keyword
https://read.qxmd.com/read/38535378/monoaminergic-systems-in-flight-induced-potentiation-of-phonotactic-behavior-in-female-crickets-gryllus-bimaculatus
#1
JOURNAL ARTICLE
Maxim Mezheritskiy, Victoria Melnikova, Varvara Dyakonova, Dmitry Vorontsov
We have recently shown that experience of flight remarkably enhanced subsequent terrestrial phonotaxis in females in response to the male calling song. Here, we elucidated the possible roles of octopamine and serotonin in the enhancing effect of flying on phonotactic behavior. Octopamine is known to be released into the hemolymph during flight in insects; however, the octopamine receptor antagonist epinastine did not abolish the effects of flight in our study. On the contrary, the drug significantly potentiated the influence of flying on phonotactic behavior...
March 9, 2024: Insects
https://read.qxmd.com/read/38533112/a-simultaneous-eeg-fnirs-dataset-of-the-visual-cognitive-motivation-study-in-healthy-adults
#2
JOURNAL ARTICLE
Tustanah Phukhachee, Thanate Angsuwatanakul, Keiji Iramina, Boonserm Kaewkamnerdpong
This article described a publicly available dataset of the visual cognitive motivation study in healthy adults. To gain an in-depth understanding and insights into motivation, Electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) were measured simultaneously at shared locations while participants performed a visual cognitive motivation task. The participants' choices in the cognitive motivation task were recorded. The effects of their motivation were identified in the recognition test afterward...
April 2024: Data in Brief
https://read.qxmd.com/read/38532790/inter-brain-desynchronization-in-social-interaction-a-consequence-of-subjective-involvement
#3
JOURNAL ARTICLE
Tom Froese, Chen Lam Loh, Finda Putri
Hyperscanning approaches to human neuroscience aim to uncover the neural mechanisms of social interaction. They have been largely guided by the expectation that increased levels of engagement between two persons will be supported by higher levels of inter-brain synchrony (IBS). A common approach to measuring IBS is phase synchrony in the context of EEG hyperscanning. Yet the growing number of experimental findings does not yield a straightforward interpretation, which has prompted critical reflections about the field's theoretical and methodological principles...
2024: Frontiers in Human Neuroscience
https://read.qxmd.com/read/38528956/activation-of-nucleus-accumbens-projections-to-the-ventral-tegmental-area-alters-molecular-signaling-and-neurotransmission-in-the-reward-system
#4
JOURNAL ARTICLE
Alaa Khayat, Rami Yaka
The nucleus accumbens (NAc) and the ventral tegmental area (VTA) are integral brain regions involved in reward processing and motivation, including responses to drugs of abuse. Previously, we have demonstrated that activation of NAc-VTA afferents during the acquisition of cocaine conditioned place preference (CPP) reduces the rewarding properties of cocaine and diminished the activity of VTA dopamine neurons. In the current study, we examined the impact of enhancing these inhibitory inputs on molecular changes and neurotransmission associated with cocaine exposure...
2024: Frontiers in Molecular Neuroscience
https://read.qxmd.com/read/38527155/a-literature-review-of-outcome-and-treatment-options-after-acquired-brain-injury-suggestions-for-adult-offenders-using-knowledge-from-the-general-population
#5
JOURNAL ARTICLE
Esther Q J de Geus, Maarten V Milders, Joan E van Horn, Frank A Jonker, Thijs Fassaert, Juliette C Hutten, Femke Kuipers, Christel Grimbergen, Siri D S Noordermeer
BACKGROUND: Acquired brain injury (ABI) is a major health problem, often with negative effects on behaviour and mental health as well as cognition. Prevalence of ABI is exceptionally high among offenders and increases their re-offending risk. Information on risk factors for ABI and its outcomes among offenders that could guide effective treatment for them is, nevertheless, scarce and dispersed. However, there is a more substantial literature about the general population that could inform work with brain-injured offenders, especially when selecting for samples or subgroups with similar relevant characteristics, such as lower socio-economic status (SES), pre-injury lower tested intelligence score (<85) and pre-injury mental health problems...
