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https://www.readbyqxmd.com/read/28214236/are-hospital-ed-transfers-less-likely-among-nursing-home-residents-with-do-not-hospitalize-orders
#1
Taeko Nakashima, Yuchi Young, Wan-Hsiang Hsu
OBJECTIVES: This study aims to examine whether an advance directive "Do Not Hospitalize" (DNH) would be effective in reducing hospital/emergency department (ED) transfers. Similar effects in residents with dementia were also examined. DESIGN: Cross-sectional study. SETTING/SUBJECTS: New York State (NYS) nursing home residents (n = 43,024). MEASUREMENTS AND ANALYSIS: The Minimum Data Set 2.0 was used to address the study aims...
February 14, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28213440/muscle-yap-is-a-regulator-of-neuromuscular-junction-formation-and-regeneration
#2
Kai Zhao, Chengyong Shen, Yisheng Lu, Zhihui Huang, Lei Li, Christopher D Rand, Jinxiu Pan, Xiang-Dong Sun, Zhibing Tan, Hongsheng Wang, Guanglin Xing, Yu Cao, Guoqing Hu, Jiliang Zhou, Wen-Cheng Xiong, Lin Mei
Yes-associated protein (Yap) is a major effector of the Hippo pathway that regulates cell proliferation and differentiation during development and restricts tissue growth in adult animals. However, its role in synapse formation remains poorly understood. In this study, we characterized Yap's role in the formation of neuromuscular junction (NMJ). In HSA-Yap(-/-) mice where Yap was mutated specifically in muscle cells, AChR clusters were smaller and were distributed in a broader region in the middle of muscle fibers, suggesting that muscle Yap is necessary for the size and location of AChR clusters...
February 17, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28212161/hearing-impairment-and-the-amelioration-of-avoidable-medical-error-a-cross-sectional-survey
#3
Patrick Henn, Colm OʼTuathaigh, Darrelle Keegan, Simon Smith
OBJECTIVES: Hearing loss contributes to suboptimal medical treatment. We investigated the nature and magnitude of potential health-care harm of hearing loss alone on a patient's understanding of medical consultations, investigations, and treatments of health conditions unrelated to their hearing loss. METHODS: A cross-sectional, questionnaire-based design of a convenience sample of students with hearing loss, registered with the institutional disability support service in 8 Irish and 15 UK third-level institutions...
February 16, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28209693/rebuttal-should-family-physicians-prescribe-medication-for-obesity-yes
#4
Laura Bourns, Judy Shiau
No abstract text is available yet for this article.
February 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28209667/should-family-physicians-prescribe-medication-for-obesity-yes
#5
Laura Bourns, Judy Shiau
No abstract text is available yet for this article.
February 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28203418/clinical-outcomes-of-surgically-resected-combined-small-cell-lung-cancer-a-two-institutional-experience
#6
Chao Zhang, Haitang Yang, Heng Zhao, Baoping Lang, Xiangdong Yu, Peng Xiao, Xiao Zhang
BACKGROUND: The combined small cell lung cancer (c-SCLC) was rare and its clinicopathological characteristics had not been thoroughly described. The aim of this study was to determine prognostic factors and survival in c-SCLC patients. METHODS: Clinical records of patients with c-SCLC who underwent surgery between January 2009 and December 2013 in two institutions were retrospectively reviewed. RESULTS: Ninety-seven patients were identified...
January 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28197783/freezing-nitrogen-ethanol-composite-may-be-a-viable-approach-for-cryotherapy-of-human-giant-cell-tumor-of-bone
#7
Po-Kuei Wu, Cheng-Fong Chen, Jir-You Wang, Paul Chih-Hsueh Chen, Ming-Chau Chang, Shih-Chieh Hung, Wei-Ming Chen
BACKGROUND: Liquid nitrogen has been used as adjuvant cryotherapy for treating giant cell tumor (GCT) of bone. However, the liquid phase and ultrafreezing (-196° C) properties increase the risk of damage to the adjacent tissues and may lead to perioperative complications. A novel semisolid cryogen, freezing nitrogen ethanol composite, might mitigate these shortcomings because of less-extreme freezing. We therefore wished to evaluate freezing nitrogen ethanol composite as a coolant to determine its properties in tumor cryoablation...
