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https://www.readbyqxmd.com/read/29783200/blood-lead-and-cadmium-levels-in-preschool-children-and-associated-risk-factors-in-s%C3%A3-o-paulo-brazil
#1
Kelly Polido Kaneshiro Olympio, Júlia Prestes da Rocha Silva, Agnes Soares da Silva, Vanessa Cristina de Oliveira Souza, Marília Afonso Rabelo Buzalaf, Fernando Barbosa, Maria Regina Alves Cardoso
In Brazil, there are scarce data on lead (Pb) and cadmium (Cd) contamination, especially for more vulnerable populations such as preschool children. In this paper, we answer two questions: (1) What are the exposure levels of lead and cadmium in preschool children, in Sao Paulo, Brazil? and (2) What are the risk factors associated with this exposure? This cross-sectional study included 50 day care centers (DCCs), totaling 2463 children aged 1-4 years. Venous blood samples were analyzed by ICP-MS. Questionnaires were administered to the parents...
May 18, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29783196/activity-concentrations-of-238-u-and-226-ra-in-two-european-black-shales-and-their-experimentally-derived-leachates
#2
Franziska D H Wilke, Georg Schettler, Andrea Vieth-Hillebrand, Michael Kühn, Heike Rothe
The production of gas from unconventional resources became an important position in the world energy economics. In 2012, the European Commission's Joint Research Centre estimate 16 trillion cubic meters (Tcm) of technically recoverable shale gas in Europe. Taking into account that the exploitation of unconventional gas can be accompanied by serious health risks due to the release of toxic chemical components and natural occurring radionuclides into the return flow water and their near-surface accumulation in secondary precipitates, we investigated the release of U, Th and Ra from black shales by interaction with drilling fluids containing additives that are commonly employed for shale gas exploitation...
May 18, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29783138/is-death-anxiety-more-closely-linked-with-optimism-or-pessimism-among-older-adults
#3
Michael D Barnett, Ellen A Anderson, Arthur D Marsden
The purpose of this study was to investigate whether death anxiety is more closely linked with optimism or pessimism among older adults. Participants consisted of community-dwelling older adults (N = 253; 73.1% female) in the southern U.S. Both optimism and pessimism demonstrated a bivariate association with death anxiety; however, when considering optimism and pessimism together-and after controlling for age, gender, physical health, and mental health-optimism was not associated with death anxiety, while pessimism was associated with higher death anxiety...
May 18, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29783109/anti-inflammatory-potential-of-alginic-acid-from-sargassum-horneri-against-urban-aerosol-induced-inflammatory-responses-in-keratinocytes-and-macrophages
#4
I P Shanura Fernando, Thilina U Jayawardena, K K Asanka Sanjeewa, Lei Wang, You-Jin Jeon, Won Woo Lee
The airborne particulate pollutants originating in the deserts of Mongolia and China which becomes contaminated with industrial effluents and traffic emissions while moving with the wind currents towards East Asia has recently become a serious environmental and health issue in the region. They cause asthma, collateral lung tissue damage, oxidative stress, allergic reactions, and inflammation. The current study was undertaken to evaluate the protective effects of alginate extracted from the invasive alga Sargassum horneri (SHA) against fine dust collected from Beijing, China (Chinese fine dust; CFD)...
May 18, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29783090/inter-and-intra-disciplinary-collaboration-and-patient-safety-outcomes-in-u-s-acute-care-hospital-units-a-cross-sectional-study
#5
Chenjuan Ma, Shin Hye Park, Jingjing Shang
BACKGROUND: Collaboration among healthcare providers has been considered a promising strategy for improving care quality and patient outcomes. Despite mounting evidence demonstrating the impact of collaboration on outcomes of healthcare providers, there is little empirical evidence on the relationship between collaboration and patient safety outcomes, particularly at the patient care unit level. OBJECTIVES: The purpose of this study is to identify the extent to which interdisciplinary collaboration between nurses and physicians and intradisciplinary collaboration among nurses on patient care units are associated with patient safety outcomes...