March 25, 2024: Criminal Behaviour and Mental Health: CBMH
https://read.qxmd.com/read/38521203/the-neurobiological-effects-of-senescence-on-dopaminergic-system-a-comprehensive-review
#6
REVIEW
Gabriel S Rocha, Marco Aurelio M Freire, Karina M Paiva, Rodrigo F Oliveira, Paulo Leonardo A G Morais, José Ronaldo Santos, José Rodolfo L P Cavalcanti
Over time, the body undergoes a natural, multifactorial, and ongoing process named senescence, which induces changes at the molecular, cellular, and micro-anatomical levels in many body systems. The brain, being a highly complex organ, is particularly affected by this process, potentially impairing its numerous functions. The brain relies on chemical messengers known as neurotransmitters to function properly, with dopamine being one of the most crucial. This catecholamine is responsible for a broad range of critical roles in the central nervous system, including movement, learning, cognition, motivation, emotion, reward, hormonal release, memory consolidation, visual performance, sexual drive, modulation of circadian rhythms, and brain development...
March 21, 2024: Journal of Chemical Neuroanatomy
https://read.qxmd.com/read/38520370/brain-based-sex-differences-in-schizophrenia-a-systematic-review-of-fmri-studies
#7
REVIEW
Mohammad Amin Salehi, Rasa Zafari, Soheil Mohammadi, Mohammad Shahrabi Farahani, Mahsa Dolatshahi, Hamid Harandi, Amirhossein Poopak, Stephen R Dager
Schizophrenia is a chronic psychiatric disorder with characteristic symptoms of delusions, hallucinations, lack of motivation, and paucity of thought. Recent evidence suggests that the symptoms of schizophrenia, negative symptoms in particular, vary widely between the sexes and that symptom onset is earlier in males. A better understanding of sex-based differences in functional magnetic resonance imaging (fMRI) studies of schizophrenia may provide a key to understanding sex-based symptom differences. This study aimed to summarize sex-based functional magnetic resonance imaging (fMRI) differences in brain activity of patients with schizophrenia...
April 2024: Human Brain Mapping
https://read.qxmd.com/read/38519794/perinatal-compromise-affects-development-form-and-function-of-the-hippocampus-part-one-clinical-studies
#8
REVIEW
Tegan A White, Suzanne L Miller, Amy E Sutherland, Beth J Allison, Emily J Camm
The hippocampus is a neuron-rich specialised brain structure that plays a central role in the regulation of emotions, learning and memory, cognition, spatial navigation, and motivational processes. In human fetal development, hippocampal neurogenesis is principally complete by mid-gestation, with subsequent maturation comprising dendritogenesis and synaptogenesis in the third trimester of pregnancy and infancy. Dendritogenesis and synaptogenesis underpin connectivity. Hippocampal development is exquisitely sensitive to perturbations during pregnancy and at birth...
March 22, 2024: Pediatric Research
https://read.qxmd.com/read/38518891/behavioral-therapy-for-functional-heartburn-recommendation-statements
#9
JOURNAL ARTICLE
Livia Guadagnoli, Rena Yadlapati, John Pandolfino, Alyse Bedell, Anjali U Pandit, Kerry B Dunbar, Ronnie Fass, Richard Gevirtz, C Prakash Gyawali, Stephen E Lupe, Megan Petrik, Megan E Riehl, Jessica Salwen-Deremer, Madison Simons, Kathryn N Tomasino, Tiffany Taft
BACKGROUND & AIMS: Brain-gut behavior therapies (BGBT) are increasingly recognized as effective therapeutic interventions for functional heartburn. However, recommendations regarding candidacy for treatment, initial treatment selection, and navigating treatment non-response have not been established for functional heartburn specifically. The aim of this study was to establish expert-based recommendations for behavioral treatment in patients with functional heartburn. METHODS: The validated RAND/University of California, Los Angeles Appropriateness Method (RAM) was applied to develop recommendations...
