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https://www.readbyqxmd.com/read/24734329/-a-coexistence-of-the-dupuytren-s-disease-and-malignant-neoplasms-a-review
#1
REVIEW
Andrzej Zyluk, Tadeusz Dibniak
Dupuytren's disease is classified as a benign superficial fibromatosis, in which excessive proliferation of myofibroblats and formation of nodules and chords occurs, followed by development of finger contractures. The similarities between Dupuytren's disease and neoplasms were shown at molecular and clinical grounds. The objective of the study was to review of the literature investigating possible relationship between occurrence of Dupuytren's disease and malignancies. Review of the few available papers shows (1) statistically significantly increased malignant neoplasm mortality among men with advanced Dupuytren's disease, comparing to reference population and men with early stage of the disease, (2) statistically significantly increased malignant neoplasm morbidity, mainly related to smoking and alcohol consumption among patients (men and women) operated on for Dupuytren's disease and (3) increased sarcoma of the bone and soft tissue morbidity in patients 5 years after operation for Dupuytren's disease...
2013: Annales Academiae Medicae Stetinensis
https://www.readbyqxmd.com/read/23303836/common-variants-of-the-aldh2-and-dhdh-genes-and-the-risk-of-dupuytren-s-disease
#2
A Zyluk, T Debniak, P Puchalski
The object of this study was the investigation of four common variants of single nucleotide polymorphisms of the aldehyde dehydrogenase H2 gene and dihydrodiol dehydrogenase gene and their association with the occurrence of Dupuytren's disease. DNA samples were obtained from the peripheral blood of 300 consecutive patients. The control group comprised 300 healthy adults who were age matched with the Dupuytren's patients. All four common variants were analysed using TaqMan® genotyping assays and sequencing...
May 2013: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/23028369/a-comparison-of-brain-gene-expression-levels-in-domesticated-and-wild-animals
#3
Frank W Albert, Mehmet Somel, Miguel Carneiro, Ayinuer Aximu-Petri, Michel Halbwax, Olaf Thalmann, Jose A Blanco-Aguiar, Irina Z Plyusnina, Lyudmila Trut, Rafael Villafuerte, Nuno Ferrand, Sylvia Kaiser, Per Jensen, Svante Pääbo
Domestication has led to similar changes in morphology and behavior in several animal species, raising the question whether similarities between different domestication events also exist at the molecular level. We used mRNA sequencing to analyze genome-wide gene expression patterns in brain frontal cortex in three pairs of domesticated and wild species (dogs and wolves, pigs and wild boars, and domesticated and wild rabbits). We compared the expression differences with those between domesticated guinea pigs and a distant wild relative (Cavia aperea) as well as between two lines of rats selected for tameness or aggression towards humans...
September 2012: PLoS Genetics
https://www.readbyqxmd.com/read/18836565/genes-on-bovine-chromosome-18-associated-with-bilateral-convergent-strabismus-with-exophthalmos-in-german-brown-cattle
#4
S Fink, S Mömke, A Wöhlke, O Distl
PURPOSE: Bilateral convergent strabismus with exophthalmos (BCSE) is a widespread inherited eye defect in several cattle populations. Its progressive condition often leads to blindness in affected cattle and shortens their length of productive life. Furthermore, breeding with BCSE-affected animals is forbidden by the German animal welfare laws. We performed a mutation and association analysis for three candidate genes (troponin T type 1 [TNNT1], retinol dehydrogenase 13 [RDH13], and TCF3 fusion partner [TFPT]), which are located within the previously identified BCSE-linked region on the telomeric end of bovine chromosome 18 (BTA18)...
2008: Molecular Vision
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