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https://www.readbyqxmd.com/read/29166462/effects-of-an-alternating-work-shift-on-air-traffic-controllers-and-the-relationship-with-excessive-daytime-sleepiness-and-stress
#1
Ângela M Freitas, Mirna Wetters Portuguez, Thaís Russomano, Marcos de Freitas, Silvio Luis da Silva Silvello, Jaderson Costa da Costa
OBJECTIVE: To evaluate symptoms of stress and excessive daytime sleepiness (EDS) in air traffic control (ATC) officers in Brazil. METHODS: Fifty-two ATC officers participated, based at three air traffic control units, identified as A, B and C. Stress symptoms were assessed using the Lipp Inventory of Stress Symptoms for Adults, and EDS by the Epworth Sleepiness Scale. RESULTS: The sample mean age was 37 years, 76.9% of whom were male. Excessive daytime sleepiness was identified in 25% of the ATC officers, with 84...
October 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29166434/evidence-hierarchies-relating-to-hand-surgery-current-status-and-improvement-a-bibliometric-analysis-study
#2
Thaís Silva Barroso, Marcelo Cortês Cavalcante, João Baptista Gomes Dos Santos, João Carlos Belloti, Flávio Faloppa, Vinícius Ynoe de Moraes
BACKGROUND: Hierarchy of evidence is an important measurement for assessing quality of literature. Information regarding quality of evidence within the Brazilian hand surgery setting is sparse, especially regarding whether research has improved in either quality or quantity. This study aimed to identify and classify hand surgery studies published in the two most important Brazilian orthopedics journals based on hierarchy of evidence, with comparisons with previously published data. DESIGN AND SETTING: Bibliometric analysis study performed in a federal university...
November 17, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29165881/nerve-injury-associated-with-high-intensity-focused-ultrasound-a-case-report
#3
Angkana Sathaworawong, Rungsima Wanitphakdeedecha
Skin laxity is a common cosmetic concern in middle-aged women. High-intensity focused ultrasound (HIFU) is one of noninvasive modalities that provides safe and effective improvement in skin laxity and tightening with minimal adverse effects. Concerning an extensive use of HIFU for facial rejuvenation, dermatologists should be aware of potential adverse effects of HIFU treatment. We herein present a case of 33-year-old Thai female with facial nerve injury after HIFU treatment for skin laxity.
November 22, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29165357/new-metabolites-of-coumarin-detected-in-human-urine-using-ultra-performance-liquid-chromatography-quadrupole-time-of-flight-tandem-mass-spectrometry
#4
Letícia Paula Leonart, João Cleverson Gasparetto, Flávia Lada Degaut Pontes, Letícia Bonancio Cerqueira, Thais Martins Guimarães de Francisco, Roberto Pontarolo
Coumarin (1,2-benzopyrone) is a natural compound whose metabolism in humans was established in the 1970s. However, a new metabolite was recently identified in human plasma, indicating that the metabolism of coumarin has not been completely elucidated. To complement the knowledge of its metabolism, a rapid and sensitive method using UPLC-QTOF-MS was developed. A total of 12 metabolites was identified using MetaboLynxTM software, including eight metabolites not previously reported in human urine. The identified biotransformation included hydroxylation, glucuronidation, sulfation, methylation, and conjugation with N-acetylcysteine...
November 22, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29165324/in-vivo-evaluation-of-modified-silk-fibroin-scaffolds-with-a-mimicked-microenvironment-of-fibronectin-decellularized-pulp-tissue-for-maxillofacial-surgery
#5
Thanh H Thai, Thongchai Nuntanaranont, Suttatip Kamolmatyakul, Jirut Meesane
This study aimed to carry out in vivo testing of the formation of new bone by modified silk fibroin scaffolds with a mimicked microenvironment of fibronectin/decellularized pulp in bone defects. Silk fibroin scaffolds were fabricated into three-dimensional scaffolds before being coated with fibronectin/decellularized pulp. The coated scaffolds were implanted into rabbits. Twenty-four bicortical calvarial defects in 12 rabbits were divided randomly into two groups: non-coated and coated silk fibroin scaffolds...
November 22, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/29164279/elemental-concentrations-in-roadside-dust-along-two-national-highways-in-northern-vietnam-and-the-health-risk-implication
#6
Thai Ha Phi, Pham Minh Chinh, Doan Danh Cuong, Luong Thi Mai Ly, Nguyen Van Thinh, Phong K Thai
There is a need to assess the risk of exposure to metals via roadside dust in Vietnam where many people live along the road/highways and are constantly exposed to roadside dust. In this study, we collected dust samples at 55 locations along two major Highways in north-east Vietnam, which passed through different land use areas. Samples were sieved into three different particle sizes and analyzed for concentrations of eight metals using a X-ray fluorescence instrument. The concentrations and environmental indices (EF, I geo) of metals were used to evaluate the degree of pollution in the samples...
