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https://www.readbyqxmd.com/read/29166757/hybrid-imaging-of-musculoskeletal-infections
#1
Andor W Glaudemans, Napoleone Prandini, Marco DI Girolamo, Giuseppe Argento, Chiara Lauri, Elena Lazzeri, Mario Muto, Luca M Sconfienza, Alberto Signore
This review article highlights the role of radiological and nuclear medicine techniques in diagnosis of musculoskeletal infections with particular regard to hybrid imaging of osteomyelitis, prosthetic joint infections, sternal infections and spine infections. Authors conclude on the complementary role of the several techniques with indications for an appropriate diagnostic flow chart, in the light of the recent EANM guidelines on infection.
November 22, 2017: Quarterly Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29166649/extended-light-exposure-increases-stem-digestibility-and-biomass-production-of-switchgrass
#2
Chunqiao Zhao, Xifeng Fan, Xincun Hou, Yi Zhu, Yuesen Yue, Juying Wu
Switchgrass is a photoperiod-sensitive energy grass suitable for growing in the marginal lands of China. We explored the effects of extended photoperiods of low-irradiance light (7 μmol·m-2·s-1, no effective photosynthesis) on the growth, the biomass dry weight, the biomass allocation, and, especially, the stem digestibility and cell wall characteristics of switchgrass. Two extended photoperiods (i.e., 18 and 24 h) were applied over Alamo. Extended light exposure (18 and 24 h) resulted in delayed heading and higher dry weights of vegetative organs (by 32...
2017: PloS One
https://www.readbyqxmd.com/read/29166586/the-broad-spectrum-of-human-natural-killer-cell-diversity
#3
REVIEW
Aharon G Freud, Bethany L Mundy-Bosse, Jianhua Yu, Michael A Caligiuri
Natural killer (NK) cells provide protection against infectious pathogens and cancer. For decades it has been appreciated that two major NK cell subsets (CD56(bright) and CD56(dim)) exist in humans and have distinct anatomical localization patterns, phenotypes, and functions in immunity. In light of this traditional NK cell dichotomy, it is now clear that the spectrum of human NK cell diversity is much broader than originally appreciated as a result of variegated surface receptor, intracellular signaling molecule, and transcription factor expression; tissue-specific imprinting; and foreign antigen exposure...
November 21, 2017: Immunity
https://www.readbyqxmd.com/read/29166564/optical-control-of-dopamine-receptors-using-a-photoswitchable-tethered-inverse-agonist
#4
Prashant Donthamsetti, Nils Winter, Matthias Schönberger, Joshua Levitz, Cherise Stanley, Jonathan A Javitch, Ehud Y Isacoff, Dirk Trauner
Family A G protein-coupled receptors (GPCRs) control diverse biological processes and are of great clinical relevance. Their archetype rhodopsin becomes naturally light sensitive by binding covalently to the photoswitchable tethered ligand (PTL) retinal. Other GPCRs, however, neither bind covalently to ligands nor are light sensitive. We sought to impart the logic of rhodopsin to light-insensitive Family A GPCRs in order to enable their remote control in a receptor-specific, cell-type-specific and spatio-temporally precise manner...
November 22, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29166521/case-for-diagnosis-systemic-light-chain-amyloidosis-with-cutaneous-involvement
#5
João Renato Vianna Gontijo, Jackson Machado Pinto, Maysa Carla de Paula
Systemic light chain amiloydosis is a rare disease. Due to its typical cutaneous lesions, dermatologists play an essential role in its diagnosis. Clinical manifestations vary according to the affected organ and are often unspecific. Definitive diagnosis is achieved through biopsy. We report a patient with palpebral amyloidosis, typical bilateral ecchymoses and cardiac involvement, without plasma cell dyscrasia or lymphomas. The patient died shortly after the diagnosis.
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166512/segmental-lichen-aureus-an-uncommon-presentation
#6
Pedro de Freitas Silva Torraca, Nathalia Dias Negrão Murback, Nayara de Castro Wiziack, Tânia Christina Marchesi de Freitas, Greicy Mara França
Pigmented purpuric dermatoses are chronic vascular inflammatory conditions characterized by the presence of pigmented macules. Among its different presentations, lichen aureus is distinguished by the lichenoid conformation of its plaques and the predilection for lower limb involvement. Its segmented form is rare and difficult to control, especially in cases of symptomatic lesions. We report a rare case of segmental lichen aureus with six years of evolution associated with light itching. We also discuss the main therapeutic approaches to control the disease...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166495/photodynamic-action-of-the-red-laser-on-propionibacterium-acnes
#7
Rogério Rodrigo Ramos, Jeferson Leandro de Paiva, José Paulo Franco Dos Santos Gomes, Nagib Pezati Boer, José Maria Pereira de Godoy, Fernando Batigalia
BACKGROUND: Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. OBJECTIVE: To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. METHOD: The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light)...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166420/a-comparison-of-marginal-gaps-of-all-ceramic-crowns-constructed-from-scanned-impressions-and-models
#8
Raena Tabesh, James Dudley
PURPOSE: This study compared the marginal gaps of computer-aided design/computer-aided manufacture (CAD/CAM)-fabricated all-ceramic crowns constructed from scanned impressions and models and with two different occlusal reduction designs. MATERIALS AND METHODS: Two typodont mandibular first molars were prepared to receive CAD/CAM-fabricated all-ceramic crowns. Both molars were prepared to ideal crown reduction, the first with anatomical occlusal reduction (AOR) and the second with completely flat occlusal reduction (FOR)...