May 2, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29783078/delayed-bipolar-and-ganglion-cells-neuroretinal-processing-in-regular-cannabis-users-the-retina-as-a-relevant-site-to-investigate-brain-synaptic-transmission-dysfunctions
#6
Thomas Schwitzer, Raymund Schwan, Karine Angioi-Duprez, Anne Giersch, Laurence Lalanne, Eliane Albuisson, Vincent Laprevote
Cannabis use is widespread worldwide, but the impact of smoking cannabis regularly on brain synaptic transmission has only been partially elucidated. The retina is considered as an easy means of determining dysfunction in brain synaptic transmission. The endocannabinoid system is involved in regulating retinal synaptic transmission, which might also be affected by tobacco. Previous preliminary results have shown impairments in retinal ganglion cell response in cannabis users. Here, we test the extent to which earlier retinal levels-bipolar cells and photoreceptors-are affected in cannabis users, i...
May 1, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29783077/effects-of-prolonged-exposure-and-virtual-reality-exposure-on-suicidal-ideation-in-active-duty-soldiers-an-examination-of-potential-mechanisms
#7
REVIEW
Aaron M Norr, Derek J Smolenski, Greg M Reger
OBJECTIVE: The current study sought to investigate the effects of exposure therapy on suicidal ideation (SI), as well as potential mechanistic pathways of SI reduction among active duty military personnel. METHODS: Active duty army soldiers (N = 162) were recruited from a military base in the U.S. and were enrolled in a randomized clinical trial comparing Prolonged Exposure (PE), Virtual Reality Exposure (VRE), and a wait-list control for the treatment of posttraumatic stress disorder (PTSD) stemming from deployments to Iraq or Afghanistan...
May 12, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29783053/biomineralization-mechanism-of-u-vi-induced-by-bacillus-cereus-12-2-the-role-of-functional-groups-and-enzymes
#8
Jian Zhang, Han Song, Zhi Chen, Shasha Liu, Yali Wei, Jingyi Huang, Chuling Guo, Zhi Dang, Zhang Lin
Current studies reveal that the biomineralization of U(VI) by anaerobes normally produces nano-sized U(IV) minerals that can easily re-migrate/re-oxidize, while the biomineralization of U(VI) by aerobes has been constrained because the general mechanism has not yet been fully characterized. The biomineralization of U(VI) by Bacillus cereus 12-2 was investigated in this work. The maximum biosorption capability of intact cells was 448.68 mg U/g biomass (dry weight) at pH 5, while a decrease over 60% was induced when phosphate, amino, and especially carboxyl groups were shielded...
May 10, 2018: Chemosphere
https://www.readbyqxmd.com/read/29783006/technique-of-whole-sellar-stereotactic-radiosurgery-for-cushing-s-disease-results-from-a-multicenter-international-cohort-study
#9
Matthew J Shepard, Gautam U Mehta, Zhiyuan Xu, Hideyuki Kano, Nathaniel Sisterson, Yan-Hua Su, Michal Krsek, Ahmed M Nabeel, Amr El-Shehaby, Khaled A Kareem, Nuria Martinez-Moreno, David Mathieu, Brendan J McShane, Kevin Blas, Douglas Kondziolka, Inga Grills, John Y Lee, Roberto Martinez-Alvarez, Wael A Reda, Roman Liscak, Cheng-Chia Lee, L Dade Lunsford, Mary Lee Vance, Jason P Sheehan
BACKGROUND: Stereotactic radiosurgery (SRS) is used to manage patients with Cushing's disease (CD) who have failed surgical/medical management. As many patients with recurrent/persistent CD lack an identifiable adenoma on neuro-imaging, whole-sellar SRS has been increasingly employed. We therefore sought to define the outcomes of patients undergoing whole-sellar SRS. METHODS: An international, multicenter, retrospective cohort-design was used to define clinical/endocrine outcomes for patients undergoing whole-sellar SRS for CD...
May 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29782995/efficacy-of-antipsychotics-in-dementia-depended-on-the-definition-of-patients-and-outcomes-a-meta-epidemiological-study
#10
REVIEW
C H W Smeets, S U Zuidema, T A Hulshof, M Smalbrugge, D L Gerritsen, R T C M Koopmans, H J Luijendijk
OBJECTIVE: Postulating that efficacy of antipsychotics for agitation and psychosis in dementia is best estimated in trials among patients with these symptoms and with symptom-specific outcomes, we investigated whether clinically broader definitions affected the pooled efficacy. STUDY DESIGN AND SETTING: Trials were searched in multiple databases and categorized according to patient population (agitated, psychotic, mixed) and outcome scale (agitation, psychosis, generic)...
