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https://www.readbyqxmd.com/read/27904002/diffuse-mesangial-sclerosis-in-a-child-with-dyskeratosis-congenita-leading-to-end-stage-renal-disease
#1
Abidi Kamel, Taha Sayari, Manel Jellouli, Yousra Hammi, Rim Ghoucha Louzir, Tahar Gargah
Dyskeratosis congenita (DC) is a very rare inherited disorder. It is caused by dysfunction of telomere maintenance. It involves RNA telomerase components relevant to various mutations leading to a classic triad of physical findings consisting of nail dystrophy of the hands and feet, mucosal leukoplakia, and reticular pigmentation of the skin, most commonly on the head, neck, and trunk. Bone marrow failure along with pulmonary complications and malignancies are all common causes of premature death in patients with DC as well as other abnormalities...
November 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/27895619/a-functional-magnetic-resonance-imaging-study-of-head-movements-in-cervical-dystonia
#2
Cecília N Prudente, Randall Stilla, Shivangi Singh, Cathrin Buetefisch, Marian Evatt, Stewart A Factor, Alan Freeman, Xiaoping Philip Hu, Ellen J Hess, K Sathian, H A Jinnah
Cervical dystonia (CD) is a neurological disorder characterized by abnormal movements and postures of the head. The brain regions responsible for these abnormal movements are not well understood, because most imaging techniques for assessing regional brain activity cannot be used when the head is moving. Recently, we mapped brain activation in healthy individuals using functional magnetic resonance imaging during isometric head rotation, when muscle contractions occur without actual head movements. In the current study, we used the same methods to explore the neural substrates for head movements in subjects with CD who had predominantly rotational abnormalities (torticollis)...
2016: Frontiers in Neurology
https://www.readbyqxmd.com/read/27894579/future-perspectives-of-pre-expanded-perforator-flaps
#3
REVIEW
Lee L Q Pu, Chunmei Wang
Although clinical application of a pre-expanded perforator flap is primarily focused on face and neck reconstructions, such a flap has also been used to reconstruct defects in the trunk, extremities, or hands. With better understanding of the improved blood supply to the flap and the mechanism on the prefabrication of blood supply within the flap, the pre-expanded perforator flap will definitely play a more important role in reconstructive surgery and can be used in selected patients by many plastic surgeons worldwide with good reconstructive and cosmetic outcomes...
January 2017: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/27892984/anatomical-distributions-of-basal-cell-carcinoma-and-squamous-cell-carcinoma-in-a-population-based-study-in-queensland-australia
#4
Padmini Subramaniam, Catherine M Olsen, Bridie S Thompson, David C Whiteman, Rachel E Neale
Importance: Keratinocyte cancers (KCs), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common cancers among fair-skinned populations worldwide. Although studies have indicated that the anatomical distribution of BCC and SCC differ, few have compared them directly in well-defined population samples. Objectives: To describe and compare the anatomical distribution of BCC and SCC in a population-based sample in Queensland, Australia...
November 23, 2016: JAMA Dermatology
https://www.readbyqxmd.com/read/27891170/prevalence-and-predictors-of-musculoskeletal-pain-among-danish-fishermen-results-from-a-cross-sectional-survey
#5
Gabriele Berg-Beckhoff, Helle Østergaard, Jørgen Riis Jepsen
BACKGROUND: Fishermen work in a physically challenging work environment. The aim of this analysis was to estimate the prevalence and predictors of musculoskeletal pain among Danish fishermen. METHOD: A cross-sectional survey in a random sample of Danish fishermen was done with application of the Nordic questionnaire regarding musculoskeletal pain considering lower back, shoulders, hand neck, knee, upper back elbow, hip and feet. In total, 270 fishermen participated in the study (response rate: 28%)...
