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Sengchanh Kounnavong, Khouanchay Soundavong, Syda Xayavong, Nialoun Vongpraserth, Phongsavang Bounsavath, Souphatsone Houatthongkham, Bounfeng Phoummalaysith, Yu Mon Saw, Eiko Yamamoto, Kenji Toba, Nobuyuki Hamajima
With the aging of society, the number of elderly with reduced cognitive function has been increasing worldwide. As a test to measure the cognitive function, the Revised Hasegawa's Dementia Scale (HDS-R) has been used in Japan, Korea, and China. Since there was no HDS-R version for Laotians, the questionnaire and manual were developed through the cooperation of Lao and Japanese researchers. Back-translation was conducted to confirm the accuracy of the translation. The score on the 9-item HDS-R ranges 0 to 30 points, and reduced cognitive function is usually defined as a score of 20 points or lower...
February 2017: Nagoya Journal of Medical Science
Wittaya Jomoui, Goonnapa Fucharoen, Kanokwan Sanchaisuriya, Patnaree Charoenwijitkul, Jitpanu Maneesarn, Xiangmin Xu, Supan Fucharoen
α(0)-thalassemia of SEA deletion (-(SEA)) is common among Southeast Asian and Chinese. Using haplotype and phylogenetic analyses, we examined the origin of this defect in Southeast Asian populations. Study was done on both normal and α(0)-thalassemia alleles in 3 ethnic groups including 96 Thai, 52 Laotian and 21 Cambodian. Five SNPs encompassing the (-(SEA)) including (rs3760053 T>G), (rs1211375 A>C), (rs3918352 A>G), (rs1203974 A>G) and (rs11248914 C>T) were examined using high-resolution melting assays...
April 6, 2017: Journal of Human Genetics
Savina Vorasane, Masamine Jimba, Kimiyo Kikuchi, Junko Yasuoka, Keiko Nanishi, Jo Durham, Vanphanom Sychareun
BACKGROUND: Despite global efforts, HIV-related stigma continues to negatively impact the health and well-being of people living with HIV/AIDS. Even in healthcare settings, people with HIV/AIDS experience discrimination. Anecdotal evidence suggests that healthcare professionals in the Lao People's Democratic Republic, a lower-middle income country situated in Southeast Asia, stigmatize HIV/AID patients. The purpose of this study was to assess HIV stigmatizing attitudes within Laotian healthcare service providers and examine some of the factors associated with HIV/AIDS-related stigma among doctors and nurses...
February 10, 2017: BMC Health Services Research
Soulasack Vannamahaxay, Souliya Vongkhamchanh, Montira Intanon, Sahatchai Tangtrongsup, Saruda Tiwananthagorn, Kidsadagon Pringproa, Phongsakorn Chuammitri
The global emergence of canine parvovirus type 2c (CPV-2c) has been well documented. In the present study, 139 rectal swab samples collected from diarrheic dogs living in Vientiane, Laos, in 2016 were tested for the presence of the canine parvovirus (CPV) VP2 gene by PCR. The results showed that 82.73% (115/139) of dogs were CPV positive by PCR. The partial VP2 gene was sequenced in 94 of the positive samples; 91 samples belonged to CPV-2c (426Glu) subtype, while 3 samples belonged to the CPV-2a (426Asn) subtype...
May 2017: Archives of Virology
Yi Qian, Fei Yan, Wei Wang, Shayna Clancy, Kongsap Akkhavong, Manithong Vonglokham, Somphou Outhensackda, Truls Østbye
BACKGROUND: The Lao People's Democratic Republic is facing a critical shortage and maldistribution of health workers. Strengthening of the health workforce has been adopted as one of the five priorities of the National Health Sector Strategy (2013-2025). This study aims to identify, explore, and better understand the key challenges for strengthening the Laotian health workforce. METHODS: This study applied exploratory and descriptive qualitative methods and adapted a working life-span framework...