May 18, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29782967/deficient-mitochondrial-biogenesis-in-il-2-activated-nk-cells-correlates-with-impaired-pgc1-%C3%AE-upregulation-in-elderly-humans
#11
Dante Miranda, Claudia Jara, Sophia Mejias, Viviana Ahumada, Marcelo Cortez-San Martin, Jorge Ibañez, Sandra Hirsch, Margarita Montoya
Immunosenescence has been described as age-associated changes in the immune function which are thought to be responsible for the increased morbidity with age. Human Natural Killer (NK) cells are a specialized heterogeneous subpopulation of lymphocytes involved in immune defense against tumor and microbial diseases. Interestingly, aging-related NK cell dysfunction is associated with features of aging such as tumor incidence, reduced vaccination efficacy, and short survival due to infection. It is known that NK cell effector functions are critically dependent on cytokines and metabolic activity...
May 18, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29782937/health-disparities-among-children-with-asthma-in-the-u-s-by-place-of-residence
#12
Patrick W Sullivan, Vahram Ghushchyan, Abhishek Kavati, Prakash Navaratnam, Howard S Friedman, B Ortiz
BACKGROUND: Children residing in poor-urban areas may have greater asthma morbidity. It is unclear if this is due to individual characteristics like race and ethnicity or place of residence. OBJECTIVE: Assess indicators of control and treatment by residence. METHODS: This was a cross-sectional analysis of children (aged 1-17) in the 2000-2014 Medical Expenditure Panel Survey (MEPS). Indicators of poor control included use of > 3 canisters of short-acting beta agonist (SABA) in 3 months, asthma attack, and Emergency Department (ED) or inpatient (IP) visit during the year...
May 18, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29782592/the-role-of-hybrid-bone-spect-ct-imaging-in-the-work-up-of-the-limping-patient-a-symptom-based-and-joint-oriented-review
#13
REVIEW
H K Mohan, K Strobel, W van der Bruggen, G Gnanasegaran, W U Kampen, T Kuwert, T Van den Wyngaert, F Paycha
A vast spectrum of lower limb bone and joint disorders (hip, knee, ankle, foot) present with a common clinical presentation: limping. Too often this symptom generates an inefficient cascade of imaging studies. This review attempts to optimise the diagnostic effectiveness of bone scintigraphy using the hybrid SPECT/CT technique in relation to the diagnostic clues provided by other imaging modalities, discusses the appropriate clinical indications, optimal scintigraphic procedures and illustrates updated image pattern-oriented reporting...
2018: Eur J Hybrid Imaging
https://www.readbyqxmd.com/read/29782443/association-between-vestibular-vertigo-and-motor-vehicle-accidents-data-from-the-2016-national-health-interview-survey
#14
Eric X Wei, Yuri Agrawal
Recent evidence has shown that individuals with vestibular impairment have higher rates of self-reported driving difficulty compared with individuals without vestibular impairment. However, it is unknown whether individuals with vestibular impairment are more likely to be involved in motor vehicle accidents. We used data from the 2016 National Health Interview Survey of U.S. adults to evaluate whether individuals with vestibular vertigo are more likely to experience motor vehicle accidents relative to individuals without vestibular vertigo...
May 18, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29782442/informational-masking-effects-on-neural-encoding-of-stimulus-onset-and-acoustic-change
#15
Christopher E Niemczak, Kathy R Vander Werff
OBJECTIVE: Recent investigations using cortical auditory evoked potentials have shown masker-dependent effects on sensory cortical processing of speech information. Background noise maskers consisting of other people talking are particularly difficult for speech recognition. Behavioral studies have related this to perceptual masking, or informational masking, beyond just the overlap of the masker and target at the auditory periphery. The aim of the present study was to use cortical auditory evoked potentials, to examine how maskers (i...
