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https://www.readbyqxmd.com/read/28108376/emodin-a-compound-with-putative-antidiabetic-potential-deteriorates-glucose-tolerance-in-rodents
#1
Sameer Abu Eid, Michael Adams, Thomas Scherer, Héctor Torres-Gómez, Martina Theresa Hackl, Mairam Kaplanian, Rainer Riedl, Anton Luger, Clemens Fürnsinn
Emodin is found in remedies from Traditional Chinese Medicine. Since antihyperglycaemic action was observed in rodents, non-scientific sources advertise emodin intake as a natural cure for diabetes. Emodin was admixed to high fat-food of obese mice at two doses (2 and 5g/kg; daily emodin uptake 103 and 229mg/kg). Comparison was made to ad libitum fed and to food restricted control groups, the latter showing the same weight gain as the corresponding emodin-treated groups. Emodin blunted food intake by 6% and 20% for the low and high dose, which was accompanied by proportionate reductions in weight gain...
January 17, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28103491/chemically-activated-carbon-from-lignocellulosic-wastes-for-heavy-metal-wastewater-remediation-effect-of-activation-conditions
#2
Arunima Nayak, Brij Bhushan, Vartika Gupta, P Sharma
Chemical activation is known to induce specific surface features of porosity and functionality which play a definite role in enhancing the adsorptive potential of the developed activated carbons. Different conditions of temperature, time, reagent type and impregnation ratio were applied on sawdust precursor and their effect on the physical, surface chemical features and finally on the adsorption potential of the developed activated carbons were analysed. Under activation conditions of 600°C, 1hr, 1:0.5 ratio, ZnCl2 impregnated carbon (CASD_ZnCl2) resulted in microporosity while KOH impregnation (CASD_KOH) yielded a carbon having a wider pore size distribution...
January 10, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28101613/estimation-of-anaerobic-debromination-rate-constants-of-pbde-pathways-using-an-anaerobic-dehalogenation-model
#3
Filiz Karakas, Ipek Imamoglu
This study aims to estimate anaerobic debromination rate constants (km) of PBDE pathways using previously reported laboratory soil data. km values of pathways are estimated by modifying a previously developed model as Anaerobic Dehalogenation Model. Debromination activities published in the literature in terms of bromine substitutions as well as specific microorganisms and their combinations are used for identification of pathways. The range of estimated km values is between 0.0003 and 0.0241 d(-1). The median and maximum of km values are found to be comparable to the few available biologically confirmed rate constants published in the literature...
January 19, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28088549/redistribution-of-elements-between-wastes-and-organic-bearing-material-in-the-dispersion-train-of-gold-bearing-sulfide-tailings-part-i-geochemistry-and-mineralogy
#4
B Yu Saryg-Ool, I N Myagkaya, I S Kirichenko, M A Gustaytis, O V Shuvaeva, S M Zhmodik, E V Lazareva
Migration and redistribution of elements during prolonged interaction of cyanide wastes with the underlying natural organic-bearing material have been studied in two ~40cm deep cores that sample primary ores and their weathering profile (wastes I and II, respectively) in the dispersion train of gold-bearing sulfide tailings in Siberia. Analytical results of SR-XRF, whole-rock XRF, AAS, CHNS, and SEM measurements of core samples show high K, Sr, Ti, and Fe enrichments and correlation of P2O5 and Mn with LOI and Corg...
January 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28078251/a-review-of-fermented-foods-with-beneficial-effects-on-brain-and-cognitive-function
#5
REVIEW
Binna Kim, Veronica Minsu Hong, Jeongwon Yang, Heejung Hyun, Jooyeon Jamie Im, Jaeuk Hwang, Sujung Yoon, Jieun E Kim
Around the world, fermentation of foods has been adopted over many generations, primarily due to their commercial significance with enriched flavors and high-profile nutrients. The increasing application of fermented foods is further promoted by recent evidence on their health benefits, beyond the traditionally recognized effects on the digestive system. With recent advances in the understanding of gut-brain interactions, there have also been reports suggesting the fermented food's efficacy, particularly for cognitive function improvements...
