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https://www.readbyqxmd.com/read/28346899/multi-scale-approach-to-euro-atlantic-climatic-cycles-based-on-phenological-time-series-air-temperatures-and-circulation-indexes
#1
Luigi Mariani, Franco Zavatti
The spectral periods in North Atlantic Oscillation (NAO), Atlantic Multidecadal Oscillation (AMO) and El Nino Southern Oscillation (ENSO) were analyzed and has been verified how they imprint a time series of European temperature anomalies (ETA), two European temperature time series and some phenological series (dates of cherry flowering and grapevine harvest). Such work had as reference scenario the linear causal chain MCTP (Macroscale Circulation→Temperature→Phenology of crops) that links oceanic and atmospheric circulation to surface air temperature which in its turn determines the earliness of appearance of phenological phases of plants...
March 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28346860/comparison-of-short-term-effects-of-diquafosol-and-rebamipide-on-mucin-5ac-level-on-the-rabbit-ocular-surface
#2
Yuichi Hori, Tomofumi Kageyama, Asuka Sakamoto, Tomoaki Shiba, Masatsugu Nakamura, Takatoshi Maeno
PURPOSE: To investigate the short-term effects of 2 new secretagogue eye drops for dry eye, 3% diquafosol tetrasodium ophthalmic solution (diquafosol) and 2% rebamipide ophthalmic suspension (rebamipide), on the concentration of mucin 5AC (MUC5AC) in rabbit tear fluid and conjunctival goblet cells. METHODS: One dose of artificial tears, diquafosol or rebamipide, was instilled into 8 eyes of Japanese white rabbits. MUC5AC concentration in the tear fluid was examined using the enzyme-linked immunosorbent assay 15 min after instillation and compared with 8 untreated controls...
March 27, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28346851/aquatic-therapy-for-people-with-lymphedema-a-systematic-review-and-meta-analysis
#3
Wai Yeung, Adam I Semciw
BACKGROUND: Aquatic therapy has several proposed benefits for people with lymphedema. A systematic review of the evidence for aquatic therapy in lymphedema management has not been conducted. METHOD AND RESULTS: Systematic review and meta-analysis were conducted. Five electronic databases were searched to identify randomized controlled trials (RCTs) of people with lymphedema, which compared aquatic therapy with other lymphedema interventions. Qualitative analysis was undertaken where quantitative analysis was not possible...
March 27, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28346845/commentary-on-kang-et-al-single-port-laparoscopic-surgery-can-be-performed-safely-and-appropriately-for-colon-cancer-short-term-results-of-a-pilot-randomized-controlled-trial
#4
Samuel Eisenstein
No abstract text is available yet for this article.
March 27, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28346765/the-medial-temporal-memory-system-in-down-syndrome-translating-animal-models-of-hippocampal-compromise
#5
Caron A C Clark, Fabian Fernandez, Stella Sakhon, Goffredina Spanò, Jamie O Edgin
Recent studies have highlighted the dentate gyrus as a region of increased vulnerability in mouse models of Down syndrome (DS). It is unclear to what extent these findings are reflected in the memory profile of people with the condition. We developed a series of novel tasks to probe distinct medial temporal functions in children and young adults with DS, including object, spatial, and serial order memory. Relative to mental age-matched controls (n = 45), individuals with DS (n = 28) were unimpaired on subtests involving short-term object or configural recall that was divorced from spatial or temporal contexts...
March 27, 2017: Hippocampus
https://www.readbyqxmd.com/read/28346724/acclimation-of-bloom-forming-and-perennial-seaweeds-to-elevated-pco2-conserved-across-levels-of-environmental-complexity
#6
Dong Xu, C-Elisa Schaum, Fan Lin, Ke Sun, James R Munroe, Xiao W Zhang, Xiao Fan, Lin H Teng, Yi T Wang, Zhi Z Zhuang, Nai H Ye
Macroalgae contribute approximately 15% of the primary productivity in coastal marine ecosystems, fix up to 27.4 Tg of carbon per year, and provide important structural components for life in coastal waters. Despite this ecological and commercial importance, direct measurements and comparisons of the short-term responses to elevated pCO2 in seaweeds with different life-history strategies are scarce. Here, we cultured several seaweed species (bloom-forming/non-bloom-forming/perennial/annual) in the laboratory, in tanks in an in-door mesocosm facility, and in coastal mesocosms under pCO2 levels ranging from 400 μatm to 2000 μatm...
