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Muscle fatigue

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https://www.readbyqxmd.com/read/29334581/gender-and-muscle-specific-responses-during-fatiguing-exercise
#1
Ethan C Hill, Terry J Housh, Cory M Smith, Richard J Schmidt, Glen O Johnson
The purpose of the present investigation was to examine potential gender-related differences in electromyographic (EMG) and mechanomyographic (MMG) responses during submaximal, concentric, isokinetic, forearm flexion muscle contractions. Twelve men and twelve women performed concentric peak torque trials prior to (pretest) and following (posttest) a fatiguing exercise bout that consisted of 50 submaximal (65% of concentric peak torque), concentric, isokinetic (60°·s), forearm flexion muscle contractions. Surface EMG and MMG signals were simultaneously recorded from the biceps brachii and brachioradialis muscles...
January 12, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29334129/a-mitochondrial-targeted-antioxidant-improves-myofilament-ca2-sensitivity-during-prolonged-low-frequency-force-depression-at-low-po2
#2
Paulo G Gandra, Amy A Shiah, Leonardo Nogueira, Michael C Hogan
Skeletal muscle can develop a prolonged low frequency-stimulation force depression (PLFFD) following fatigue-inducing contractions. Increased levels of reactive oxygen species (ROS) have been implicated in the development of PLFFD. During exercise the skeletal muscle intracellular PO2 decreases to relatively low levels, and can be further decreased when there is an impairment in O2 diffusion or availability, such as in certain chronic diseases and during exercise at high altitude. Since ROS generation by mitochondria is elevated at very low PO2 in cells, we tested the hypothesis that treatment of muscle fibres with a mitochondrial-targeted antioxidant at a very low, near hypoxic PO2 , can attenuate PLFFD...
January 15, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29333223/development-of-practical-functional-electrical-stimulation-cycling-systems-based-on-an-electromyography-study-of-the-cybathlon-2016
#3
Jetsada Arnin, Traisak Yamsa-Ard, Preechapawan Triponyuwasin, Yodchanan Wongsawat
The purpose of this study was to develop a functional electrical stimulation (FES) system based on the motor driving concept for use by spinal cord injury patients participating in the FES Cycling competition at the Cybathlon 2016. The proposed FES system consists of a low-power control system, a precise processor unit, and a 4-channel stimulation unit. Self-adhesive carbon conductive electrodes were utilized for stimulation. A 26-year-old SCI patient was qualified to participate in the competition. The pilot patient underwent training for 16 months, which included experience with FES stimulation, performing FES cycling, and reducing spasticity, to practice using the FES system...
December 5, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29332743/myoeletric-indices-of-fatigue-adopting-different-rest-intervals-during-leg-press-sets
#4
Humberto Miranda, Marianna Maia, Carlos G de Oliveira, Déborah Farias, Jurandir B da Silva, Vicente P Lima, Jeffrey M Willardson, Gabriel A Paz
INTRODUCTION: The purpose of this study was to examine the acute effect of different rest intervals between multiple sets of the 45° angled leg press exercise (LP45) on surface electromyographic (SEMG) spectral and amplitude indices of fatigue. METHODS: Fifteen recreationally trained females performed three protocols in a randomized crossover design; each consisting of four sets of 10 repetitions with 1 (P1), 3 (P3), or 5 (P5) minute rest intervals between sets...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332237/acute-acetaminophen-ingestion-improves-performance-and-muscle-activation-during-maximal-intermittent-knee-extensor-exercise
#5
Paul T Morgan, Joanna L Bowtell, Anni Vanhatalo, Andrew M Jones, Stephen J Bailey
AIM: Acetaminophen is a commonly used medicine for pain relief and emerging evidence suggests that it may improve endurance exercise performance. This study investigated some of the physiological mechanisms by which acute acetaminophen ingestion might blunt muscle fatigue development. METHODS: Thirteen active males completed 60 × 3 s maximum voluntary contractions (MVC) of the knee extensors with each contraction separated by a 2 s passive recovery period...
