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https://www.readbyqxmd.com/read/28980280/renin-angiotensin-system-inhibition-is-associated-with-reduced-risk-of-left-atrial-appendage-thrombosis-formation-in-patients-with-atrial-fibrillation
#1
Ya Suo, Yue Zhang, Yuanyuan Wang, Meng Yuan, Sayuri Kariyawasam, Gary Tse, Tong Liu, Huaying Fu, Guangping Li
BACKGROUND: Inhibition of the renin-angiotensin axis can reduce the likelihood of atrial fibrillation (AF). However, the effects of angiotensin-converting-enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) on thrombogenicity in AF remain incompletely elucidated. Thisretrospective case-control study was conducted to evaluate whether the use of ACEI or ARB could reduce the incidence of left atrial appendage thrombus (LAAT) and spontaneous echocardiographic contrast (SEC) in patients with AF...
October 5, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28977386/lower-limit-of-normality-and-clinical-relevance-of-left-ventricular-early-diastolic-strain-rate-for-the-detection-of-left-ventricular-diastolic-dysfunction
#2
Daniel A Morris, Masaaki Takeuchi, Satoshi Nakatani, Yutaka Otsuji, Evgeny Belyavskiy, Radhakrishnan Aravind Kumar, Athanasios Frydas, Martin Kropf, Robin Kraft, Esteban Marquez, Engin Osmanoglou, Maximilian Krisper, Clemens Köhncke, Leif-Hendrik Boldt, Wilhelm Haverkamp, Carsten Tschöpe, Frank Edelmann, Burkert Pieske, Elisabeth Pieske-Kraigher
Aims: The aim of the present study was to determine the lower limit of normality and the clinical relevance of left ventricular (LV) early diastolic strain rate (LVSRe) for the detection of LV diastolic dysfunction (LVDD). Methods and results: Using 2D speckle-tracking echocardiography, we analysed 377 healthy subjects and 475 patients with risk for LVDD with preserved LV ejection fraction (LVEF). The normal range of LVSRe analysing the healthy subjects was 1.56 ± 0...
August 3, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28911024/ambulatory-pulse-pressure-predicts-the-development-of-left-ventricular-diastolic-dysfunction-in-over-20-years-of-follow-up
#3
Tero J W Pääkkö, Reko J Renko, Juha S Perkiömäki, Y Antero Kesäniemi, Antti S Ylitalo, Jarmo A Lumme, Heikki V Huikuri, Heikki Ruskoaho, Olli Vuolteenaho, Olavi H Ukkola
BACKGROUND: Ambulatory blood pressure (ABP) has been shown to have an association with left ventricular diastolic dysfunction (LVDD) in cross-sectional assessments. We evaluated the association between ABP measurement (ABPM) and the development of LVDD during over 20 years of follow up in 414 middle-aged subjects from OPERA cohort. METHODS: ABPM, clinical, and anthropometric measurements were performed in baseline. Echocardiographic measurements were performed at baseline and during follow-up and E/E' ≥15 was considered indicating significant LVDD...
October 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28890308/left-ventricular-mass-geometry-and-function-in-diabetic-patients-affected-by-coronary-artery-disease
#4
Maria Maiello, Annapaola Zito, Santa Carbonara, Marco Matteo Ciccone, Pasquale Palmiero
INTRODUCTION: Coronary artery disease (CAD) is quite common among diabetic patients, our study goal is to detect the prevalence of left ventricular (LV) adverse changes in geometry, mass and diastolic function on diabetic, but not hypertensive patients, with coronary artery disease(CAD) and LV ejection fraction(LVEF)>45%, actually unknown, because of current guidelines that do not include echocardiographic assessment for follow up of diabetic patients. PATIENTS AND METHODS: 665 consecutive diabetic patients (443 females, mean age 66±9years), performed a complete echocardiographic assessment according to current ASE echo-guidelines: diastolic dysfunction (DD), eccentric hypertrophy (EH), concentric hypertrophy (CH) and concentric remodeling (CR) of LV were reported...
October 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28871334/role-of-percutaneous-veno-arterial-extracorporeal-membrane-oxygenation-as-bridge-to-left-ventricular-assist-device
#5
Koichi Toda, Tomoyuki Fujita, Osamu Seguchi, Masanobu Yanase, Takeshi Nakatani
Percutaneous veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides emergency circulatory support for cardiogenic shock patients and is used as a bridge to a left ventricular assist device (LVAD). The purpose of this study was to determine risk factors for LVAD implantation in patients who required percutaneous VA-ECMO as a bridge to long-term LVAD. We retrospectively investigated 32 consecutive LVAD patients who required percutaneous VA-ECMO as a bridge to long-term LVAD. Twenty-nine patients (91%) were intubated, and their serum creatinine and total bilirubin levels before LVAD implantation were 2...
