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https://www.readbyqxmd.com/read/29785077/mediterranean-diet-and-nonalcoholic-fatty-liver-disease
#1
REVIEW
Caterina Anania, Francesco Massimo Perla, Francesca Olivero, Lucia Pacifico, Claudio Chiesa
Nonalcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver disease, and is characterized by a wide spectrum of fat-liver disorders that can result in severe liver disease and cirrhosis. Inflammation and oxidative stress are the major risk factors involved in the pathogenesis of NAFLD. Currently, there is no consensus concerning the pharmacological treatment of NAFLD. However, lifestyle interventions based on exercise and a balanced diet for quality and quantity, are considered the cornerstone of NAFLD management...
May 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29781380/finally-a-regimen-to-extend-human-life-expectancy
#2
James Larrick, Andrew R Mendelsohn
The US has the most expensive healthcare system worldwide. Yet measures of healthspan and life expectancy are well below the major industrialized nations. With the US population aged 65 and older projected to double by mid-century a healthcare crisis is looming. Within this context huge interest and investment has emerged in technologies and drugs to address aging with an expected benefit to healthspan. The thesis being that such basic interventions will reduce morbidity caused by many chronic diseases where biological age itself is the major risk factor...
May 21, 2018: Rejuvenation Research
https://www.readbyqxmd.com/read/29781379/innovative-curriculum-integrating-the-bio-behavioral-and-social-science-principles-across-the-lifestages-in-basic-science-years
#3
Anuradha Lele Mookerjee, Bradford D Fischer, Susan Cavanaugh, Vijay Rajput
Behavioral and social science integration in clinical practice improves health outcomes across the life stages. The medical school curriculum requires an integration of the behavioral and social science principles in early medical education. We developed and delivered a four-week course entitled "LifeStages" to the first year medical students. The learning objectives of the bio-behavioral and social science principles along with the cultural, economic, political, and ethical parameters were integrated across the lifespan in the curriculum matrix...
May 20, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29774489/the-role-of-lifestyle-in-male-infertility-diet-physical-activity-and-body-habitus
#4
REVIEW
Russell P Hayden, Ryan Flannigan, Peter N Schlegel
PURPOSE OF REVIEW: Increasing attention to primary and secondary prevention of male infertility through modifiable lifestyle factors has gained traction amongst both patients and infertility specialists. In this review, the available evidence of modifiable lifestyle choices, specifically diet, physical activity, and body habitus, are evaluated. RECENT FINDINGS: Studies examining diet, exercise/physical activity, and body habitus are characterized by conflicting conclusions, difficult confounders, and imperfect end points to judge male reproductive potential...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29768343/potential-common-factors-associated-with-predisposition-to-common-cold-in-middle-aged-and-elderly-japanese-a-community-based-cross-sectional-study
#5
Michi Shibata, Taizo Iwane, Ryoko Higuchi, Kaname Suwa, Kei Nakajima
People worldwide frequently catch a common cold, which occasionally develops into secondary severe conditions such as pneumonia. However, it is unclear whether predisposition to the common cold is associated with the individual's characteristics including age, body weight, lifestyles, diets, and intestinal functions, besides exposure to a responsible pathogen. We addressed this issue epidemiologically considering many relevant clinical factors.We reviewed data from a cross-sectional study consisting of 39,524 apparently healthy Japanese aged 40 to 79 years (26,975 men and 12,549 women) who underwent a checkup in 2007...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29766791/immunometabolic-changes-in-hepatocytes-arising-from-obesity-and-the-practice-of-physical-exercise
#6
Paula Alves Monteiro, Wagner Prado, Thiago Ricardo Dos Santos Tenório, Luciane Magri Tomaz, David H St-Pierre, Fabio Santos Lira
Over the recent years, a particular interest was shown towards understanding the roles of excessive hepatic fat accumulation and the development of obesity-related diseases. While hepatic triacylglycerol accumulation seems to be a response to the systemic increase of insulin release, fatty acid metabolites contribute to the progression of non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH). It is widely accepted that NAFLD is a polygenic and multifactorial disease under the influence of critical behavioral factors such as overeating and sedentary lifestyles...
