keyword
https://read.qxmd.com/read/38655998/comparison-of-rocuronium-priming-vs-standard-rapid-sequence-intubation-technique-in-emergency-department-patients-requiring-intubation
#1
RANDOMIZED CONTROLLED TRIAL
Nurullah İshak Işık, Ayhan Özhasenekler, Çağdaş Yıldırım, Alp Şener, Fatih Ahmet Kahraman, Gül Pamukçu Günaydın
OBJECTIVE: In our study, we aimed to compare the effect of standard rapid sequence intubation protocol and the application of rocuronium priming technique on the procedure time and hemodynamic profile. METHODS: Patients who applied to the emergency department and needed rapid sequence intubation were included in our study, which we conducted with a randomized controlled design. Randomization in the study was made according to the order of arrival of the cases. Rapid sequence intubation was performed in the standard group...
2024: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/38655490/fecal-bacteria-contamination-of-floodwaters-and-a-coastal-waterway-from-tidally-driven-stormwater-network-inundation
#2
JOURNAL ARTICLE
M M Carr, A C Gold, A Harris, K Anarde, M Hino, N Sauers, G Da Silva, C Gamewell, N G Nelson
Inundation of coastal stormwater networks by tides is widespread due to sea-level rise (SLR). The water quality risks posed by tidal water rising up through stormwater infrastructure (pipes and catch basins), out onto roadways, and back out to receiving water bodies is poorly understood but may be substantial given that stormwater networks are a known source of fecal contamination. In this study, we (a) documented temporal variation in concentrations of Enterococcus spp. (ENT), the fecal indicator bacteria standard for marine waters, in a coastal waterway over a 2-month period and more intensively during two perigean spring tide periods, (b) measured ENT concentrations in roadway floodwaters during tidal floods, and (c) explained variation in ENT concentrations as a function of tidal inundation, antecedent rainfall, and stormwater infrastructure using a pipe network inundation model and robust linear mixed effect models...
April 2024: GeoHealth
https://read.qxmd.com/read/38654208/fractional-exhaled-nitric-oxide-in-idiopathic-pulmonary-arterial-hypertension-and-mixed-connective-tissue-disease-complicating-pulmonary-hypertension
#3
JOURNAL ARTICLE
Jianhua Xu, Xingxing Sun, Yuan Cao, Hanqing Zhu, Wenlan Yang, Jinming Liu, Jian Guo
BACKGROUND: Fractional exhaled nitric oxide (FeNO) has been extensively studied in various causes of pulmonary hypertension (PH), but its utility as a noninvasive marker remains highly debated. The objective of our study was to assess FeNO levels in patients with idiopathic pulmonary arterial hypertension (IPAH) and mixed connective tissue disease complicating pulmonary hypertension (MCTD-PH), and to correlate them with respiratory functional data, disease severity, and cardiopulmonary function...
April 23, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38651573/mechanical-ventilation-during-extracorporeal-membrane-oxygenation-support-new-trends-and-continuing-challenges
#4
JOURNAL ARTICLE
Konstanty Szuldrzynski, Mariusz Kowalewski, Justyna Swol
BACKGROUND: The impact of mechanical ventilation on the survival of patients supported with veno-venous extracorporeal membrane oxygenation (V-V ECMO) due to severe acute respiratory distress syndrome (ARDS) remains still a focus of research. METHODS: Recent guidelines, randomized trials, and registry data underscore the importance of lung-protective ventilation during respiratory and cardiac support on ECMO. RESULTS: This approach includes decreasing mechanical power delivery by reducing tidal volume and driving pressure as much as possible, using low or very low respiratory rate, and a personalized approach to positive-end expiratory pressure (PEEP) setting...
April 2024: Perfusion
https://read.qxmd.com/read/38651446/flexible-and-rigid-bronchoscopy-for-critically-ill-children-on-extracorporeal-membrane-oxygenation
#5
JOURNAL ARTICLE
Ashley Young, Krupa Patel, Kiona Allen, Saied Ghadersohi, Matthew Rowland, Inbal Hazkani
BACKGROUND: We aim to describe our experience with bronchoscopy to diagnose and relieve tracheobronchial obstruction in anticipation of decannulation in children on extracorporeal membrane oxygenation (ECMO) support. METHODS: A retrospective cohort study of children on ECMO between 1/2018 and 12/2022. RESULTS: A total of 107 children required ECMO support during the study period for cardiac (n = 48, 45%), pulmonary (n = 38, 36%), or cardiopulmonary dysfunction (n = 21, 20%)...