November 22, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29166419/combined-stereophotogrammetry-and-laser-sintered-computer-aided-milling-framework-for-an-implant-supported-mandibular-prosthesis-a-case-history-report
#9
Maria J Suarez, Iria Paisal, Veronica Rodriguez-Alonso, Carlos Lopez-Suarez
PURPOSE: This study compared the marginal gaps of computer-aided design/computer-aided manufacture (CAD/CAM)-fabricated all-ceramic crowns constructed from scanned impressions and models and with two different occlusal reduction designs. MATERIALS AND METHODS: Two typodont mandibular first molars were prepared to receive CAD/CAM-fabricated all-ceramic crowns. Both molars were prepared to ideal crown reduction, the first with anatomical occlusal reduction (AOR) and the second with completely flat occlusal reduction (FOR)...
November 22, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29166195/the-experience-of-young-women-living-in-a-prostitution-area-in-maintaining-their-reproductive-health
#10
Vonyca Dovis, Setyowati, Wiwit Kurniawati
Young women face a difficult situation when they live in a prostitution area or red light district. A phenomenological approach was applied to explore the experiences in maintaining reproductive health of 10 young women living in the prostitution area in Lampung, one of the provinces in Sumatra. Thematic content analysis found 7 themes including: (1) The participants' perception of prostitution as a place of naughty women and free sexual activity that can transmit STDs and influence adolescent psychology; (2) The ways the participants kept their reproductive organs healthy were through maintaining friendships, maintaining personal hygiene, avoiding free sexual activity, eating healthy food, and having routine medical checkups; (3) Information support was gained from family, health workers, media, and teachers; (4) Emotional support from family and friends; (5) Barriers to maintaining good health were inaccessible health facilities and an underfunded health service; (6) The needs of the participants were reproductive health services and clean environment; (7) The participants hoped for health education and intensive health services with friendly nurses...
2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/29166121/photoinduced-transformations-of-indole-and-3-formylindole-monomers-isolated-in-low-temperature-matrices
#11
Igor Reva, Leszek Lapinski, A J Lopes Jesus, Maciej J Nowak
Photochemical transformations were studied for monomers of indole and 3-formylindole isolated in low-temperature noble-gas matrices. Upon UV (λ > 270 nm) irradiation of indole trapped in argon and neon matrices, the initial 1H-form of the compound converted into the 3H-tautomer. Alongside this photoinduced hydrogen-atom transfer, an indolyl radical was also generated by photodetachment of the hydrogen atom from the N1-H bond. Excitation of 3-formylindole isolated in an argon matrix with UV (λ > 335 nm) light led to interconversion between the two conformers of the 1H-tautomer, differing from each other in the orientation of the formyl group (cis or trans)...
November 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29166097/volatility-of-the-catalytic-hydrogenation-products-of-1-4-bis-phenylethynyl-benzene
#12
Hom N Sharma, Elizabeth A Sangalang, Cheng K Saw, Gareth A Cairns, William McLean, Robert S Maxwell, Long N Dinh
Measurements of equilibrium vapor pressures by effusion thermogravimetry and melting points by differential scanning calorimetry reveal that the melting temperature and equilibrium vapor pressures of 1,4-bis(phenylethynyl)benzene (DEB) do not vary monotonically with the hydrogenation extent. Contrary to intuition which suggests increasing volatility with hydrogenation, results indicate decreasing volatility for the first two hydrogenation steps before a non-monotonic upward trend, in which trans-isomers are less volatile...
November 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29166054/modeling-super-resolution-sers-using-a-t-matrix-method-to-elucidate-molecule-nanoparticle-coupling-and-the-origins-of-localization-errors
#13
Charles W Heaps, George C Schatz
A computational method to model diffraction-limited images from super-resolution surface-enhanced Raman scattering microscopy is introduced. Despite significant experimental progress in plasmon-based super-resolution imaging, theoretical predictions of the diffraction limited images remain a challenge. The method is used to calculate localization errors and image intensities for a single spherical gold nanoparticle-molecule system. The light scattering is calculated using a modification of generalized Mie (T-matrix) theory with a point dipole source and diffraction limited images are calculated using vectorial diffraction theory...
June 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29166046/fcc-hcp-coexistence-in-dense-thermo-responsive-microgel-crystals
#14
D Karthickeyan, R G Joshi, B V R Tata
Analogous to hard-sphere suspensions, monodisperse thermo-responsive poly (N-isopropyl acrylamide) (PNIPAM) microgel particles beyond a volume fraction (ϕ) of 0.5 freeze into face centered cubic (FCC)-hexagonal close packed (HCP) coexistence under as prepared conditions and into an FCC structure upon annealing. We report here FCC-HCP coexistence to be stable in dense PNIPAM microgel crystals (ϕ > 0.74) with particles in their deswollen state (referred to as osmotically compressed microgel crystals) and the FCC structure with particles in their swollen state by performing annealing studies with different cooling rates...
