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https://www.readbyqxmd.com/read/29035421/updated-guideline-may-improve-the-recognition-and-diagnosis-of-hypertension-in-children-and-adolescents-review-of-the-2017-aap-blood-pressure-clinical-practice-guideline
#1
REVIEW
Janis M Dionne
PURPOSE OF REVIEW: Hypertension in children and adolescents is under-recognized and under-diagnosed in clinical practice. The 2017 AAP Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents provides updated recommendations that may improve hypertension identification and management. RECENT FINDINGS: The AAP blood pressure guideline recommends annual screening for hypertension in children at preventive care visits and targeted routine screening in high-risk populations...
October 16, 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28990427/chew-on-this-not-all-first-finger-foods-are-created-equal
#2
Nicol Awadalla, Tammy Pham, Ruth Milanaik
The American Academy of Pediatrics (AAP) recommends when to start first finger foods (FFFs) and what types of foods to start with, but it is unclear whether products marketed as FFF comply with these recommendations. We evaluated FFF products for compliance with AAP recommendations and product safety using 41 adult product testers, who were asked to dissolve each product in their mouth. Product characteristics, comments pertaining to product safety, and time to dissolve each product were recorded. Only 2 products met all AAP criteria, and safety concerns were raised for an additional 2 products...
October 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28988296/pivotal-factors-for-successful-withdrawal-of-nonsteroidal-anti-inflammatory-drugs-in-rheumatoid-arthritis-patients-in-remission-or-with-low-disease-activity
#3
Dong Jin Go, Kichul Shin, Han Joo Baek, Seong Wook Kang, Young Mo Kang, Jae Bum Jun, Yun Jong Lee, Sung Hwan Park, Yeong Wook Song
The purpose of this study is to examine the patient-reported outcomes (PRO) after discontinuing nonsteroidal anti-inflammatory drugs (NSAIDs) and clinical factors associated with a favorable outcome in patients with rheumatoid arthritis (RA) in remission or with low-disease activity (LDA). A 16-week prospective open-label trial was conducted at eight rheumatology clinics in Korea. RA patients with 28-joint disease activity score based on erythrocyte sedimentation rate (DAS28-ESR) < 3.2 who were on NSAIDs for more than a month were enrolled, and NSAIDs were discontinued...
October 8, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28986090/urinary-tract-infection-in-children-diagnosis-treatment-imaging-comparison-of-current-guidelines
#4
REVIEW
M Okarska-Napierała, A Wasilewska, E Kuchar
BACKGROUND AND OBJECTIVE: Urinary tract infection (UTI) is a frequent disorder of childhood, yet the proper approach for a child with UTI is still a matter of controversy. The objective of this study was to critically compare current guidelines for the diagnosis and management of UTI in children, in light of new scientific data. METHODS: An analysis was performed of the guidelines from: American Academy of Pediatrics (AAP), National Institute for Health and Care Excellence (NICE), Italian Society of Pediatric Nephrology, Canadian Paediatric Society (CPS), Polish Society of Pediatric Nephrology, and European Association of Urology (EAU)/European Society for Pediatric Urology (ESPU)...
September 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28983658/newborn-screening-for-biliary-atresia-in-the-united-states
#5
Cat Goodhue, Michael Fenlon, Kasper S Wang
Despite advances in our understanding of the pathogenesis of biliary atresia (BA), BA remains the most common cause of end-stage liver disease in children and the leading indication for pediatric liver transplantation. Age at time of Kasai portoenterostomy (KPE), performed to provide bile drainage, strongly correlates with transplant-free survival, mostly due to progression of intrahepatic fibrosis to cirrhosis. Unfortunately, challenges remain in recognizing that a jaundiced infant may have BA. To better diagnose infants with BA at an earlier age, population-based screening programs in countries such as Taiwan, Japan, and China have utilized stool color cards...
October 5, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28975730/from-the-chair-of-the-aap-section-on-cardiology-cardiac-surgery
#6
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28971356/how-close-are-we-to-profiling-immunogenicity-risk-using-in-silico-algorithms-and-in-vitro-methods-an-industry-perspective
#7
Jochem Gokemeijer, Vibha Jawa, Shibani Mitra-Kaushik
In silico HLA-binding algorithms and in vitro T cell-based assays as predictive tools for human immunogenicity risk have made inroads in the biotherapeutic drug discovery and development process. Currently, these tools are being used only for candidate selection or characterization and not for making a go/no-go decision for further development. A clear limitation for a broader implementation is the lack of correlation between the predicted T cell epitope content/immune reactivity potential of a biotherapeutic and the subsequent ADA-related clinical immunogenicity outcome...