November 29, 2016: Human Resources for Health
Susan L Stewart, Sandy L Kwong, Christopher L Bowlus, Tung T Nguyen, Annette E Maxwell, Roshan Bastani, Eric W Chak, Moon S Chen
AIM: To describe racial/ethnic differences in treatment and survival among liver cancer patients in a population-based cancer registry. METHODS: Invasive cases of primary hepatocellular carcinoma, n = 33270, diagnosed between January 1, 1988-December 31, 2012 and reported to the California Cancer Registry were analyzed by race/ethnicity, age, gender, geographical region, socio-economic status, time period of diagnosis, stage, surgical treatment, and survival. Patients were classified into 15 racial/ethnic groups: non-Hispanic White (White, n = 12710), Hispanic (n = 8500), Chinese (n = 2723), non-Hispanic Black (Black, n = 2609), Vietnamese (n = 2063), Filipino (n = 1479), Korean (n = 1099), Japanese (n = 658), American Indian/Alaskan Native (AIAN, n = 281), Laotian/Hmong (n = 244), Cambodian (n = 233), South Asian (n = 190), Hawai`ian/Pacific Islander (n = 172), Thai (n = 95), and Other Asian (n = 214)...
October 14, 2016: World Journal of Gastroenterology: WJG
Alina Kutsenko, Maya R Ladenheim, Nathan Kim, Pauline Nguyen, Vincent Chen, Channa Jayasekera, Ju Dong Yang, Radhika Kumari, Lewis Roberts, Mindie H Nguyen
BACKGROUND: We used metabolic risk factors to estimate the prevalence and clinical significance of nonalcoholic fatty liver disease in Asian Americans with hepatocellular carcinoma (HCC). METHODS: This is a retrospective cohort study of 824 consecutive Asian HCC patients at Stanford University Medical Center from 1998 to 2015. Patients were subdivided as: Chinese, other East Asian (Japanese and Korean), South East Asian (Vietnamese, Thai, and Laotian), Maritime South East Asian (MSEA: Malaysian, Indonesian, Filipino, and Singaporean), and South West Asian (Indian, Pakistani, and Middle Eastern)...
September 15, 2016: Journal of Clinical Gastroenterology
Viengvaly Phommanivong, Seiji Kanda, Takaki Shimono, Pheophet Lamaningao, Andrew Waleluma Darcy, Nobuyuki Mishima, Bounthanh Phaytanavanh, Toshimasa Nishiyama
BACKGROUND: During the 2013 outbreak, 4638 infection cases and 32 deaths have been recorded in the southern part of Laos. In recent years, the chikungunya virus (CHIKV) emerged in the part of the country bordering Cambodia. Dengue virus (DENV) and CHIKV are transmitted by common mosquito vectors. Both diseases have similar clinical presentations; therefore, CHIKV infections might go undiagnosed in DENV-endemic areas. Thus, rapid detection and accurate diagnosis are crucial for differentiating between the two viruses (DENV and CHIKV)...
2016: Tropical Medicine and Health
Daisuke Kaya, Masahide Yoshikawa, Toshiya Nakatani, Fumimasa Tomo-Oka, Yuki Fujimoto, Koji Ishida, Yukihisa Fujinaga, Yosuke Aihara, Shinsaku Nagamatsu, Eijo Matsuo, Masaharu Tokoro, Yukiteru Ouji, Eiryo Kikuchi
Ancylostoma (A.) ceylanicum, one of the most common species of hookworms infecting dogs and cats, also causes patent infections in humans and is now considered to be the second most common hookworm species infecting populations in southeast Asia. A Japanese patient who returned from a visit to Thailand and Lao People's Democratic Republic (PDR) was presented with intermittent watery diarrhea with eosinophilia. Hookworm eggs were found in feces samples, and adult worms were confirmed to be present in the jejunum with capsule endoscopy and double balloon enteroscopy...
