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https://www.readbyqxmd.com/read/28926794/depression-recognition-according-to-heart-rate-variability-using-bayesian-networks
#1
Danni Kuang, Rongqian Yang, Xiuwen Chen, Guohui Lao, Fengchun Wu, Xiong Huang, Ruixue Lv, Lei Zhang, Chuanxu Song, Shanxing Ou
BACKGROUND: Doctors mainly use scale tests and subjective judgment in the clinical diagnosis of depression. Researches have demonstrated that depression is associated with the dysfunction of the autonomic nervous system (ANS), where its modulation can be evaluated by heart rate variability (HRV). Depression patients have lower HRV than healthy subjects. Therefore, HRV may be used to distinguish depression patients from healthy people. METHODS: HRV signals were collected from 76 female subjects composed of 38 depression patients and 38 healthy people...
September 11, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28926033/working-towards-consensus-the-need-for-coordinated-policies-to-assist-control-of-foot-and-mouth-disease-and-emerging-disease-threats-in-south-east-asia
#2
I W Patrick, S Sovann, S Socheat
Foot and mouth disease (FMD) is an important transboundary disease in South-East Asia. Its control has been a priority in the region for at least 20 years, with extensive institutional support and capacity-building being provided by the international community through the World Organisation for Animal Health. This paper describes the FMD control and eradication programme in the Mekong region (Myanmar, Thailand, the Lao People's Democratic Republic, Cambodia and Vietnam) of South-East Asia and evaluates the FMD control programme in one of the region's countries, namely Cambodia...
April 2017: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28922638/reverse-flow-injection-spectrophotometric-determination-of-ciprofloxacin-in-pharmaceuticals-using-iron-from-soil-as-a-green-reagent
#3
Sysay Palamy, Wirat Ruengsitagoon
A novel reverse flow injection spectrophotometric method for the determination of ciprofloxacin was successfully combined with the on-line introduction of an iron solution extracted from soil as green reagent. The assay was optimized by a univariate method to select the optimum conditions for the highest absorbance and highest stability of the complex. Beer-Lambert's law (λmax=440nm) is obeyed in the range 0.5-50μgmL(-1) with a correlation coefficient (r(2)) of 0.9976 and 0.9996 using soil as green reagent from Khon Kaen, Thailand and Vientiane, Laos, respectively...
September 13, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28920775/laparoscopic-assisted-insertion-of-a-ventriculoperitoneal-shunt-in-a-rescued-asiatic-black-bear-ursus-thibetanus-in-laos
#4
Romain Pizzi, Jonathan Mark Cracknell, Andrew C Kitchener, Nev Broadis, Denise Laughlin, Kirsty Officer, Yolanda Martinez Pereira, Matt Hunt
A 3-yr-old Asiatic black bear (Ursus thibetanus), weighing 68 kg, underwent a laparoscopic-assisted placement of a ventriculoperitoneal shunt for hydrocephalus in the Lao People's Democratic Republic. Rescued as a young cub with a notably domed head, the bear's condition had deteriorated with age, but euthanasia was not a viable option because of cultural issues. Surgery was attempted as a palliative measure. The bear had ventrally orientated crossed eyes (abducens nerve palsy and dorsal midbrain syndrome), papilledema, severe rhinorrhea, depressed mentation, lethargy, a very poor appetite, and was stunted...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28916916/investigating-baseline-red-meat-slaughter-operator-capacity-and-directions-for-development-in-lao-pdr
#5
Joanne C Thomas, James R Young, Kathrin Schemann, Phaivanh Chankhamthong, Syseng Khounsy, Sonevilay Nampanya, Peter A Windsor, Russell D Bush
A study of operator knowledge, attitudes and practices (KAP) in red meat slaughter premise operations in northern Laos was conducted and compared with international best practice, to inform future industry development. The survey interviewed 68 (of 94 possible participants) employees from all ten commercial slaughter premises in six districts in three northern Laos provinces. This was supported by observations of slaughter premises, processes and the conduct of personnel. Descriptive analysis and linear regression modelling identified significant KAP predictor factors, and a gap analysis supported or rejected inferences from the generally low KAP scores for human and animal health, animal welfare, good manufacturing practices (GMP), work conditions and economics...