March 20, 2024: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/38516877/increased-ventral-anterior-insular-connectivity-to-sports-betting-availability-indexes-problem-gambling
#10
JOURNAL ARTICLE
Damien Brevers, Chris Baeken, Antoine Bechara, Qinghua He, Pierre Maurage, Guillaume Sescousse, Claus Vögele, Joël Billieux
With the advent of digital technologies, online sports betting is spurring a fast-growing expansion. In this study, we examined how sports betting availability modulates the brain connectivity of frequent sports bettors with [problem bettors (PB)] or without [non-problem bettors (NPB)] problematic sports betting. We conducted functional connectivity analyses centred on the ventral anterior insular cortex (vAI), a brain region playing a key role in the dynamic interplay between reward-based processes. We re-analysed a dataset on sports betting availability undertaken in PB (n = 30) and NPB (n = 35)...
March 2024: Addiction Biology
https://read.qxmd.com/read/38515262/the-expectations-and-experiences-of-patients-regarding-the-diagnostic-workup-at-a-specialized-memory-clinic-an-interview-study
#11
JOURNAL ARTICLE
Malin Aspö, Maria Sundell, Myroslava Protsiv, Fleur Wiggenraad, Marie Rydén, Francesca Mangialasche, Miia Kivipelto, Leonie N C Visser
BACKGROUND: Because of the shift towards earlier diagnosis of dementia and/or Alzheimer's disease (AD), increasing numbers of individuals with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are seen in memory clinics. Yet, evidence indicates that there is room for improvement when it comes to tailoring of the diagnostic work-up to the needs of individual patients. To optimize the quality of care, we explored patients' perspectives regarding the diagnostic work-up at a specialized memory clinic...
April 2024: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://read.qxmd.com/read/38512722/comparative-brain-wide-mapping-of-ketamine-and-isoflurane-activated-nuclei-and-functional-networks-in-the-mouse-brain
#12
JOURNAL ARTICLE
Yue Hu, Wenjie Du, Jiangtao Qi, Huoqing Luo, Zhao Zhang, Mengqiang Luo, Yingwei Wang
Ketamine (KET) and isoflurane (ISO) are two widely used general anesthetics, yet their distinct and shared neurophysiological mechanisms remain elusive. In this study, we conducted a comparative analysis of the effects of KET and ISO on c-Fos expression across the mouse brain, utilizing hierarchical clustering and c-Fos-based functional network analysis to evaluate the responses of individual brain regions to each anesthetic. Our findings reveal that KET activates a wide range of brain regions, notably in the cortical and subcortical nuclei involved in sensory, motor, emotional, and reward processing, with the temporal association areas (TEa) as a strong hub, suggesting a top-down mechanism affecting consciousness by primarily targeting higher order cortical networks...
March 21, 2024: ELife
https://read.qxmd.com/read/38510918/autonomic-brain-functioning-and-age-related-health-concerns
#13
REVIEW
Amjad Z Alrosan, Ghaith B Heilat, Khaled Alrosan, Abrar A Aleikish, Aya N Rabbaa, Aseel M Shakhatreh, Ehab M Alshalout, Enaam M A Al Momany
The autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the most well-known alterations in the ANS associated with health issues, including cardiovascular diseases and cognitive decline...
2024: Current research in physiology
https://read.qxmd.com/read/38510800/fronto-striato-network-function-is-reduced-in-major-depressive-disorder
#14
JOURNAL ARTICLE
Reoto Kijima, Keita Watanabe, Naomichi Okamoto, Atsuko Ikenouchi, Hirofumi Tesen, Shingo Kakeda, Reiji Yoshimura
INTRODUCTION: Major depressive disorder (MDD) is a major cause of poor quality of life and disability and is highly prevalent worldwide. Various pathological mechanisms are implicated in MDD, including the reward system. The human brain is equipped with a reward system that is involved in aspects such as motivation, pleasure, and learning. Several studies including a meta-analysis have been reported on the reward system network and MDD. However, to our knowledge, no studies have examined the relationship between the reward system network of drug-naïve, first-episode MDD patients and the detailed symptoms of MDD or age...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38510045/a-metamaterial-unit-cell-based-patch-radiator-for-brain-machine-interface-technology
#15
JOURNAL ARTICLE
Emtiaz Ahmed Mainul, Md Faruque Hossain
This paper presents a novel approach to the design of a brain implantable antenna tailored for brain-machine interface (BMI) technology. The design is based on a U-shaped unit-cell metamaterial (MTM), introducing innovative features to enhance performance and address specific challenges associated with BMI applications. The motivation behind the use of the unit-cell structure is to elongate the electric path within the antenna patch, diverging from a reliance on the electrical properties of the MTM. Consequently, the unit cell is connected to an inset-fed transmission line and shorted to the ground...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38504049/towards-translational-biomarkers-for-motivation-a-commentary-on-noback-et-al-%C3%A2-2024
#16
JOURNAL ARTICLE
Sarah M Etuk, Michael T Treadway
No abstract text is available yet for this article.
