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https://www.readbyqxmd.com/read/29650121/prediction-of-abnormal-myocardial-relaxation-from-signal-processed-surface-ecg
#1
Partho P Sengupta, Hemant Kulkarni, Jagat Narula
BACKGROUND: Myocardial relaxation is impaired in almost all cases with left ventricular diastolic dysfunction (LVDD) and is a strong predictor of cardiovascular and all-cause mortality. OBJECTIVES: This study investigated the feasibility of signal-processed surface electrocardiography (spECG) as a diagnostic tool for predicting the presence of abnormal cardiac muscle relaxation. METHODS: A total of 188 outpatients referred for coronary computed tomography (CT) angiography underwent an echocardiogram for assessment of LVDD...
April 17, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29643926/the-evaluation-of-left-ventricular-diastolic-dysfunction-in-patients-with-non-hemorrhagic-stroke-and-atrial-fibrillation
#2
REVIEW
Mahdi Najafi-Dalui, Hasan Shemirani, Reyhaneh Zavar, Ali Eghbal
BACKGROUND: Atrial fibrillation (AF) is the most common tachyarrhythmia and an important risk factor for thromboembolic stroke. CHA2DS2-VASc score was introduced for assessment of embolic events and as criteria for starting anticoagulants. This study was performed to evaluate the left ventricular diastolic dysfunction (LVDD) in patients with non-hemorrhagic stroke and AF. METHODS: This cross-sectional study consisted of 76 consecutive patients with suspected non-hemorrhagic stroke referred to the Cardiology Department of Alzahra and Ayatollah Kashani hospitals in Isfahan, Iran, during 2015-2016...
November 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29618307/safety-and-efficacy-of-adenovirus-carrying-hepatocyte-growth-factor-gene-by-percutaneous-endocardial-injection-for-treating-post-infarct-heart-failure-a-phase-iia-clinical-trial
#3
Haoyu Meng, Bo Chen, Zhengxian Tao, Zhihui Xu, Liansheng Wang, Ju Weizhu, Yongyong Hong, Xiang Liu, Hua Wang, Lisheng Wang, Zuze Wu, Zhijian Yan
OBJECTIVE: Our previous phase I clinical trial has confirmed the safety of adenovirus carrying hepatocyte growth factor gene (Ad-HGF) by intracoronary administration for treating severe coronary artery disease. This study was performed to evaluated the safety and efficacy of Ad-HGF by percutaneous endocardial injection for treating post-infarct heart failure. METHODS: A total of 30 patients (15 in the experimental group and 15 in the control group) with post-infarct heart failure who were not indicated to revascularization and had received the optimal standardized medication therapy were included in the study...
April 4, 2018: Current Gene Therapy
https://www.readbyqxmd.com/read/29609877/impact-of-catheter-ablation-of-atrial-fibrillation-on-long-term-clinical-outcomes-in-patients-with-heart-failure
#4
Sadamitsu Ichijo, Shinsuke Miyazaki, Shigeki Kusa, Hiroaki Nakamura, Hitoshi Hachiya, Takatsugu Kajiyama, Yoshito Iesaka
BACKGROUND: Heart failure (HF) promotes atrial fibrillation (AF) and AF worsens HF. This study aimed to investigate the long-term clinical outcomes after AF ablation in patients with HF. METHODS AND RESULTS: A total of 106 consecutive HF patients, including 51 (48.1%) with a reduced left ventricular ejection fraction (LVEF) (HFrEF) and 55 (51.9%) with a preserved LVEF (HFpEF), underwent AF ablation. All patients underwent successful pulmonary vein antrum isolation, and substrate modification was added in 38 (35...
March 30, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29560600/prevalence-of-cardiovascular-dysfunction-and-its-association-with-outcome-in-patients-with-acute-pancreatitis
#5
Raghavendra Prasada, Narendra Dhaka, Ajay Bahl, Thakur Deen Yadav, Rakesh Kochhar
BACKGROUND: Organ failure (OF) is the most important predictor of outcome in severe acute pancreatitis (SAP). Cardiovascular failure (CVSF) occurs in a variable proportion of patients with SAP. We aimed to study myocardial dysfunction in acute pancreatitis (AP) and its impact on the outcome. METHODS: In this prospective study between January 2011 and July 2012, consecutive eligible patients of AP were enrolled. Myocardial function was assessed by measuring CK-MB (creatine phosphokinase isoenzyme) and echocardiography at admission...