May 14, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29757226/inflammation-not-cholesterol-is-a-cause-of-chronic-disease
#7
REVIEW
Alexandros Tsoupras, Ronan Lordan, Ioannis Zabetakis
Since the Seven Countries Study, dietary cholesterol and the levels of serum cholesterol in relation to the development of chronic diseases have been somewhat demonised. However, the principles of the Mediterranean diet and relevant data linked to the examples of people living in the five blue zones demonstrate that the key to longevity and the prevention of chronic disease development is not the reduction of dietary or serum cholesterol but the control of systemic inflammation. In this review, we present all the relevant data that supports the view that it is inflammation induced by several factors, such as platelet-activating factor (PAF), that leads to the onset of cardiovascular diseases (CVD) rather than serum cholesterol...
May 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29756977/effects-of-red-wine-grape-juice-and-resveratrol-consumption-on-bone-parameters-of-wistar-rats-submitted-to-high-fat-diet-and-physical-training
#8
Letícia Monteiro da Fonseca Cardoso, Nina Da Matta Alvarez Pimenta, Raiza Da Silva Ferreira Fiochi, Bruna Ferreira Mota Mota, Juliana Arruda de Souza Monnerat, Cristiane Correia Teixeira, Renata Beatriz Da Rocha Ramalho, Isabelle Waleska Maldronato, Manuela Dolisnky, Gilson Teles Boaventura, Vilma Blondet, Sergio Girão Barroso, Carlos Alberto Soares da Costa, Gabrielle De Souza Rocha
INTRODUCTION: intake of diets with high saturated fat may produce deleterious effects on bone mineralization. Lifestyle changes help reduce the bone loss observed in osteoporosis. Resveratrol, present in grape juice and red wine, has osteogenic and osteoinductive effects, being potentially beneficial for bone health. OBJECTIVE: to evaluate the effects of red grape juice, red wine and resveratrol consumption on bone parameters in Wistar rats submitted to a high-fat diet and physical training...
October 27, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29755757/need-to-improve-awareness-and-treatment-compliance-in-high-risk-patients-for-diabetic-complications-in-nepal
#9
Raju P Sapkota, Tirthalal Upadhyaya, Govind Gurung, Mike Parker, Rajiv Raman, Shahina Pardhan
Objective/introduction: It is known that knowledge, awareness, and practice influence diabetic control. We compared factors pertaining to healthy lifestyle (exercising, avoiding smoking), self-help (attending appointments, following treatment regimens), and diabetic awareness in high-risk patients for diabetic complications, specifically, those on insulin versus non-insulin treatment, and also those with a longer diabetic duration (≥5 years) versus a shorter duration. Methods: 200 consecutive patients with type 2 diabetes (52...
2018: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/29745325/life-style-and-peptic-ulcer-disease
#10
Berrak C Yegen
The risk of developing peptic ulcer disease (PUD) was shown to be associated with genetic inheritance, life-style and social status of the patients. Unhealthy lifestyle habits and failure in coping with stress have been closely associated with the occurrence of PUD. In contrary, limiting the use of analgesic drugs and glucocorticoids, controlling environmental and socioeconomic factors that predispose to H. Pylori infection, having a balanced diet, exercising regularly, coping successfully with stress, avoiding smoking, limiting alcohol intake and getting sufficient night sleep are essential in prevention and healing of PUD...
May 9, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29742035/what-do-patients-talk-about-a-qualitative-analysis-of-online-chat-sessions-with-healthcare-specialists-during-a-virtual-cardiac-rehabilitation-program
#11
Joanna Mendell, Joanna Bates, Davina Banner-Lukaris, Dan Horvat, Bindy Kang, Joel Singer, Andrew Ignaszewski, Scott A Lear
INTRODUCTION: Cardiac rehabilitation programs (CRPs) are effective at reducing cardiovascular disease (CVD) risk, yet attendance in these programs remains low due to geographic constraints. In a previously conducted randomized trial we demonstrated that a virtual CRP (vCRP) delivered over the Internet reduced risk for CVD. The current investigation has reviewed the online chat sessions between participants and healthcare providers (HCP) to describe the content of discussions during the vCRP intervention...