December 2016: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/28069731/an-old-remedy-for-a-new-problem-identification-of-ooencyrtus-kuvanae-hymenoptera-encyrtidae-an-egg-parasitoid-of-lycorma-delicatula-hemiptera-fulgoridae-in-north-america
#6
Houping Liu, Jason Mottern
Spotted Lanternfly, Lycorma delicatula (White) is a recently introduced pest of Tree-of-Heaven, Ailanthus altissima (Mill.) Swingle in North America. Natural enemy surveys for this pest in Pennsylvania in 2016 recovered an encyrtid egg parasitoid from both field collections and laboratory rearing of field-collected L. delicatula egg masses. Both molecular and morphological data confirm that the egg parasitoids are Ooencyrtus kuvanae (Howard) (Hymenoptera: Encyrtidae). Ooencyrtus kuvanae (Howard) is primarily an egg parasitoid of gypsy moth, Lymantria dispar (L...
January 9, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/28069300/response-of-microbial-communities-colonizing-salt-marsh-plants-rhizosphere-to-copper-oxide-nanoparticles-contamination-and-its-implications-for-phytoremediation-processes
#7
Joana P Fernandes, C Marisa R Almeida, Federico Andreotti, Leandro Barros, Tânia Almeida, Ana P Mucha
This study aimed to investigate Cu oxide nanoparticles (CuO NP) effect on microbial communities associated with salt marsh plants (Halimione portulacoides and Pragmites australis) rhizosphere and its implications for phytoremediation processes. Experiments were conducted, under controlled conditions, over one week. Rhizosediment soaked in the respective elutriate (a simplified natural medium) with or without plants, was doped with CuO NP or with Cu in ionic form. Microbial community in rhizosediments was characterized in terms of abundance (by DAPI) and structure (by ARISA)...
January 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28056930/anti-diarrheal-and-anti-inflammatory-activities-of-aqueous-extract-of-the-aerial-part-of-rubia-cordifolia
#8
Xue-Peng Gong, Yuan-Yuan Sun, Wei Chen, Xia Guo, Jian-Kun Guan, Dong-Yan Li, Guang Du
BACKGROUND: In Shaanxi province, China, the aqueous extract of Rubia cordifolia's aerial part (AERCAP) is traditionally used to manage diarrhea. However, there is no scientific evidence to verify the safety and efficacy of its use. The aim of this study was to investigate the anti-diarrheal and anti-inflammatory effects of AERCAP by using a rodent model. METHODS: The anti-diarrheal effects were studied by senna leaf-induced diarrheal and intestinal transit experiments in mice...
January 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28053889/antioxidant-antiglycation-and-insulinotrophic-properties-of-coccinia-grandis-l-in%C3%A2-vitro-possible-role-in-prevention-of-diabetic-complications
#9
Packirisamy Meenatchi, Ayyakkanuu Purushothaman, Sivaprakasam Maneemegalai
In an attempt to develop Complementary and Alternative Medicine (CAM) for the treatment of diabetes and related complications, the antidiabetic potential of the mature unripe fruits of Coccinia grandis (CGF) was evaluated. Oxidative stress and glycation plays an important role in manifesting of diabetes and vascular complications. Agents with antioxidant and antiglycation properties may retard these pathological alterations. In this study, the edible plant Coccinia grandis was assessed for in vitro estimation of antioxidant and antiglycation potential and its insulinotrophic properties in RINm5F cells...
January 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28052018/targeting-micrornas-a-new-action-mechanism-of-natural-compounds
#10
REVIEW
Qian Lin, Leina Ma, Zhantao Liu, Zhihong Yang, Jin Wang, Jia Liu, Guohui Jiang
Unlike genetics, epigenetics involves the modification of genome without changes in DNA sequences, including DNA methylation, histone modification, chromatin remodeling and noncoding RNA regulation. MicroRNA (miRNA), a member of noncoding RNAs superfamily, participates in RNA interference through a unique mechanism. Currently, microRNAs have been found to be regulated by some natural compounds. Through altering the expression of miRNAs and influencing the downstream signaling pathways or target genes, several natural compounds exhibit its bioactivity in the prevention, diagnosis, therapy, prognosis and drug resistance of human diseases, such as cancer...