November 21, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29164277/high-prevalence-of-dengue-antibodies-and-the-arginine-variant-of-the-fc%C3%AE-riia-polymorphism-in-asymptomatic-individuals-in-a-population-of-minas-gerais-state-southeast-brazil
#7
Anna Carolina Toledo da Cunha Pereira, Tatiane Ribeiro de Siqueira, Andressa Anunciação de Oliveira Prado, Camila Almeida Veiga da Silva, Thaís de Fátima Silva Moraes, Alan Alex Aleixo, José Carlos de Magalhaes, Gabriel Augusto Pires de Souza, Betânia Paiva Drumond, Gustavo Portela Ferreira, Breno de Mello Silva, Cintia Lopes de Brito Magalhães, Luciana Lara Santos, Jaqueline Maria Siqueira Ferreira, Luiz Cosme Cotta Malaquias, Luiz Felipe Leomil Coelho
Dengue is the most prevalent arthropod-borne viral illness in humans worldwide. Single-nucleotide polymorphisms (SNPs) in genes involved in the immune response, such as dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), IgG Fc receptor II-A (FcγRIIa), vitamin D receptor (VDR), and tumor necrosis factor alpha (TNF-α), were previously reported to be associated with susceptibility to dengue disease in different human populations. Therefore, due to the relevant association of host immune and genetic status with disease susceptibility/severity of dengue, this work aims to verify the frequency of anti-dengue virus antibodies and some dengue-associated risk SNPs in a population in Minas Gerais State, Southeast Brazil...
November 21, 2017: Immunogenetics
https://www.readbyqxmd.com/read/29161789/current-status-of-thyroid-fine-needle-aspiration-practice-in-thailand
#8
REVIEW
Somboon Keelawat, Samreung Rangdaeng, Supinda Koonmee, Tikamporn Jitpasutham, Andrey Bychkov
Thyroid carcinoma is one of the leading malignancies in Thailand increasingly prevalent in the female population. Fine-needle aspiration (FNA) cytology is a widely used diagnostic tool for evaluation of thyroid nodules and thyroid cancer. Thyroid FNA is a routine procedure universally performed in Thai hospitals by a variety of clinical specialists. Manual guidance is the first-line choice complemented by ultrasound assistance in selected cases. Despite national guidelines recommendations, the diagnostic criteria and terminology of the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) was slowly adopted in the local settings...
November 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29161746/exercise-performed-concomitantly-with-particulate-matter-exposure-inhibits-lung-injury
#9
Adriano Silva-Renno, Guilherme Crisitanini Baldivia, Manoel C Oliveira-Junior, Maysa Alves Rodrigues Brandao-Rangel, Elias El-Mafarjeh, Marisa Dolhnikoff, Thaís Mauad, Jôse Mára Britto, Paulo Hilário Nascimento Saldiva, Luis Vicente Franco Oliveira, Ana P Ligeiro-Oliveira, Gustavo Silveira Graudenz, Rodolfo Paula Vieira
Air pollution is a growing problem worldwide, inducing and exacerbating several diseases. Among the several components of air pollutants, particulate matter (PM), especially thick (10-2.5 µm; PM 10) and thin (≤2.5 µm; PM 2.5), are breathable particles that easily can be deposited within the lungs, resulting in pulmonary and systemic inflammation. Although physical activity is strongly recommended, its effects when practiced in polluted environments are questionable. Therefore, the present study evaluated the pulmonary and systemic response of concomitant treadmill training with PM 2...
November 21, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29161577/histological-characteristics-of-the-gonads-of-pig-fetuses-and-their-relationship-with-fetal-anatomical-measurements
#10
Thais Preisser Pontelo, José Rafael Miranda, Matheus Augusto Rodrigues Felix, Barbara Azevedo Pereira, William Eduardo da Silva, Gleide Fernandes Avelar, Flávia Cristina Martins Queiroz Mariano, Gregório Corrêa Guimarães, Márcio Gilberto Zangeronimo
The objective was to evaluate the histomorphometric characteristics of the testis and ovaries of pig fetuses at different gestational ages, as well as their correlation with some fetus measurements. Forty-four fetuses were separated for gender (male and female) and gestational age (50, 80 and 106days of gestation). After slaughter, fetuses had their body length, head and thoracic perimeters measured and their gonads submitted to histomorphometric analyses. The gonadal characteristics at different gestational ages were statistically compared, correlations with the fetal measurements were performed and equations to predict the gonadal characteristics from the fetal measurements were obtained...