May 18, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29782424/the-profile-of-serum-transferrin-isoforms-in-rheumatoid-arthritis
#16
Monika Gudowska, Ewa Gruszewska, Alicja Wrona, Ewa Gindzienska-Sieskiewicz, Izabela Domyslawska, Karina Lipartowska-Klimuk, Bogdan Cylwik, Stanislaw Sierakowski, Lech Chrostek
INTRODUCTION: Transferrin, a microheterogeneous iron-transporting N-glycoprotein, is an optimal model for the analysis of the glycosylation profile in rheumatoid arthritis. The aim of this study was to assess the transferrin isoforms profile in RA patients at the time of diagnosis and then look into the associations with disease activity. METHODS: Serum samples were collected from 48 patients with rheumatoid arthritis. The patients were males (6) and females (42) (age range: 33-85 years)...
May 19, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29782332/detection-of-high-risk-thrombophilia-with-an-automated-global-test-the-coagulation-inhibitor-potential-assay
#17
Barbara Réger, Hajna Losonczy, Ágnes Nagy, Ágnes Péterfalvi, Réka Mózes, László Pótó, Nelli Farkas, Gábor L Kovács, Attila Miseta, Alizadeh Hussain, Orsolya Tóth
: The diagnosis of thrombophilia is a cost-consuming and time-consuming process, as each defect should be separately investigated. The Coagulation Inhibitor Potential (CIP) assay is a promising new global test, sensitive for most of the hereditary thrombophilias, developed for manual methodology. We adapt the original method to an optical coagulation analyser. By this automation, the test will be easier, faster and more precise, and it also allows carrying out 18 measurements simultaneously. The CIP assay was performed in 126 healthy subjects and 193 patients with different types of hereditary thrombophilia conditions...
May 17, 2018: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29782292/evaluation-of-symptomatic-patients-with-resistant-discharge
#18
Cemile Sonmez, Selma Usluca, Ismail Hakki Usluca, Irem Kalipci, Figen Sezen, Cemal Resat Atalay, Selcuk Kilic
The aim of this study was to detect the presence of Chlamydia trachomatis, Neisseria (N.) gonorrhoeae, Mycoplasma (M.) hominis, M. genitalium, Ureaplasma (U.) urealyticum, and Trichomonas (T.) vaginalis in patients with resistant discharge. The study also evaluated the concordance of the diagnostic tests. Samples from 156 patients were tested by direct microscopy and culture for T. vaginalis and Mycoplasma IES for M. hominis and U. urealyticum. Multiplex Polymerase Chain Reaction (PCR) was used to determine the presence of six agents...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782286/-ngal-as-a-marker-for-some-extrarenal-complications-in-acute-coronary-syndrome
#19
M A Shalenkova, Z D Mikhailova, P F Klimkin
AIM: To study the role of neutrophil gelatinase-associated lipocalin (NGAL) as a marker for extrarenal complications in patients with acute coronary syndrome (ACS). MATERIALS AND METHODS: For 110 patients with ACS on days 1-3 of hospitalization, concentrations of NGAL, serum (s-NGAL) and urinary (u-NGAL) NGAL, and N-terminal fragment of pro-B natriuretic peptide (NT-proBNP) were measured, and transthoracic echocardiography was performed. Incidence of cardiovascular complications was determined during the stay in the hospital; hemodynamic parameters (systolic and diastolic blood pressure, heart rate) were measured on admission...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29782218/postural-control-and-physiological-responses-to-a-simulated-match-in-u-20-judo-competitors
#20
Luis Santos, Javier Fernández-Río, Eliseo Iglesias-Soler, Miguel Blanco-Traba, Markus Due Jakobsen, Vicente González-Díez, Emerson Franchini, Carlos Gutiérrez, Xurxo Dopico-Calvo, Eduardo Carballeira-Fernández, William Amonette, Oscar Suman
The aim was to evaluate the effects of judo combat on the athletes' postural control (PC) and physiological loading before, during and after a simulated match. Seventeen under-20 regional and national level athletes completed one modified 7-min match. At baseline, during the combat (3rd and 7th minutes) and 2-min post-match centre of pressure (CoP) parameters were assessed. Heart rate (HR), blood lactate (BLa) and rating of perceived exertion (RPE) and local RPE (LRPE) were collected. Significant increments were observed in CoP mean positioning and velocity at 3rd and 7th minutes, but the CoP deviation in both axes was unaffected...
May 21, 2018: Sports Biomechanics
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