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https://www.readbyqxmd.com/read/29159794/high-fat-high-sugar-diet-induced-subendothelial-matrix-stiffening-is-mitigated-by-exercise
#1
Julie C Kohn, Julian Azar, Francesca Seta, Cynthia A Reinhart-King
Consumption of a high-fat, high-sugar diet and sedentary lifestyle are correlated with bulk arterial stiffening. While measurements of bulk arterial stiffening are used to assess cardiovascular health clinically, they cannot account for changes to the tissue occurring on the cellular scale. The compliance of the subendothelial matrix in the intima mediates vascular permeability, an initiating step in atherosclerosis. High-fat, high-sugar diet consumption and a sedentary lifestyle both cause micro-scale subendothelial matrix stiffening, but the impact of these factors in concert remains unknown...
November 20, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29153315/what-are-the-keys-to-a-longer-happier-life-answers-from-five-decades-of-health-psychology-research
#2
Blair T Johnson, Rebecca L Acabchuk
RATIONALE: It has long been known that factors of the mind and of interpersonal relationships influence health, but it is only in the last 50 years that an independent scientific field of health psychology appeared, dedicated to understanding psychological and behavioral processes in health, illness, and healthcare. OBJECTIVE AND METHOD: This article (a) reviews important research that answers the question of how human beings can have longer, happier lives; and (b) highlights trends in health psychology featuring articles in Social Science & Medicine as well as other related literature...
November 4, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29142011/effect-of-distinct-lifestyle-interventions-on-mobilization-of-fat-storage-pools-the-central-mri-randomized-controlled-trial
#3
Yftach Gepner, Ilan Shelef, Dan Schwarzfuchs, Hila Zelicha, Lilac Tene, Anat Yaskolka Meir, Gal Tsaban, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Oded Komy, Arik Wolak, Yoash Chassidim, Rachel Golan, Hilla Avni-Hassid, Avital Bilitzky, Benjamin Sarusi, Eyal Goshen, Elad Shemesh, Yaakov Henkin, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Uta Ceglarek, Assaf Rudich, Meir J Stampfer, Iris Shai
Background -We aimed to assess whether distinct lifestyle strategies can differentially affect specific body adipose depots. Methods -We performed an eighteen-month randomized controlled trial among 278 sedentary adults with abdominal obesity (75%) or dyslipidemia in an isolated workplace with a monitored provided lunch. Participants were randomized to iso-caloric low-fat (LF) or Mediterranean/low-carbohydrate (MED/LC) diet+28g walnuts/day with/without added moderate physical activity (PA;80% aerobic; supervised/free gym membership)...
November 15, 2017: Circulation
https://www.readbyqxmd.com/read/29141966/nutritional-factors-affecting-adult-neurogenesis-and-cognitive-function
#4
REVIEW
Shibu M Poulose, Marshall G Miller, Tammy Scott, Barbara Shukitt-Hale
Adult neurogenesis, a complex process by which stem cells in the hippocampal brain region differentiate and proliferate into new neurons and other resident brain cells, is known to be affected by many intrinsic and extrinsic factors, including diet. Neurogenesis plays a critical role in neural plasticity, brain homeostasis, and maintenance in the central nervous system and is a crucial factor in preserving the cognitive function and repair of damaged brain cells affected by aging and brain disorders. Intrinsic factors such as aging, neuroinflammation, oxidative stress, and brain injury, as well as lifestyle factors such as high-fat and high-sugar diets and alcohol and opioid addiction, negatively affect adult neurogenesis...
November 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/29136476/effectiveness-of-a-school-based-program-focusing-on-diet-and-health-habits-taught-through-physical-exercise
#5
Ana Pablos, Vicente Nebot, Vicente Vañó-Vicent, Diego Ceca, Laura Elvira
The global rate of obesity in childhood is becoming an epidemic and many authors have established a significant association between childhood obesity and overweight in adulthood. It is therefore necessary to seek effective strategies to reduce these levels of obesity. The aim of this study was to evaluate the impact of the Healthy Habits Program (HHP). The participants were 158 children from the 5th and 6th grades (Intervention Group [IG] n=82, Control Group [CG] n=76). The HHP is a school-based physical activity program focusing on promoting a healthy lifestyle...