May 9, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29741425/the-effects-of-structured-exercise-or-lifestyle-behavior-interventions-on-long-term-physical-activity-level-and-health-outcomes-in-individuals-with-type-2-diabetes-a-systematic-review-meta-analysis-and-meta-regression
#12
Marjan Mosalman Haghighi, Yorgi Mavros, Maria A Fiatarone Singh
BACKGROUND: Systematically evaluate the effects of structured exercise and behavioral intervention (physical activity [PA] alone/PA + diet) on long-term PA in type 2 diabetes. METHODS: Systematic search of 11 databases (inception to March, 2017). Randomized controlled trials investigating structured exercise/behavioral interventions in type 2 diabetes reporting PA outcomes ≥6 months were selected. RESULTS: Among 107,797 citations retrieved, 23 randomized controlled trials (including 18 behavioral programs and 5 structured exercise) met inclusion criteria (n = 9640, 43...
May 9, 2018: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/29735796/non-alcoholic-fatty-liver-disease-in-children-and-adolescents-lifestyle-change-a-systematic-review-and-meta-analysis
#13
Melina Utz-Melere, Cristina Targa-Ferreira, Bernardo Lessa-Horta, Matias Epifanio, Marialena Mouzaki, Angelo A Mattos
INTRODUCTION AND AIM: This manuscript seeks to analyze the impact of lifestyle changes on body mass index (BMI), aminotransferases and steatosis in children and adolescents with nonalcoholic fatty liver disease (NAFLD). MATERIALS AND METHODS: A review of PubMed, BIREME, Scopus, EMBASE, Medline and Web of Science databases 2015 was performed seeking studies addressing the impact of lifestyle interventions on children and/or adolescents with NAFLD. Inclusion were manuscripts written in Portuguese, English and Spanish, as well as age less than 18 years...
April 9, 2018: Annals of Hepatology
https://www.readbyqxmd.com/read/29735380/people-s-beliefs-and-expectations-about-how-cognitive-skills-change-with-age-evidence-from-a-u-k-wide-aging-survey
#14
Eleftheria Vaportzis, Alan J Gow
OBJECTIVE: We conducted a U.K.-wide survey to collect information on people's beliefs, fears, perceptions, and attitudes to cognitive aging. METHODS: This community-based aging survey included 3,146 adults aged 40 years and over. RESULTS: Respondents believed memory might be the earliest cognitive skill to decline (mean: 59.4 years), followed by speed of thinking (mean: 64.9). Those in their 40s were more pessimistic, because they estimated cognitive changes would start up to 15 years earlier than respondents aged over 70...
April 4, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29731703/metabolic-syndrome-and-neuroprotection
#15
REVIEW
Melisa Etchegoyen, Mariana H Nobile, Francisco Baez, Barbara Posesorski, Julian González, Néstor Lago, José Milei, Matilde Otero-Losada
Introduction: Over the years the prevalence of metabolic syndrome (MetS) has drastically increased in developing countries as a major byproduct of industrialization. Many factors, such as the consumption of high-calorie diets and a sedentary lifestyle, bolster the spread of this disorder. Undoubtedly, the massive and still increasing incidence of MetS places this epidemic as an important public health issue. Hereon we revisit another outlook of MetS beyond its classical association with cardiovascular disease (CVD) and Diabetes Mellitus Type 2 (DM2), for MetS also poses a risk factor for the nervous tissue and threatens neuronal function...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29728820/obesity-diet-and-lifestyle-in-9-year-old-children-with-parentally-reported-chronic-diseases-findings-from-the-growing-up-in-ireland-longitudinal-child-cohort-study
#16
Michael P Fitzgerald, Kerrie Hennigan, Clodagh S O'Gorman, Laura McCarron
BACKGROUND: The incidence and prevalence of childhood chronic disease is increasing worldwide. Obesity, poor diet and lifestyle may be more prevalent in children with a chronic disease than in their healthier contemporaries. The Growing Up in Ireland (GUI) study is a nationally representative cohort study of children living in the Republic of Ireland. The study has collected information from 8568 9-year-old Irish children on their experiences within their families, childcare settings, schools and communities, and how these impact on all aspects of children's development...