February 14, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28196718/the-neuropeptide-galanin-is-up-regulated-during-cholestasis-and-contributes-to-cholangiocyte-proliferation
#8
Matthew McMillin, Gabriel Frampton, Stephanie Grant, Sharon DeMorrow
During the course of cholestatic liver diseases, mitotically dormant cholangiocytes proliferate and subsequently acquire a neuroendocrine phenotype. Galanin is a neuroendocrine factor responsible for regulation of physiological responses, such as feeding behavior and mood, and has been implicated in the development of fatty liver disease, although its role in biliary hyperplasia is unknown. Biliary hyperplasia was induced in rats via bile duct ligation (BDL) surgery, and galanin was increased in serum and liver homogenates from BDL rats...
February 11, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28194996/lithium-classic-yes-first-line-%C3%A2-only-sometimes
#9
Michael Gitlin
No abstract text is available yet for this article.
February 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28194512/should-all-patients-with-sepsis-receive-anticoagulation-yes
#10
EDITORIAL
Ferhat Meziani, Satoshi Gando, Jean-Louis Vincent
No abstract text is available yet for this article.
February 13, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28193600/smartphone-based-self-assessment-of-stress-in-healthy-adult-individuals-a-systematic-review
#11
Helga Þórarinsdóttir, Lars Vedel Kessing, Maria Faurholt-Jepsen
BACKGROUND: Stress is a common experience in today's society. Smartphone ownership is widespread, and smartphones can be used to monitor health and well-being. Smartphone-based self-assessment of stress can be done in naturalistic settings and may potentially reflect real-time stress level. OBJECTIVE: The objectives of this systematic review were to evaluate (1) the use of smartphones to measure self-assessed stress in healthy adult individuals, (2) the validity of smartphone-based self-assessed stress compared with validated stress scales, and (3) the association between smartphone-based self-assessed stress and smartphone generated objective data...
February 13, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28191735/caregiving-related-needs-of-family-caregivers-of-older-singaporeans
#12
Shweta Ajay, Truls Østbye, Rahul Malhotra
AIM: To describe the extent and correlates of caregiving-related needs among family caregivers of Singaporeans aged 75+ with ≥1 activity of daily living limitations (care-recipients). METHODS: National survey data of 1181 care-recipient/caregiver dyads were used. Caregiver's report (yes/no) of 16 needs was assessed. Care-recipient and caregiver correlates of each need were determined through logistic regression analysis. RESULTS: Caregiving-related needs were expressed by 42...
February 13, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28190999/higher-drop-in-speed-during-a-repeated-sprint-test-in-soccer-players-reporting-former-hamstring-strain-injury
#13
Ola D Røksund, Morten Kristoffersen, Bård E Bogen, Alexander Wisnes, Merete S Engeseth, Ann-Kristin Nilsen, Vegard V Iversen, Silje Mæland, Hilde Gundersen
Aim: Hamstring strain injury is common in soccer. The aim of this study was to evaluate the physical capacity of players who have and have not suffered from hamstring strain injury in a sample of semi-professional and professional Norwegian soccer players in order to evaluate characteristics and to identify possible indications of insufficient rehabilitation. Method: Seventy-five semi-professional and professional soccer players (19 ± 3 years) playing at the second and third level in the Norwegian league participated in the study...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28190896/yoga-and-other-meditative-movement-therapies-to-reduce-chronic-pain
#14
Allison Achilefu, Kunal Joshi, Megan Meier, Laine H McCarthy
CLINICAL QUESTION: In adults with chronic pain, do yoga and other meditative movement therapies to improvement in chronic pain symptoms? ANSWER: Yes. However, in each of the studies reviewed, yoga classes were included as part of the pain management regime, sometimes alone and sometimes in tandem with DVDs or audiotapes. We feel that no exercise therapy program should be undertaken without professional coaching from certified, registered and qualified instructors...
