Siyu Lai, Dandan Yan, Jie Xu, Xiangtian Yu, Jingyi Guo, Xiangnan Fang, Mengyang Tang, Rong Zhang, Hong Zhang, Weiping Jia, Mingjuan Luo, Cheng Hu
AIM: To explore the genetic effects of CYP2C8, CYP2C9, CYP2J2, and EPHX2, the key genes involved in epoxyeicosatrienoic acid processing and degradation pathways in gestational diabetes mellitus (GDM) and metabolic traits in Chinese pregnant women. METHODS: A total of 2548 unrelated pregnant women were included, of which 938 had GDM and 1610 were considered as controls. Common variants were genotyped using the Infinium Asian Screening Array. Association studies of single nucleotide polymorphisms (SNPs) with GDM and related traits were performed using logistic regression and multivariable linear regression analyses...
June 28, 2023: Nutrition Journal