January 13, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29332059/analysis-of-skeletal-muscle-performance-using-piezoelectric-film-sensors
#6
Anat Ratnovsky, Emanuel Kusayev, Sara Naftali
A flexible piezoelectric thin film sensor has been proposed recently in several studies for detection of muscle movements. The objective of this study was to investigate the ability of this sensor to assess skeletal muscle performance and fatigue under isokinetic contractions. Simultaneous noninvasive measurements of muscles activity were done using surface electromyography (EMG) electrodes and two thin film piezoelectric sensors. Measurements were taken from the biceps during slow and fast elbow flexion with and without strong grip, during different weight lifting and from the gastrocnemius during treadmill marching at speeds of 4 and of 10 kph...
January 5, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29327673/evaluation-of-the-electromyographic-fatigue-of-the-masseter-and-temporalis-muscles-in-individuals-with-osteoporosis
#7
Veridiana Wanshi Arnoni, Paulo Batista de Vasconcelos, Luiz Gustavo de Sousa, Bruno Ferreira, Marcelo Palinkas, Mariah Acioli Righetti, Gabriel Pádua da Silva, Solange Aparecida Caldeira Monteiro, Simone Cecilio Hallak Regalo, Selma Siéssere
Objectives The objective of this study was to evaluate the electromyographic fatigue of the masseter and temporalis muscles in individuals with and without osteoporosis. Methods Median frequency of the initial, mid, and final periods of the electromyographic signal in the 33 subjects with osteoporosis (OG) and 33 subjects without osteoporosis [control (CG)] was analyzed. Results OG showed a decrease in median frequency along the electromyographic signal, with a significant difference for the right masseter: initial vs...
January 12, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29326166/a-skeletal-muscle-l-type-ca2-channel-with-a-mutation-in-the-selectivity-filter-cav1-1-e1014k-conducts-k
#8
Donald Beqollari, Karen Dockstader, Roger A Bannister
A glutamate to lysine substitution at position 1014 within the selectivity filter of the skeletal muscle L-type Ca2+ channel (CaV1.1) abolishes Ca2+ flux through the channel pore. Mice engineered to exclusively express the mutant channel display accelerated muscle fatigue, changes in muscle composition and altered metabolism relative to wild-type littermates. By contrast, mice expressing another mutant CaV1.1 channel that is impermeable to Ca2+ (CaV1.1 N617D) have shown no detectable phenotypic differences from wild-type mice to date...
January 11, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29324727/frequent-exertion-and-frequent-standing-at-work-by-industry-and-occupation-group-united-states-2015
#9
Taylor M Shockey, Sara E Luckhaupt, Matthew R Groenewold, Ming-Lun Lu
Repeated exposure to occupational ergonomic hazards, such as frequent exertion (repetitive bending or twisting) and frequent standing, can lead to injuries, most commonly musculoskeletal disorders (1). Work-related musculoskeletal disorders have been estimated to cost the United States approximately $2.6 billion in annual direct and indirect costs (2). A recent literature review provided evidence that prolonged standing at work also leads to adverse health outcomes, such as back pain, physical fatigue, and muscle pain (3)...
January 12, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29322520/muscle-cooling-too-much-of-a-good-thing
#10
C Mawhinney, R Allan
It is well documented that strenuous exercise elicits stress on the body, which may lead to physiological impairments and associated reductions in muscle function and fatigue, in the hours and days post-exercise. This article is protected by copyright. All rights reserved.
January 11, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29322223/is-the-timed-loaded-standing-test-a-valid-measure-of-back-muscle-endurance-in-people-with-vertebral-osteoporosis
#11
M Newman, R Newman, T Hughes, K Vadher, K L Barker
Timed loaded standing (TLS) is a suggested measure of back muscle endurance for people with vertebral osteoporosis. Surface electromyography revealed back muscles work harder and fatigue during TLS. The test end-point and total time were associated with back fatigue. The findings help demonstrate the concurrent validity of the TLS test. INTRODUCTION: The TLS test is suggested as a measure of back muscle endurance for patients with vertebral osteoporosis. However, to date, no study has demonstrated that TLS does measure back extensor or erector spinae (ES) muscle endurance...