September 15, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28916366/measuring-progress-and-projecting-attainment-on-the-basis-of-past-trends-of-the-health-related-sustainable-development-goals-in-188-countries-an-analysis-from-the-global-burden-of-disease-study-2016
#6
(no author information available yet)
BACKGROUND: The UN's Sustainable Development Goals (SDGs) are grounded in the global ambition of "leaving no one behind". Understanding today's gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016), we measured 37 of the 50 health-related SDG indicators over the period 1990-2016 for 188 countries, and then on the basis of these past trends, we projected indicators to 2030...
September 8, 2017: Lancet
https://www.readbyqxmd.com/read/28916173/a-new-anatomical-view-on-the-vector-cardiogram-the-mean-temporal-spatial-isochrones
#7
Peter M van Dam
AIM: This proof of principle study aims to show the direct relationship between cardiac anatomy and the mean cardiac activation path as captured by the 12 lead ECG derived mean temporal-spatial isochrones (mean TSI) path. METHODS: To obtain the mean TSI signal a vector cardiographic (VCG) signal is constructed from the 12 lead ECG. The construction of the VCG signal uses a model of the heart and torso with patient specific electrode extracted from a 3D photo. The propagation of the activation through the heart is captured by estimating the mean of a cardiac activation isochrone using this VCG signal...
August 12, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28914184/elements-of-effective-community-engagement-lessons-from-a-targeted-malaria-elimination-study-in-lao-pdr-laos
#8
Bipin Adhikari, Christopher Pell, Koukeo Phommasone, Xayaphone Soundala, Palingnaphone Kommarasy, Tiengkham Pongvongsa, Gisela Henriques, Nicholas P J Day, Mayfong Mayxay, Phaik Yeong Cheah
BACKGROUND: Mass drug (antimalarial) administration (MDA) is currently under study in Southeast Asia as part of a package of interventions referred to as targeted malaria elimination (TME). This intervention relies on effective community engagement that promotes uptake and adherence in target communities (above 80%). OBJECTIVE: Based on the experienced of designing and implementing the community engagement for TME in Laos, in this article we aim to present the elements of effective community engagement for mass antimalarial administration...
2017: Global Health Action
https://www.readbyqxmd.com/read/28904259/prevalence-and-risk-factors-of-needle-stick-and-sharp-injury-among-tertiary-hospital-workers-vientiane-lao-pdr
#9
Chieko Matsubara, Kayako Sakisaka, Vanphanom Sychareun, Alongkone Phensavanh, Moazzam Ali
ObjectivesHealth care workers (HCWs) face risks of needle stick and sharp injuries (NSIs). Most NSIs occur in developing countries, however, no epidemiological study on NSIs is publicly available in Lao PDR. The objective of this study is to identify the prevalence and risk factors of NSIs among HCWs in Lao PDR.MethodsThis cross-sectional study was designed to determine the prevalence and risk factors of NSIs among four tertiary hospitals in Vientiane, Lao People's Democratic Republic.ResultsSix months before the survey, 11...
September 13, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/28899535/efficacy-and-safety-of-acupuncture-treatment-on-primary-insomnia-a%C3%A2-randomized-controlled-trial
#10
Xuan Yin, Minghui Gou, Jian Xu, Bo Dong, Ping Yin, Fernand Masquelin, Junyi Wu, Lixing Lao, Shifen Xu
OBJECTIVE: The objective of this study was to evaluate the efficacy and safety of acupuncture treatment for primary insomnia. METHODS: We conducted a single-center, single-blinded, and randomized controlled clinical trial. Seventy-two patients with primary insomnia were randomly assigned into two groups - the acupuncture group, who received acupuncture treatment, and the control group, who received sham acupuncture treatment. The treatment was given three times a week for four weeks...
September 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28891631/design-and-fabrication-of-an-all-solid-state-polymer-supercapacitor-with-highly-mechanical-flexibility-based-on-polypyrrole-hydrogel
#11
Limin Zang, Qifan Liu, Jianhui Qiu, Chao Yang, Chun Wei, Chanjuan Liu, Li Lao
A conducting polymer-based hydrogel (PPy/CPH) with a polypyrrole-poly(vinyl alcohol) interpenetrating network was prepared by utilization of a chemical cross-linked poly(vinyl alcohol)-H2SO4 hydrogel (CPH) film as flexible substrate followed by vapor-phase polymerization of pyrrole. Then an all-solid-state polymer supercapacitor (ASSPS) was fabricated by sandwiching the CPH film between two pieces of the PPy/CPH film. The ASSPS is mechanically robust and flexible with a tensile strength of 20.83 MPa and a break elongation of 377% which is superior to other flexible conducting polymer hydrogel-based supercapacitors owing to the strong hydrogen bonding interactions among the layers and the high mechanical properties of the PPy/CPH...
