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https://www.readbyqxmd.com/read/27923269/what-must-be-done-to-prevent-another-humidifier-disinfectant-disaster
#1
Jong-Hyeon Lee
The humidifier disinfectant disaster (HDD) was not a simple poisoning accident by biocides, but a singular disaster in history created by chemicals in household products. This disaster was a result of the failure of a system for the management of chemical and product safety. Since the management authority for chemical usage safety is different from those for chemical safety in products, many blind areas for chemical safety management in products still remain. The 'Act on the Registration and Evaluation, etc...
2016: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/27923266/brief-practical-screeners-in-english-and-spanish-for-acute-posttraumatic-stress-symptoms-in-children
#2
Nancy Kassam-Adams, Meghan L Marsac
With millions of children experiencing acute traumatic events, validated screening tools are needed in both research and service contexts. We aimed to identify and evaluate short forms of the Acute Stress Checklist for Children in English (ASC-Kids) and Spanish (Cuestionario de Estrés Agudo-Niños [CEA-N]), using data from 4 samples (Ns of 254, 225, 176, and 80) of children with recent acute trauma. Confirmatory factor analyses of the full checklist in the largest sample guided item selection for 6-item and 3-item short forms...
December 2016: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/27923264/nationwide-access-to-an-internet-based-contingency-management-intervention-to-promote-smoking-cessation-a-randomized-controlled-trial
#3
Jesse Dallery, Bethany R Raiff, Sunny Jung Kim, Lisa A Marsch, Maxine Stitzer, Michael J Grabinski
BACKGROUND AND AIMS: Contingency management (CM) is one of the most effective behavioral interventions to promote drug abstinence, but availability of this treatment is limited. We evaluated the efficacy and acceptability of Internet-based CM relative to an Internet-based monitoring and goal setting control group in a nationwide sample of cigarette smokers. DESIGN: Randomized controlled trial with 3- and 6-month follow ups. SETTING: USA. PARTICIPANTS: Smokers (n = 94) from 26 states were enrolled (mean age 36, 56% female)...
December 6, 2016: Addiction
https://www.readbyqxmd.com/read/27923259/-established-therapies-and-new-therapeutic-strategies-in-alcoholic-liver-disease
#4
Helmut Karl Seitz, Sebastian Mueller
Chronical alcohol abuse causes more than 200 diseases and/or symptoms and among these alcoholic liver disease (ALD) is of special importance since it occurs frequently and may be life-threatening. In Europe alcohol consumption as well as ALD increased as compared to the rest of the world. It has been estimated that in Europe approximately 500 000 people die every year due to ALD. ALD consists of alcoholic fatty liver, alcoholic steatohepatitis (ASH), alcoholic cirrhosis and hepatocellar cancer (HCC ). Alcohol hepatitis (AH) is a clinical feature with jaundice and liver failure and a high mortality...
December 6, 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27923256/-fostering-resilience-while-waiting-for-psychotherapy-evaluation-of-a-group-intervention-in-an-outpatient-care-setting
#5
Philipp Victor, Tobias Teismann, Ulrike Willutzki
Background: High untreated prevalence of mental disorders and long waiting lists for psychotherapy at the same time call for innovative intervention concepts. The positive brief intervention "Personal Model of Resilience" 1 is offered as group training and evaluated for the first time in a naturalistic clinical setting. Method: In a pre-post-design data from 84 wait-list patients are analysed via intention-to-treat (n=84) and completer analysis at 6-week-follow-up (n=54). Results: Repeated measures ANOVAs demonstrate significant improvements in psychopathology, incongruence and self-esteem...
December 2016: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/27923255/-psychotherapy-and-religion-a-representative-survey-among-psychotherapists-in-southern-germany
#6
Michael Marquardt, Joachim Heinrich Demling
Objective: Religion and spirituality play an appreciable role as a problem area or as a resource for patients with mental disorders. It is therefore of interest what attitudes psychotherapists assume towards this complex range of issues in their work, but also in their personal lives. The majority of empirical studies on this subject originate from the USA, with little data being available from Europe and Germany. Our own survey among practising psychotherapists was designed to elucidate these questions. Method and Study Population: A cross-sectional study was conducted in the form of a written survey of all accessible practising psychotherapists in the area of Northern Bavaria (Franconian administrative districts; n=1 081, return rate 65%)...