June 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29166017/bond-dissociation-energies-of-tungsten-molecules-wc-wsi-ws-wse-and-wcl
#15
Andrew Sevy, Robert F Huffaker, Michael D Morse
Resonant two-photon ionization spectroscopy has been used to locate predissociation thresholds in WC, WSi, WS, WSe, and WCl, allowing bond dissociation energies to be measured for these species. Because of the high degree of vibronic congestion in the observed spectra, it is thought that the molecules dissociate as soon as the lowest separated atom limit is exceeded. From the observed predissociation thresholds, dissociation energies are assigned as D0(WC) = 5.289(8) eV, D0(WSi) = 3.103(10) eV, D0(WS) = 4.935(3) eV, D0(WSe) = 4...
November 22, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29166006/coptem-a-model-to-investigate-the-factors-driving-crude-oil-pipeline-transportation-emissions
#16
Nicolas Choquette-Levy, Margaret Zhong, Heather L MacLean, Joule A Bergerson
Previous transportation fuel life cycle assessment studies have not fully accounted for the full variability in the crude oil transport stage - e.g. transporting a light crude through a high-diameter pipeline, vs. transporting a heavy crude through a small-diameter pipeline. We develop a first principles, fluid mechanics-based crude oil pipeline transportation emissions model (COPTEM) that calculates the greenhouse gas (GHG) emissions associated with pipeline transport as a function of crude oil parameters, pipeline dimensions, and external factors...
November 22, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29165917/a-novel-multisite-confocal-system-for-rapid-ca-2-imaging-from-submicron-structures-in-brain-slices
#17
Luiza Filipis, Karima Ait Ouares, Philippe Moreau, Dimitrii Tanese, Valeria Zampini, Andrea Latini, Chun Bleau, Charlie Bleau, Jeremy Graham, Marco Canepari
In brain slices, resolving fast Ca(2+) fluorescence signals from submicron structures is typically achieved using two-photon or confocal scanning microscopy, an approach that limits the number of scanned points. The novel multiplexing confocal system presented here overcomes this limitation. This system is based on a fast spinning disk, a multimode diode laser and a novel high-resolution CMOS camera. The spinning disk, running at 20,000 rpm, has custom-designed spiral pattern that maximises light collection while rejecting out-of-focus fluorescence to resolve signals from small neuronal compartments...
November 22, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29165899/quantitative-performance-evaluation-of-a-back-illuminated-scmos-camera-with-95-qe-for-super-resolution-localization-microscopy
#18
Yujie Wang, Lingxi Zhao, Zhe Hu, Yina Wang, Zeyu Zhao, Luchang Li, Zhen-Li Huang
Scientific Complementary Metal Oxide Semiconductor (sCMOS) cameras were introduced into the market in 2009 and are now becoming a major type of commercial cameras for low-light imaging. sCMOS cameras provide simultaneously low read noise, high readout speed, and large pixel array; however, the relatively low quantum efficiency (QE) of sCMOS cameras has been a major limitation for its application in single molecule imaging, especially super-resolution localization microscopy which requires high detection sensitivity...
November 22, 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/29165872/manganese-dioxide-coated-ws2-fe3-o4-ssio2-nanocomposites-for-ph-responsive-mr-imaging-and-oxygen-elevated-synergetic-therapy
#19
Guangbao Yang, Rui Zhang, Chao Liang, He Zhao, Xuan Yi, Sida Shen, Kai Yang, Liang Cheng, Zhuang Liu
Recently, the development of multifunctional theranostic nanoplatforms to realize tumor-specific imaging and enhanced cancer therapy via responding or modulating the tumor microenvironment (TME) has attracted tremendous interests in the field of nanomedicine. Herein, tungsten disulfide (WS2 ) nanoflakes with their surface adsorbed with iron oxide nanoparticles (IONPs) via self-assembly are coated with silica and then subsequently with manganese dioxide (MnO2 ), on to which polyethylene glycol (PEG) is attached...
November 22, 2017: Small
https://www.readbyqxmd.com/read/29165857/isolation-of-phage-display-library-derived-scfv-antibody-specific-to-listeria-monocytogenes-by-a-novel-immobilized-method
#20
Nguyen Xuan-Hung, Thu-Le Trinh, Huong Thi-Bich Vu, Huan Quang Le, Anh To Kim
AIMS: To select Listeria monocytogenes specific scFv antibodies from a phage display library by a novel simple and cost-effective immobilization method. METHODS AND RESULTS: Light Expanded Clay Aggregate (LECA) was used as biomass support matrix for biopanning of a phage display library to select Listeria monocytogenes specific scFv antibody. Four rounds of positive selection against LECA-immobilized L. monocytogenes and an additional subtractive panning against L...
November 22, 2017: Journal of Applied Microbiology
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