December 30, 2016: Oncotarget
https://www.readbyqxmd.com/read/28050502/antibacterial-effect-of-aloe-vera-gel-against-oral-pathogens-an-in-vitro-study
#11
Supreet Jain, Nirav Rathod, Ravleen Nagi, Jaideep Sur, Afshan Laheji, Naveen Gupta, Priyanka Agrawal, Swati Prasad
INTRODUCTION: Natural herbal remedies have shown promising anti-microbial property and fewer side effects compared to synthetic anti-microbial therapy. Aloe Vera is a medicinal plant used for management of various infections since ancient times as it has anti-inflammatory, anti-microbial, and immune-boosting properties. AIM: The aim of the present study was to determine the anti-microbial and inhibitory activities of various concentration of Aloe Vera Gel (AVG) against oral pathogenic bacteria...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28043492/antimycobacterial-activity-assessment-of-three-ethnobotanical-plants-against-mycobacterium-tuberculosis-an-in-vitro-study
#12
Mohammad Arjomandzadegan, Navid Emami, Ghasem Habibi, Ali Asghar Farazi, Manijeh Kahbazi, Hossein Sarmadian, Mansooreh Jabbari, Hossein Hosseini, Mona Ramezani
OBJECTIVE/BACKGROUND: Resistances to herbal medicines are still not defined and finding natural remedies against drug resistant Mycobacterium tuberculosis (MTB) has research priority. The antimycobacterial susceptibility method for herbal extracts is unclearly defined and there is no standard method for assessment of the materials against bacteria. In the present study, time kill of three medicinal plants was determined against MTB. METHODS: The clinical isolate of MTB from a patient who harbored confirmed tuberculosis was used in the study...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28040821/over-the-counter-and-natural-remedies-for-onychomycosis-do-they-really-work
#13
Pierre Halteh, Richard K Scher, Shari R Lipner
Onychomycosis is a fungal infection of the nail unit that may lead to dystrophy and disfigurement over time. It accounts for up to 50% of all nail conditions, with toenails affected more commonly than fingernails. Onychomycosis may affect quality of life and increase the prevalence and severity of foot ulcers in patients with diabetes. Available oral agents approved by the US Food and Drug Administration (FDA) for the treatment of onychomycosis include terbinafine and itraconazole, which have demonstrated good efficacy but are associated with the risk of systemic side effects and drug-drug interactions...
November 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28040555/juncus-spp-the-helophyte-for-all-phyto-remediation-purposes
#14
Evdokia Syranidou, Stavros Christofilopoulos, Nicolas Kalogerakis
Helophytic plants contribute significantly to the remediation of ecosystems through a wide range of physiological or biochemical mechanisms including the role of endophytic bacteria. This review highlights the services provided by Juncus spp. wetland plants, from phytoremediation of soils and groundwater with heavy metals and/or organics to municipal or industrial wastewater treatment in constructed wetlands. The data presented also provide information on the efficiency of specific Juncus spp. in response to various metals and organic compounds, in an effort to exploit the natural capabilities of autochthonous over exotic species in phytoremediation strategies...
December 28, 2016: New Biotechnology
https://www.readbyqxmd.com/read/28034659/toxins-and-pharmacologically-active-compounds-from-species-of-the-family-bufonidae-amphibia-anura
#15
REVIEW
Candelario Rodríguez, Louise Rollins-Smith, Roberto Ibáñez, Armando A Durant-Archibold, Marcelino Gutiérrez
ETHNOPHARMACOLOGICAL RELEVANCE: Among amphibians, 15 of the 47 species reported to be used in traditional medicines belong to the family Bufonidae, which demonstrates their potential in pharmacological and natural products research. For example, Asian and American tribes use the skin and the parotoid gland secretions of some common toads in the treatment of hemorrhages, bites and stings from venomous animals, skin and stomach disorders, as well as several types of cancers. OVERARCHING OBJECTIVE: In addition to reviewing the occurrence of chemical constituents present in the family Bufonidae, the cytotoxic and biomedical potential of the active compounds produced by different taxa are presented...