March 27, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28346394/engineered-resistant-starch-ers-diet-shapes-colon-microbiota-profile-in-parallel-with-the-retardation-of-tumor-growth-in-in-vitro-and-in-vivo-pancreatic-cancer-models
#7
Concetta Panebianco, Kaarel Adamberg, Signe Adamberg, Chiara Saracino, Madis Jaagura, Kaia Kolk, Anna Grazia Di Chio, Paolo Graziano, Raivo Vilu, Valerio Pazienza
BACKGROUND/AIMS: Pancreatic cancer (PC) is ranked as the fourth leading cause of cancer-related deaths worldwide. Despite recent advances in treatment options, a modest impact on the outcome of the disease is observed so far. We have previously demonstrated that short-term fasting cycles have the potential to improve the efficacy of chemotherapy against PC. The aim of this study was to assess the effect of an engineered resistant-starch (ERS) mimicking diet on the growth of cancer cell lines in vitro, on the composition of fecal microbiota, and on tumor growth in an in vivo pancreatic cancer mouse xenograft model...
March 27, 2017: Nutrients
https://www.readbyqxmd.com/read/28345961/the-short-term-efficacy-of-an-unguided-internet-based-cognitive-behavioral-therapy-for-insomnia-a-randomized-controlled-trial-with-a-six-month-nonrandomized-follow-up
#8
Susanne Hagatun, Øystein Vedaa, Tine Nordgreen, Otto R F Smith, Ståle Pallesen, Odd E Havik, Bjørn Bjorvatn, Frances P Thorndike, Lee M Ritterband, Børge Sivertsen
OBJECTIVE: Insomnia is a major health problem, and the need for effective and accessible treatment is urgent. The aim of the current study was to evaluate the short-term efficacy of an unguided Internet-based cognitive-behavioral treatment program for insomnia (CBTi), called SHUTi (Sleep Healthy Using the Internet). METHODS: This study used a parallel arm randomized controlled trial in Norway. Participants were randomly allocated to the SHUTi condition or a Web-based patient education condition...
March 27, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28345896/transcriptomics-and-lipidomics-of-the-environmental-strain-rhodococcus-ruber-point-out-consumption-pathways-and-potential-metabolic-bottlenecks-for-polyethylene-degradation
#9
Kevin Gravouil, Romain Ferru-Clement, Steven Colas, Reynald Helye, Linette Kadri, Ludivine Bourdeau, Bouziane Moumen, Anne Mercier, Thierry Ferreira
Polyethylene (PE), one of the most prominent synthetic polymer used worldwide, is very poorly biodegradable in the natural environment. Consequently, PE represents by itself more than half of all plastic wastes. PE biodegradation is achieved through the combination of abiotic and biotic processes. Several microorganisms have been shown to grow on the surface of PE materials, among which are the species of the Rhodococcus genus, suggesting a potent ability of these microorganisms to use, at least partly, PE as a potent carbon source...
March 27, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28345890/relationship-of-microbiota-and-cyanobacterial-secondary-metabolites-in-planktothricoides-dominated-bloom
#10
Shu Harn Te, Boon Fei Tan, Janelle Renee Thompson, Karina Yew-Hoong Gin
Identification of phytoplankton species and microbial biodiversity is necessary to assess water ecosystem health and the quality of water resources. We investigated the short-term (2 days) vertical and diel variations in bacterial community structure and microbially-derived secondary metabolites during a cyanobacterial bloom that emerged in a highly urbanized tropical reservoir. The waterbody was largely dominated by the cyanobacteria Planktothricoides spp., together with the Synechococcus, Pseudanabaena, Prochlorothrix and Limnothrix...
