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https://www.readbyqxmd.com/read/29155760/echocardiographic-and-histological-examination-of-cardiac-morphology-in-the-mouse
#1
Delphine Baudouy, Jean-François Michiels, Ana Vukolic, Kay-Dietrich Wagner, Nicole Wagner
An increasing number of genetically modified mouse models has become available in recent years. Moreover, the number of pharmacological studies performed in mice is high. Phenotypic characterization of these mouse models also requires the examination of cardiac function and morphology. Echocardiography and magnetic resonance imaging (MRI) are commonly used approaches to characterize cardiac function and morphology in mice. Echocardiographic and MRI equipment specialized for use in small rodents is expensive and requires a dedicated space...
October 26, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29119598/opening-closing-pattern-of-trifecta-and-freestyle-valves-versus-native-aortic-valve-are-stentless-valves-more-physiologic-than-a-stented-valve
#2
Giordano Tasca, Riccardo Vismara, Francesco Trinca, Beatrice Riva, Amando Gamba, Elisabetta Lobiati
BACKGROUND: Stentless valves have long been considered the ideal valves in terms of hemodynamics. Recently, the Trifecta valve, a stented bioprosthesis with excellent fluid dynamic characteristics, has become available. The aim of the study was to compare the opening/closing pattern of the Freestyle stentless valve and the Trifecta valve with that of the native aortic valve. METHODS: A total of 12 patients with a Freestyle and 10 with a Trifecta valve were compared to normal native aortic valves in 12 control patients...
November 9, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29118885/mitral-annular-dynamics-and-left-ventricular-diastole
#3
Angel Lopez-Candales, Dagmar F Hernandez-Suarez, Francisco Lopez Menendez
Background: Though diastolic interrogation of the mitral annulus (MA) using tissue Doppler imaging (TDI) has been quite useful in assessing left ventricular (LV) diastolic function, the relative contribution of the previous cycle MA systolic displacement or velocity components to subsequent LV diastole has not been previously investigated. We therefore sought to determine the association between MA systolic dynamics and LV diastolic function parameters. Methods: For this retrospective study, only complete echocardiograms having good endocardial border resolution of both left atrial (LA) and LV chambers with M-mode (MAPSE) and tissue Doppler of the lateral MA (MA TDI S') as well as complete Doppler data to perform assessment of LV diastole were included in our analysis...
October 2017: Cardiology Research
https://www.readbyqxmd.com/read/29116970/assessment-of-tricuspid-annular-motion-by-speckle-tracking-in-anesthetized-patients-using-transesophageal-echocardiography
#4
Tao Shen, Michael H Picard, Lanqi Hua, Sara M Burns, Michael N Andrawes
BACKGROUND: The perioperative assessment of right ventricular (RV) function remains a challenge. Tricuspid annular plane systolic excursion (TAPSE) using M-mode is a widely used measure of RV function. However, accurate alignment of the ultrasound beam with the direction of annular movement can be difficult with transesophageal echocardiography (TEE) to measure TAPSE, precluding effective use of M-mode to measure annular excursion. Tracking of specular reflectors in the myocardium may provide an angle-independent method to assess annular motion with TEE...
November 7, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29115392/the-inhibition-of-myd88-and-trif-signaling-serve-equivalent-roles-in-attenuating-myocardial-deterioration-due-to-acute-severe-inflammation
#5
Min-Zhi Ouyang, Dan Zhou, Yun Zhu, Ming Zhang, Ling Li
Myeloid differentiation factor 88 (MyD88) and Toll or interleukin-1 receptor-domain-containing adaptor-inducing interferon-β (IFN-β) (TRIF) are two pivotal downstream adaptors of Toll-like receptors. Activation of MyD88 or TRIF signaling in cardiac immune pathology of severe inflammation negatively influences heart function. In the present study, severe septic cardiac injury was induced in C57BL/6 mice by cecum ligation and puncture (CLP). A total of 64 mice were divided randomly into the following four groups (n=16/group; 8 for observation of survival rate, 8 for heart sample analysis): Sham, CLP, anti-MyD88-CLP and anti-TRIF-CLP...