April 23, 2024: Laryngoscope
https://read.qxmd.com/read/38651343/prehospital-surgical-cricothyrotomy-in-a-ground-based-9-1-1-ems-system-a-retrospective-review
#6
JOURNAL ARTICLE
Al Lulla, Robert Dickson, Michael Wells, Matthew Gilbert, Kelly Rogers Keene, Casey Patrick
BACKGROUND: Airway management is a cornerstone in the prehospital care of critically ill or injured patients. Surgical cricothyrotomy offers a rapid and effective solution when oxygenation and ventilation fail using less-invasive techniques. However, the exact indications, incidence, and success of prehospital surgical cricothyrotomy are unknown, with variable rates reported in the literature. This study aimed to examine prehospital indications and success rates for surgical cricothyrotomy within a large, suburban, ground-based Emergency Medical Services (EMS) system...
April 23, 2024: Prehospital and Disaster Medicine
https://read.qxmd.com/read/38650047/respiratory-drive-a-journey-from-health-to-disease
#7
REVIEW
Dimitrios Georgopoulos, Maria Bolaki, Vaia Stamatopoulou, Evangelia Akoumianaki
Respiratory drive is defined as the intensity of respiratory centers output during the breath and is primarily affected by cortical and chemical feedback mechanisms. During the involuntary act of breathing, chemical feedback, primarily mediated through CO2 , is the main determinant of respiratory drive. Respiratory drive travels through neural pathways to respiratory muscles, which execute the breathing process and generate inspiratory flow (inspiratory flow-generation pathway). In a healthy state, inspiratory flow-generation pathway is intact, and thus respiratory drive is satisfied by the rate of volume increase, expressed by mean inspiratory flow, which in turn determines tidal volume...
April 22, 2024: Journal of Intensive Care
https://read.qxmd.com/read/38649817/diagnostic-utility-of-capnography-in-emergency-department-triage-for-screening-acidemia-a-pilot-study
#8
JOURNAL ARTICLE
Paul Peng, Alex F Manini
BACKGROUND: Capnography is a quantitative and reliable method of determining the ventilatory status of patients. We describe the test characteristics of capnography obtained during Emergency Department triage for screening acidemia. RESULTS: We performed an observational, pilot study of adult patients presenting to Emergency Department (ED) triage. The primary outcome was acidemia, as determined by the basic metabolic panel and/or blood gas during the ED visit. Secondary outcomes include comparison of estimated and measured respiratory rates (RR), relationships between end-tidal CO2 (EtCO2 ) and venous partial pressure of CO2 , admission disposition, in-hospital mortality during admission, and capnogram waveform analysis...
April 22, 2024: International Journal of Emergency Medicine
https://read.qxmd.com/read/38647555/description-of-roseibium-sediminicola-sp-nov-isolated-from-sediment-of-a-tidal-flat-on-the-yellow-sea-coast
#9
JOURNAL ARTICLE
Soyeon Ahn, Veeraya Weerawongwiwat, Yunjeong Lee, David Hyung-Sun Choi, Jong-Hwa Kim, Jung-Hoon Yoon, Jung-Sook Lee, Ampaitip Sukhoom, Wonyong Kim
A Gram-stain-negative, aerobic, rod-shaped, motile, flagellated bacterial strain, designated as CAU 1639T , was isolated from the tidal flat sediment on the Yellow Sea in the Republic of Korea. Growth of the isolate was observed at 20-37 °C, at pH 5.0-10.5 and with 0-7% (w/v) NaCl. The genomic DNA G + C content was 60.8%. Phylogenetic analysis, grounded on 16S rRNA gene sequencing, revealed that strain CAU 1639T was closely related to species within the genus Roseibium. It shared the highest similarity with Roseibium album CECT 5095T , followed by Roseibium aggregatum IAM 12614T and Roseibium salinum Cs25T , with 16S rRNA gene sequence similarity ranging from 98...
April 22, 2024: Current Microbiology
https://read.qxmd.com/read/38646587/lung-protective-ventilation-during-pregnancy-an-observational-cohort-study
#10
JOURNAL ARTICLE
Yasaswi Kislovskiy, Alisse Hauspurg, Chenell Donadee, Sara Sakamoto, Raghavan Murugan
Objectives  We sought to describe characteristics of mechanically ventilated pregnant patients, evaluate utilization of low-tidal-volume ventilation (LTVV) and high-tidal-volume ventilation (HTVV) by trimester, and describe maternal and fetal outcomes by ventilation strategy. Study Design  This is a retrospective cohort study of pregnant women with mechanical ventilation for greater than 24 hours between July 2012 and August 2020 at a tertiary care academic medical center. We defined LTVV as average daily tidal volume 8 mL/kg of less of predicted body weight, and HTVV as greater than 8 mL/kg...
