keyword
MENU ▼
Read by QxMD icon Read
search

Carcinoma gallbladder

keyword
https://www.readbyqxmd.com/read/28314252/clinical-target-volume-in-biliary-carcinoma-a-systematic-review-of-pathological-studies
#1
REVIEW
Ilaria Marinelli, Alessandra Guido, Lorenzo Fuccio, Andrea Farioli, Valeria Panni, Lucia Giaccherini, Alessandra Arcelli, Giorgio Ercolani, Giovanni Brandi, Silvia Cammelli, Andrea Galuppi, Gabriella Macchia, Rezarta Frakulli, Gian C Mattiucci, Francesco Cellini, Milly Buwenge, Matteo Renzulli, Francesco Deodato, Savino Cilla, Vincenzo Valentini, Vincenzo Tombolini, Rita Golfieri, Alessio G Morganti
BACKGROUND/AIM: Radiotherapy is a treatment option for both adjuvant and neo-adjuvant settings for biliary tract cancer. Guidelines on the delineation of the target volume of lymph nodes are lacking; only generic indications are available, without specific recommendations for different primary tumour locations (e.g. intrahepatic, extrahepatic biliary tract or gallbladder cancer). The aim of this study was to systematically review available literature to provide recommendations on lymph node target volume delineation in patients with unresectable biliary tumour...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28262591/robotics-in-hepatobiliary-surgery-initial-experience-first-reported-case-series-from-india
#2
S Goja, M K Singh, A S Soin
INTRODUCTION: Robotic surgical system's ability to perform complex hepatobiliary surgeries is gaining momentum with outcomes similar to open surgery and advantages of minimal access surgery. The authors present their initial experience of a heterogenous spectrum of robotic hepatobiliary cases and the first reported case series from India. METHODS: Retrospective review of hepatobiliary cases done robotically from February 2015 to January 2016 was done. RESULTS: The series has ten patients; with median age of 45 years (range 15-72)...
February 20, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28251014/primary-pure-squamous-cell-carcinoma-of-the-gallbladder-locally-invading-the-liver-duodenum-and-stomach-a-case-report-and-literature-review
#3
Aldrin C Alpuerto, Maximo E Mora, R Jonathan Robitsek, Sebastian D Schubl
Primary pure squamous cell carcinoma (SCC) of the gallbladder is an exceptionally rare type of tumor that comprises only 1% of all gallbladder cancer. SCC of the gallbladder portends a worse prognosis than the more common adenocarcinoma variant because of its aggressive invasion to local structures and because it is often diagnosed at an advanced stage. Owing to its rarity, diagnosis and management can be challenging. Herein, we present the case of a 75-year-old female complaining of abdominal pain, nausea, and vomiting...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28239818/identification-of-mir-146b-5p-in-tissues-as-a-novel-biomarker-for-prognosis-of-gallbladder-carcinoma
#4
Y-P Lv, W Shi, H-X Liu, X-J Kong, D-L Dai
OBJECTIVE: Increasing evidence has suggested that dysregulation of microRNAs (miRNAs) could contribute to tumor progression. The aim of present study was to evaluate the feasibility of using miR-146b-5p as a prognostic biomarker in gallbladder cancer (GBC). PATIENTS AND METHODS: We collected 150 pairs of tissue specimens from patients with GBC and adjacent normal specimens. The expression level of miR-146b-5p was measured in 150 GBC tissues and adjacent normal tissues RT-qPCR...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28230007/laparoscopic-combined-with-percutaneous-ablation-for-hepatocellular-carcinoma-under-liver-capsule-a-single-chinese-center-experience-of-thirty-patients
#5
Zhe Tang, Yi Zhu, Kezhong Tang, Linping Dong, Bin Yang, Heqin Fang, Yulian Wu, Bo Zhang
AIM OF STUDY: For the tumor lesions close to capsule of the liver, traditional percutaneous radiofrequency ablation (PRFA) is limited due to high incidence of postoperative complications. The aim of the present study is to whether laparoscopic combined with PRFA (LCPR) could effectively ablate the tumor lesions close to capsule of the liver. METHODS: A total of 119 patients with subcapsular hepatocellular carcinoma (HCC) were divided into two groups: PRFA group (89 patients) and LCPR group (30 patients)...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28222323/a-case-report-of-the-clear-cell-variant-of-gallbladder-carcinoma
#6
Ravi Maharaj, Christo Cave, Kevin Sarran, Nigel Bascombe, Dilip Dan, Wesley Greaves, Wayne A Warner
INTRODUCTION: Clear cell gallbladder carcinoma accounts for less than 1% of all gallbladder malignancies and demonstrates its unique histopathological characteristics in patients with no prior medical illness or familial predisposition. PRESENTATION OF CASE: Here we present a case of a 56-year-old female, with no prior medical conditions presented with a 2-month history of upper abdominal pain. Routine hematological and biochemical tests were unremarkable. An abdominal ultrasound revealed the presence of a gallbladder calculi, and a fundic mass while magnetic resonance cholangiopancreatography revealed a 8...