March 27, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28345762/short-term-effects-of-low-carbohydrate-diet-on-glycaemic-parameters-and-cardiovascular-risk-markers-in-patients-with-type-1-diabetes-a-randomised-open-label-cross-over-trial
#11
A Ranjan, S Schmidt, C Damm-Frydenberg, J Holst, S Madsbad, K Nørgaard
The objective was to compare effects of high carbohydrate diet (HCD) versus low carbohydrate diet (LCD) on glycaemic parameters and cardiovascular risk markers in patients with type 1 diabetes. Ten patients (4 women, insulin pump-treated, median±SD age: 48 ± 10 years, HbA1c: 53 ± 6 mmol/mol (7.0 ± 0.6%)) followed one week of isocaloric HCD (≥250 g/day) and one week of isocaloric LCD (≤50 g/day) in random order. After each week, we downloaded pump and sensor data and collected fasting blood and urine samples...
March 27, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28345620/acute-and-chronic-mitochondrial-respiratory-chain-deficiency-differentially-regulate-lysosomal-biogenesis
#12
Lorena Fernández-Mosquera, Cátia V Diogo, King Faisal Yambire, Gabriela L Santos, Marta Luna Sánchez, Paule Bénit, Pierre Rustin, Luis Carlos Lopez, Ira Milosevic, Nuno Raimundo
Mitochondria are key cellular signaling platforms, affecting fundamental processes such as cell proliferation, differentiation and death. However, it remains unclear how mitochondrial signaling affects other organelles, particularly lysosomes. Here, we demonstrate that mitochondrial respiratory chain (RC) impairments elicit a stress signaling pathway that regulates lysosomal biogenesis via the microphtalmia transcription factor family. Interestingly, the effect of mitochondrial stress over lysosomal biogenesis depends on the timeframe of the stress elicited: while RC inhibition with rotenone or uncoupling with CCCP initially triggers lysosomal biogenesis, the effect peaks after few hours and returns to baseline...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28345520/-management-of-patients-with-bradykinin-mediated-angioedema-in-oral-and-maxillofacial-surgery
#13
J Rohart, L Bouillet, H Moizan
Bradykinin-mediated angioedema (AE) is a rare disease characterized by recurrent cutaneous or mucosal angioedema. This hereditary or acquired disease is of rapid installation, non-pruritic, usually painless and can affect the face, lips, larynx, gastrointestinal tract or extremities. When the affected area involves the upper respiratory tract, laryngeal angioedema can lead to imminent death by asphyxia. This is the reason for the high mortality rate (30 %) in undiagnosed or improperly managed patients. High-risk situations in oral and maxillofacial surgery procedures should be identified preoperatively...
February 22, 2017: J Stomatol Oral Maxillofac Surg
https://www.readbyqxmd.com/read/28345481/cost-effectiveness-analysis-of-implementing-an-antimicrobial-stewardship-programme-in-critical-care-units
#14
Jesus Ruiz-Ramos, Juan Frasquet, Eva Romá, Jose Luis Poveda-Andres, Miguel Salavert-Leti, Alvaro Catellanos, Paula Ramirez
AIMS: To evaluate the cost-effectiveness of antimicrobial stewardship (AS) programme implementation focused on critical care units based on assumptions for the Spanish setting. MATERIAL AND METHODS: A decision model comparing costs and outcomes of sepsis, community-acquired pneumonia, and nosocomial infections (including catheter-related bacteremia, urinary tract infection, and ventilator-associated pneumonia) in critical care units with or without an AS was designed...
March 26, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28345442/predicting-1-year-statin-adherence-among-prevalent-users-a-retrospective-cohort-study
#15
Alexis A Krumme, Jessica M Franklin, Danielle L Isaman, Olga S Matlin, Angela Y Tong, Claire M Spettell, Troyen A Brennan, William H Shrank, Niteesh K Choudhry
BACKGROUND: Attempts to predict who is at risk of future nonadherence have largely focused on predictions at the time of therapy initiation; however, these users are only a small proportion of all patients on therapy at any point in time. Methods to predict nonadherence for established medication users, which have not been previously described in the literature, would be helpful to guide efforts to enhance the use of evidence-based therapies. OBJECTIVE: To test approaches for adherence prediction among prevalent statin users, namely the use of short-term filling behavior, investigator-specified predictors from medical and pharmacy administrative claims, and the empirical selection of potential predictors using the high-dimensional propensity score variable selection algorithm...