January 10, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29319776/hypercalcemia-and-acute-renal-insufficiency-following-use-of-a-veterinary-supplement
#12
Marcelo Fernando Ronsoni, Heloisa de Cassia Dos Santos, Bruno da Silveira Colombo, Carina Gabriela Correa, Ana Paula Gomes Moritz, Marisa Helena Cesar Coral, Simone Van de Sande-Lee, Alexandre Hohl
A previously healthy 24 yo male presented with a two-month history of epigastric pain, nausea, vomiting, fatigue and malaise. He reported abuse of different substances, including an injectable veterinary vitamin compound, which contains high doses of vitamin A, D and E, and an oily vehicle that induces local edema and enhances muscle volume. Serum creatinine was 3.1 mg/dL, alanine transaminase 160 mg/dL, aspartate transaminase 11 mg/dL, total testosterone 23 ng/dL, 25-OH-vitamin D >150 ng/mL (toxicity >100), 1,25-OH-vitamin D 80 pg/mL, vitamin A 0...
October 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29318742/extracellular-water-excess-and-increased-self-reported-fatigue-in-chronic-hemodialysis-patients
#13
Kamonwan Tangvoraphonkchai, Andrew Davenport
Hemodialysis patients (HD) commonly report fatigue. Muscle wasting (sarcopenia) and extracellular water (ECW) excess have been reported to be associated with fatigue in other conditions. We wished to determine whether muscle loss and ECW excess were associated with fatigue in HD patients. Patients completed the Multidimensional Fatigue Inventory (MFI), Beck Depression Inventory-II (BDI-II), Patient Health Questionnaires (PHQ-9) and recorded their post-dialysis recovery time. Sessional dialysis data were recorded along with pre- and post-dialysis multi-frequency bioimpedance assessments (MFBIA)...
January 10, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29318030/environmental-temperature-and-exercise-modality-independently-impact-central-and-muscle-fatigue-among-people-with-multiple-sclerosis
#14
Geetika Grover, Michelle Ploughman, Devin T Philpott, Liam P Kelly, Augustine J Devasahayam, Katie Wadden, Kevin E Power, Duane C Button
Background: Heat sensitivity and fatigue limit the ability of multiple sclerosis patients to participate in exercise. Objective: The purpose of this study was to determine the optimal aerobic exercise parameters (environmental temperature and exercise modality) to limit exercise-induced central and muscle fatigue among people with multiple sclerosis. Methods: Fourteen people with multiple sclerosis with varying levels of disability completed four randomized exercise sessions at 65% of the maximal volume of oxygen: body-weight supported treadmill cool (16°C), body-weight supported treadmill room (21°C), total-body recumbent stepper cool and total-body recumbent stepper room...
October 2017: Multiple Sclerosis Journal—Experimental, Translational and Clinical
https://www.readbyqxmd.com/read/29317395/the-role-of-elotuzumab-in-the-treatment-of-relapsed-or-refractory-multiple-myeloma
#15
REVIEW
Jill M Comeau, Katherine Kelly, Gary W Jean
PURPOSE: The pharmacology, pharmacokinetics, clinical efficacy and safety, cost, and place in therapy of elotuzumab for treatment of relapsed or refractory multiple myeloma (MM) are reviewed. SUMMARY: Elotuzumab is a humanized monoclonal antibody that targets the signaling lymphocytic activation molecule (SLAM) protein SLAMF7 and facilitates an antibody-dependent cellular cytotoxicity interaction between myeloma cells and natural killer cells. Elotuzumab has U.S...