November 7, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29111423/maternal-cardiovascular-dysfunction-in-women-with-early-onset-preeclampsia-and-late-onset-preeclampsia-a-cross-sectional-study
#6
Sindhura Vaddamani, Anish Keepanasseril, Ajith Ananthakrishna Pillai, Binay Kumar
OBJECTIVES: To compare the cardiovascular changes associated with early onset (EOPE) and late onset (LOPE) subtypes of preeclampsia. METHODS: A prospective matched cross-sectional study involving 50 women each with early and late onset subtypes of preeclampsia conducted in a tertiary hospital in South India. Cardiac function and remodelling were assessed by conventional 2D, M-mode and doppler echocardiography. RESULTS: Women with EOPE had a significantly more altered left ventricular (LV) geometry, global LV diastolic dysfunction, impairment in myocardial contractility (40% vs...
October 25, 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29111285/reference-values-of-two-dimensional-and-m-mode-echocardiographic-measurements-as-a-function-of-body-size-in-various-equine-breeds-and-in-ponies
#7
A Al-Haidar, N Moula, A Leroux, F Farnir, S Deleuze, C Sandersen, H Amory
INTRODUCTION: The aim of this study was to establish echocardiographic reference values for the equine species using allometric regression equations based on body weight (BW) and thoracic circumference (TC). ANIMALS: A total of 239 horses or ponies were studied, including 65 warmbloods, 33 Standardbreds, 41 Thoroughbreds, 32 Arabian horses, 28 draft horses, and 40 ponies aged from 1 day to 30 years, weighing from 18 to 890 kg, with no evidence of cardiac disease...
October 27, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/29110750/aortic-elasticity-and-carotid-intima-media-thickness-in-children-with-mitral-valve-prolapse
#8
Elif Erolu, Figen Akalın, Nilüfer Çetiner, Berna Şaylan Çevik
Aim We aimed to study the dimensions, systolic and diastolic functions of the left ventricle; dimensions and elasticity of the aorta; and carotid intima-media thickness and flow-mediated dilatation of the brachial artery in mitral valve prolapse. METHODS: The study group consisted of 43 patients (mean age=13.3±3.9) and 42 healthy children (mean age=12.9±3.4). Left ventricular end-diastolic, end-systolic, left atrial diameters, interventricular septum, and left ventricular posterior wall thickness were measured...
November 7, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29110304/beta-blockers-for-preventing-aortic-dissection-in-marfan-syndrome
#9
REVIEW
Hyun-Kyoung Koo, Kendra Ak Lawrence, Vijaya M Musini
BACKGROUND: Marfan syndrome is a hereditary disorder affecting the connective tissue and is caused by a mutation of the fibrillin-1 (FBN1) gene. It affects multiple systems of the body, most notably the cardiovascular, ocular, skeletal, dural and pulmonary systems. Aortic root dilatation is the most frequent cardiovascular manifestation and its complications, including aortic regurgitation, dissection and rupture are the main cause of morbidity and mortality. OBJECTIVES: To assess the long-term efficacy and safety of beta-blocker therapy as compared to placebo, no treatment or surveillance only in people with Marfan syndrome...
November 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29106902/the-use-of-m-mode-ultrasonography-to-differentiate-the-etiology-of-b-lines
#10
Anup K Singh, Paul H Mayo, Seth Koenig, Aranabh Talwar, Mangala Narasimhan
BACKGROUND: The presence of B lines on lung ultrasonography is a characteristic feature of both cardiogenic pulmonary edema (CPE) and non cardiogenic alveolar interstitial syndrome (NCAIS), so their presence does not allow the clinician to differentiate between the two entities. Our study uses M mode ultrasonography of the pleura to differentiate cardiogenic pulmonary edema vs. non cardiogenic alveolar interstitial syndrome. METHODS: A total of 43 subjects were enrolled in the study and based upon history, physical examination, and chart review the patients were divided into three groups...
October 26, 2017: Chest
https://www.readbyqxmd.com/read/29083326/aortic-propagation-velocity-does-not-correlate-with-classical-aortic-stiffness-parameters-in-healthy-individuals
#11
Hatem Arı, Fatih Kahraman, Yasin Türker, Serdar Güler, Hasan Aydın Baş, Doğan Erdoğan
OBJECTIVE: Aortic stiffness is an important cardiovascular risk marker, which can be determined using different noninvasive techniques. Aortic propagation velocity (APV) has recently been established as a novel echocardiographic parameter of aortic stiffness. This study aimed to investigate the association between APV and the classical echocardiography-derived aortic stiffness parameters, aortic distensibility (AD) and aortic strain (AS), in a group of otherwise healthy individuals. METHODS: In total, 97 consecutive healthy subjects were recruited in this observational study...