April 2024: American Journal of Perinatology Reports
https://read.qxmd.com/read/38643491/ibrutinib-as-part-of-risk-stratified-treatment-for-post-transplant-lymphoproliferative-disorder-the-phase-2-tidal-trial
#11
JOURNAL ARTICLE
Sridhar Chaganti, Shanna Maycock, Graham McIlroy, Aimee E Jackson, Rebecca Bishop, Sarah Johnson, Edward Kanfer, Shireen Kassam, Kate Cwynarski, David J Wrench, Arvind Arumainathan, Christopher P Fox, Rod J Johnson, Pamela McKay, Shankara Paneesha, Clare Rowntree, Constantine Balotis, Graham P Collins, Andrew J Davies, Josh Wright, Sarah Burns, Arian Dominic John Laurence, Keith Wheatley, Tobias Menne
Post-transplant lymphoproliferative disorder (PTLD) is a rare complication of solid organ transplantation, and cytotoxic chemotherapy is associated with treatment-related morbidity and mortality. Current treatment takes a sequential, risk-stratified approach, patients with low-risk disease following initial immunotherapy can avoid escalation to immunochemotherapy. TIDaL is a prospective, single-arm phase 2 trial investigating the activity and tolerability of ibrutinib combined with risk-stratified therapy for first-line treatment of PTLD...
April 21, 2024: Blood
https://read.qxmd.com/read/38641793/successful-management-of-pulmonary-edema-secondary-to-accidental-electrocution-in-a-young-dog
#12
JOURNAL ARTICLE
Eduardo A Díaz, Carolina Sáenz, Diana Torres, Andrés Silva, Gilberto Segnini
BACKGROUND: Human records describe pulmonary edema as a life-threatening complication of electric shock. Successful management requires prompt recognition and intensive care. However, in companion animals, electrocutions are rarely reported, even though domestic environments are full of electrical devices and there is always the possibility of accidental injury. Therefore, it is important for veterinarians to know more about this condition in order to achieve successful patient outcomes...
April 19, 2024: BMC Veterinary Research
https://read.qxmd.com/read/38641097/nutrient-dynamics-in-wetland-systems-associated-with-hydrological-and-anthropogenic-variations-in-the-south-of-samboromb%C3%A3-n-bay-argentina
#13
JOURNAL ARTICLE
M P Pasquale Pérez, E Carol, L Santucci, Y L Idaszkin
Wetlands provide numerous ecosystem services to the environment, such as nutrient removal and storage. The aim of this work is to evaluate the nutrient dynamics in different sectors within wetland systems in the south of the Samborombón Bay (Argentina) based on hydrological and/or anthropogenic variations. For this purpose, the hydrological features of the wetland were defined through the analysis of satellite images, precipitation and tidal data, and field surveys. Three sectors were identified in the wetland: one with tidal influence, another which is dependent on rainfall, and another that receives inputs from rainfall and from a sewage effluent treatment plant...
April 17, 2024: Science of the Total Environment
https://read.qxmd.com/read/38640766/hydrochemistry-and-trace-metals-in-water-and-sediments-in-forest-coastal-wetlands-influenced-by-tidal-regime-in-the-middle-r%C3%A3-o-de-la-plata-estuary-argentina
#14
JOURNAL ARTICLE
Lucía Santucci, Eleonora Carol, Laura G Borda, M Gabriela García
Coastal wetland ecosystems are of utmost importance in regulating the mobility and distribution of elements in water and sediments, being the flooding by tidal events a recurrent process that strongly controls the hydrodynamics of the system. The aim of this work is to assess the control of the tidal regime and anthropogenic influence on the dynamics of some trace metals in water and sediments in the Punta Lara Natural Reserve situated in the Río de la Plata littoral. For that purpose, relationship between tidal flows, surface water and groundwater was evaluated...
April 18, 2024: Marine Pollution Bulletin
https://read.qxmd.com/read/38640563/new-insights-into-substrates-shaped-nutrients-removal-species-interactions-and-community-assembly-mechanisms-in-tidal-flow-constructed-wetlands-treating-low-carbon-to-nitrogen-rural-wastewater
#15
JOURNAL ARTICLE
Le Zhong, Shan-Shan Yang, Han-Jun Sun, Chen-Hao Cui, Tong Wu, Ji-Wei Pang, Lu-Yan Zhang, Nan-Qi Ren, Jie Ding
A limited understanding of microbial interactions and community assembly mechanisms in constructed wetlands (CWs), particularly with different substrates, has hampered the establishment of ecological connections between micro-level interactions and macro-level wetland performance. In this study, CWs with distinct substrates (zeolite, CW_A; manganese ore, CW_B) were constructed to investigate the nutrient removal efficiency, microbial interactions, metabolic mechanisms, and ecological assembly for treating rural sewage with a low carbon-to-nitrogen ratio...