November 11, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/29161053/long-term-effectiveness-of-omalizumab-treatment-in-thai-severe-asthmatic-patients-a-real-life-experience
#11
Theerasuk Kawamatawong, Orapan Poachanukoon, Chalermporn Boonsiri, Atik Saengasapaviriya, Atik Saengasapaviriya, Chanchai Sittipunt, Hiroshi Chantaphakul, Atik Saengasapaviriya, Kittipong Maneechotesuwan, Pintip Ngamchanyaporn, Kunchit Piyavechviratana, Praparn Yongjaiyut, Apichart Khanisap, Siwasak Juthong, Warangkana Rithirak, Prapaporn Pornsuriyasak, Chaicharn Pothirat, Watchara Boonsawat
BACKGROUND: To evaluate long-term effectiveness of omalizumab in 'real-life' setting of Thai asthmatic patients. METHODS: We conducted multi-center, observational study in severe asthma patients who received omalizumab in Thailand. Outcomes were asthma exacerbation (hospitalization and ER visit), asthma control test (ACT), and daily ICS dose. Data were evaluated at baseline, 16 Week, and 52 Week. RESULTS: A total of 78 patients received omalizumab treatment (average duration 16...
November 22, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/29160903/smoking-cessation-leads-to-changes-in-survivin-expression-in-oral-mucosa
#12
Celina Faig Lima, Erica Crastechini, Nathalia Curto Dos Santos, Ana Carolina Prado Ribeiro, Thais Bianca Brandão, Félix Cristiano Ferreira de Castro, Jaqueline Scholz Issa, Janete Dias Almeida
BACKGROUND: Survivin is an inhibitor protein of apoptosis and play a role in oral carcinogenesis mechanism. METHODS: This aim of this study was to evaluate the effect of smoking in survivin expression of oral mucosa of chronic smokers with and without oral squamous cell carcinoma (OSCC). The study was composed of three groups: Group 1 - 26 patients smoking more than 20 cigarettes/day/10 years without either history of oral malignant neoplasia or visible clinical signs in the examined site; Group 2 - 26 patients with OSCC; Group 3 - 22 patients surgically treated for OSCC for at least 1 month...
November 21, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29160858/hyperplanar-morphological-clustering-of-a-hippocampus-by-using-volumetric-computerized-tomography-in-early-alzheimer-s-disease
#13
Sarawut Suksuphew, Paramate Horkeaw
Background: On diagnosing Alzheimer's disease (AD), most existing imaging-based schemes have relied on analyzing the hippocampus and its peripheral structures. Recent studies have confirmed that volumetric variations are one of the primary indicators in differentiating symptomatic AD from healthy aging. In this study, we focused on deriving discriminative shape-based parameters that could effectively identify early AD from volumetric computerized tomography (VCT) delineation, which was previously almost intangible...
November 21, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29160520/spatial-risk-of-tuberculosis-mortality-and-social-vulnerability-in-northeast-brazil
#14
Thaís Zamboni Berra, Ana Angélica Rêgo de Queiroz, Mellina Yamamura, Luiz Henrique Arroyo, Maria Concebida da Cunha Garcia, Marcela Paschoal Popolin, Danielle Talita Dos Santos, Antonio Carlos Vieira Ramos, Luana Seles Alves, Inês Estevinho Fronteira, Francisco Chiaravalloti, Pedro Fredemir Palha, Ricardo Alexandre Arcêncio
INTRODUCTION: Tuberculosis (TB) is the most common infectious disease in the world. We aimed to analyze the spatial risk of tuberculosis mortality and to verify associations in high-risk areas with social vulnerability. METHODS: This was an ecological study. The scan statistic was used to detect areas at risk, and the Bivariate Moran Index was used to verify relationships between variables. RESULTS: High-risk areas of tuberculosis mortality were statistically significantly associated with domain 2 of the Social Vulnerability Index (I=0...
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29160453/conceptions-on-pharmaceutical-services-in-brazilian-primary-health-care
#15
Ediná Alves Costa, Patrícia Sodré Araújo, Thais Rodrigues Penaforte, Joslene Lacerda Barreto, Augusto Afonso Guerra, Francisco de Assis Acurcio, Ione Aquemi Guibu, Juliana Alvares, Karen Sarmento Costa, Margô Gomes de Oliveira Karnikowski, Orlando Mario Soeiro, Silvana Nair Leite
OBJECTIVE: To identify and discuss the conceptions of pharmaceutical services in Brazilian Primary Health Care, according to different subjects. METHODS: This study is part of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - Serviços, 2015 (PNAUM - National Survey on Access, Use and Promotion of Rational Use of Medicines - Services, 2015), which is composed of an information survey in a representative sample of cities, stratified according to Brazilian regions, and a subsample of primary health care services...