May 5, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29723176/the-dunedin-dementia-risk-awareness-project-a-convenience-sample-of-general-practitioners
#17
Yoram Barak, Charlene Rapsey, Dana Fridman, Kate Scott
AIMS: Recent recommendations of US and UK governmental and academic agencies suggest that up to 35% of dementia cases are preventable. We aimed to appraise general practitioners' (GPs) awareness of risk and protective factors associated with dementia and their intentions to act within the context of the Health Beliefs Model. METHODS: We canvassed degree of dementia awareness, using the modified Lifestyle for Brain Health (LIBRA) scale among a convenience sample of local GPs...
May 4, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29719871/a-prospective-metagenomic-and-metabolomic-analysis-of-the-impact-of-exercise-and-or-whey-protein-supplementation-on-the-gut-microbiome-of-sedentary-adults
#18
Owen Cronin, Wiley Barton, Peter Skuse, Nicholas C Penney, Isabel Garcia-Perez, Eileen F Murphy, Trevor Woods, Helena Nugent, Aine Fanning, Silvia Melgar, Eanna C Falvey, Elaine Holmes, Paul D Cotter, Orla O'Sullivan, Michael G Molloy, Fergus Shanahan
Many components of modern living exert influence on the resident intestinal microbiota of humans with resultant impact on host health. For example, exercise-associated changes in the diversity, composition, and functional profiles of microbial populations in the gut have been described in cross-sectional studies of habitual athletes. However, this relationship is also affected by changes in diet, such as changes in dietary and supplementary protein consumption, that coincide with exercise. To determine whether increasing physical activity and/or increased protein intake modulates gut microbial composition and function, we prospectively challenged healthy but sedentary adults with a short-term exercise regime, with and without concurrent daily whey protein consumption...
May 2018: MSystems
https://www.readbyqxmd.com/read/29718795/dietary-flavanols-a-review-of-select-effects-on-vascular-function-blood-pressure-and-exercise-performance
#19
Yousef A Al-Dashti, Roberta R Holt, Charles L Stebbins, Carl L Keen, Robert M Hackman
An individual's diet affects numerous physiological functions and can play an important role in reducing the risk of cardiovascular disease. Epidemiological and clinical studies suggest that dietary flavanols can be an important modulator of vascular risk. Diets and plant extracts rich in flavanols have been reported to lower blood pressure, especially in prehypertensive and hypertensive individuals. Flavanols may act in part through signaling pathways that affect vascular function, nitric oxide availability, and the release of endothelial-derived relaxing and constricting factors...
May 2, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29704911/vegans-report-less-bothersome-vasomotor-and-physical-menopausal-symptoms-than-omnivores
#20
Bonnie Beezhold, Cynthia Radnitz, Robert E McGrath, Arielle Feldman
OBJECTIVES: Lifestyle modifications that may reduce menopausal symptoms have generated much interest. The vegetarian diet has been associated with a lower risk of chronic disease as well as a more healthy hormonal milieu. Our objective in this cross-sectional study was to survey peri- and postmenopausal women to investigate menopausal symptoms and dietary pattern. STUDY DESIGN: Survey distribution in 2015-2016 was aimed at female vegans, vegetarians, and omnivores between the ages of 45 and 80 years, who were active on senior and vegetarian social networking websites and at vegan restaurants and events...
June 2018: Maturitas
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