January 12, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28216422/systemic-chemotherapy-combined-with-resection-for-locally-advanced-gallbladder-carcinoma-surgical-and-survival-outcomes
#7
John M Creasy, Debra A Goldman, Vikas Dudeja, Maeve A Lowery, Andrea Cercek, Vinod P Balachandran, Peter J Allen, Ronald P DeMatteo, T Peter Kingham, Michael I D'Angelica, William R Jarnagin
BACKGROUND: Preoperative chemotherapy is a strategy for converting to resection and/or assessing disease biology before operation. The utility of such an approach in gallbladder carcinoma (GBCA) is unknown. This study evaluated outcomes of GBCA patients treated with chemotherapy for locally advanced or lymph node-involved tumors. STUDY DESIGN: Patients who received systemic chemotherapy for locally advanced or lymph node-positive GBCA were identified from a departmental database...
February 13, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28216138/clinicopathologic-characteristics-of-young-patients-with-gallbladder-cancer
#8
Sung-Im Do, Hyoun Wook Lee, Jin Hee Sohn, Kyungeun Kim
Gallbladder cancer is the most common biliary tract cancer and the fifth most common cancer of the digestive system. However, the clinicopathologic features of gallbladder cancer in young Korean patients have not been studied. This study included 101 consecutive cases of gallbladder cancer that underwent cholecystectomy at Kangbuk Samsung Hospital from December 1990 to March 2011. The patients were divided into two groups by age at initial diagnosis of gallbladder cancer: a young patient group aged less than 45 years and an old patient group aged 45 or older...
December 29, 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28195258/linitis-plastica-like-primary-signet-ring-cell-carcinoma-of-the-gallbladder-an-extremely-rare-variant
#9
S Agarwal, P Pandey, P Durgapal, M Krishna
Signet ring carcinoma (SRCC) of gallbladder is an extremely rare tumor accounting for approximately 3% of all gallbladder carcinomas, with a handful of case reports in the literature. We report a case of signet ring cell carcinoma of the gallbladder in a 70 year-old female who was operated upon after the preoperative diagnosis of cholecystitis with cholelithiasis, based on ultrasonographic findings and subsequently diagnosed as signet ring cell carcinoma of the gallbladder on histopathological examination. Grossly there was no discrete growth, instead tumor presented as linitis plastica like diffuse thickening of the gallbladder wall...
December 2016: Pathologica
https://www.readbyqxmd.com/read/28195110/a-case-of-gallbladder-mass-malakoplakia-the-tumor-mimicker
#10
Kanwaljeet Singh, Tathagatta Chatterjee
Diagnosis of malakoplakia presenting as gall bladder mass is a diagnostic dilemma faced by pathologists, radiologists, and surgeons. Malakoplakia is a rare inflammatory disorder and tumor mimicker usually occurring in the urinary tract, may occasionally be found in gall bladder. Here, we present a rare case, presenting as gall bladder mass in a known case of gallstone disease, clinically suspected as carcinoma and later turned out to be malakoplakia in gall bladder.
January 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28178656/stathmin-decreases-cholangiocarcinoma-cell-line-sensitivity-to-staurosporine-triggered-apoptosis-via-the-induction-of-erk-and-akt-signaling
#11
Yueqi Wang, Zhihui Gao, Dexiang Zhang, Xiaobo Bo, Yaojie Wang, Jiwen Wang, Sheng Shen, Han Liu, Tao Suo, Hongtao Pan, Zhilong Ai, Houbao Liu
Cholangiocarcinoma is a rare, but highly fatal malignancy. However, the intrinsic mechanism involved in its tumorigenesis remains obscure. An urgent need remains for a promising target for cholangiocarcinoma biological therapies. Based on comparative proteomical technologies, we found 253 and 231 different spots in gallbladder tumor cell lines and cholangiocarcinoma cell lines, respectively, relative to non-malignant cells. Using Mass Spectrometry (MS) and database searching, we chose seven differentially expressed proteins...