November 14, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29136159/associations-between-maternal-lifestyle-factors-and-neonatal-body-composition-in-the-screening-for-pregnancy-endpoints-cork-cohort-study
#6
Darren L Dahly, Xia Li, Hazel A Smith, Ali S Khashan, Deirdre M Murray, Mairead E Kiely, Jonathan O'B Hourihane, Fergus P McCarthy, Louise C Kenny, Patricia M Kearney
Background: Neonatal body composition likely mediates fetal influences on life long chronic disease risk. A better understanding of how maternal lifestyle is related to newborn body composition could thus inform intervention efforts. Methods: Using Cork participant data (n = 1754) from the Screening for Pregnancy Endpoints (SCOPE) cohort study [ECM5(10)05/02/08], we estimated how pre-pregnancy body size, gestational weight gain, exercise, alcohol, smoking and diet were related to neonatal fat and fat-free mass, as well as length and gestational age at birth, using quantile regression...
November 10, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29133322/factors-contributing-to-medicine-related-problems-in-adult-patients-with-diabetes-and-or-cardiovascular-diseases-in-saudi-arabia-a-qualitative-study
#7
Abdullah Mahdi Al Hamid, Maisoon Ghaleb, Hisham Aljadhey, Zoe Aslanpour
OBJECTIVES: To investigate the factors contributing to medicine-related problems (MRPs) among patients with cardiovascular diseases (CVDs) and/or diabetes in Saudi Arabia. DESIGN: Qualitative semistructured interviews were conducted. Interviews were audio recorded then transcribed into Microsoft Word. The transcribed interviews were then imported into the qualitative analysis software NVivo where thematic analysis was applied. Thematic synthesis was achieved by coding and developing subthemes/themes from the findings of the interviews...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29130068/diet-and-physical-activity-behaviors-in-primary-care-patients-with-recent-intentional-weight-loss
#8
Bethany Barone Gibbs, Dana Tudorascu, Cindy L Bryce, Diane Comer, Gary S Fischer, Rachel Hess, Kimberly A Huber, Kathleen M McTigue, Laurey R Simkin-Silverman, Molly B Conroy
Purpose: Lifestyle habits of primary care patients with recent, intentional weight loss are unclear and need to be better understood to aid in translational health promotion efforts. We aimed to characterize diet and exercise habits in primary care patients with recent, intentional weight loss, comparing those with greater (≥10%) vs. lesser (5 to <10%) weight loss. Methods: This was a cross-sectional analysis of baseline data from a randomized trial comparing weight loss maintenance interventions...
2017: Translational Journal of the American College of Sports Medicine
https://www.readbyqxmd.com/read/29128055/current-treatment-of-nonalcoholic-fatty-liver-disease-nonalcoholic-steatohepatitis
#9
REVIEW
Chun Kit Hung, Henry C Bodenheimer
Treatment of nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) is focused on patients with NASH because they are at highest risk for progressive liver disease. Current first-line treatment consists of lifestyle modifications. Patients should lose at least 7% to 10% of body weight via a combination of physical exercise and calorie restriction dieting. Surgical or endoscopic surgery for weight loss can be considered in obese patients, depending on degree of excess body weight and comorbidities...