September 4, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/28810550/2d-sti-combined-with-gated-99-tc-m-mibi-mpi-for-the-diagnosis-of-myocardial-ischemia-in-hypercholesterolemia-patients
#6
Yi Song, Rui-Fang Zhang, Yu Liu
This study aimed to investigate the reliability of ultrasound two-dimensional speckle tracking imaging (2D-STI) for the evaluation of myocardial ischemia in familial hypercholesterolemia (FH) patients. We recruited 28 patients clinically diagnosed with homozygous familial hypercholesterolemia (HoFH) and subjected them to 2D-STI, gated transthoracic Doppler echocardiography (TTDE), and (99)Tc(m)-methoxyisobutylisonitrile myocardial perfusion imaging ((99)Tc(m)-MIBI MPI). The sensitivity, specificity and diagnostic accordance rate of TTDE and 2D-STI for myocardial ischemia in HoFH patients were compared with the (99)Tc(m)-MIBI scores...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28796407/effects-of-gene-knockdown-of-cnp-on-ventricular-remodeling-after-myocardial-ischemia-reperfusion-injury-through-nprb-cgmp-signaling-pathway-in-rats
#7
Lian-He Wu, Qi Zhang, Shen Zhang, Lu-Yu Meng, Yan-Chi Wang, Cun-Jian Sheng
This study aimed to explore effects of CNP on ventricular remodeling following myocardial ischemia-reperfusion (I/R) injury through the NPRB/cGMP signaling pathway. Rat cardiomyocyteswere assigned into: control, I/R, I/R + CNP, and I/R+ 8-Br-cGMP groups. ELISA, qRT-PCR and western blotting were used to detect cGMP content and expression, respectively. After model establishment of I/R rats, normal control, CNP(-/-) control, I/R, and CNP(-/-) groups were set. Indexes of heart were detected using echocardiography and hemodynamics...
August 10, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28766046/relationship-between-left-ventricular-diastolic-dysfunction-and-very-late-recurrences-after-multiple-procedures-for-atrial-fibrillation-ablation
#8
Naoaki Onishi, Kazuaki Kaitani, Masashi Amano, Sari Imamura, Jiro Sakamoto, Yodo Tamaki, Soichiro Enomoto, Makoto Miyake, Toshihiro Tamura, Hirokazu Kondo, Chisato Izumi, Yoshihisa Nakagawa
Although very late recurrences (VLRs) (first recurrence >12 months after the last catheter ablation) of atrial fibrillation (AF) after multiple catheter ablation procedures are rare, it remains a critical issue. The risk factors for VLRs remain largely unclear. From December 2011 to April 2014, 253 patients underwent an initial catheter ablation. Of the 253 patients, 21 had AF recurrences within 1 year after the last catheter ablation. The study was conducted in the remaining 232 patients. Left ventricular diastolic dysfunction (LVDD) was assessed by echocardiography using composite categories with tissue Doppler imaging and left atrial volume measurements, i...
August 1, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28652715/association-of-arteriosclerosis-and-or-atherosclerosis-with-hypertensive-target-organ-damage-in-the-community-dwelling-elderly-chinese-the-northern-shanghai-study
#9
Ximin Fan, Mengyun Zhu, Chen Chi, Shikai Yu, Jing Xiong, Yuyan Lu, Bin Bai, Yawei Xu, Yi Zhang
OBJECTIVE: Vascular abnormality includes two forms, arteriosclerosis (ARS) and atherosclerosis (ATS), which coexist in patients with cardiovascular (CV) diseases. However, whether their combination may lead to a worsening status in those patients remains unclear. We therefore aimed to investigate the association of ARS and/or ATS with hypertensive target organ damage (TOD). METHODS: From June 2014 to August 2015, a total of 1,599 community-dwelling elderly subjects (aged >65 years) from northern Shanghai were recruited...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28638827/cardiovascular-autonomic-neuropathy-is-an-independent-risk-factor-for-left-ventricular-diastolic-dysfunction-in-patients-with-type-2-diabetes
#10
Jiewen Jin, Weimin Wang, Liangying Zhu, Tianwei Gu, Qing Niu, Ping Li, Yan Bi, Dalong Zhu
AIM: This study aimed to evaluate the association between cardiovascular autonomic neuropathy (CAN) and left ventricular diastolic dysfunction (LVDD) in type 2 diabetes patients. METHODS: 315 type 2 diabetes patients from inpatients of Drum Tower Hospital were included and classified into no CAN (NCAN), possible CAN (PCAN), and definite CAN (DCAN) based on cardiovascular autonomic reflex tests. The left ventricular diastolic function was assessed by tissue Doppler imaging echocardiography...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28625379/reliability-of-updated-left-ventricular-diastolic-function-recommendations-in-predicting-elevated-left-ventricular-filling-pressure-and-prognosis