December 26, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28028395/microbiological-assessment-of-moringa-oleifera-extracts-and-its-incorporation-in-novel-dental-remedies-against-some-oral-pathogens
#16
Hanaa Elgamily, Amani Moussa, Asmaa Elboraey, Hoda El-Sayed, Marwa Al-Moghazy, Aboelfetoh Abdalla
AIM: To assess the antibacterial and antifungal potentials of different parts of Moringa oleifera plant using different extraction methods in attempts to formulate natural dental remedies from this plant. MATERIAL AND METHODS: Three solvents extracts (Ethanol, acetone, and ethyl acetate) of different parts of Egyptian Moringa tree were prepared and tested against oral pathogens: Staphylococcus aureus, Streptococcus mutans, and Candida albicans using disc diffusion method; As well as to incorporate the plant extract to formulate experimental toothpaste and mouthwash...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28025940/a-mini-review-on-the-chemistry-and-neuroprotective-effects-of-silymarin
#17
Kasi Pandima Devi, Dicson Sheeja Malar, Nady Braidy, Seyed Mohammad Nabavi, Seyed Fazel Nabavi
The plant milk thistle and silymarin has been traditionally used as a natural remedy for the treatment of various ailments including neurological disorders such Alzheimer's and Parkinson's Disease and cerebral ischemia for over 2000 years. The neuroprotective effects conferred by silymarin include modulation of various antioxidant mechanisms, and several kinases involved in cell signaling pathways, inhibition of the inflammatory response generated during neurodegeneration, neurotropic effects, regulation of neurotransmitters and inhibition of apoptosis...
December 27, 2016: Current Drug Targets
https://www.readbyqxmd.com/read/28024809/immobilization-of-metals-in-contaminated-soils-using-natural-polymer-based-stabilizers
#18
Xue Tao, Aimin Li, Hu Yang
Three low-cost natural polymer materials, namely, lignin (Ln), carboxymethyl cellulose, and sodium alginate, were used for soil amendment to immobilize lead and cadmium in two contaminated soil samples collected from a mining area in Nanjing, China. The remediation effects of the aforementioned natural polymers were evaluated by toxicity characteristic leaching procedure (TCLP) and sequential extractions. The stabilizers could lower the bioavailability of Pb and Cd in the contaminated soils, and the amount of the exchangeable forms of the aforementioned two metals were reduced evidently...
December 24, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/28024521/a-novel-interpretation-of-the-fractional-inhibitory-concentration-index-the-case-origanum-vulgare-l-and-leptospermum-scoparium-j-r-et-g-forst-essential-oils-against-staphylococcus-aureus-strains
#19
Filippo Fratini, Simone Mancini, Barbara Turchi, Elisabetta Friscia, Luisa Pistelli, Giulia Giusti, Domenico Cerri
Origanum vulgare (oregano) and Leptospermum scoparium (manuka) were traditionally employed as natural remedies for infected wounds and skin injuries where Staphylococcus aureus is mainly involved. The first aim of this study was to investigate oregano and manuka essential oils (EOs) chemical compositions and evaluate their antibacterial activity (MIC, Minimum Inhibitory Concentration) against fourteen S. aureus wild strains. The second aim was to evaluate the antibacterial activities of oregano and manuka EOs mixed in different combination (FIC, Fractional Inhibitory Concentration) with an improved chequerboard technique...
January 2017: Microbiological Research
https://www.readbyqxmd.com/read/28013464/in-situ-remediation-of-contaminated-marinesediment-an-overview
#20
G Lofrano, G Libralato, D Minetto, S De Gisi, F Todaro, B Conte, D Calabrò, L Quatraro, M Notarnicola
Sediment tends to accumulate inorganic and persistent hydrophobic organic contaminants representing one of the main sinks and sources of pollution. Generally, contaminated sediment poses medium- and long-term risks to humans and ecosystem health; dredging activities or natural resuspension phenomena (i.e., strongly adverse weather conditions) can remobilize pollution releasing it into the water column. Thus, ex situ traditional remediation activities (i.e., dredging) can be hazardous compared to in situ techniques that try to keep to a minimum sediment mobilization, unless dredging is compulsory to reach a desired bathymetric level...
December 24, 2016: Environmental Science and Pollution Research International
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