March 21, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29506691/impaired-left-atrial-systolic-function-and-inter-atrial-dyssynchrony-may-contribute-to-symptoms-of-heart-failure-with-preserved-left-ventricular-ejection-fraction-a-comprehensive-assessment-by-echocardiography
#6
Shuang Liu, Zhengyu Guan, Xianfeng Zheng, Pingping Meng, Yonghuai Wang, Yang Li, Yan Zhang, Jun Yang, Dalin Jia, Chunyan Ma
AIMS: To assess LA diastolic and systolic function and atrial dyssynchrony in patients with heart failure with preserved ejection fraction (HFpEF) and to examine whether LA dysfunction and dyssynchrony account for the patients' symptoms of HFpEF. METHODS: Fifty-five patients with HFpEF, 31 asymptomatic patients with left ventricular diastolic dysfunction (LVDD) and 33 healthy individuals were enrolled in the study. The LA active ejection fraction (LAAEF) was calculated...
April 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29501544/the-impact-of-left-ventricular-diastolic-dysfunction-on-clinical-outcomes-after-transcatheter-aortic-valve-replacement
#7
Masahiko Asami, Jonas Lanz, Stefan Stortecky, Lorenz Räber, Anna Franzone, Dik Heg, Lukas Hunziker, Eva Roost, George Cm Siontis, Marco Valgimigli, Stephan Windecker, Thomas Pilgrim
OBJECTIVES: This study sought to determine the impact of left ventricular (LV) diastolic dysfunction (LVDD) on clinical outcomes in patients undergoing transcatheter aortic valve replacement (TAVR). BACKGROUND: LV hypertrophy in response to afterload increase promotes the development of LVDD and represents an early stage in the progression to valvular heart failure. METHODS: In a consecutive cohort of 777 aortic stenosis patients undergoing TAVR, LVDD was categorized according to the latest guidelines...
February 24, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29491324/endogenous-adenosine-may-be-related-to-left-ventricular-dysfunction-dilation-and-wall-thinning-in-patients-with-heart-disease
#8
Yujiro Kinomura, Toshiki Tanaka, Takuma Aoyama, Masanori Hatasa, Shingo Minatoguchi, Masamitsu Iwasa, Yoshihisa Yamada, Takahide Nawa, Hiromitsu Kanamori, Masanori Kawasaki, Yukihiro Esaka, Bunji Uno, Kazuhiko Nishigaki, Shinya Minatoguchi
BACKGROUND: The role of endogenous adenosine in cardiac patients is still unclear, so we investigated the relationship between the plasma adenosine concentration and left ventricular (LV) function, LV dilation and LV wall thinning in cardiac patients.Methods and Results:In 97 cardiac patients, with angina pectoris, old myocardial infarction, dilated or hypertrophic cardiomyopathy, and valvular heart disease, plasma adenosine concentrations were measured using the LC-MS/MS system, and the LV function, LV end-diastolic dimension (LVDd), LV posterior wall thickness (LVPWth), and interventricular septum thickness (IVSth) were assessed by echocardiography...
February 28, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29483384/-astragalus-membranaceus-improving-asymptomatic-left-ventricular-diastolic-dysfunction-in-postmenopausal-hypertensive-women-with-metabolic-syndrome-a-prospective-open-labeled-randomized-controlled-trial
#9
Ning-Yin Li, Heng Yu, Xiu-Li Li, Qiong-Ying Wang, Xiao-Wei Zhang, Rui-Xin Ma, Yang Zhao, Han Xu, Wei Liang, Feng Bai, Jing Yu
Background: Postmenopausal women with metabolic syndrome (MetS) have increased cardiovascular morbidity and left ventricular diastolic dysfunction (LVDD). The various protective effects of astragalus membranaceus (AM) have been described in previous studies. Therefore, this study aimed to evaluate the effects of different doses of AM on diastolic function in postmenopausal hypertensive women with MetS. Methods: This was a prospective, randomized controlled study...
March 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29460490/evaluation-of-sex-differences-in-the-relationship-between-diastolic-dysfunction-and-thromboembolism-using-propensity-score-analysis
#10
Mi-Na Kim, Jae-Min Shim, Jong-Il Choi, Seong-Mi Park, Young Hoon Kim, Wan Joo Shim
BACKGROUND: Female sex is a risk factor for thromboembolism (TE) in atrial fibrillation (AF); however, the underlying mechanisms are unclear. We postulated that left ventricular (LV) diastolic dysfunction (LVDD) could be associated with increased thromboembolic risk in women. METHODS: From a retrospective cohort, 158 patients (female : male = 79:79) with nonvalvular AF were propensity score-matched for age, presence of diabetes, hypertension, coronary artery disease, congestive heart failure, embolic history, AF type, and AF duration...