February 2018: Clinics in Liver Disease
https://www.readbyqxmd.com/read/29127590/body-mass-index-diet-and-exercise-testing-possible-linkages-to-breast-cancer-risk-via-dna-methylation
#10
Arielle S Gillman, Casey K Gardiner, Claire E Koljack, Angela D Bryan
PURPOSE: To examine DNA methylation as a mechanism linking diet, physical activity, weight status, and breast cancer risk. METHODS: Insufficiently active women of varying weight status, without a history of cancer, completed a maximal exercise test, clinical measurement of height and weight, and a dietary intake measure. They also provided blood samples, which were analyzed to ascertain average methylation of candidate genes related to breast cancer (BRCA1, RUNX3, GALNT9, and PAX6) and inflammation (TLR4 and TLR6)...
November 10, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29122259/diet-and-lifestyle-intervention-on-chronic-moderate-to-severe-depression-and-anxiety-and-other-chronic-conditions
#11
Gary Null, Luanne Pennesi
This group study explored how an intervention of diet, lifestyle and behavior modification, including a plant-based diet, daily exercise and mindfulness techniques, would affect 500 adult men and women participants diagnosed with chronic moderate to severe depression and anxiety and other conditions during a 12 week period. An analysis of the health outcomes detailed in self-reported diary entries was carried out at the conclusion of the 12 week period. These reports noted improvements in depression, anxiety and all other conditions addressed by the study, with the majority of participants reporting substantial benefits...
November 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29120192/weight-stigma-and-health-the-mediating-role-of-coping-responses
#12
Mary S Himmelstein, Rebecca M Puhl, Diane M Quinn
OBJECTIVE: Considerable evidence has documented links between weight stigma and poor health, independent of weight. However, little research has assessed how individuals cope with weight stigma, and how stigma-specific coping responses contribute to health. The present study examined multiple stigma-specific coping responses as mediators of the relationship between experienced weight stigma and health. METHOD: A diverse national sample of 912 adults (53.9% female, Mage = 40...
November 9, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29113510/interrelationship-of-canonical-and-non-canonical-wnt-signalling-pathways-in-chronic-metabolic-diseases
#13
Ian Ackers, Ramiro Malgor
Chronic diseases account for approximately 45% of all deaths in developed countries and are particularly prevalent in countries with the most sophisticated and robust public health systems. Chronic metabolic diseases, specifically lifestyle-related diseases pertaining to diet and exercise, continue to be difficult to treat clinically. The most prevalent of these chronic metabolic diseases include obesity, diabetes, non-alcoholic fatty liver disease, chronic kidney disease and cardiovascular disease and will be the focus of this review...
November 1, 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/29108205/-investigation-and-analysis-of-the-knowledge-of-nonalcoholic-fatty-liver-disease-among-residents-in-hebei-province-china
#14
Q F Liang, Y D Wang, C Y Zhao
Objective: To investigate the knowledge of nonalcoholic fatty liver disease (NAFLD) among medical staff and general population in Hebei Province, China, understand the degree of awareness of NAFLD among residents, standardize the diagnosis and treatment of NAFLD, improve the correct awareness of NAFLD among general population, promote the establishment of a reasonable lifestyle, and scientifically and effectively control the incidence and mortality rates of NAFLD. Methods: The investigation was performed in 30 hospitals and neighboring schools and communities in Hebei Province, and a questionnaire survey on the knowledge of NAFLD was performed for 1 300 medical workers and 2 000 persons from the general population...
October 20, 2017: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/29103210/insulin-for-the-treatment-of-women-with-gestational-diabetes
#15
REVIEW
Julie Brown, Luke Grzeskowiak, Kathryn Williamson, Michelle R Downie, Caroline A Crowther
BACKGROUND: Gestational diabetes mellitus (GDM) is associated with short- and long-term complications for the mother and her infant. Women who are unable to maintain their blood glucose concentration within pre-specified treatment targets with diet and lifestyle interventions will require anti-diabetic pharmacological therapies. This review explores the safety and effectiveness of insulin compared with oral anti-diabetic pharmacological therapies, non-pharmacological interventions and insulin regimens...
