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https://www.readbyqxmd.com/read/27906090/muscle-specific-deletion-of-socs3-increases-the-early-inflammatory-response-but-does-not-affect-regeneration-after-myotoxic-injury
#1
Kristy Swiderski, Savant S Thakur, Timur Naim, Jennifer Trieu, Annabel Chee, David I Stapleton, René Koopman, Gordon S Lynch
BACKGROUND: Muscles of old animals are injured more easily and regenerate poorly, attributed in part to increased levels of circulating pro-inflammatory cytokines. The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling cascade is a key mediator of inflammatory cytokine action, and signaling via this pathway is increased in muscles with aging. As a negative regulator of JAK/STAT signaling, a key mediator of myogenic proliferation and differentiation, altered expression of suppressor of cytokine signaling (SOCS3) is likely to have important consequences for muscle regeneration...
October 24, 2016: Skeletal Muscle
https://www.readbyqxmd.com/read/27904798/functional-outcomes-after-distal-biceps-brachii-repair-a-case-series
#2
Christine L Redmond, Tim Morris, Charissa Otto, Tanisha Zerella, John G Semmler, Taaibos Human, Joideep Phadnis, Gregory I Bain
OBJECTIVES: To investigate outcomes after surgical repair of distal biceps tendon rupture and the influence of arm dominance on isokinetic flexion and supination results. BACKGROUND/PURPOSE: While relatively uncommon, rupture of the distal biceps tendon can result in significant strength deficits, for which surgical repair is recommended. The purpose of this study was to assess patient reported functional outcomes and muscle performance following surgery. METHODS: A sample of 23 participants (22 males, 1 female), who had previously undergone surgical repair of the distal biceps tendon, were re-examined at a minimum of one year after surgery...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27904236/influence-of-exercise-on-patients-with-guillain-barr%C3%A3-syndrome-a-systematic-review
#3
Nicholas Simatos Arsenault, Pierre-Olivier Vincent, Bai He Shen Yu, Robin Bastien, Aaron Sweeney
Purpose: To evaluate the effects of exercise interventions on improving physical outcomes in patients with Guillain-Barré syndrome (GBS). Methods: The PubMed database was searched for articles published up to and including February 2015. Randomized controlled trials (RCTs), case reports, and quasi-experimental and single-subject designs published in English-language, peer-reviewed journals that assessed the impact of physical exercise on patients with GBS were included; study quality was assessed using Sackett's rules of evidence...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27900297/effects-of-lymphatic-drainage-and-local-cryo-exposition-regeneration-after-high-intensive-exercises
#4
Michael Behringer, Diana Jedlicka, Molly McCourt, Matthias Ring, Joachim Mester
BACKGROUND: Recovery from exercise and competition is important in sports medicine, particularly when rest periods are short. The objective is to determine the efficacy of cryo exposition (CRY) and manual lymphatic drainage (MLD) to hasten short term recovery of muscle performance after eccentric contractions. METHODS: In a randomized controlled trial, 30 healthy sport students (21 males, 9 females; age: 25.7±2.8 years) performed 4×20 eccentric contractions of knee extensors, followed by 30 min MLD, CRY, or rest (RST) under controlled laboratory environment...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27900149/video-analysis-of-concussion-injury-mechanism-in-under-18-rugby
#5
Sharief Hendricks, Sam O'Connor, Michael Lambert, James C Brown, Nicholas Burger, Sarah Mc Fie, Clint Readhead, Wayne Viljoen
BACKGROUND: Understanding the mechanism of injury is necessary for the development of effective injury prevention strategies. Video analysis of injuries provides valuable information on the playing situation and athlete-movement patterns, which can be used to formulate these strategies. Therefore, we conducted a video analysis of the mechanism of concussion injury in junior-level rugby union and compared it with a representative and matched non-injury sample. METHODS: Injury reports for 18 concussion events were collected from the 2011 to 2013 under-18 Craven Week tournaments...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27898382/towards-real-time-estimation-of-muscle-fiber-conduction-velocity-using-delay-locked-loop
#6
Lin Xu, Chiara Rabotti, Massimo Mischi
Decrease in muscle-fiber conduction velocity (MFCV) during sustained contraction has been widely accepted as myoelectric manifestation of muscle fatigue. Several methods have been proposed in the literature for MFCV estimation by analysing surface electromyography (EMG), e.g., cross-correlation (CC) function and maximum likelihood (ML). However, for all the available methods, windowing of the EMG signal and computationally demanding calculations are required, limiting the possibility to continuously monitor muscle fatigue in real time...
November 24, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/27896952/muscle-strength-in-breast-cancer-patients-receiving-different-treatment-regimes
#7
Oliver Klassen, Martina E Schmidt, Cornelia M Ulrich, Andreas Schneeweiss, Karin Potthoff, Karen Steindorf, Joachim Wiskemann
BACKGROUND: Muscle dysfunction and sarcopenia have been associated with poor performance status, an increased mortality risk, and greater side effects in oncologic patients. However, little is known about how performance is affected by cancer therapy. We investigated muscle strength in breast cancer patients in different adjuvant treatment settings and also compared it with data from healthy individuals. METHODS: Breast cancer patients (N = 255) from two randomized controlled exercise trials, staged 0-III and aged 54...