December 2016: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/27923253/-personalization-instead-of-an-inflation-of-approaches-or-why-psychotherapy-research-should-and-can-be-expanded-in-germany-part-2
#7
Julian A Rubel, Wolfgang Lutz
No abstract text is available yet for this article.
December 2016: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/27923250/clinical-evaluation-of-the-first-automated-assay-for-the-detection-of-stimulating-tsh-receptor-autoantibodies
#8
S Allelein, M Ehlers, S Goretzki, D Hermsen, J Feldkamp, M Haase, T Dringenberg, C Schmid, H Hautzel, M Schott
Until recently, stimulating TSH receptor autoantibodies (sTRAbs) could only be measured by bioassays. A new assay system, which directly detects sTRAb in sera by applying bridge technology, has been established and is now available as automated chemiluminescence (bridge) immunoassay. We evaluated the automated bridge assay in clinical routine and compared it with a conventional automated TRAb assay (competition assay). Altogether, 226 Graves' disease (GD), 57 autoimmune thyroiditis, 74 non-autoimmune nodular goiter and 49 thyroid cancer patients, as well as 41 healthy controls were retrospectively evaluated...
December 2016: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/27923248/timing-of-multiorgan-dysfunction-among-hospitalized-infants-with-fatal-fulminant-sepsis
#9
James L Wynn, Matthew S Kelly, Daniel K Benjamin, Reese H Clark, Rachel Greenberg, Daniel K Benjamin, P Brian Smith
Objective Identify the progression of specific signs of multiorgan dysfunction among infants with fatal sepsis. Study Design Cohort study of 679 infants who died within 3 days of the start of a late-onset sepsis (LOS) episode in neonatal intensive care units from 1997 to 2012. We extracted clinical and laboratory data on the day of death (day 0) and the preceding 5 days (days -5 to -1). Results Median (25th percentile-75th percentile) gestational age was 25 (24-28) weeks. Compared with day -1, day 0 was characterized by an increased requirement for mechanical ventilation and higher mean fraction of inspired oxygen...
December 6, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27923243/-evaluation-of-contextual-factors-in-psychosomatic-rehabilitation
#10
N I Bülau, F Kessemeier, F Petermann, M Bassler, A Kobelt
Objectives: Although individualized and ICF-oriented implementation of rehabilitation treatment requires knowledge of relevant contextual factors, there is a lack of operationalized documentation and measurement tools to evaluate these factors. Therefore, an ICF-oriented semi-structured interview was designed. Methods: 20 contextual factors were externally assessed whether they negatively affected mental functioning and participation of psychosomatic patients. Additionally, psychometric scales were applied...
December 2016: Die Rehabilitation
https://www.readbyqxmd.com/read/27923240/-a-screening-tool-for-three-dimensions-of-work-related-behavior-and-experience-patterns-in-the-psychosomatic-rehabilitation-a-proposal-for-a-short-form-of-the-occupational-stress-and-coping-inventory-avem-3d
#11
V Beierlein, V Köllner, R Neu, H Schulz
Objectives: The assessment of work pressures is of particular importance in psychosomatic rehabilitation. An established questionnaire is the Occupational Stress and Coping Inventory (German abbr. AVEM), but it is quite long and with regard to scoring time-consuming in routine clinical care. It should therefore be tested, whether a shortened version of the AVEM can be developed, which is able to assess the formerly described three second-order factors of the AVEM, namely Working Commitment, Resilience, and Emotions, sufficiently reliable and valid, and which also may be used for screening of patients with prominent work-related behavior and experience patterns...