January 2017: Journal of the Oklahoma State Medical Association
https://www.readbyqxmd.com/read/28188585/assessing-the-effects-of-interpersonal-and-intrapersonal-behavior-change-strategies-on-physical-activity-in-older-adults-a-factorial-experiment
#15
Siobhan K McMahon, Beth Lewis, J Michael Oakes, Jean F Wyman, Weihua Guan, Alexander J Rothman
BACKGROUND: Little is known about which behavior change strategies motivate older adults to increase their physical activity. PURPOSE: The purpose of this study was to assess the relative effects of two sets of behavior change strategies to motivate increased physical activity among older adults: interpersonal and intrapersonal. METHODS: Community-dwelling older adults (N = 102, mean age = 79) were randomized in a 2 × 2 factorial experiment to receive interpersonal (e...
February 10, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/28186843/risks-and-cough-aggravating-factors-in-prolonged-cough-epidemiological-observations-from-the-nagahama-cohort-study
#16
Hisako Matsumoto, Yumi Izuhara, Akio Niimi, Yasuharu Tabara, Tadao Nagasaki, Yoshihiro Kanemitsu, Kimihiko Murase, Tsuyoshi Oguma, Isao Ito, Shigeo Muro, Akihiro Sekine, Fumihiko Matsuda, Shinji Kosugi, Takeo Nakayama, Kazuo Chin, Michiaki Mishima
RATIONALE: Chronic cough hypersensitivity, a potentially important concept of chronic or prolonged cough, is featured by heightened cough response to low-intensity stimuli, which may be generated in the absence of airflow limitations or allergic conditions. However, there is little epidemiological evidence to support this. OBJECTIVES: In this large-scale community survey, we aimed to determine risks and cough-aggravating factors of prolonged cough, while focusing on serum IgE levels...
February 10, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28186462/posttraumatic-growth-following-the-loss-of-a-pet
#17
Cori Bussolari, Janice Habarth, Satoko Kimpara, Rachel Katz, France Carlos, Amy Chow, Hisao Osada, Yukiko Osada, Betty J Carmack, Nigel P Field, Wendy Packman
The current study examined Posttraumatic Growth (PTG) experienced by bereaved pet owners in the United States, French-Canada, Japan, and Hong Kong following the death of their pet. Using qualitative methodology, we analyzed responses of participants who answered "yes" to a question about experiencing PTG and explored to what extent the cross-cultural responses mapped onto the five factors of the Posttraumatic Growth Inventory (PTGI). For the U.S. sample, 58% of responses mapped onto the PTGI. For French-Canada, 72% of responses mapped onto the PTGI...
January 1, 2017: Omega
https://www.readbyqxmd.com/read/28186153/superresolution-imaging-of-nanoscale-chromosome-contacts
#18
Yejun Wang, Prasuna Ratna, G V Shivashankar
Co-expression of a specific group of genes requires physical associations among these genes, which form functional chromosomal contacts. While DNA fluorescence in situ hybridization (FISH) pinpoints the localization of genes within the 3D nuclear architecture, direct evidence of physical chromosomal contacts is still lacking. Here, we report a method for the direct visualization of transcription-dependent chromosomal contacts formed in two distinct mechanical states of cells. We prepared open chromatin spreads from isolated nuclei, ensuring 2D rendering of chromosome organization...
February 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28184971/yes-we-can-analyse-amyloid-images-now-what
#19
EDITORIAL
Henryk Barthel, John Seibyl, Osama Sabri
No abstract text is available yet for this article.
February 9, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28183060/toxic-and-endocrine-disrupting-effects-of-wastewater-treatment-plant-influents-and-effluents-on-a-freshwater-isopod-asellus-aquaticus-isopoda-crustacea
#20
Maja Plahuta, Tatjana Tišler, Mihael Jožef Toman, Albin Pintar
In the present study a biological "in vivo" assay, with freshwater isopod Asellus aquaticus, was used to define and evaluate the potential impact of the wastewater treatment plant (WWTP) wastewaters on local wildlife. Samples of both untreated and mechanically and biologically treated WWTP wastewater, were tested in the presence and absence of the formulated sediment for their lethal and sublethal effects. Chronic exposures to wastewater samples caused concentration dependent reduced locomotion, body pigmentation and molting frequency in exposed organisms...
January 31, 2017: Chemosphere
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