November 5, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29099819/an-educational-strategy-that-promotes-healthy-habits-in-elderly-people-with-hypertension-in-a-municipality-of-colombia-a-participatory-action-research-study
#16
María Carolina López-Mateus, Erwin Hernando Hernández-Rincón, Camilo Alejandro Correal-Muñoz, Gina Paola Cadena-Buitrago, Ingrid Johanna Galvis-Díaz, Génesis Esmeralda Romero-Prieto
OBJECTIVE: To identify resources of the municipality of Sopó-Cundinamarca, Colombia, that are also opportunities to strengthen the development of an educational strategy that promotes healthy habits (healthy diet and exercise) as part of the comprehensive management of hypertension in the elderly. METHODS: A qualitative study of a participatory-action research initiative in the Community Day Center of Sopó in the second semester of 2015. It was developed in three stages: first, a community diagnosis showed the need to integrate the culture, traditions and resources of the municipality as inputs that allow the adherence of healthy styles by the elderly for the control of hypertension; in the second stage, a work plan was established based on actions provided by the community; and in the third stage, we reflected on the results...
October 30, 2017: Medwave
https://www.readbyqxmd.com/read/29098617/effects-of-exercise-on-arrhythmia-and-viceversa-lesson-from-the-greek-mythology
#17
Caterina Lambiase, Silvia Macerola, Giovanna Bosco, Elisa Messina, Pasquale Franciosa
Exercise represents an important lifestyle factor in all human ages when felt in harmony with other psycho-physical and environmental variables that affect individual life (e. g. quality of interest, affections, environment, diet and food). Consequently, in addition to the training level, the amount, intensity and modality of exercise (ana-/aerobic, isometric/isotonic), need to be personalized, considering the underlying diseases, which may benefit from it or worsening.Greek mythology gives us good examples of the exercise concept's evolution...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29098616/hypertension-and-exercise-training-evidence-from-clinical-studies
#18
Ivana C Moraes-Silva, Cristiano Teixeira Mostarda, Antonio Carlos Silva-Filho, Maria Claudia Irigoyen
Hypertension is a worldwide prevalent disease, mostly manifested as its primary ethiology, characterized by a chronic, multifactorial, asymptomatic, and usually incurable state. It is estimated that more than one billion of the world population is hypertensive. Also, hypertension is the main cause of the two most frequent causes of death worldwide: myocardial infarction and stroke. Due to the necessity of the cardiovascular system to manage chronically increased levels of blood pressure, hypertension causes severe alterations in multiple organs, as the heart, vessels, kidneys, eyes and brain, thus increasing the risk of health complications...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29080342/cross-talk-between-bile-acids-and-gastro-intestinal-and-thermogenic-clues-from-bariatric-surgery
#19
Gabriella Garruti, Agostino Di Ciaula, Helen H Wang, David Q-H Wang, Piero Portincasa
Obesity is rapidly increasing and has reached epidemic features worldwide. It´s linked to insulin resistance, systemic low-grade inflammation and common pathogenic pathways with a number of comorbidities (including cancer), leading to high mortality rates. Besides change of lifestyles (diet and physical exercise) and pharmacological therapy, bariatric surgery is able to rapidly improve several metabolic and morphologic features associated with excessive fat storage, and currently represents an in vivo model to study the pathogenic mechanisms underlying obesity and obesity-related complications...
October 28, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/29075629/carbohydrate-restriction-with-high-intensity-interval-training-an-optimal-combination-for-treating-metabolic-diseases
#20
Monique E Francois, Jenna B Gillen, Jonathan P Little
Lifestyle interventions incorporating both diet and exercise strategies remain cornerstone therapies for treating metabolic disease. Carbohydrate-restriction and high-intensity interval training (HIIT) have independently been shown to improve cardiovascular and metabolic health. Carbohydrate-restriction reduces postprandial hyperglycemia, thereby limiting potential deleterious metabolic and cardiovascular consequences of excessive glucose excursions. Additionally, carbohydrate-restriction has been shown to improve body composition and blood lipids...
2017: Frontiers in Nutrition
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