February 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28178615/long-non-coding-rna-tug1-promotes-cell-proliferation-and-metastasis-by-negatively-regulating-mir-300-in-gallbladder-carcinoma
#12
Fei Ma, Shou-Hua Wang, Qiang Cai, Long-Yang Jin, Di Zhou, Jun Ding, Zhi-Wei Quan
BACKGROUND: As we all know, long non-coding RNAs (lncRNAs) have been reported to play vital roles in various human cancers. In this study, we aimed to explore the role of lncRNA TUG1 in gallbladder carcinoma (GBC) development. METHODS: Total RNA was extracted from the tissues of thirty GBC patients, four GBC cell lines. We detected the expression levels of TUG1 using quantitative real-time PCR. We performed CCK8, colony formation, transwell invasion and apoptosis assays to study the effects of TUG1 on GBC cell proliferation and invasion...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28163293/a-case-of-poorly-differentiated-mucinous-carcinoma-of-the-gallbladder-that-exhibited-a-peculiar-morphology
#13
Takahiro Urata, Michiko Nagamine, Naotaka Kugiyama, Kana Noda, Ryo Ichikawa, Masataka Takeguchi, Kazuhito Yoshimoto, Nobuhiro Minami, Hideki Kitada, Yoshi Takekuma
A 65-year-old female presented with an elevated lesion that was identified in the gallbladder fundus via abdominal ultrasound during a medical checkup. The tumor was a pedunculated lesion, measuring 30mm in diameter, that exhibited a blood flow pattern with gradual dense staining throughout the equilibrium phase on the abdominal contrast computed tomography and a high signal intensity on T2-weighted magnetic resonance imaging. Histopathological findings revealed the proliferation of poorly differentiated adenocarcinoma, including signet ring cells, throughout the tumor along with the formation of a mucous lake...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28133236/-a-case-of-gallbladder-carcinoma-and-breast-cancer-associated-with-pancreaticobiliary-maljunction
#14
Takeshi Hijikawa, Hiroaki Kitade, Hidesuke Yanagida, Masanori Yamada, Noriko Sueoka, Aiko Ueda, Yu Tsubota, Daigo Yamamoto, Kazuhiko Yoshioka, Masanori Kon
We report a case of gallbladder cancer and right breast cancer associated with pancreaticobiliary maljunction.The patient was a 74-year-old woman who presented with abdominal pain due to cholecystitis.Abdominal CT detected a gallbladder tumor and right breast tumor.Enhanced CT and MRCP examination revealed gallbladder cancer and right breast cancer associated with pancreaticobiliary maljunction.We performed a gallbladder bed resection, bile duct resection, and right total mastectomy.The histopathological diagnosis of the gallbladder was moderately tubular adenocarcinoma and that of the breast tumor was scirrhous carcinoma...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133193/-a-case-of-adenocarcinoma-of-the-vater-papilla-treated-with-pancreatoduodenectomy-after-hepaticojejunostomy-for-prior-adenocarcinoma-of-the-gallbladder
#15
Yu Takeda, Yoshito Tomimaru, Kozo Noguchi, Hirotsugu Nagase, Atsushi Hamabe, Masashi Hirota, Kazuteru Oshima, Tsukasa Tanida, Tomono Kawase, Shunji Morita, Hiroshi Imamura, Takashi Iwazawa, Kenzo Akagi, Shiro Adachi, Keizo Dono
A 77-year-old man was diagnosed with acute cholecystitis and underwent laparoscopic cholecystectomy. Since adenocarcinoma in the gallbladder was detected by histopathological examination, he received additional resection for the carcinoma: partial hepatectomy(S4a, S5), extrahepatic bile duct resection, and hepaticojejunostomy. Five years after the surgery, he was diagnosed with adenocarcinoma of the Vater papilla. Pancreatoduodenectomy was performed. During the surgery, the prior hepaticojejunostomy and jejunojejunostomy were preserved, and the gastrointestinal tract was cut at the stomach and jejunum 5 cm from the Treitz ligament...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28132788/prognostic-heterogeneity-of-the-seventh-edition-of-uicc-stage-iii-gallbladder-carcinoma-which-patients-benefit-from-surgical-resection
#16
J Sakata, T Kobayashi, T Ohashi, Y Hirose, K Takano, K Takizawa, K Miura, H Ishikawa, K Toge, K Yuza, D Soma, T Ando, T Wakai
BACKGROUND: This study sought to evaluate the prognostic heterogeneity of Stage III (Union for International Cancer Control, seventh edition) gallbladder carcinoma. METHODS: Of 175 patients enrolled with gallbladder carcinoma who underwent radical resection, 22 were classified with Stage IIIA disease (T3N0M0) and 46 with Stage IIIB disease (T2N1M0 [n = 23] and T3N1M0 [n = 23]). The median number of retrieved lymph nodes per patient was 18. RESULTS: This staging system failed to stratify outcomes between Stages IIIA and IIIB; survival after resection was better for patients with Stage IIIB disease than for patients with Stage IIIA disease, with 5-year survival of 54...