February 20, 2018: Echocardiography
https://www.readbyqxmd.com/read/29446818/heart-involvement-in-systemic-sclerosis
#11
Ihsen Zairi, Lilia Baili, Khadija Mzoughi, Manel Dridi, Zouhaier Jnifene, Fatma Boussema
INTRODUCTION: Primary and secondary heart involvement in systemic sclerosis are important mortality predictors. Aim of this study was to investigate by standard echocardiography associated to pulsed-tissue Doppler imaging, six-minute walk test (6MWT) and BNP level cardiac manifestation in 30 patients with ScS and to establish a strategy to detect and to evaluate this complication. METHODS: This was a cross-sectional study conducted over a period of 16 months: a total of 30 consecutive patients with ScS diagnosed as proposed by the American college of Rheumatology and the European League Against Rheumatism 2013 and who were hospitalized in Internal Medicine department of Habib Thameur hospital underwent cardiac assessment...
March 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29425549/low-relative-muscle-mass-and-left-ventricular-diastolic-dysfunction-in-middle-aged-adults
#12
Byung-Joon Ko, Yoosoo Chang, Jeong Gyu Kang, Jimin Kim, Hyun-Suk Jung, Kyung Eun Yun, Chan-Won Kim, Hocheol Shin, Seungho Ryu
OBJECTIVES: The association between low skeletal muscle mass and left ventricular diastolic dysfunction (LVDD), a predictor of future heart failure, is largely unexplored. We investigated the relationship between relative muscle mass and LVDD. METHODS: We conducted a cross-sectional study in 67,106 Koreans who underwent an echocardiography as part of a comprehensive health examination between January 2012 and December 2014. Skeletal muscle mass index (SMI) [SMI (%)=total skeletal muscle mass (kg)/body weight (kg)×100] was estimated using a bioelectrical impedance analyzer...
March 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29417020/prevalence-of-left-ventricular-dysfunction-in-rheumatoid-arthritis
#13
A S Renjith, Vishal Marwaha, N Aggarwal, Varghese Koshy, V K Singal, K V S Hari Kumar
Background: Rheumatoid arthritis (RA) is a polyarticular disorder with many extra-articular features. Cardiovascular disorders, including heart failure (HF), are the leading causes of mortality in RA patients. We studied the prevalence of left ventricular dysfunction (LVD) in patients with RA. Materials and Methods: In this cross-sectional study, we evaluated 100 consecutive patients with RA (aged >18 years and duration >1 year) for the presence of LVD. We excluded patients with known cardiac and systemic disorders that may contribute to LVD...
July 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29398513/determinants-of-left-ventricular-diastolic-dysfunction-in-hypertensive-patients
#14
R Nazário Leão, P Marques da Silva, R Marques Pocinho, M Alves, D Virella, R Palma Dos Reis
INTRODUCTION: The progression of hypertensive heart disease leads to the left ventricular diastolic dysfunction (LVDD), which is associated with increased cardiovascular morbidity and mortality. The purpose of this analysis is to explore the determinants for LVDD in patients with hypertension. METHODS: This is a secondary analysis of data of Impedance Cardiography in the Evaluation of Left Ventricular Diastolic Dysfunction in Patients with Arterial Hypertension (IMPEDDANS) Study...
February 2, 2018: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/29389744/vascular-aging-and-preclinical-target-organ-damage-in-community-dwelling-elderly-the-northern-shanghai-study
#15
Hongwei Ji, Jiadela Teliewubai, Yuyan Lu, Jing Xiong, Shikai Yu, Chen Chi, Jue Li, Jacques Blacher, Yi Zhang, Yawei Xu
OBJECTIVES: Vascular aging represents a mediating step between risk factors and cardiovascular events, and preclinical target organ damage (TOD) integrates the cumulative effect of cardiovascular risk factors. This study is aimed at the relationships between vascular aging and TOD. METHODS: Two thousand and ninety-eight participants (45.52% men, aged 71.3 ± 6.1 years) were recruited from June 2014 to June 2017 from the communities in the northern Shanghai area...