December 2016: Parasitology International
Edwin Chandrasekar, Karen E Kim, Sharon Song, Ranjana Paintal, Michael T Quinn, Helen Vallina
The health insurance coverage established by the Patient Protection and Affordable Care Act has created an opportunity to reduce racial/ethnic disparities in healthcare. It is expected that of the 24 million individuals projected to join, nearly one-half will be non-white and one-fourth will speak a language other than English at home. Asian Americans are one of the fastest growing racial/ethnic groups in the USA. The majority are foreign born and experience limited English proficiency. The role of navigators has been shown to increase enrollment rates of public insurance programs...
September 2016: Journal of Racial and Ethnic Health Disparities
Chanintorn Chaitraiphop, Kanokwan Sanchaisuriya, Sakoun Inthavong, Goonnapa Fucharoen, Pattara Sanchaisuriya, Yossombut Changtrakun, Supan Fucharoen
BACKGROUND: To evaluate the use of MCV and MCH cutoffs for thalassemia screening in areas with a high frequency of thalassemia and hemoglobinopathies using different hematology analyzers. METHODS: Blood samples of known α(0)-thalassemia and β-thalassemia carriers were analyzed to establish the appropriate cutoffs for each analyzer. These selected cutoffs were validated prospectively for screening of α-thalassemia, β-thalassemia in combination with the dichlorophenolindophenol test for hemoglobin E on another 288 Thai and 325 Laotian students...
2016: Clinical Laboratory
Florence Richard, Michèle Gerbault-Seureau, Bounneuang Douangboupha, Kham Keovichit, Jean-Pierre Hugot, Bernard Dutrillaux
Laonastes aenigmamus (Khanyou) is a recently described rodent species living in geographically separated limestone formations of the Khammuan Province in Lao PDR. Chromosomes of 21 specimens of L. aenigmamus were studied using chromosome banding as well as fluorescent in situ hybridization (FISH) techniques using human painting, telomere repeats, and 28S rDNA probes. Four different karyotypes were established. Study with human chromosome paints and FISH revealed that four large chromosomes were formed by multiple common tandem fusions, with persistence of some interstitial telomeres...
September 2016: Chromosome Research
Kaoru Midorikawa, Douangdao Soukaloun, Kongsap Akkhavong, Bouavanh Southivong, Oudayvone Rattanavong, Vikham Sengkhygnavong, Amphay Pyaluanglath, Saymongkhonh Sayasithsena, Satoshi Nakamura, Yutaka Midorikawa, Mariko Murata
BACKGROUND: Increasing age is associated with elevated risk of non-communicable diseases, including dementia and Alzheimer's disease (AD). The apolipoprotein E (APOE) ε4 allele is a risk factor not only for AD, but also for cognitive decline, depressive symptoms, stroke, hypertension, coronary heart disease, cardiovascular disease, and diabetes. The Lao People's Democratic Republic (Laos) is undergoing development; consequently, life expectancy has risen. To evaluate the future risk of non-communicable diseases, we investigated APOE genotypes and anthropometric characteristics in the Laotian population...
2016: PloS One
Matthias Sipiczki, Walter P Pfliegler, Silvana V B Safar, Paula B Morais, Carlos A Rosa
Four strains alternating between yeast and filamentous growth morphologies were isolated from flowers in two regions of Laos. In liquid environment the isolates propagated by budding and developed irregularly shaped pseudohyphae. On solid media, their yeast cells switched to hyphal growth which could return to the yeast phase by developing lateral blastoconidia. The sequences of the D1/D2 domains of the large subunit (LSU) 26S rRNA genes, the internal transcribed spacer (ITS) regions and the small subunit (SSU) 18S rRNA genes were identical in the four strains and differed from the corresponding sequences of other yeast species available in databases by at least 11 % (D1/D2), 13 % (ITS) and 7 % (SSU)...
July 2016: International Journal of Systematic and Evolutionary Microbiology
Lachlan David Mailey Farmer, Soo Khai Ng, Adam Rudkin, Jamie Craig, Dechen Wangmo, Hughie Tsang, Khamphoua Southisombath, Andrew Griffiths, James Muecke
PURPOSE: To determine and compare the major causes of childhood blindness and severe visual impairment in Bhutan and Laos. DESIGN: Independent cross-sectional surveys. METHODS: This survey consists of 2 cross-sectional observational studies. The Bhutanese component was undertaken at the National Institute for Vision Impairment, the only dedicated school for the blind in Bhutan. The Laotian study was conducted at the National Ophthalmology Centre and Vientiane School for the Blind...