November 13, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29159904/growing-into-teen-fatherhood-a-grounded-theory-study
#16
C Uengwongsapat, K Kantaruksa, A Klunklin, N Sansiriphun
BACKGROUND: Becoming an adolescent father is a significant and critical life event. Expectant fathers are faced with a concurrent dual developmental crisis: being an adolescent and becoming a father. This transition has a tremendous impact on these adolescents, their families and society. The impact on these individuals and society does not, at this point, seem to be clearly understood. PURPOSE: To explore the process of Thai adolescents becoming first-time fathers with an unplanned pregnancy during their girlfriend's pregnancy...
November 21, 2017: International Nursing Review
https://www.readbyqxmd.com/read/29159481/effects-of-multi-component-mixtures-from-sewage-treatment-plant-effluent-on-common-carp-cyprinus-carpio-under-fully-realistic-condition
#17
Pham Thai Giang, Burkina Viktoriia, Sakalli Sidika, Schmidt-Posthaus Heike, Martin Krøyer Rasmussen, Randak Tomas, Grabic Roman, Grabicova Katerina, Fedorova Ganna, Koba Olga, Golovko Oksana, Turek Jan, Cerveny Daniel, Kolarova Jitka, Zlabek Vladimir
This study characterized changes in biomarker responses in common carp (Cyprinus carpio) upon exposure to effluent water discharged from a sewage treatment plant (STP) under real conditions. Fish were exposed to contamination in Cezarka pond, which receives all of its water input from the STP in the town of Vodnany, Czech Republic. Five sampling events were performed at day 0, 30, 90, 180, and 360 starting in April 2015. In total, 62 pharmaceutical and personal care products (PPCPs) were detected in the polar organic chemical integrative sampler...
November 20, 2017: Environmental Management
https://www.readbyqxmd.com/read/29159227/draft-genome-and-sequence-variant-data-of-the-oomycete-pythium-insidiosum-strain-pi45-from-the-phylogenetically-distinct-clade-iii
#18
Weerayuth Kittichotirat, Preecha Patumcharoenpol, Thidarat Rujirawat, Tassanee Lohnoo, Wanta Yingyong, Theerapong Krajaejun
Pythium insidiosum is a unique oomycete microorganism, capable of infecting humans and animals. The organism can be phylogenetically categorized into three distinct clades: Clade-I (strains from the Americas); Clade-II (strains from Asia and Australia), and Clade-III (strains from Thailand and the United States). Two draft genomes of the P. insidiosum Clade-I strain CDC-B5653 and Clade-II strain Pi-S are available in the public domain. The genome of P. insidiosum from the distinct Clade-III, which is distantly-related to the other two clades, is lacking...
December 2017: Data in Brief
https://www.readbyqxmd.com/read/29158524/mechanisms-underlying-the-antiproliferative-effects-of-a-series-of-quinoxaline-derived-chalcones
#19
Tânia R Mielcke, Thaís C Muradás, Eduardo C Filippi-Chiela, Maria Eduarda A Amaral, Luiza W Kist, Maurício R Bogo, Alessandra Mascarello, Patrícia D Neuenfeldt, Ricardo J Nunes, Maria M Campos
The present study aimed to characterize the effects of quinoxaline-derived chalcones, designed on the basis of the selective PI3Kγ inhibitor AS605240, in oral cancer cells. Three lead compounds, namely N9, N17 and N23, were selected from a series of 20 quinoxaline-derived chalcones, based on an initial screening using human and rat squamous cell carcinoma lineages, representing compounds with at least one methoxy radical at the A-ring. The selected chalcones, mainly N9 and N17, displayed marked antiproliferative effects, via apoptosis and autophagy induction, with an increase of sub-G1 population and Akt inhibition...
November 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29157317/entomopathogenic-bacteria-photorhabdus-luminescens-as-drug-source-against-leishmania-amazonensis
#20
Ana Maria Antonello, Thaís Sartori, Ana Paula Folmer Correa, Adriano Brandelli, Ralf Heermann, Luiz Carlos Rodrigues Júnior, Alessandra Peres, Pedro Roosevelt Torres Romão, Onilda Santos Da Silva
Leishmaniasis is a widely spread and zoonotic disease with serious problems as low effectiveness of drugs, emergence of parasite resistance and severe adverse reactions. In recent years, considerable attention has been given to secondary metabolites produced by Photorhabdus luminescens, an entomopathogenic bacterium. Here, we assessed the leishmanicidal activity of P. luminescens culture fluids. Initially, promastigotes of Leishmania amazonensis were incubated with cell free conditioned medium of P. luminescens and parasite survival was monitored...
November 21, 2017: Parasitology
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