January 31, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29333094/left-ventricular-diastolic-and-systolic-dyssynchrony-and-dysfunction-in-heart-failure-with-preserved-ejection-fraction-and-a-narrow-qrs-complex
#16
Shuang Liu, Zhengyu Guan, Xuanyi Jin, Pingping Meng, Yonghuai Wang, Xianfeng Zheng, Dalin Jia, Chunyan Ma, Jun Yang
Aims: Mechanical dyssynchrony has been reported in heart failure with preserved ejection fraction (HFpEF), with a majority of patients having a narrow QRS complex; however, whether any benefit is observed with restoration of dyssynchrony remains unclear. We sought to assess left ventricular (LV) dyssynchrony and function in HFpEF and elucidate the underlying mechanisms that may account for HFpEF. Methods: Seventy-eighty patients with a narrow QRS complex including 47 with HFpEF, 31 with heart failure with reduced ejection fraction (HFrEF) patients, and 29 with asymptomatic left ventricular diastolic dysfunction (LVDD) were recruited...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29297194/red-cell-distribution-width-and-its-relationship-with-global-longitudinal-strain-in-patients-with-heart-failure-with-reduced-ejection-fraction-a-study-using-two-dimensional-speckle-tracking-echocardiography
#17
Elif Eroglu, Alev Kilicgedik, Gokhan Kahveci, Ruken Bengi Bakal, Cevat Kirma
BACKGROUND: Red cell distribution width (RDW) is a measurement of size variability of the red blood cells and has been shown to be a powerful predictor of prognosis in heart failure (HF). Recently, global longitudinal strain (GLS) emerged as a more accurate marker of left ventricular (LV) systolic function. AIM: We aimed to assess the relationship between RDW and standard echocardiographic parameters and LV global strain measured by two-dimensional (2D) speckle tracking echocardiography in patients with HF with reduced EF (HFrEF)...
2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29288156/left-ventricular-torsion-shear-angle-volume-approach-for-noninvasive-evaluation-of-diastolic-dysfunction-in-preserved-ejection-fraction
#18
Oleg F Sharifov, Chun G Schiros, Inmaculada Aban, Gilbert J Perry, Louis J Dell'italia, Steven G Lloyd, Thomas S Denney, Himanshu Gupta
BACKGROUND: Accurate noninvasive diagnostic tools for evaluating left ventricular (LV) diastolic dysfunction (LVDD) are limited in preserved LV ejection fraction. We previously proposed the relationship of normalized rate of change in LV torsion shear angle (φ') to corresponding rate of change in LV volume (V') during early diastole (represented as -dφ'/dV') as a measure of LV diastolic function. We prospectively evaluated diagnostic accuracy of -dφ'/dV' in respect to invasive LV parameters...
December 29, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29276899/-left-ventricular-diastolic-dysfunction-in-endovascular-treatment-of-atrial-fibrillation-in-patients-with-preserved-ejection-fraction
#19
I G Nikitin, G E Gendlin, A M Baymukanov, I A Khamnagadaev, S A Termosesov, I L Iljich
AIM: To study prevalence of left ventricular diastolic dysfunction (LVDD) and to evaluate the effect of pulmonary vein catheter isolation on left ventricular (LV) diastolic function in patients with paroxysmal and persistent forms of atrial fibrillation (AF). MATERIALS AND METHODS: 109 patients with paroxysmal (n=90; 82.6 %) and persistent (n=19; 17.4 %) AF were evaluated after 109 pulmonary vein catheter isolations. The patients were divided into two groups based on the operation efficacy...
2017: Kardiologiia
https://www.readbyqxmd.com/read/29260535/-application-of-echocardiography-to-support-transapical-transcatheter-aortic-valve-implantation-in-patients-with-aortic-regurgitation
#20
Ming-Dan Deng, Xin Wei, Hong Tang, Yu-Yan Cai, Gu-Yue Liu, Da Zhu, Ying-Qiang Guo
OBJECTIVE: To explore the role of echocardiography in pre-procedural,peri-procedural and post-procedural stages of transapical transcatheter aortic valve implantation (TAVI) in patients with aortic regurgitation (AR). METHODS: 31 patients with pure/dominant AR at a high risk on surgery were enrolled in this study. The degree of their aortic regurgitation was evaluated before TAVI,as well as the related diameters of aortic root and the left ventricular systolic function measured by transthoracic echocardiography (TTE)...
November 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
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