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José Luis Fernández-Alemán, Laura López-González, Ofelia González-Sequeros, Chrisina Jayne, Juan José López-Jiménez, Ambrosio Toval
OBJECTIVE: This paper presents an empirical study of a formative mobile-based assessment approach that can be used to provide students with intelligent diagnostic feedback to test its educational effectiveness. METHOD: An audience response system called SIDRA was integrated with a neural network-based data analysis to generate diagnostic feedback for guided learning. A total of 200 medical students enrolled in a General and Descriptive Anatomy of the Locomotor System course were taught using two different methods...
October 2016: International Journal of Medical Informatics
Mary Rudner
Everyday listening may be experienced as effortful, especially by individuals with hearing loss. This may be due to internal factors, such as cognitive load, and external factors, such as noise. Even when speech is audible, internal and external factors may combine to reduce cognitive spare capacity, or the ability to engage in cognitive processing of spoken information. A better understanding of cognitive spare capacity and how it can be optimally allocated may guide new approaches to rehabilitation and ultimately improve outcomes...
July 2016: Ear and Hearing
Kerstin Hoedlmoser, Juergen Birklbauer, Manuel Schabus, Patrick Eibenberger, Sandra Rigler, Erich Mueller
Diurnal sleep effects on consolidation of a complex, ecological valid gross motor adaptation task were examined using a bicycle with an inverse steering device. We tested 24 male subjects aged between 20 and 29 years using a between-subjects design. Participants were trained to adapt to the inverse steering bicycle during 45 min. Performance was tested before (TEST1) and after (TEST2) training, as well as after a 2 h retention interval (TEST3). During retention, participants either slept or remained awake. To assess gross motor performance, subjects had to ride the inverse steering bicycle 3 × 30 m straight-line and 3 × 30 m through a slalom...
February 2015: Journal of Sleep Research
Min-Kyoung Shin, Hong-Tae Park, Seung Won Shin, Myunghwan Jung, Young Bin Im, Hyun-Eui Park, Yong-Il Cho, Han Sang Yoo
Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic debilitating disease affecting ruminants worldwide. In the present study, we aimed to determine the major gene networks and pathways underlying the immune response to MAP infection using whole-blood cells, as well as provide the potential transcriptional markers for identifying the status of MAP infection. We analyzed the transcriptional profiles of whole-blood cells of cattle identified and grouped according to the presence of MAP-specific antibodies and the MAP shed by them...
February 2015: Journal of Microbiology and Biotechnology
Tina B Lonsdorf, Jan Haaker, Raffael Kalisch
Human context conditioning studies have focused on acquisition and extinction. Subsequent long-term changes in fear behaviors not only depend on associative learning processes during those phases but also on memory consolidation processes and the later ability to retrieve and express fear and extinction memories. Clinical theories explain relapse after successful exposure-based treatment with return of fear memories and remission with stable extinction memory expression. We probed contextual fear and extinction memories 1 week (Day8) after conditioning (Day1) and subsequent extinction (Day2) by presenting conditioned contexts before (Test1) and after (Test2) a reinstatement manipulation...
December 2014: Social Cognitive and Affective Neuroscience
Melanie Mitros, Kelley Pettee Gabriel, Barbara Ainsworth, Chong Lee, Stephen Herrmann, Kathy Campbell, Pamela Swan
Cardiorespiratory fitness is an independent predictor of cardiovascular events in women; however, maximal oxygen consumption (VO(2max)) protocols are not always feasible. The Evaluation of Physical Activity Measures in Middle-Aged Women Study was a 6-week study designed to evaluate six physical activity (PA) measures in women, aged 45-65 years. We investigated the Ebbeling submaximal treadmill (EbbTM) protocol's ability to reflect an active lifestyle in 66 women [median (IQR) age, 51.0 (48.0, 56.5) years]...
January 2011: European Journal of Applied Physiology
Maria Bartoletti, Alessia Colantoni, Valentina De Luca, Margherita Gaiardi
The GABA(B) agonists block the rewarding properties of opiates. However, the role of GABA(B) receptors in the discriminative properties of these drugs has received little attention. In this line, the present study was performed to investigate the effects of acute (Experiment 1) and chronic (Experiment 2) pretreatment with baclofen on the discriminative stimulus effects of morphine. Rats were trained to discriminate morphine (5mg/kgi.p.) from saline under a two-lever fixed-ratio schedule of food reinforcement...