#11
MULTICENTER STUDY
Kimi Sato, Andrew D M Grant, Kazuaki Negishi, Paul C Cremer, Tomoko Negishi, Arnav Kumar, Patrick Collier, Samir R Kapadia, Richard A Grimm, Milind Y Desai, Brian P Griffin, Zoran B Popović
An updated 2016 echocardiographic algorithm for diagnosing left ventricular (LV) diastolic dysfunction (DD) was recently proposed. We aimed to assess the reliability of the 2016 echocardiographic LVDD grading algorithm in predicting elevated LV filling pressure and clinical outcomes compared to the 2009 version. METHODS: We retrospectively identified 460 consecutive patients without atrial fibrillation or significant mitral valve disease who underwent transthoracic echocardiography within 24 hours of elective heart catheterization...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28569260/association-of-left-ventricular-structural-and-functional-abnormalities-with-aortic-and-brachial-blood-pressure-variability-in-hypertensive-patients-the-safar-study
#12
C Chi, S-K Yu, R Auckle, A A Argyris, E Nasothimiou, C Tountas, E Aissopou, J Blacher, M E Safar, P P Sfikakis, Y Zhang, A D Protogerou
Both brachial blood pressure (BP) level and its variability (BPV) significantly associate with left ventricular (LV) structure and function. Recent studies indicate that aortic BP is superior to brachial BP in the association with LV abnormalities. However, it remains unknown whether aortic BPV better associate with LV structural and functional abnormalities. We therefore aimed to investigate and compare aortic versus brachial BPV, in terms of the identification of LV abnormalities. Two hundred and three participants who underwent echocardiography were included in this study...
October 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28541599/improvement-of-left-ventricular-diastolic-function-and-left-heart-morphology-in-young-women-with-morbid-obesity-six-months-after-bariatric-surgery
#13
Katarzyna Kurnicka, Justyna Domienik-Karłowicz, Barbara Lichodziejewska, Maksymilian Bielecki, Marta Kozłowska, Sylwia Goliszek, Olga Dzikowska-Diduch, Wojciech Lisik, Maciej Kosieradzki, Piotr Pruszczyk
BACKGROUND: Obesity contributes to left ventricular diastolic dysfunction (LVDD) and may lead to diastolic heart failure. Weight loss (WL) after bariatric surgery (BS) may influence LV morphology and function. Using echocardiography, this study assessed the effect of WL on LV diastolic function (LVDF) and LV and left atrium (LA) morphology 6 months after BS in young women with morbid obesity. METHODS: Echocardiography was performed in 60 women with BMI ≥ 40kg/m², aged 37...
May 25, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28528875/comparison-of-central-and-peripheral-hemodynamics-in-association-with-left-ventricular-diastolic-dysfunction-in-the-community-based-elderly-chinese
#14
Jing Xiong, Xuejing Yu, Shikai Yu, Bin Bai, Henry Xu, Hongwei Ji, Jiadela Teliewubai, Kai Wang, Chen Chi, Yuyan Lu, Yiwu Zhou, Ximin Fan, Jue Li, Yi Zhang, Yawei Xu
The aim of the study was to investigate the association of left ventricular diastolic dysfunction (LVDD) with central and peripheral hemodynamics. A total of 1599 community-based senior residents (aged ≥ 65 years) in northern Shanghai, China, were recruited as of August 2015. Echocardiography was performed for each participant using the MyLab30 Gold CV system. According to the recommendations from the American Society of Echocardiography, the ratio of E (peak early diastolic transmitral flow velocity) to E' (early diastolic lateral mitral annulus velocity) was assessed for the evaluation of LVDD...
April 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28515821/left-ventricular-velocity-of-propagation-a-useful-non-invasive-measurement-when-assessing-hemodynamic-alterations-in-pulmonary-arterial-hypertension
#15
Dagmar F Hernandez-Suarez, Denada Palm, Francisco Lopez-Menendez, Marcel Mesa Pabon, Angel Lopez-Candales
BACKGROUND: Left ventricular (LV) velocity of propagation (Vp) has been shown to be inversely related to the LV relaxation time constant. We sought to examine Vp from a group of chronic pulmonary hypertension (cPH) patients and compare these values to Vp obtained in normal individuals and patients with known LV diastolic dysfunction (LVDD). METHODS: Echo-Doppler data and Vp measurements were retrospectively collected from all patients. The studied population was divided into four groups...