2016: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/27886079/cerebellar-intermittent-theta-burst-stimulation-and-motor-control-training-in-individuals-with-cervical-dystonia
#6
Lynley V Bradnam, Michelle N McDonnell, Michael C Ridding
BACKGROUND: There is emerging evidence that cervical dystonia is a neural network disorder with the cerebellum as a key node. The cerebellum may provide a target for neuromodulation as a therapeutic intervention in cervical dystonia. OBJECTIVE: This study aimed to assess effects of intermittent theta-burst stimulation of the cerebellum on dystonia symptoms, quality of life, hand motor dexterity and cortical neurophysiology using transcranial magnetic stimulation...
November 23, 2016: Brain Sciences
https://www.readbyqxmd.com/read/27885587/assaults-against-u-s-law-enforcement-officers-in-the-line-of-duty-situational-context-and-predictors-of-lethality
#7
Cassandra K Crifasi, Keshia M Pollack, Daniel W Webster
BACKGROUND: Research on occupational safety of law enforcement officers (LEOs) has primarily focused on fatal assaults. Nonfatal assaults, however, have received little attention. The goal of this study was to describe the situational contexts in which LEOs are assaulted, and compare these contexts and risks between fatal and nonfatal assaults in the U.S. Analyzing both types of assaults provides a more complete understanding of occupational safety and opportunities for intervention. METHODS: This study includes a descriptive epidemiology of fatal and nonfatal assaults of LEOs in the U...
December 2016: Injury Epidemiology
https://www.readbyqxmd.com/read/27882588/clinical-and-epidemiological-analysis-in-149-cases-of-rhododendrol-induced-leukoderma
#8
Momoko Yoshikawa, Yasuyuki Sumikawa, Tokimasa Hida, Takafumi Kamiya, Kimi Kase, Yasue Ishii-Osai, Junji Kato, Yuji Kan, Shiori Kamiya, Yuki Sato, Toshiharu Yamashita
Rhododendrol-induced leukoderma is an acquired depigmentation that develops mainly at the contact site after repeated use of skin-whitening cosmetics containing rhododendrol. In most cases, cessation of further depigmentation or occurrence of repigmentation is observed after discontinuing the use of cosmetics. However, some patients develop vitiligo vulgaris through the spread of depigmentation into the non-exposed areas. Our study aims to investigate the patient-specific factors that may affect the extent of depigmentation or repigmentation, as well as development of vitiligo vulgaris...
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27878131/extra-luminal-entrapment-of-guide-wire-a-rare-complication-of-central-venous-catheter-placement-in-right-internal-jugular-vein
#9
Md Abu Masud Ansari, Naveen Kumar, Shailesh Kumar, Sarita Kumari
Central venous Catheterization (CVC) is a commonly performed procedure for venous access. It is associated with several complications. We report a rare case of extra luminal entrapment of guide wire during CVC placement in right jugular vein. We report a case of 28 years old female patient presented in our emergency with history of entrapped guide wire in right side of neck during CVC. X-ray showed coiling of guide wire in neck. CT Angiography showed guide wire coursing in between common carotid artery and internal jugular vein (IJV), closely abutting the wall of both vessels...
October 2016: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/27876746/-the-cross-plastic-correction-of-the-soft-tissue-defect-on-the-neck-with-the-use-of-a-pectoral-flap-harvested-from-the-opposite-side
#10
A L Klochikhin, G I Markov, A L Chistyakov, N N Kosheleva
The authors describe a patient presenting with initially multiple metachronous cancer spreading over the right-handed side of the mouth floor and the right-handed part of the lower jaw. The patient who underwent cross-plastic surgery for the correction of the extensive soft tissue defect on the neck with the use of the musculocutaneous pectoral flap with the axial blood supply is described. The observation during the 14 year follow-up period confirmed the good functional outcome of the treatment.