December 2010: Pharmacology, Biochemistry, and Behavior
Roger Gomes Tavares Mello, Liliam Fernandes de Oliveira, Jurandir Nadal
This work aims at testing the influence of peripheral and central fatigue, after maximal oxygen uptake test (Test1) and prolonged (Test2) cycle ergometer exercises, respectively, on sway density curve (SDC) parameters of postural control. Sixteen healthy male subjects were submitted to stabilometric tests, before and after the exercises. The Test1 was started at 12.5W, with 12.5W/min increments and 50rpm cadence until exhaustion. From the respiratory gas exchange signals, the first ventilatory threshold was obtained by the v-slope method...
June 2010: Gait & Posture
Joepe J Kaandorp, Manon J N L Benders, Carin M A Rademaker, Helen L Torrance, Martijn A Oudijk, Timo R de Haan, Kitty W M Bloemenkamp, Monique Rijken, Maria G van Pampus, Arie F Bos, Martina M Porath, Sidarto Bambang Oetomo, Christine Willekes, A W Danilo Gavilanes, Maurice G A J Wouters, Ruurd M van Elburg, Anjoke J M Huisjes, Saskia C M J E R Bakker, Claudia A van Meir, Jeannette von Lindern, Janine Boon, Inge P de Boer, Robbert Jp Rijnders, Corrie J W F M Jacobs, Cuno S P M Uiterwaal, Ben Willem J Mol, Gerard H A Visser, Frank van Bel, Jan B Derks
BACKGROUND: Hypoxic-ischaemic encephalopathy is associated with development of cerebral palsy and cognitive disability later in life and is therefore one of the fundamental problems in perinatal medicine. The xanthine-oxidase inhibitor allopurinol reduces the formation of free radicals, thereby limiting the amount of hypoxia-reperfusion damage. In case of suspected intra-uterine hypoxia, both animal and human studies suggest that maternal administration of allopurinol immediately prior to delivery reduces hypoxic-ischaemic encephalopathy...
2010: BMC Pregnancy and Childbirth
Q Wu, G-T Liu, L-R Wang, Y-F Wu, X-L Wang
The aim of the present study is to explore an effective model of HIV/AIDS health education for a rural Chinese population. Students in two middle schools were given HIV/AIDS health education. The education in Tiechang town was carried out in the form of delivering multimedia lectures, video tapes and brochures, while in Daping town brochures were distributed to students. After receiving health education, each student extended the health education to three peasants who were their relatives or neighbours. After the education was provided, the test scores of AIDS knowledge increased significantly in the students of Tiechang town (0...
February 2010: International Journal of STD & AIDS
Ruth Dickstein, Michal Kafri
OBJECTIVES: To examine the effects of unilateral and bilateral application of low-dose high-frequency transcutaneous electrical stimulation (TENS) on EMG activity of the finger flexor muscles and on grip force in the right upper extremity. METHODS: Twelve healthy volunteers received unilateral, bilateral, and placebo (zero intensity) TENS stimulation to the finger flexor muscles in three separate sessions. TENS was delivered for 15 min at 100 Hz, with the amplitude adjusted to the sensory threshold...
2008: Somatosensory & Motor Research
Jarek Mäestu, Jaak Jürimäe, Ivo Valter, Toivo Jürimäe
The aim of this study was to investigate responses of ghrelin, leptin, and adiponectin to a weight reduction period of 10 weeks in male subjects with high lean body mass and low body fat values. Fourteen male bodybuilders (7 competitors: 28.3 +/- 10.3 years, 175.3 +/- 5.4 cm, 82.2 +/- 9.3 kg; 7 controls: 22.4 +/- 3.0 years, 182.4 +/- 6.9 cm, 85.3 +/- 10.5 kg) participated in this study. The subjects were tested 3 times: 11 weeks (TEST1), 5 weeks (TEST2), and 3 days (TEST3) before the national championships...
February 2008: Metabolism: Clinical and Experimental
I Iványi, B Kispélyi, A Lázár, A Balogh, L Rosivall, I Nyárasdy
Materials employed in "adhesive filling technique" often lack informative instructions concerning the depth of cavities which require lining. Etching-materials directly placed on the dentin can adversely influence the pulp leading to changes in local microcirculation which can be an early sign of the pathological changes in the pulp. Therefore, it is worth examining the effect of these materials on the diameters of pulpal vessels. In the present study we examined wether acid etching (test1: 15 s and test2: 60 s) alters the blood circulation of the pulp lower incisors, by applying it directly onto a thin layer of pulpal wall (40-50 microns) without any liner, and following the instructions provided by the manufacturer...