October 30, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29072062/morpho-functional-cardiovascular-adaptation-in-hypertensive-patients-two-dimensional-speckle-tracking-echocardiographic-study
#12
Ines P Monte, Chiara DI Benedetto, Filippo A Atanasio, Valentina Losi, Salvatore Licciardi, Corrado Tamburino
BACKGROUND: Twenty-four-hour Blood Pressure (BP) variability is an important predictor of organ damage and cardiovascular events. Although epidemiological data are widely based on evaluation of office (Clinic) BP, 24-hour Ambulatory BP monitoring (ABPM) accurately assess the severity of hypertension to predict cardiovascular events in hypertensive patients, because it more accurately reflects BP load on heart and blood vessels. Conventional transthoracic echocardiography (TTE), such as M-mode and two-dimensional (2D), and more advanced techniques, such as tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE), are used to identify pathological changes of the hypertensive heart disease...
October 25, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29061725/relationship-between-24-hour-ambulatory-central-systolic-blood-pressure-and-left-ventricular-mass-a-prospective-multicenter-study
#13
Thomas Weber, Siegfried Wassertheurer, Arno Schmidt-Trucksäss, Enrique Rodilla, Cornelia Ablasser, Piotr Jankowski, Maria Lorenza Muiesan, Cristina Giannattasio, Claudia Mang, Ian Wilkinson, Jörg Kellermair, Bernhard Hametner, Jose Maria Pascual, Robert Zweiker, Danuta Czarnecka, Anna Paini, Massimo Salvetti, Alessandro Maloberti, Carmel McEniery
We investigated the relationship between left ventricular mass and brachial office as well as brachial and central ambulatory systolic blood pressure in 7 European centers. Central systolic pressure was measured with a validated oscillometric device, using a transfer function, and mean/diastolic pressure calibration. M-mode images were obtained by echocardiography, and left ventricular mass was determined by one single reader blinded to blood pressure. We studied 289 participants (137 women) free from antihypertensive drugs (mean age: 50...
October 23, 2017: Hypertension
https://www.readbyqxmd.com/read/29029085/impairment-of-elastic-properties-of-the-aorta-in-bicuspid-aortic-valve-relationship-between-biomolecular-and-aortic-strain-patterns
#14
Luca Longobardo, Maria Ludovica Carerj, Gabriele Pizzino, Alessandra Bitto, Maurizio Cusma Piccione, Marta Zucco, Lilia Oreto, Maria Chiara Todaro, Maria Pia Calabrò, Francesco Squadrito, Gianluca Di Bella, Giuseppe Oreto, Bijoy K Khandheria, Scipione Carerj, Concetta Zito
Aims: Bicuspid aortic valve (BAV) is associated with aortic wall alterations. We aimed to detect any correlation between aortic elasticity and genetic and biomolecular patterns of elastin. Methods and results: Forty-nine BAV patients (mean age: 38 ± 17.05) were prospectively enrolled. A blood sample was drawn for analysis of a single nucleotide polymorphism of elastin gene (ELN rs2071307) responsible for misfolding of elastin, and for the amount of elastin soluble fragments (ESF) in the plasma...