2016: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/27872427/giant-lipoma-in-the-thigh-a-case-report
#11
Carlo de Werra, Gabriele di Filippo, Roberto Tramontano, Sergio Aloia, Rosa di Micco, Roberto Del Giudice
: Lipomas are the most common benign mesenchymal tumours; they are composed by mature lipocytes and are usually located in the subcutaneous tissue. They may occur at any place in which there is adipose tissue, most of them are found in the upper part of the body, especially in the trunk and neck, although they may also develop in other sites, including the hand. Most lipomas are small, weigh only a few grams, and usually the maximum diameter is smaller than 2 cm. Whereas, to be referred to as ''giant'', the lipoma must be at least 10 cm in diameter or weigh a minimum of 1,000 g...
November 21, 2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27865799/oleic-acid-induced-angptl4-enhances-head-and-neck-squamous-cell-carcinoma-anoikis-resistance-and-metastasis-via-up-regulation-of-fibronectin
#12
Chih-Jie Shen, Shih-Hung Chan, Chung-Ta Lee, Wan-Chen Huang, Jhih-Peng Tsai, Ben-Kuen Chen
Obese patients have higher levels of free fatty acids (FFAs) in their plasma and a higher risk of cancer than their non-obese counterparts. However, the mechanisms involved in the regulation of cancer metastasis by FFAs remain unclear. In this study, we found that oleic acid (OA) induced angiopoietin-like 4 (ANGPTL4) protein expression and secretion and conferred anoikis resistance to head and neck squamous cell carcinomas (HNSCCs). The autocrine production of OA-induced ANGPTL4 further promoted HNSCC migration and invasion...
November 16, 2016: Cancer Letters
https://www.readbyqxmd.com/read/27865371/assessing-head-and-neck-cancer-patient-preferences-and-expectations-a-systematic-review
#13
REVIEW
Pierre Blanchard, Robert J Volk, Jolie Ringash, Susan K Peterson, Katherine A Hutcheson, Steven J Frank
INTRODUCTION: To enhance the value of care, interventions should aim at improving endpoints that matter to patients. The preferences of head and neck cancer patients regarding treatment outcomes are therefore a major topic for patient-centered research. METHODS: A systematic review (PROSPERO number CRD42016035692) was conducted by searching electronic databases (Medline, Embase, Cochrane, CINAHL) for articles evaluating patient or surrogate preferences in head and neck cancer...
November 2016: Oral Oncology
https://www.readbyqxmd.com/read/27862223/effects-of-hip-implant-modular-neck-material-and-assembly-method-on-fatigue-life-and-distraction-force
#14
Fahad Aljenaei, Isabelle Catelas, Hakim Louati, Paul E Beaulé, Michel Nganbe
There is an urgent clinical need to develop accurate in vitro test procedures to better understand, predict and prevent in vivo implant failures. This study aimed to simulate in vivo fatigue fracture and distraction of modular necks in an in vitro setting, and to assess the effects of neck material (Ti6Al4V vs. CoCrMo) and assembly method (hand vs. impact) on implant failure. Fatigue tests were performed on the PROFEMUR® Modular Neck System under two different loads and number of cycles: 2.3 kN for 5 million cycles, and 7...
November 16, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27859810/high-prevalence-of-self-reported-shoulder-complaints-after-thyroid-carcinoma-surgery
#15
Sean H P P Roerink, Lien Coolen, Maria E Schenning, Olga Husson, Jan W A Smit, Henri A Marres, Johannes H W de Wilt, Romana T Netea-Maier
BACKGROUND: Shoulder complaints are frequently reported after surgical treatment for thyroid carcinoma. However, no specific literature on this topic is available for these patients and, hence, its impact on quality of life (QOL) is unknown and there are no known predictors of shoulder complaints in this specific patient population. Therefore, the purpose of this study was to assess the prevalence of shoulder-related complaints and its relation to QOL and clinical characteristics after thyroid carcinoma surgery by means of a cross-sectional case control study in a tertiary referral center...