September 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28891102/co-oxidation-by-group-3-metal-monoxide-cations-supported-on-fe-co-4-2
#12
Mingfei Zhou, Chaoxian Chi, Hui Qu, Luyan Meng, Fanchen Kong, Mingbiao Luo
Infrared photodissociation spectroscopy of anions in the form of OMFe(CO)5- (M=Sc, Y, La) indicates that all these anions involve an 18-electron [Fe(CO)4]2- building block that is bonded with the M center through two bridged carbonyl ligands. The OLaFe(CO)5- anion is determined to be a CO-tagged complex involving a [Fe(CO)4]2-[LaO]+ anion core. In contrast, the OYFe(CO)5- anion is characterized to have a [Fe(CO)4]2-[Y(η2-CO2)]+ structure involving a side-on bonded CO2 ligand. The CO-tagged complex and the [Fe(CO)4]2-[Sc(η2-CO2)]+ isomer co-exist for the OScFe(CO)5- anion...
September 10, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28889792/overall-survival-with-combined-nivolumab-and-ipilimumab-in-advanced-melanoma
#13
Jedd D Wolchok, Vanna Chiarion-Sileni, Rene Gonzalez, Piotr Rutkowski, Jean-Jacques Grob, C Lance Cowey, Christopher D Lao, John Wagstaff, Dirk Schadendorf, Pier F Ferrucci, Michael Smylie, Reinhard Dummer, Andrew Hill, David Hogg, John Haanen, Matteo S Carlino, Oliver Bechter, Michele Maio, Ivan Marquez-Rodas, Massimo Guidoboni, Grant McArthur, Celeste Lebbé, Paolo A Ascierto, Georgina V Long, Jonathan Cebon, Jeffrey Sosman, Michael A Postow, Margaret K Callahan, Dana Walker, Linda Rollin, Rafia Bhore, F Stephen Hodi, James Larkin
Background Nivolumab combined with ipilimumab resulted in longer progression-free survival and a higher objective response rate than ipilimumab alone in a phase 3 trial involving patients with advanced melanoma. We now report 3-year overall survival outcomes in this trial. Methods We randomly assigned, in a 1:1:1 ratio, patients with previously untreated advanced melanoma to receive nivolumab at a dose of 1 mg per kilogram of body weight plus ipilimumab at a dose of 3 mg per kilogram every 3 weeks for four doses, followed by nivolumab at a dose of 3 mg per kilogram every 2 weeks; nivolumab at a dose of 3 mg per kilogram every 2 weeks plus placebo; or ipilimumab at a dose of 3 mg per kilogram every 3 weeks for four doses plus placebo, until progression, the occurrence of unacceptable toxic effects, or withdrawal of consent...
September 11, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28887854/human-tissue-inhibitor-of-metalloproteinases-1-improved-wound-healing-in-diabetes-through-its-anti-apoptotic-effect
#14
Guojuan Lao, Meng Ren, Xiaoyi Wang, Jinglu Zhang, Yanrui Huang, Dan Liu, Hengcong Luo, Chuan Yang, Li Yan
Impaired wound healing accompanies severe cell apoptosis in diabetic patients. Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) was known to have effects on promoting growth and anti-apoptosis for cells. we aimed to determine the actual levels of TIMP-1 and cell apoptosis in: 1) the biopsies of diabetic and non-diabetic foot tissue; 2) the human fibroblasts with or without treatments of Advanced Glycation End Products (AGEs). Next, in both human fibroblasts and the animal model of diabetic rats, to determine the improved levels of cell apoptosis and wound healing after the treatments of either active protein of TIMP-1 or in vivo expression of gene therapy vector-mediated TIMP-1...
September 8, 2017: Experimental Dermatology
https://www.readbyqxmd.com/read/28884877/self-administered-acupressure-for-insomnia-disorder-a-pilot-randomized-controlled-trial
#15
Wing-Fai Yeung, Fiona Yan-Yee Ho, Ka-Fai Chung, Zhang-Jin Zhang, Branda Yee-Man Yu, Lorna Kwai-Ping Suen, Lily Ying-Tung Chan, Hai-Yong Chen, Lai-Ming Ho, Li-Xing Lao
Self-administered acupressure has potential as a low-cost alternative treatment for insomnia. To evaluate the short-term effects of self-administered acupressure for alleviating insomnia, a pilot randomized controlled trial was conducted. Thirty-one subjects (mean age: 53.2 years; 77.4% female) with insomnia disorder were recruited from a community. The participants were randomized to receive two lessons on either self-administered acupressure or sleep hygiene education. The subjects in the self-administered acupressure group (n = 15) were taught to practise self-administered acupressure daily for 4 weeks...