April 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28345364/anatomically-contoured-anterior-plating-for-isolated-tibiotalar-arthrodesis
#16
Nicholas Kusnezov, John C Dunn, Logan R Koehler, Justin D Orr
INTRODUCTION: We performed a systematic review of the published literature to characterize patient demographic, surgical techniques, and functional outcomes to elucidate the complication and revision rates following isolated tibiotalar arthrodesis with anatomically contoured anterior plating. METHODS: A comprehensive literature search was performed. Inclusion criteria were peer-reviewed studies in English, after 1990, at least 10 patients, and reporting clinical outcomes following contoured anterior plating and with follow-up of at least 80% and 1 year...
March 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28345299/a-prospective-study-of-health-related-quality-of-life-of-boys-with-severe-haemophilia-a-in-china-comparing-on-demand-to-prophylaxis-treatment
#17
R Wu, J Sun, J Xiao, Y Liu, F Xue, H Wang, L Tang, Y Zhao, K Li, R Yang, Y Hu, K-H Luke, M-C Poon, V S Blanchette, K Usuba, N L Young
INTRODUCTION: Treatment for boys with haemophilia in China is rapidly improving; however, comprehensive outcomes have not been examined prospectively. AIM: The aim of this study was to evaluate the effect of short-term full-dose prophylaxis compared to on-demand treatment, on the Health-Related Quality of Life (HR-QoL) of boys with severe haemophilia A (HA) in China. METHODS: Boys with severe HA (FVIII<1%) completed 3 months of on-demand treatment and 3 months of full-dose prophylaxis (25 FVIII IU per kg 3x per week)...
March 27, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28345272/population-health-and-the-economy-mortality-and-the-great-recession-in-europe
#18
José A Tapia Granados, Edward L Ionides
We analyze the evolution of mortality-based health indicators in 27 European countries before and after the start of the Great Recession. We find that in the countries where the crisis has been particularly severe, mortality reductions in 2007-2010 were considerably bigger than in 2004-2007. Panel models adjusted for space-invariant and time-invariant factors show that an increase of 1 percentage point in the national unemployment rate is associated with a reduction of 0.5% (p < .001) in the rate of age-adjusted mortality...
March 27, 2017: Health Economics
https://www.readbyqxmd.com/read/28345145/air-pollution-and-short-term-clinical-outcomes-of-patients-with-acute-myocardial-infarction
#19
Min Woo Lee, Byoung Geol Choi, Suhng Wook Kim, Seung-Woon Rha, Min Suk Shim, Dae Jin Kim, Hong Seog Seo, Dong Joo Oh, Myung Ho Jeong
1.Ambient air pollution is well-known to be a serious risk factor for cardiovascular diseases, stroke, and death. However, the association between air pollutants (AP) exposure and short-term clinical outcomes in acute myocardial infarction (AMI) patients (pts) is not well elucidated yet. 2.In the present study, 37,880 AMI pts were enrolled finally from October 2005 to December 2013 in a nationwide large-scale, prospective, multicenter Korea AMI registry (KAMIR registry; http://www.kamir.or.kr). We obtained data on AP (e...
March 27, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28344958/perioperative-administration-of-propranolol-to-women-undergoing-ovarian-cancer-surgery-a-pilot-study
#20
Hye-In Jang, Soo-Hyun Lim, Yoo-Young Lee, Tae-Joong Kim, Chel Hun Choi, Jeong-Won Lee, Byoung-Gie Kim, Duk-Soo Bae
OBJECTIVE: This study was done to evaluate whether perioperative propranolol (ß-blocker) in ovarian cancer patients undergoing debulking surgery reduced perioperative tumor growth induced by surgical stress. METHODS: This was a prospective randomized single institution analysis. The primary objective was to compare the changes in CA 125 level (changes between preoperation day 2 and postoperative day 7). As a study arm, patients received a low dose of propranolol 40 mg/day (4×10 mg) starting two days before surgery and 40 mg twice daily for three days following surgery...
March 2017: Obstetrics & Gynecology Science
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