November 28, 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27895694/edentulous-child-with-allgrove-syndrome-a-rare-case-report
#8
Mohammad Vahedi, Shima Fathi, Hanif Allahbakhshi
Triple-A syndrome, also known as Allgrove syndrome, is a rare autosomal recessive disorder. The 3 features of this syndrome are achalasia, adrenal insufficiency, and alacrima. Achalasia could be the first manifestation of the triple-A syndrome; however, its etiology is unclear. Alacrima is generally asymptomatic but can be detected by obtaining patient history. Although adrenal insufficiency could have manifestations such as asthenia, it might be wrongly diagnosed as muscle fatigue. Vitamin D and calcium supplements are usually prescribed for the prevention of osteoporosis...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27895569/influence-of-lumbar-muscle-fatigue-on-trunk-adaptations-during-sudden-external-perturbations
#9
Jacques Abboud, François Nougarou, Arnaud Lardon, Claude Dugas, Martin Descarreaux
Introduction: When the spine is subjected to perturbations, neuromuscular responses such as reflex muscle contractions contribute to the overall balance control and spinal stabilization mechanisms. These responses are influenced by muscle fatigue, which has been shown to trigger changes in muscle recruitment patterns. Neuromuscular adaptations, e.g., attenuation of reflex activation and/or postural oscillations following repeated unexpected external perturbations, have also been described. However, the characterization of these adaptations still remains unclear...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27895542/effect-of-tart-cherry-juice-on-recovery-and-next-day-performance-in-well-trained-water-polo-players
#10
Rachel McCormick, Peter Peeling, Martyn Binnie, Brian Dawson, Marc Sim
BACKGROUND: Tart Montmorency cherries contain high concentrations of phytochemicals and anthocyanins, which have recently been linked to improved athletic recovery and subsequent performance. To date however, previous work reporting promising results has focused on land-based endurance sports, with any potential benefits to team sports remaining unknown. As such, this investigation set-out to examine the effect of supplemental tart cherry juice (CJ) on recovery and next day athletic performance in highly-trained water-based team sport athletes over seven days...
2016: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/27894796/cognitive-challenges-aging-and-neuromuscular-fatigue
#11
Ashley E Shortz, Ranjana K Mehta
Cognitive challenges, such as concurrent cognitive demands or prior cognitive fatigue, have shown to adversely impact neuromuscular fatigue, specifically in younger adults. Whether these relationships are similar for the aging population remains unclear. The aim of the study was to investigate the effects of different cognitive challenges on handgrip fatigue with aging. Ten younger (24.10 (1.79) years) and ten older (75.90 (7.80) years) females attended three experimental conditions (control, i.e., exercise only, cognitive fatigue prior to exercise, and concurrent mental arithmetic during exercise) on different days...
November 25, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/27893858/reversing-age-related-changes-of-the-laryngeal-muscles-by-chronic-electrostimulation-of-the-recurrent-laryngeal-nerve
#12
Michael Karbiener, Jonathan C Jarvis, Justin D Perkins, Hermann Lanmüller, Martin Schmoll, Hanna S Rode, Claus Gerstenberger, Markus Gugatschka
Age related atrophy of the laryngeal muscles -mainly the thyroarytenoid muscle (TAM)- leads to a glottal gap and consequently to a hoarse and dysphonic voice that significantly affects quality of life. The aim of our study was to reverse this atrophy by inducing muscular hypertrophy by unilateral functional electrical stimulation (FES) of the recurrent laryngeal nerve (RLN) in a large animal model using aged sheep (n = 5). Suitable stimulation parameters were determined by fatiguing experiments of the thyroarytenoid muscle in an acute trial...