March 19, 2024: Cognitive, Affective & Behavioral Neuroscience
https://read.qxmd.com/read/38504048/preclinical-animal-models-and-assays-of-neuropsychiatric-disorders-old-problems-and-new-vistas-introduction-to-the-special-issue
#17
JOURNAL ARTICLE
Stan Floresco, Angela Roberts, Emma Robinson, Diego A Pizzagalli
Preclinical research is an essential aspect of biomedical science that aids in clarifying the pathophysiology of underlying illness and devising new treatments. This special issues brings together original research and review papers that pertain to the development of novel models and behavioral assays of symptoms of neuropsychiatric disorders, which may help to refine preclinical studies and to improve their translatability to the human condition.
March 19, 2024: Cognitive, Affective & Behavioral Neuroscience
https://read.qxmd.com/read/38499081/iuphar-themed-issue-new-strategies-for-medications-to-treat-substance-use-disorders
#18
REVIEW
Surya Pandey, Courtney A Miller
Substance use disorders (SUD) are chronic relapsing disorders governed by continually shifting cycles of positive drug reward experiences and drug withdrawal-induced negative experiences. A large body of research points to plasticity within systems regulating emotional, motivational, and cognitive processes as drivers of continued compulsive pursuit and consumption of substances despite negative consequences. This plasticity is observed at all levels of analysis from molecules to networks, providing multiple avenues for intervention in SUD...
March 16, 2024: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://read.qxmd.com/read/38497429/delineating-cognitive-resilience-using-fractal-regulation-cross-sectional-and-longitudinal-evidence-from-the-rush-memory-and-aging-project
#19
JOURNAL ARTICLE
Peng Li, Chenlu Gao, Lei Yu, Lei Gao, Ruixue Cai, David A Bennett, Julie A Schneider, Aron S Buchman, Kun Hu
INTRODUCTION: Degradation of fractal patterns in actigraphy independently predicts dementia risk. Such observations motivated the study to understand the role of fractal regulation in the context of neuropathologies. METHODS: We examined associations of fractal regulation with neuropathologies and longitudinal cognitive changes in 533 older participants who were followed annually with actigraphy and cognitive assessments until death with brain autopsy performed...
March 18, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://read.qxmd.com/read/38496406/a-randomized-proof-of-mechanism-trial-of-tnf-antagonism-for-motivational-anhedonia-and-related-corticostriatal-circuitry-in-depressed-patients-with-high-inflammation
#20
Michael Treadway, Sarah Etuk, Jessica Cooper, Shabnam Hossein, Emma Hahn, Samantha Betters, Shiyin Liu, Amanda Arulpragasam, Brittany DeVries, Nadia Irfan, Makiah Nuutinen, Evanthia Wommack, Bobbi Woolwine, Mandakh Bekhbat, Philip Kragel, Jennifer Felger, Ebrahim Haroon, Andrew Miller
Chronic, low-grade inflammation has been associated with motivational deficits in patients with major depression (MD). In turn, impaired motivation has been linked to poor quality of life across psychiatric disorders. We thus determined effects of the anti-inflammatory drug infliximab-a potent tumor necrosis factor (TNF) antagonist-on behavioral and neural measures of motivation in 42 medically stable, unmedicated MD patients with a C-reactive protein > 3mg/L. All patients underwent a double-blind, placebo-controlled, single-dose, randomized clinical trial with infliximab (5mg/kg) versus placebo...
March 5, 2024: Research Square
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