September 8, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28882517/diagnosis-and-genetic-analysis-of-the-worldwide-distributed-rattus-borne-trypanosoma-herpetosoma-lewisi-and-its-allied-species-in-blood-and-fleas-of-rodents
#16
Paola A Ortiz, Herakles A Garcia, Luciana Lima, Flávia Maia da Silva, Marta Campaner, Carlos L Pereira, Sathaporn Jittapalapong, Luis Neves, Marc Desquesnes, Erney P Camargo, Marta M G Teixeira
Trypanosoma (Herpetosoma) lewisi is a cosmopolitan parasite of rodents strongly linked to the human dispersal of Rattus spp. from Asia to the rest of the world. This species is highly phylogenetically related to trypanosomes from other rodents (T. lewisi-like), and sporadically infects other mammals. T. lewisi may opportunistically infect humans, and has been considered an emergent rat-borne zoonosis associated to poverty. We developed the THeCATL-PCR based on Cathepsin L (CATL) sequences to specifically detect T...
September 4, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28880929/correction-floristic-characteristics-and-affinities-in-lao-pdr-with-a-reference-to-the-biogeography-of-the-indochina-peninsula
#17
https://www.readbyqxmd.com/read/28878435/assessment-of-knowledge-about-snakebite-management-amongst-healthcare-providers-in-the-provincial-and-two-district-hospitals-in-savannakhet-province-lao-pdr
#18
Vongphoumy Inthanomchanh, Joshua A Reyer, Joerg Blessmen, Ketkesone Phrasisombath, Eiko Yamamoto, Nobuyuki Hamajima
Snakebite is a neglected condition and a common public health problem in Lao People's Democratic Republic (Lao PDR), with a high incidence of up to 1,105 cases per 100,000 persons per year. Snakebite patients with systemic envenoming do not receive effective treatment at local health facilities. Healthcare providers have only limited knowledge in assessing and providing the correct treatment for venomous snakebites. A cross-sectional study was conducted among 119 healthcare providers in Savannakhet Province, Lao PDR, with respect to their socio-demographic characteristics, knowledge of snake identification, and management of snakebite...
August 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28878405/some-sustained-improvements-in-pneumonia-case-management-four-and-five-years-following-implementation-of-paediatric-hospital-guidelines-in-lao-pdr
#19
Amy Gray, Louis Chhor, Saysanasongkham Sanyalack, Ruth Lim, Jana Lai, Keo Vilivong, Melinda Morpeth, Douangdao Soukaloun, Fiona Russell
In 2010, WHO paediatric hospital guidelines were implemented in Lao PDR, along with training workshops and feedback audits, achieving significant improvements in pneumonia case management when assessed one-year post-intervention. The sustainability of these improvements is hereby assessed, four and five years post-intervention. Medical records of children aged 1-59 months, diagnosed with pneumonia in 2010, 2011, 2014 and 2015 from a central Lao hospital were reviewed. Information relating to clinical steps in pneumonia case management was extracted and a scoring system applied based on the documentation of each clinical step, producing a pneumonia assessment score for each case...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28875553/human-brain-imaging-of-nicotinic-acetylcholine-%C3%AE-4%C3%AE-2-receptors-using-18-f-nifene-selectivity-functional-activity-toxicity-aging-effects-gender-effects-and-extrathalamic-pathways
#20
Jogeshwar Mukherjee, Patrick J Lao, Tobey J Betthauser, Gurleen K Samra, Min-Liang Pan, Ishani H Patel, Christopher Liang, Raju Metherate, Bradley T Christian
Nicotinic acetylcholinergic receptors (nAChR's) have been implicated in several brain disorders, including addiction, Parkinson's disease, Alzheimer's disease and schizophrenia. Here we report in vitro selectivity and functional properties, toxicity in rats, in vivo evaluation in humans, and comparison across species of [(18) F]Nifene, a fast acting PET imaging agent for α4β2* nAChRs. Nifene had subnanomolar affinities for hα2β2 (0.34 nM), hα3β2 (0.80 nM) and hα4β2 (0.83 nM) nAChR but weaker (27 to 219 nM) for hβ4 nAChR subtypes and 169 nM for hα7 nAChR...
September 5, 2017: Journal of Comparative Neurology
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