December 2016: Die Rehabilitation
https://www.readbyqxmd.com/read/27923235/association-of-the-cholinergic-muscarinic-m2-receptor-with-autonomic-nervous-system-activity-in-patients-with-schizophrenia-on-high-dose-antipsychotics
#12
Masatoshi Miyauchi, Ikuko Kishida, Akira Suda, Yohko Shiraishi, Saki Hattori, Mami Fujibayashi, Masataka Taguri, Chie Ishii, Norio Ishii, Toshio Moritani, Yoshio Hirayasu
BACKGROUND: Patients with schizophrenia have abnormal autonomic nervous system (ANS) activity compared with the general population. One reason for this difference is the muscarinic affinity for antipsychotic drugs; therefore, single nucleotide polymorphisms (SNPs) of the muscarinic receptor gene influence this ANS dysfunction. This study sought to determine the effect of SNPs of the cholinergic muscarinic receptor (CHRM) gene on ANS activity in patients with schizophrenia receiving antipsychotic drugs...
December 7, 2016: Neuropsychobiology
https://www.readbyqxmd.com/read/27923233/efficacy-of-adipodren%C3%A2-in-reducing-interleukin-1-induced-lymphatic-endothelial-hyperpermeability
#13
Valerio Ciccone, Martina Monti, Giulia Antonini, Luisa Mattoli, Michela Burico, Francesca Marini, Anna Maidecchi, Lucia Morbidelli
Lymphatic leakage can be seen as a detrimental phenomenon associated with fluid retention and deposition as well as gain of weight. Moreover, lymphatic dysfunction is associated with an inflammatory environment and can be a substrate for other health conditions. A number of treatments can ameliorate lymphatic vasculature: natural substances have been used as treatment options particularly suitable for their consolidated effectiveness and safety profile. Here we report the protective effect of AdipoDren®, an association of a series of plant-derived natural complexes, on lymphatic endothelium permeability promoted by interleukin-1 beta (IL-1β) and the associated molecular mechanisms...
December 7, 2016: Journal of Vascular Research
https://www.readbyqxmd.com/read/27923230/skull-subsidence-due-to-periosteum-defect-following-craniotomy-in-a-child
#14
Hidetaka Arishima, Ayumi Akazawa, Ken-Ichiro Kikuta
We report a case of a 7-year-old child with a cranial deformity secondary to a craniotomy for an intracranial hematoma. He suffered from an acute epidural hematoma with a lineal fracture of the right temporal bone following a severe head injury. A large question mark-shaped skin flap with the periosteum and temporal muscle was created for a decompressive craniectomy; however, neither the acute epidural hematoma nor brain swelling was severe, and we performed a small craniotomy compared with the skin flap without a decompressive craniectomy...
December 7, 2016: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27923229/hands-on-experience-accreditation-of-pathology-laboratories-according-to-iso-15189
#15
Alexandar Tzankov, Luigi Tornillo
Accreditation is a procedure by which an authoritative body gives formal recognition that an organization is competent to carry out specific tasks according to certain standards. Accreditation of pathology laboratories according to ISO 15189 is now becoming more and more a matter of course in continental Europe. This review describes some practical experience aspects with our own pathology laboratory accreditation according to ISO 15189, and outlines the advantages, addresses critical points, and discusses certain caveats of this process...
December 7, 2016: Pathobiology: Journal of Immunopathology, Molecular and Cellular Biology
https://www.readbyqxmd.com/read/27923228/feasibility-and-acceptability-of-anal-self-sampling-for-human-papillomavirus-screening-in-hiv-infected-patients
#16
Catherine Tamalet, Isabelle Ravaux, Catherine Dhiver, Amelie Menard, Philippe Colson, Andreas Stein
OBJECTIVES: Anal cancer incidence is increasing among HIV-positive patients. No consensus currently exists for the screening of anal dysplasia. This study aimed at evaluating the feasibility and acceptability of anal self-sampling and assessing the prevalence of human papillomavirus (HPV) types among HIV-positive patients from Marseille University Hospitals. METHODS: Between October 2013 and March 2014, during their regular visits for the monitoring of their HIV infection in an HIV outpatient clinical unit of Marseille University Hospitals, patients were asked to self-sample anal swabs for HPV detection...
