M Pérez Sirvent, I Moreno Miralles, P Boluferx Gilabert, E Lerma Alejos, M A Gómez Rejas, A Vayá Montaña, A Tascón Astigarraga, M A Dasí Carpio, M Martínez Silvestre, A R López Espinosa, L Hernández Mateo, R Gil Alfonso
PURPOSE: The aim of the study is to present the first results of molecular characterization of thalassaemias in Valencian Community and their relationship with the haematological parameters. PATIENTS AND METHODS: The study includes 87 thalassemic patients: 30 alpha-thalassaemias, 40 beta-thalassaemias and 17 delta beta-thalassaemias. The molecular alterations were studied in white cell blood DNA, either following different PCR methods or by testing the digestion of the amplified PCR products with selective restriction enzymes...
October 1998: Sangre