurrent instability remains a challenge after revision total hip arthroplasty (THA). We report the outcomes of cementing a cementless dual mobility (DM) component into a stable acetabular shell for the treatment and/or prevention of instability in revision THA. METHODS: Eighteen patients (18 THAs) undergoing revision THA with a specific monoblock DM construct cemented into a new acetabular component or an existing well-fixed component from 2011 to 2014 were retrospectively reviewed...
December 6, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29260496/evaluation-of-cntnap2-gene-rs2107856-polymorphism-in-turkish-population-with-pseudoexfoliation-syndrome
#13
Irmak Karaca, Suzan Guven Yilmaz, Melis Palamar, Huseyin Onay, Bilcag Akgun, Burcu Aytacoglu, Ayca Aykut, Feristah Ferda Ozkinay
PURPOSE: To investigate rs2107856 single-nucleotide polymorphism (SNP) of CNTNAP2 gene in Turkish population with pseudoexfoliation and to correlate clinical characteristics with the genotypic profile. MATERIALS AND METHODS: Forty-three patients with pseudoexfoliation syndrome (PXS), 46 patients with pseudoexfoliation glaucoma (PXG) and 99 healthy controls were enrolled. Comprehensive ophthalmological examination, central corneal thickness measurement and retinal nerve fiber layer thickness analysis of the peripapillary area were performed...
December 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29260384/predictive-factors-for-metal-ion-levels-in-metal-on-metal-total-hip-arthroplasty
#14
Maximilian F Kasparek, Lisa Renner, Martin Faschingbauer, Wenzel Waldstein, Michael Weber, Friedrich Boettner
INTRODUCTION: Although metal-on-metal (MoM) total hip arthroplasty (THA) and hip resurfacings (HR) have similar bearing surfaces and comparable wear rates, metal ion levels and risk of failure are higher for MoM-THA. The mechanism behind the increased metal ion levels in large head MoM-THA is not completely understood. The current study aims to identify predictive factors for increased metal ion levels in unilateral and bilateral large head MoM-THA. MATERIALS AND METHODS: 99 Birmingham modular MoM-THA in 87 patients with metal ion levels at least 36 months after index procedure were analyzed...
December 19, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29260044/isolated-presumed-optic-nerve-gumma-a-rare-presentation-of-neurosyphilis
#15
Nailyn Rasool, James A Stefater, Dean Eliott, Dean M Cestari
Purpose: The incidence of syphilitic infections continues to rise and represents a major public health concern, particularly in patients co-infected with human immunodeficiency virus (HIV). The infection has a multitude of clinical presentations and is often referred to as the 'great imitator.' We present a rare case of an isolated presumed syphilitic optic nerve gumma and characterize it using newer imaging modalities. Observations: A 36-year-old HIV-positive man, compliant with treatment, presented with a five day history of decreased vision in the left eye...
June 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29259849/genome-wide-characterization-and-expression-profiling-of-nac-transcription-factor-genes-under-abiotic-stresses-in-radish-raphanus-sativus-l
#16
Bernard Kinuthia Karanja, Liang Xu, Yan Wang, Everlyne M'mbone Muleke, Bashir Mohammed Jabir, Yang Xie, Xianwen Zhu, Wanwan Cheng, Liwang Liu
NAC (NAM, no apical meristem; ATAF, Arabidopsis transcription activation factor and CUC, cup-shaped cotyledon) proteins are among the largest transcription factor (TF) families playing fundamental biological processes, including cell expansion and differentiation, and hormone signaling in response to biotic and abiotic stresses. In this study, 172 RsNACs comprising 17 membrane-bound members were identified from the whole radish genome. In total, 98 RsNAC genes were non-uniformly distributed across the nine radish chromosomes...
2017: PeerJ
https://www.readbyqxmd.com/read/29250498/perioperative-comparison-of-hip-arthroplasty-using-the-direct-anterior-approach-with-the-posterolateral-approach
#17
Sang Hong Lee, Sin Wook Kang, Suenghwan Jo
Purpose: The aim of the current study is to report the advantage and disadvantage of total hip arthroplasty performed in direct anterior approach (DAA) by comparing it to the posterolateral approach (PLA). Materials and Methods: Twenty-five hip arthroplasty done in DAA (12 total hip arthroplasty [THA] and 13 bipolar hemiarthroplasty [BHA]) were compared with the same number done in PLA (13 THA and 12 BHA). Intraoperative assessments including operation time, anesthetic time, bleeding amount were recorded with intraoperative complications...
December 2017: Hip & Pelvis
https://www.readbyqxmd.com/read/29250495/results-of-total-hip-arthroplasty-with-36-mm-metallic-femoral-heads-on-1st-generation-highly-cross-linked-polyethylene-as-a-bearing-surface-in-less-than-forty-year-old-patients-minimum-ten-year-results
#18
Won Kee Choi, Jae Jung Kim, Myung-Rae Cho
Purpose: We evaluated long-term clinical and radiographic results in patients underwent primary total hip arthroplasty (THA) using 36-mm metallic femoral head and 1st generation highly cross-linked polyethylene among patients aged 40 years and less, with minimum 10 years follow-up. Materials and Methods: We retrospectively reviewed 20 hips underwent primary THA by one hip surgeon using 36-mm femoral head and 1st generation highly cross-linked polyethylene from 2004 to 2006...
December 2017: Hip & Pelvis
https://www.readbyqxmd.com/read/29236207/factors-related-to-disagreement-in-implant-size-between-preoperative-ct-based-planning-and-the-actual-implants-used-intraoperatively-for-total-hip-arthroplasty
#19
Takeshi Ogawa, Masaki Takao, Takashi Sakai, Nobuhiko Sugano
PURPOSE: In total hip arthroplasty, prediction of the optimal implant size is important in order to prevent perioperative complications. However, it is not easy to achieve complete agreement between the planned size and the actual size required appropriate implant fit. No previous report has adequately discussed the factors related to mismatch between predicted and actual implant sizes. The purpose was to report the results of a single surgeon case series of patients undergoing THA using computed tomography (CT)-based templating and the possible factors related to implant size mismatch...
December 13, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29202986/arthrodesis-of-the-first-metatarsophalangeal-joint-a-biomechanical-comparison-of-four-fixation-techniques
#20
Ella Harris, Paul Moroney, Yves Tourné
BACKGROUND: Arthrodesis of the first metatarsophalangeal joint is a commonly performed orthopaedic procedure. The optimum method of fixation and joint surface preparation has yet to be determined. METHODS: This study compared four fixation techniques: Biomechanical grade sawbones were used. The dorsal plate used was a titanium, anatomically contoured locked plate. Testing was performed using an Instron machine applying force from the plantar aspect of the fused joint...
December 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
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