September 23, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29021922/texture-feature-variability-in-ultrasound-video-of-the-atherosclerotic-carotid-plaque
#15
Christos P Loizou, Constantinos S Pattichis, Marios Pantziaris, Efthyvoulos Kyriacou, Andrew Nicolaides
The objective of this paper was to investigate texture feature variability in ultrasound video of the carotid artery during the cardiac cycle in an attempt to define new discriminatory biomarkers of the vulnerable plaque. More specifically, in this paper, 120 longitudinal ultrasound videos, acquired from 40 normal (N) subjects from the common carotid artery and 40 asymptomatic (A) and 40 symptomatic (S) subjects from the proximal internal carotid artery were investigated. The videos were intensity normalized and despeckled, and the intima-media complex (IMC) (from the N subjects) and the atherosclerotic carotid plaques (from the A and S subjects) were segmented from each video, in order to extract the M-mode image, and the texture features associated with cardiac states of systole and diastole...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/29021847/a-new-mapping-method-to-estimate-exit-sites-of-ventricular-arrhythmias-using-intracardiac-echocardiography-and-m-mode-for-catheter-ablation
#16
Osamu Inaba, Junichi Nitta, Syunsuke Kuroda, Masahiro Sekigawa, Masahito Suzuki, Yukihiro Inamura, Akira Satoh, Mitsuaki Isobe, Kenzo Hirao
BACKGROUND: Catheter ablation of premature ventricular complexes (PVCs) has been used as a curative therapy in many cases. Intracardiac ultrasound with a magnetic sensor probe has recently become available for catheter ablation. In this study, we assessed a new mapping method, contraction mapping, for determining the optimal ablation sites using intracardiac ultrasound and M-mode. This study sought to assess the accuracy of the new mapping method using intracardiac echocardiography. METHODS: Eighteen patients (10 males and eight females; mean age, 63±12 years) with 104 mapping points diagnosed as idiopathic PVCs were included in this study...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29019716/subclinical-impairment-of-the-left-ventricular-longitudinal-function-in-patients-with-prolactinomas
#17
Xiao-Bing Jiang, Jing Zhang, Cui-Ling Li, Zhi-Gang Mao, Bin Hu, Zhe Zhu, Yong-Hong Zhu, Hai-Jun Wang
Purpose Hyperprolactinemia has been associated with endothelial dysfunction and a wide range of cardiovascular risk factors, thus it can potentially lead to cardiac dysfunction. The present study was designed to interrogate our hypothesis that hyperprolactinemia can contribute to preclinical impaired left ventricular function. Patients and Methods Thirty-one prolactinoma patients and sixty healthy volunteers were prospectively recruited. Left ventricular function was evaluated using conventional two dimensions and M-mode echocardiography, as well as Doppler tissues imaging (DTI)...
October 11, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28983169/left-atrium-in-cardiac-resynchronization-therapy-active-participant-or-innocent-bystander
#18
Haitham A Badran, M A Abdelhamid, Mazen T Ibrahim, Ayman M Abdelmoteleb, John K Zarif
BACKGROUND: Cardiac resynchronization therapy (CRT) is an established treatment for patients with advanced heart failure that results in improvement of left ventricle (LV) systolic function and LV reverse remodeling. This may have a positive effect on the size and the function of the left atrium (LA). We assessed the LA function, dimensions, and volumes before and after CRT implantation. METHODS: A total of 37 patients with mean age of 55.3 ± 9.64 years including 11 (29...
October 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28983167/predictors-of-transient-left-ventricular-dysfunction-following-transcatheter-patent-ductus-arteriosus-closure-in-pediatric-age
#19
Hala Mounir Agha, Hala S Hamza, Alyaa Kotby, Mona E L Ganzoury, Nanies Soliman
OBJECTIVES: To evaluate the left ventricular function before and after transcatheter percutaneous patent ductus arteriosus (PDA) closure, and to identify the predictors of myocardial dysfunction post-PDA closure if present. INTERVENTIONS: Transcatheter PDA closure; conventional, Doppler, and tissue Doppler imaging; and speckle tracking echocardiography. OUTCOME MEASURES: To determine the feasibility and reliability of tissue Doppler and myocardial deformation imaging for evaluating myocardial function in children undergoing transcatheter PDA closure...
October 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28982329/high-resolution-m-mode-evaluation-of-jugular-vein-valves-in-patients-with-neurological-and-neurosensory-disorders
#20
E Menegatti, M Tessari, M E Vannini, S Gianesini, A M Malagoni, A Ciorba, M Mazzoli, F Sisini, F Salvi, S Pelucchi, P Zamboni
BACKGROUND: High prevalence of valve absence was found in the internal jugular vein (IJV) of healthy volunteers by means of M-mode high-resolution echo colour Doppler (ECD). However, the prevalence of valve in neurovascular disorders linked to chronic cerebrospinal venous insufficiency (CCSVI) is still unknown. METHODS: A cohort of 83 healthy controls (HC), 71 multiple sclerosis (MS), 99 Inner Ear Disorders (IED) underwent ECD investigation of the IJV valve, including M-mode evaluation and related haemodynamics...
October 5, 2017: Current Neurovascular Research
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