April 11, 2024: Water Research
https://read.qxmd.com/read/38640306/diagnosis-and-rescue-of-malignant-hyperthermia-induced-by-anesthesia-during-radical-surgery-in-a-cervical-cancer-patient-using-the-national-remote-emergency-system-a-case-report
#16
JOURNAL ARTICLE
Yang Xiao, Rou Yu, Juan Gu
RATIONALE: Malignant hyperthermia (MH) is a rare yet serious medical complication that typically arises following general anesthesia or the administration of specific anesthetics. Due to the infrequency of MH, anesthesiologists often lack sufficient expertise in identifying and managing it, leading to misdiagnosis and inappropriate treatment. There is an urgent need to enhance the diagnosis and management of MH through the utilization of relevant tools. PATIENT CONCERNS: In this case, a 52-year-old woman underwent radical cervical cancer surgery under general anesthesia, with no family or significant medical history...
April 19, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38638588/capnography-waveforms-basic-interpretation-in-neonatal-intensive-care
#17
JOURNAL ARTICLE
Emma E Williams, Theodore Dassios, Christopher Harris, Anne Greenough
End-tidal capnography can provide useful clinical information displayed on the ventilator screen or bedside monitor. It is important that clinicians can assess and utilise this information to assist in identifying underlying complications and pulmonary pathology. Sudden change or loss of the CO2 waveform can act as a safety measure in alerting clinicians of a dislodged or blocked endotracheal tube, considering the concurrent flow and volume waveforms. Visual pattern recognition by the clinicians of commonly seen waveform traces may act as an adjunct to other modes of ventilatory monitoring techniques...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38638563/igneous-processes-in-the-small-bodies-of-the-solar-system-ii-small-satellites-and-dwarf-planets
#18
REVIEW
Giovanni Leone, Hiroyuki Tanaka
Evidence of hot and cold igneous processes has been reported in small satellites and dwarf planets of the Solar System. Olivine and pyroxenes were detected in the spectral bands of both small satellites and dwarf planets. The aqueously altered form of olivine and serpentine has been detected in the spectrums of Ceres and Miranda hinting at possible hydrothermal processes in their interiors. Once more, the ubiquitous distribution of 26 Al in the planetary nebula, then evolving in the protoplanetary disk, contributed to the primordial widespread heating...
May 17, 2024: IScience
https://read.qxmd.com/read/38634676/isotopic-evidence-of-long-lived-volcanism-on-io
#19
JOURNAL ARTICLE
Katherine de Kleer, Ery C Hughes, Francis Nimmo, John Eiler, Amy E Hofmann, Statia Luszcz-Cook, Kathy Mandt
Jupiter's moon Io hosts extensive volcanism, driven by tidal heating. The isotopic composition of Io's inventory of volatile chemical elements, including sulfur and chlorine, reflects its outgassing and mass loss history, and thus records information about its evolution. We used millimeter observations of Io's atmosphere to measure sulfur isotopes in gaseous SO2 and SO, and chlorine isotopes in gaseous NaCl and KCl. We find 34 S/32 S = 0.0595 ± 0.0038 (equivalent to δ34 S = +347 ± 86‰), which is highly enriched compared to average Solar System values and indicates that Io has lost 94 to 99% of its available sulfur...
April 18, 2024: Science
https://read.qxmd.com/read/38634505/respiratory-and-chest-wall-mechanics-in-very-preterm-infants
#20
JOURNAL ARTICLE
Benjamin Stoecklin, Chiara Veneroni, Y Jane Choi, J Jane Pillow, Raffaele L Dellacà
Data on static compliance of the chest wall ( C cw ) in preterm infants are scarce. We characterised the static compliance of the lung ( CL ) and C cw to determine their relative contribution to static compliance of the respiratory system ( C rs ) in very preterm infants at 36 weeks' postmenstrual age (PMA). We also aimed to investigate how these compliances were influenced by the presence of bronchopulmonary dysplasia (BPD) and impacted breathing variables. Airway opening pressure, esophageal pressure, and tidal volume ( V T ) were measured simultaneously during a short apnea evoked by the Hering-Breuer reflex...
April 18, 2024: Journal of Applied Physiology
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