November 2015: Asia-Pacific Journal of Ophthalmology
Wittaya Jomoui, Goonnapa Fucharoen, Kanokwan Sanchaisuriya, Van Hoa Nguyen, Supan Fucharoen
BACKGROUND: Hemoglobin Constant Spring (Hb CS) is an abnormal Hb caused by a mutation at the termination codon of α2-globin gene found commonly among Southeast Asian and Chinese people. Association of Hb CS with α°-thalassemia leads to a thalassemia intermedia syndrome commonly encountered in the region. We report chromosome background and addressed genetic origins of Hb CS observed in a large cohort of Hb CS among Southeast Asian populations. MATERIALS AND METHODS: A study was done on 102 Vietnamese (aged 15-49 year-old) and 40 Laotian (aged 18-39 year-old) subjects with Hb CS and results compared with 120 Hb CS genes in Thailand...
2015: PloS One
Taehoon Kim, Ethan T Nguyen, Elaine J Yuen, Thoai Nguyen, Rorng Sorn, Giang T Nguyen
BACKGROUND: There is little empirical evidence on the effects of social connectedness on geriatric depression for Southeast Asians. Studies have rarely examined interethnic differences in the resilience factors for depression in this diverse population. Greater understanding is needed as the number of older Southeast Asians in the United States increases. OBJECTIVES: We sought to examine the association between social connectedness and depressive symptoms in Vietnamese, Laotian, and Cambodian elders...
2015: Progress in Community Health Partnerships: Research, Education, and Action
Kasama Wongprachum, Kanokwan Sanchaisuriya, Maneelay Dethvongphanh, Boualay Norcharoen, Bousanit Htalongsengchan, Virack Vidamaly, Pattara Sanchaisuriya, Supan Fucharoen, Goonnapa Fucharoen, Frank P Schelp
BACKGROUND AND AIMS: A pilot screening program for thalassemia was initiated in the Lao People's Democratic Republic. This study aimed to describe the genotype diversity and hematologic features of thalassemia among the participating pregnant women. METHODS: Blood samples of 411 pregnant Laotian women were collected. Hemoglobin (Hb) profiles were determined using a capillary zone electrophoresis system. Mutations of α- and β-globin genes were investigated using a polymerase chain reaction and related techniques...
2016: Acta Haematologica
Kunihito Matsumoto, Souksavanh Vongsa, Ichiro Nakajima, Ken-Ichiro Ejima, Kiyomi Kohinata, Toshihiro Suzuki, Shigeharu Hosono, Hirofumi Aboshi, Fumiyuki Kuwata, Kichibee Otsuka
As part of quality assessment of a teleradiology program we evaluated the validity of patient information received, the quality of panoramic radiography imaging in Laos, and the ability of a Laotian radiologist to detect temporomandibular joint abnormalities. The amount of patient information gathered from 2,021 scans of panoramic radiographs was evaluated by triage before image diagnosis. Among the radiographs from 2,021 patients, primary triage indicated that there was insufficient information for 794 (39...
September 2015: Journal of Oral Science
Gui-Qiang Huang, Francesco Vitali
Eryssamena was erected by Bates (1884) based on three species E. saperdina, E. acuta and E. spinidorsis, which Breuning (1977) recognised to be the same species: Eryssamena saperdina Bates, 1884. Although Eryssamena had been accepted as an independent genus for a long time, Kusama & Takakuwa (1984) and Hashimoto (2008) considered it as a subgenus of Rondibilis Thomson, 1857. Holzschuh (2003) treated Eryssamena as a synonym of the nominotypical subgenus. Ohbayashi & Niisato (2007) and Löbl & Smetana (2010) considered Eryssamena as a synonym of Rondibilis...
July 2, 2015: Zootaxa
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