November 12, 2016: Head & Neck
https://www.readbyqxmd.com/read/27857920/effectiveness-of-osteoporosis-drug-in-postmenopausal-women-with-spinal-compression-fracture-combined-consecutive-therapy-of-teriparatide-and-raloxifene-versus-bisphosphonate-single
#16
Chang Jin Shin, Sion Kim, Chun Sik Choi, Hyun Chul Shin, Young Joon Kwon
OBJECTIVE: Bisphosphonate, a typical bone resorption inhibitor, is an important first-line drug for treating osteoporosis. Recent studies show a novel paradigm in stimulating bone formation. Teriparatide, which is composed of recombinant human parathyroid hormone, stimulates osteoblasts and induces bone regeneration. Bone mineral density (BMD) that was used before and after the treatment with anti-osteoporosis drug was compared for the effectiveness in therapy between a combination of teriparatide and selective estrogen receptor modulator (SERM), and bisphosphonate...
October 2016: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/27854185/reduction-of-work-related-musculoskeletal-risk-factors-following-ergonomics-education-of-sewing-machine-operators
#17
Sıdıka Bulduk, Emre Özgür Bulduk, Tufan Süren
Work-related musculoskeletal disorders (WMSDs) are a major hazard for sewing machine operators. Ergonomics education is recommended for reducing musculoskeletal disorders at workstations. This study aimed to evaluate the effect of an ergonomics education in reducing the exposure to risk factors for WMSDs among sewing machine operators. In this study of 278 workers, their exposure to the risk of WMSDs was assessed using the quick exposure check (QEC) scale prior to them attending an ergonomics education programme and then again 3 months after the programme...
November 17, 2016: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/27836759/the-effect-of-single-nucleotide-polymorphisms-in-g-rich-regions-of-high-risk-human-papillomaviruses-on-structural-diversity-of-dna
#18
Maja Marušič, Lea Hošnjak, Petra Krafčikova, Mario Poljak, Viktor Viglasky, Janez Plavec
BACKGROUND: Infection with high-risk human papillomaviruses (HPVs) can lead to development of cancer of the head and neck and anogenital regions. G-rich sequences found in genomes of high-risk HPVs can fold into non-canonical secondary structures that could serve as 3D motifs distinct from double-stranded DNA and present recognition sites for ligands and opportunity for gene expression modulation. METHODS: Combination of UV, CD and NMR spectroscopy and PAGE electrophoresis were used as they offer complementary insights into structural changes of G-rich oligonucleotides...
November 9, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27830873/kinematic-mri-study-of-the-brain-stem-and-cervical-cord-by-dynamic-neck-motion
#19
Miloš Mališ, Biljana Georgievski, Ivan Milić, Aleksandar Mijatović, Vladan Kovačević, Dijana Lazić, Slobodan Kapor, Slobodan Marinkovic
BACKGROUND: The aim was to examine the position of the brain stem and cervical cord following the neck flexion and extension. MATERIALS AND METHODS: The serial sagittal T2-weighted MRI sections of the cervical cord and brain stem were made in 6 volunteers. The images were mainly used to measure certain distances and angles of the brain stem and cervical cord in the neutral position, and then following the head and neck flexion and extension. RESULTS: The measurements showed that the pons is slightly closer to the clivus following the neck flexion, the medulla oblongata is somewhat distant to the basion but closer to the odontoid process...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27823705/demonstration-of-sympathetic-dysfunction-in-patients-with-obstructive-sleep-apnea-syndrome-by-measuring-sympathetic-skin-responses-from-the-neck
#20
Bektaş Korkmaz, Gülçin Benbir Şenel, Meral E Kızıltan, Derya Karadeniz
OBJECTIVE: We aimed to study the sympathetic sudomotor responses via the sympathetic skin responses (SSR) from bilateral hands and right and left sides of the neck in patients with obstructive sleep apnea syndrome (OSAS). METHODS: A total of 31 patients with OSAS diagnosed by whole-night polysomnography and 18 healthy volunteers were consecutively enrolled into this prospective study. RESULTS: The SSRs from hands were not obtained in two patients with OSAS (6...
September 2016: Sleep Medicine
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