April 2017: Cardiology Research
https://www.readbyqxmd.com/read/28506387/effects-of-atorvastatin-treatment-on-left-ventricular-diastolic-function-in-peritoneal-dialysis-patients-the-alevent-clinical-trial
#16
Cho-Kai Wu, Chih-Fan Yeh, Jiun-Yang Chiang, Ting-Tse Lin, Yi-Fan Wu, Chih-Kang Chiang, Tze-Wah Kao, Kuan-Yu Hung, Jenq-Wen Huang
BACKGROUND: Left ventricular diastolic dysfunction (LVDD) is common among patients undergoing peritoneal dialysis (PD). Increased levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein, predict the development of LVDD. OBJECTIVES: We hypothesized that PD patients with elevated high-sensitivity C-reactive protein levels might benefit from statin treatment for LVDD and designed a randomized clinical trial to prove the hypothesis. METHODS: We screened 213 PD patients and randomly assigned 32 men and women with low-density lipoprotein cholesterol levels <130 mg/dL, high-sensitivity C-reactive protein levels of ≥1...
May 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28479168/relation-of-the-number-of-parity-to-left-ventricular-diastolic-function-in-pregnancy
#17
Muhammed Keskin, Şahin Avşar, Mert İlker Hayıroğlu, Taha Keskin, Edibe Betül Börklü, Adnan Kaya, Ahmet Okan Uzun, Burcu Akyol, Tolga Sinan Güvenç, Ömer Kozan
Left ventricular diastolic dysfunction (LVDD) has been relatively less studied than other cardiac changes during pregnancy. Previous studies revealed a mild diastolic deterioration during pregnancy. However, these studies did not evaluate the long-term effect of parity on left ventricular diastolic function. A comprehensive study evaluating the long-term effect of parity on diastolic function is required. A total of 710 women with various number of parity were evaluated through echocardiography to reveal the status of diastolic function...
July 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28460004/4d-flow-cardiac-magnetic-resonance-derived-vorticity-is-sensitive-marker-of-left-ventricular-diastolic-dysfunction-in-patients-with-mild-to-moderate-chronic-obstructive-pulmonary-disease
#18
Michal Schäfer, Stephen Humphries, Kurt R Stenmark, Vitaly O Kheyfets, J Kern Buckner, Kendall S Hunter, Brett E Fenster
Aims: To investigate the possibility that vorticity assessed by four-dimensional flow cardiac magnetic resonance (4D-Flow CMR) in the left ventricle of patients with mild-to-moderate chronic obstructive pulmonary disease (COPD) is a potential marker of early LV diastolic dysfunction (LVDD) and more sensitive than standard echocardiography, and whether changes in vorticity are associated with quantitative computed tomography (CT) and clinical markers of COPD, and right ventricular (RV) echocardiographic markers indicative of ventricular interdependency...
April 27, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28430594/the-prognostic-significance-of-preoperative-left-ventricular-diastolic-dysfunction-and-left-atrial-enlargement-on-acute-coronary-syndrome-in-kidney-transplantation
#19
Jin Ho Hwang, Jun-Bean Park, Yong-Jin Kim, Jung Nam An, Jaeseok Yang, Curie Ahn, In Mok Jung, Chun Soo Lim, Yon Su Kim, Young Hoon Kim, Jung Pyo Lee
Echocardiography is commonly performed as a screening test to evaluate perioperative risks before kidney transplantation. However, only limited data are available on echocardiographic parameters of left ventricular diastolic dysfunction (LVDD) and left atrial enlargement (LAE) on acute coronary syndrome and mortality in kidney transplant recipients. We reviewed 2779 adult recipients who underwent pretransplant echocardiography from 1997 to 2012. We divided the patients into two and four groups by two categories: LVDD grades 0-1 vs...
April 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28417009/revised-definition-of-predicted-left-ventricular-mass-using-ambulatory-blood-pressure-in-healthy-korean-adults
#20
Bae Keun Kim, Enshi Xu, Bo Youl Choi, Yonggu Lee, Soon Gil Kim, Yukio Yamori, Jinho Shin
BACKGROUND: Left ventricular hypertrophy is influenced by both hemodynamic and non-hemodynamic factors. Ambulatory blood pressure is correlated with left ventricular hypertrophy. We established the influences of hemodynamic and non-hemodynamic factors, including ambulatory blood pressure, on variation in left ventricular mass in healthy Korean adults. METHOD: We included 172 subjects (male = 71, female = 101), with normal body mass index and blood pressure, in an analysis of data from the Yangpyung and Yeoju cohort studies and a tertiary cardiovascular center...
2017: Clinical Hypertension
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