2016: PloS One
https://www.readbyqxmd.com/read/27893484/effects-of-pelvic-and-core-strength-training-on-high-school-cross-country-race-times
#13
Anne W Clark, Maggie K Goedeke, Rina Namvong, Derek E Rockwell, Bryan Jason Lehecka, Robert C Manske, Barbara S Smith
Effects of pelvic and core strength training on high school cross-country race times: A randomized control trial.There is only limited research examining the effect of pelvic and core strength training on running performance. Pelvic and core muscle fatigue is believed to contribute to excess motion along frontal and transverse planes which decreases efficiency in normal sagittal plane running motions. The purpose of this study was to determine if adding a six week pelvic and core strengthening program resulted in decreased race times in high school cross-country runners...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27891518/size-and-proportions-of-slow-twitch-and-fast-twitch-muscle-fibers-in-human-costal-diaphragm
#14
Marija Meznaric, Erika Cvetko
Smaller diaphragmatic motor unit potentials (MUPs) compared to MUPs of limb muscles lead to the hypothesis that diaphragmatic muscle fibers, being the generators of MUPs, might be also smaller. We compared autopsy samples of costal diaphragm and vastus lateralis of healthy men with respect to fibers' size and expression of slow myosin heavy chain isoform (MyHC-1) and fast 2A isoform (MyHC-2A). Diaphragmatic fibers were smaller than fibers in vastus lateralis with regard to the mean minimal fiber diameter of slow-twitch (46...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27890479/heart-rate-variability-and-psychometric-responses-to-overload-and-tapering-in-collegiate-sprint-swimmers
#15
Andrew A Flatt, Bjoern Hornikel, Michael R Esco
OBJECTIVES: The purpose of this study was to evaluate cardiac-parasympathetic and psychometric responses to competition preparation in collegiate sprint-swimmers. Additionally, we aimed to determine the relationship between average vagal activity and its daily fluctuation during each training phase. DESIGN: Observational. METHODS: Ten Division-1 collegiate sprint-swimmers performed heart rate variability recordings (i.e., log transformed root mean square of successive RR intervals, lnRMSSD) and completed a brief wellness questionnaire with a smartphone application daily after waking...
November 17, 2016: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/27884793/sex-stress-and-sleep-apnoea-decreased-susceptibility-to-upper-airway-muscle-dysfunction-following-intermittent-hypoxia-in-females
#16
REVIEW
Ken D O'Halloran, Philip Lewis, Fiona McDonald
Obstructive sleep apnoea syndrome (OSAS) is a devastating respiratory control disorder more common in men than women. The reasons for the sex difference in prevalence are multifactorial, but are partly attributable to protective effects of oestrogen. Indeed, OSAS prevalence increases in post-menopausal women. OSAS is characterized by repeated occlusions of the pharyngeal airway during sleep. Dysfunction of the upper airway muscles controlling airway calibre and collapsibility is implicated in the pathophysiology of OSAS, and sex differences in the neuro-mechanical control of upper airway patency are described...
November 21, 2016: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/27882640/physiological-markers-of-exercise-capacity-and-lung-disease-severity-in-cystic-fibrosis
#17
Laurie Smith, Charles C Reilly, Victoria MacBean, Caroline J Jolley, Caroline Elston, John Moxham, Gerrard F Rafferty
BACKGROUND AND OBJECTIVE: Peak aerobic capacity (VO2 peak) is an important outcome measure in cystic fibrosis (CF), but measurement is not widely available and can be influenced by patient motivation, pain and fatigue. Alternative markers of disease severity would be helpful. Neural respiratory drive, measured using parasternal intercostal muscle electromyography (EMGpara), reflects the load to capacity balance of the respiratory system and provides a composite measure of pulmonary function impairment in CF...
November 24, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27882212/resveratrol-and-exercise
#18
Saltuk Bugra Baltaci, Rasim Mogulkoc, Abdulkerim Kasim Baltaci
Although it is recommended for a healthy lifestyle, moderate exercise is known to lead to oxidative stress, inflammation and muscle injury. Hence there are efforts to develop dietary strategies to counter the oxidative stress caused by physical activity. Recently, there has been an interest in the capability of resveratrol (RES) to modulate physical performance and prevent oxidative stress. Despite the inconsistency among reports regarding the topic, it has been suggested that RES delays fatigue by hindering lipid peroxidation...
November 2016: Biomedical Reports
https://www.readbyqxmd.com/read/27874495/evolution-of-multiple-sclerosis-spasticity-associated-symptoms-latest-data
#19
Peter Flachenecker
In addition to muscle stiffness and increasing mobility restrictions, symptoms commonly associated with multiple sclerosis (MS) spasticity are spasms, sleep disturbances, pain, fatigue and bladder dysfunction. Treatment options include trigger factor avoidance, physiotherapy and antispasticity medication. Oral antispasticity agents commonly used in Germany are baclofen, tizanidine and gabapentin, but physician and patient satisfaction with their effectiveness is low. Over the past few years, randomized controlled trials, observational studies and registry data have demonstrated the positive risk:benefit profile of add-on 9-delta-tetra-hydrocannabinol:cannabidiol oromucosal spray for moderate-to-severe resistant MS spasticity...
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874264/photobiomodulation-in-human-muscle-tissue-an-advantage-in-sports-performance
#20
Cleber Ferraresi, Ying-Ying Huang, Michael R Hamblin
Photobiomodulation (PBM) describes the use of red or near-infrared (NIR) light to stimulate, heal, and regenerate damaged tissue. Both preconditioning (light delivered to muscles before exercise) and PBM applied after exercise can increase sports performance in athletes. This review covers the effects of PBM on human muscle tissue in clinical trials in volunteers related to sports performance and in athletes. The parameters used were categorized into those with positive effects or no effects on muscle performance and recovery...
November 22, 2016: Journal of Biophotonics
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