October 2, 2017: AAPS Journal
https://www.readbyqxmd.com/read/28967333/american-academy-of-periodontology-best-evidence-consensus-statement-on-selected-oral-applications-for-cone-beam-computed-tomography
#8
George A Mandelaris, E Todd Scheyer, Marianna Evans, David Kim, Bradley McAllister, Marc L Nevins, Hector F Rios, David Sarment
BACKGROUND: The American Academy of Periodontology (AAP) recently embarked on a Best Evidence Consensus (BEC) model of scientific inquiry to address questions of clinical importance in periodontology for which there is insufficient evidence to arrive at a definitive conclusion. This review addresses oral indications for use of cone-beam computed tomography (CBCT). METHODS: To develop the BEC, the AAP convened a panel of experts with knowledge of CBCT and substantial experience in applying CBCT to a broad range of clinical scenarios that involve critical structures in the oral cavity...
October 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28965276/fruit-juice-for-children-aap-recommendations-implications-for-india
#9
REVIEW
Umesh Kapil, Neha Sareen
No abstract text is available yet for this article.
September 30, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28958818/structural-characterization-of-a-new-water-soluble-polysaccharide-isolated-from-acanthophyllum-acerosum-roots-and-its-antioxidant-activity
#10
Kambiz Jahanbin
A new water-soluble polysaccharide named as AAPS-1, was extracted with warm water from the roots of Acanthophyllum acerosum and further purified by DEAE-cellulose A52 anion-exchange and Sephadex G-50 gel filtration chromatography. AAPS-1 was a neutral polysaccharide, with a molecular weight of 23.2kDa and a specific optical rotation of +181.3° (c 1.0, H2O), and comprised of Glucose, Galactose and Arabinose with a relative molar ratio of 1.6:5.1:1.0. Structure features of AAPS-1 were investigated by a combination of chemical and instrumental analysis, such as partial acid hydrolysis, methylation, periodate oxidation and Smith degradation, GC-MS, FTIR and NMR ((13)C and (1)H)...
September 25, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28956218/phase-behavior-of-ritonavir-amorphous-solid-dispersions-during-hydration-and-dissolution
#11
Hitesh S Purohit, Lynne S Taylor
PURPOSE: The aim of this research was to study the interplay of solid and solution state phase transformations during the dissolution of ritonavir (RTV) amorphous solid dispersions (ASDs). METHODS: RTV ASDs with polyvinylpyrrolidone (PVP), polyvinylpyrrolidone vinyl acetate (PVPVA) and hydroxypropyl methylcellulose acetate succinate (HPMCAS) were prepared at 10-50% drug loading by solvent evaporation. The miscibility of RTV ASDs was studied before and after exposure to 97% relative humidity (RH)...
September 27, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28952376/parental-knowledge-of-aap-juice-guidelines-is-associated-with-parent-and-children-s-consumption-of-juice-and-sugar-sweetened-beverages-in-an-underserved-population
#12
Christine SanGiovanni, Robert Fallar, Robert Green, Leora Mogilner
This study tested whether parental knowledge of the American Academy of Pediatrics' (AAP) recommendations on juice limits for children is associated with decreased consumption of juice and sugar-sweetened beverages (SSBs) among parents and children. Fifty-two parents with children 2 to 12 years old in a resident continuity clinic in East Harlem, New York, completed a survey asking about children's and parent's practice and quantitative consumption of juice and SSBs as well as parental knowledge of the AAP recommendations on juice limits...
March 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28947605/aap-publications-retired-and-reaffirmed
#13
(no author information available yet)
No abstract text is available yet for this article.
September 25, 2017: Pediatrics
https://www.readbyqxmd.com/read/28946159/palivizumab-the-effects-of-prophylactic-immunization-on-the-occurrence-of-infections-caused-by-the-respiratory-syncytial-virus
#14
Marjana Jerkovic Raguz, Jerko Brzica, Ivana Grgic
Aim The aim of this research is to analyze the characteristics of children immunized during immunization season, and their readmission to hospital due to infections of the respiratory tract in the period from 2008 to 2016. Method The retrospective cohort study included 101 children. The test group consists of infants who met the strict criteria for immunization. The national guidance was determined on the basis of earlier research and recommendations by the AAP. All the children who had been readmitted for hospitalization were quickly tested for RSV...