January 19, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28118609/the-clinical-value-of-lncrna-neat1-in-digestive-system-malignancies-a-comprehensive-investigation-based-on-57-microarray-and-rna-seq-datasets
#17
Dan-Dan Xiong, Zhen-Bo Feng, Wei-Luan Cen, Jing-Jing Zeng, Lu Liang, Rui-Xue Tang, Xiao-Ning Gan, Hai-Wei Liang, Zu-Yun Li, Gang Chen, Dian-Zhong Luo
This comprehensive investigation was performed to evaluate the expression level and potential clinical value of NEAT1 in digestive system malignancies. A total of 57 lncRNA datasets of microarray or RNA-seq and 5 publications were included. The pooled standard mean deviation (SMD) indicated that NEAT1 was down-regulated in esophageal carcinoma (ESCA, SMD = -0.35, 95% CI: -0.5~-0.20, P < 0.0001) and hepatocellular carcinoma (HCC, SMD = -0.47, 95% CI: -0.60~-0.34, P < 0.0001), while in pancreatic cancer (PC), NEAT1 was up-regulated (SMD = 0...
January 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28109315/evaluation-of-surgical-treatment-for-incidental-gallbladder-carcinoma-diagnosed-during-or-after-laparoscopic-cholecystectomy-single-center-results
#18
Masashi Utsumi, Hideki Aoki, Tomoyoshi Kunitomo, Yutaka Mushiake, Isao Yasuhara, Takashi Arata, Koh Katsuda, Kohji Tanakaya, Hitoshi Takeuchi
BACKGROUND: Laparoscopic cholecystectomy (LC) is the accepted standard management for benign gallbladder disease. LC rarely results in a diagnosis of incidental gallbladder carcinoma (IGBC). The aim of our study was to report our experience with IGBC diagnosed during or following LC. METHODS: Between January 2008 and January 2015, 352 patients underwent LC at Iwakuni Clinical Center. Among these patients, 8 (2.3%) were diagnosed with IGBC. We evaluated their characteristics, surgical related variables, histopathological findings and surgical outcomes...
January 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28105553/does-ca-19-9-have-prognostic-relevance-in-gallbladder-carcinoma-gbc
#19
Sushma Agrawal, Able Lawrence, Rajan Saxena
BACKGROUND: There is a scarce data on prognostic relevance of carbohydrate antigen (CA 19-9). This retrospective study was undertaken to evaluate its prognostic relevance in different prognostic subsets of gallbladder carcinoma (GBC). MATERIALS AND METHODS: One hundred forty-one patients of GBC treated between January 2012 and December 2014 were the subjects of this retrospective analysis. Baseline CA 19-9 levels of four cohorts of patients: extended cholecystectomy (EC), simple cholecystectomy (SC) with residual or recurrent disease, locally advanced disease (LAGBC) and metastatic disease were ascertained...
January 20, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28105220/overexpression-of-thy1-and-itga6-is-associated-with-invasion-metastasis-and-poor-prognosis-in-human-gallbladder-carcinoma
#20
Dan-Hua Zhang, Zhu-Lin Yang, En-Xiang Zhou, Xiong-Ying Miao, Qiong Zou, Jing-He Li, Lu-Feng Liang, Gui-Xiang Zeng, Sen-Lin Chen
Gallbladder cancer (GBC) is a rare but highly aggressive cancer for which no well-accepted prognostic biomarkers have been identified. Thymus cell antigen 1 (Thy1), also known as cluster of differentiation (CD)90, and integrin α6 (ITGA6), also known as CD49f, are important molecules in cancer and putative markers of various stem cell types. However, their role in GBC remains to be elucidated. In the present study, Thy1 and ITGA6 expression status in clinical GBC samples, which comprised squamous cell/adenosquamous carcinoma (SC/ASC) and adenocarcinoma (AC) subtypes, was investigated...
December 2016: Oncology Letters
keyword
keyword
19938
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"