January 15, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29316902/the-effect-of-ankle-tape-on-joint-position-sense-after-local-muscle-fatigue-a-randomized-controlled-trial
#16
Akram Jahjah, Dietmar Seidenspinner, Karl Schüttler, Antonio Klasan, Thomas J Heyse, Dominik Malcherczyk, Bilal Farouk El-Zayat
BACKGROUND: Ankle tape is widely used by athletes to prevent ankle sprain. Although there is growing evidence that ankle tape improve joint position sense, but yet it is not clear even if tape improve joint position sense after muscle fatigue, because fatigue impair joint position sense and raise the risk of ankle sprain. The aim of this study is to examine the effect of ankle tape on joint position sense after local muscle fatigue. METHOD: This trial is a randomized controlled trial...
January 9, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29316265/effects-of-chronic-hypoxia-on-diaphragm-function-in-deer-mice-native-to-high-altitude
#17
Neal J Dawson, Sulayman A Lyons, Danielle A Henry, Graham R Scott
AIM: We examined the effects of chronic hypoxia on diaphragm function in high- and low-altitude populations of Peromyscus mice. METHODS: Deer mice (P. maniculatus) native to high altitude and congeneric mice native to low altitude (P. leucopus) were born and raised in captivity to adulthood, and were acclimated to normoxia or hypobaric hypoxia (12 or 9 kPa, simulating hypoxia at 4300 m and 7000 m) for 6-8 weeks. We then measured indices of mitochondrial respiration capacity, force production, and fatigue resistance in the diaphragm...
January 9, 2018: Acta Physiologica
https://www.readbyqxmd.com/read/29313445/body-composition-metabolism-sleep-psychological-and-eating-patterns-of-overtraining-syndrome-results-of-the-eros-study-eros-profile
#18
Flavio A Cadegiani, Claudio E Kater
Overtraining syndrome (OTS) is caused by an imbalance between training, nutrition and resting, and leads to decreased performance and fatigue; however, the precise underlying triggers of OTS remain unclear. This study investigated the body composition, metabolism, eating, sleeping patterns and mood states among participants with OTS. Selected participants were divided into OTS-affected athletes (OTS, n = 14), healthy athletes (ATL, n = 25), and healthy non-physically active controls (NCS, n = 12). Compared to ATL, OTS showed decreased sleep quality (p = 0...
January 9, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29311764/effects-of-beetroot-juice-supplementation-on-intermittent-high-intensity-exercise-efforts
#19
REVIEW
Raúl Domínguez, José Luis Maté-Muñoz, Eduardo Cuenca, Pablo García-Fernández, Fernando Mata-Ordoñez, María Carmen Lozano-Estevan, Pablo Veiga-Herreros, Sandro Fernandes da Silva, Manuel Vicente Garnacho-Castaño
Beetroot juice contains high levels of inorganic nitrate (NO3-) and its intake has proved effective at increasing blood nitric oxide (NO) concentrations. Given the effects of NO in promoting vasodilation and blood flow with beneficial impacts on muscle contraction, several studies have detected an ergogenic effect of beetroot juice supplementation on exercise efforts with high oxidative energy metabolism demands. However, only a scarce yet growing number of investigations have sought to assess the effects of this supplement on performance at high-intensity exercise...
2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29309405/cardinal-features-of-involuntary-force-variability-can-arise-from-the-closed-loop-control-of-viscoelastic-afferented-muscles
#20
Akira Nagamori, Christopher M Laine, Francisco J Valero-Cuevas
Involuntary force variability below 15 Hz arises from, and is influenced by, many factors including descending neural drive, proprioceptive feedback, and mechanical properties of muscles and tendons. However, their potential interactions that give rise to the well-structured spectrum of involuntary force variability are not well understood due to a lack of experimental techniques. Here, we investigated the generation, modulation, and interactions among different sources of force variability using a physiologically-grounded closed-loop simulation of an afferented muscle model...
January 8, 2018: PLoS Computational Biology
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