September 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28941917/national-trends-in-the-management-of-primary-vesicoureteral-reflux-in-children
#15
Michael Garcia-Roig, Curtis Tavers, Courtney E McCracken, Andrew J Kirsch
PURPOSE: In September 2011 the AAP (American Academy of Pediatrics) released updated guidelines for the evaluation of children 2 to 24 months old with a febrile urinary tract infection. We documented the impact of the guideline on diagnosis and surgical management of vesicoureteral reflux at U.S. children's hospitals. We hypothesized that voiding cystourethrogram studies and the vesicoureteral reflux treatment rate decreased concurrent with the national guideline release. MATERIALS AND METHODS: The Pediatric Health Information System was queried for children (younger than 18 years) with primary vesicoureteral reflux and their antireflux surgical history from January 2004 to June 2015...
September 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28939004/the-phase-3-cou-aa-302-study-of-abiraterone-acetate-plus-prednisone-in-men-with-chemotherapy-na%C3%A3-ve-metastatic-castration-resistant-prostate-cancer-stratified-analysis-based-on-pain-prostate-specific-antigen-and-gleason-score
#16
Kurt Miller, Joan Carles, Jürgen E Gschwend, Hendrik Van Poppel, Joris Diels, Sabine D Brookman-May
BACKGROUND: In the COU-AA-302 study (NCT00887198), abiraterone acetate plus prednisone (AAP) significantly improved outcomes in patients with metastatic castration-resistant prostate cancer (mCRPC) versus prednisone alone. Baseline clinical parameters predicting that treatment response could help inform clinical decisions were explored. OBJECTIVE: To identify patients who derive the greatest clinical benefit from AAP treatment. DESIGN, SETTING, AND PARTICIPANTS: A total of 1088 mCRPC patients treated with either AAP or prednisone in the first-line setting in COU-AA-302 were included in this post hoc analysis...
September 20, 2017: European Urology
https://www.readbyqxmd.com/read/28936817/-assessment-of-adolescent-attachment-styles-via-narrative-responses-to-the-thematic-stimulus
#17
Zeynep Tüzün, Gonca Soygüt
OBJECTIVE: The aim of this research is to develop a new protocol with a projective test and qualitative assessment approach for investigating mental representations effective for the formation of attachment styles and to examine its psychometric properties. METHOD: Thirty-three adolescents who admitted to the Division of Adolescent Medicine of Hacettepe University participated to the study. The Adolescent Attachment Protocol (AAP) and Relationship Styles Questionnaire (RSQ) were used...
2017: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/28933929/diagnostic-accuracy-of-two-food-insecurity-screeners-recommended-for-use-in-health-care-settings
#18
Jennifer A Makelarski, Emily Abramsohn, Jasmine H Benjamin, Senxi Du, Stacy Tessler Lindau
OBJECTIVES: To test the diagnostic accuracy of the American Academy of Pediatrics (AAP) recommended food insecurity screener. METHODS: We conducted prospective diagnostic accuracy studies between July and November 2016 in Chicago, Illinois. We recruited convenience samples of adults from adult and pediatric emergency departments (12-month recall study: n = 188; 30-day recall study: n = 154). A self-administered survey included the 6-item Household Food Security Screen (gold standard), the validated 2-item Hunger Vital Sign (HVS; often, sometimes, never response categories), and the 2-item AAP tool (yes-or-no response categories)...
November 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28933570/developing-pictorial-asthma-action-plans-to-promote-self-management-and-health-in-rural-youth-with-asthma-a-qualitative-study
#19
Christina L Duncan, Heather A Walker, Laurel Brabson, Desireé N Williford, Lisa Hynes, Mary Beth Hogan
OBJECTIVE: Asthma action plans (AAPs) provide asthma management instructions to families; however, AAPs typically are written at a 7th-9th grade reading level, making them less useful in lower literacy families. There is a need to develop simpler AAP formats and content to optimize their utility across all families, including those who are rural and may be at a risk for literacy concerns. Because using pictures can simplify and enhance health education, our study's aim was to develop a pictorial AAP through a series of focus groups with key stakeholders - youth with asthma, caregivers, and physicians...
September 21, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28924062/national-trends-in-pediatricians-practices-and-attitudes-about-breastfeeding-1995-to-2014
#20
Lori Feldman-Winter, Kinga Szucs, Aubri Milano, Elizabeth Gottschlich, Blake Sisk, Richard J Schanler
BACKGROUND AND OBJECTIVES: The American Academy of Pediatrics (AAP) has affirmed breastfeeding as the preferred method of infant feeding; however, there has been little systematic examination of how pediatricians' recommendations, affiliated hospitals' policies, counseling practices, and attitudes toward breastfeeding have shifted over the past 2 decades. These trends were examined from 1995 to 2014. METHODS: Data are from the Periodic Survey (PS) of Fellows, a nationally representative survey of AAP members...
October 2017: Pediatrics
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