December 7, 2016: Intervirology
https://www.readbyqxmd.com/read/27923227/optimal-role-of-the-nephrologist-in-the-intensive-care-unit
#17
D J Askenazi, Michael Heung, Michael J Connor, Rajit K Basu, Jorge Cerdá, Kent Doi, Jay L Koyner, Azra Bihorac, Ladan Golestaneh, Anitha Vijayan, Mark D Okusa, Sarah Faubel
As advances in Critical Care Medicine continue, critically ill patients are surviving despite the severity of their illness. The incidence of acute kidney injury (AKI) has increased, and its impact on clinical outcomes as well as medical expenditures has been established. The role, indications and technological advancements of renal replacement therapy (RRT) have evolved, allowing more effective therapies with less complications. With these changes, Critical Care Nephrology has become an established specialty, and ongoing collaborations between critical care physicians and nephrologist have improved education of multi-disciplinary team members and patient care in the ICU...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27923226/intraoperative-tumoral-bleeding-of-hypervascular-medulloblastoma-after-ventricular-drainage-a-case-report
#18
Han-Seung Ryu, Tae-Young Jung, Moon-Soo Han, Seul-Ki Kim, Kyung-Hwa Lee
We report a rare case of intraoperative tumoral bleeding of a hypervascular medulloblastoma. A 12-year-old girl presented with dizziness and nausea. Brain magnetic resonance (MR) images revealed an approximately 4.2-cm enhanced mass on the cerebellar vermis associated with mild perilesional edema and increased cerebral blood volume. Angiography showed tumoral staining and developed occipital and circular dural sinuses in the venous phase. A suboccipital craniotomy was performed. To relieve the intracranial pressure, cerebrospinal fluid (CSF) was drained via a lateral ventricular catheter in the occipital horn...
December 7, 2016: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27923225/integrin-%C3%AE-iib%C3%AE-3-dependent-erk-signaling-is-regulated-by-src-and-rho-kinases-in-both-leu33-and-pro33-polymorphic-isoforms
#19
Khon C Huynh, Thi-Hiep Nguyen, Dinh Chuong Pham, Huong T T Nguyen, Toi Van Vo, Marianna Gyenes, Volker R Stoldt
Platelet integrin αIIbβ3 possesses a Leu/Pro polymorphism at residue 33 (Leu33/HPA-1a or Pro33/HPA-1b). The Pro33 isoform has been suggested to exhibit prothrombotic features. αIIbβ3-expressing CHO (Chinese hamster ovary) cells on immobilized fibrinogen show activation of the MAP kinase family member ERK2, with an enhanced ERK2 activity in Pro33 cells compared to Leu33 cells. In our present work, we examined how the Leu/Pro polymorphism modulates the ERK2 activation stimulated by 2 differently triggered outside-in signalings...
December 7, 2016: Acta Haematologica
https://www.readbyqxmd.com/read/27923223/intestinal-pneumatosis-associated-with-tuberculosis-after-allogeneic-hematopoietic-stem-cell-transplantation
#20
Vivek Venkataramani, Ali Seif Amir Hosseini, Marco H Schulze, Lorenz Trümper, Gerald Wulf, Ulrike Bacher, Wolfram Jung
Pneumatosis intestinalis (PI), defined as intestinal intra- and extramural gas accumulation, is a rare radiographic finding in conditions of intestinal wall damage of varied etiology. Here, we report on a 56-year-old female with multiple myeloma who presented with undulating fever, fluctuating abdominal symptoms, and a distended abdomen 5 months after allogeneic hematopoietic stem cell transplantation (HSCT). Abdominal X-ray and CT scan documented PI with gas accumulation both in the intestinal and colonic bowel walls...
December 7, 2016: Acta Haematologica
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