March 2000: Fogorvosi Szemle
I Iványi, A E Balogh, L Rosivall, I Nyárasdy
No data are available on the direct acute vascular effect of dental bond materials in the dental pulp. The purpose of the present study was to investigate the effect of composite resin bonding systems on the pulpal vascular diameter. Three groups of male Sprague-Dawley rats (weighing 300-490 g), each of 10 animals were used for this investigation. The left lower incisor of the rats was prepared for vitalmicroscopy. Changes in vessel diameter were recorded prior to; and 5, 15, 30, 60 minutes after the application of saline (control) or the bonding agents (test1: acetone containing--/Prime/Bond2...
May 1999: Fogorvosi Szemle
I Setnikar, L C Rovati, K Schmid, B Vens-Cappell, M F Barkworth
Two studies on the rate and extent of bioavailability of fluoride from a single dose of oral preparations of sodium monofluorophosphate (Na2FPO3) combined with calcium supplement were conducted according to a cross-over design on 18 (Study 1) and 20 (Study 2) male healthy volunteers, respectively. Evaluated were: a) tablets containing 76 mg Na2FPO3 (Ref1); b) chewable tablets containing 76 mg Na2FPO3 and 1250 mg calcium carbonate (Test 1); c) effervescent tablets containing 76 mg Na2FPO and 3240 mg calcium lactogluconate/carbonate (Ref 2); d) effervescent tablets containing 76 mg Na2FPO3 and 1250 mg calcium carbonate (Test 2)...
December 1998: Arzneimittel-Forschung
S al-Adawi, J Powell
AIMS: To investigate the effects of (a) nicotine abstinence and (b) cigarette smoking after abstinence, on reward responsiveness and cognitive functions which are putatively dependent on activity in the dopaminergic system implicated in smoking. DESIGN: During Ramadhan, Muslim smokers elected to abstain from smoking either for the whole month (RAMQUIT) or during daylight hours (DAYQUIT). These groups, and non-smokers (NOSMOKE), were assessed on two occasions 6 hours apart (TEST1 and TEST2)...
December 1997: Addiction
J W Rankin, J V Ocel, L L Craft
Collegiate wrestlers (N = 12) consumed a formula, hypoenergy diet (18, 60% carbohydrate) without dehydration for 72 h. For the next 5 h, the athletes were fed either a 75% (HC) or a 47% (MC) carbohydrate formula diet of 21 Each wrestler performed three anaerobic arm ergometer performance tests (TEST1, before weight loss; TEST2, after weight loss; TEST3, after refeeding). Blood withdrawn just before and after each test was analyzed for pH, bicarbonate, base excess, glucose, and lactate. Both groups had a similar significant reduction in total work done during TEST2 (92...
October 1996: Medicine and Science in Sports and Exercise
E E Castilla, I M Orioli, R Lugarinho, G P Dutra, J S Lopez-Camelo, H E Campana, A Spagnolo, P Mastroiacovo
Three large and comparable series of births were used to test the working hypothesis that if there is a real seasonal variation in the frequency of a given congenital malformation; it would have to be shown by adequate analysis; to be more overt in non-tropical areas; and to be six months out of phase in northern and southern hemispheres. The data set were hospital births from tropical (287,165 births) and non-tropical (582,585 births) South America, and from Italy (508,536 births). Sixteen well-defined malformation types were tested: anencephaly, spina bifida, cephalocoele, hydrocephaly, microtia, cleft palate, cleft lip, oesophageal atresia, anal atresia, hypospadias, pes equino-varus, pes talovalgus, postaxial polydactylyl, pre-axial polydactylyl, diaphragmatic hernia, and Down's syndrome...
June 1990: International Journal of Epidemiology
H Sugimoto, N Ishii, A Iwata, N Suzumura
Biomedical data, such as EEG, EMG and neural impulse sequences, are regarded as the stochastic phenomena of biological systems, and the statistical properties of such time series are often examined. Most of the statistical analysis processed in the frequency and the time domain are based on the assumption that the time series is weakly stationary and normally distributed. Therefore, as the basis of the statistical analysis of the biomedical data, it is necessary to know whether they satisfy the conditions of weak stationarity and normality...
December 1977: Computer Programs in Biomedicine
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