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https://www.readbyqxmd.com/read/29232770/review-article-nexus-criteria-to-rule-out-cervical-spine-injury-among-older-patients-a-systematic-review
#1
REVIEW
Gabriel Paykin, Gerard O'Reilly, Helen Ackland, Biswadev Mitra
The National Emergency X-Radiography Utilization Study (NEXUS) criteria were derived from a heterogeneous group of adult blunt trauma patients, with the outcome measure assessed most commonly using plain X-ray radiographs. Recent observations have suggested inadequacy of these criteria for excluding injury in population subgroups such as the elderly. The aim of this systematic review was to determine the sensitivity of the NEXUS criteria in excluding cervical spine injury among older patients aged ≥65 years...
December 12, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29232761/profile-of-ethnicity-living-arrangements-and-loneliness-amongst-older-adults-in-aotearoa-new-zealand-a-national-cross-sectional-study
#2
Hamish A Jamieson, Helen M Gibson, Rebecca Abey-Nesbit, Annabel Ahuriri-Driscoll, Sally Keeling, Philip J Schluter
OBJECTIVE: To explore the patterns of living arrangements, ethnicity and loneliness amongst older adults (aged 65+ years) living at home. METHODS: National interRAI-HC (International Residential Assessment Instrument-Home Care) assessments conducted between 1 September 2012 and 31 January 2016 were analysed. Analysis focused on the associations between loneliness and both ethnic groups and living arrangements. RESULTS: There were 71 859 eligible participants, with average age 82...
December 12, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29232162/efficacy-and-safety-of-biosimilar-sar342434-insulin-lispro-in-adults-with-type-2-diabetes-also-using-insulin-glargine-sorella-2-study
#3
Karl-Michael Derwahl, Timothy S Bailey, Karin Wernicke-Panten, Lin Ping, Suzanne Pierre
BACKGROUND: SAR342434 (SAR-Lis) is a biosimilar (follow-on) of insulin lispro (U100; Humalog®; Ly-Lis). This study aimed to show similar efficacy, safety, and immunogenicity of SAR-Lis versus Ly-Lis in adult patients with type 2 diabetes mellitus (T2DM) treated with multiple daily injections, while using insulin glargine (GLA-100; Lantus®) as basal insulin. METHODS: SORELLA 2 was a 6-month, randomized, open-label, Phase 3 study (NCT02294474). Insulin doses were adjusted to achieve fasting and 2-h postprandial glucose targets according to American Diabetes Association guidelines...
December 12, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29231962/symptoms-reported-by-frail-elderly-adults-independently-predict-30-day-hospital-readmission-or-emergency-department-care
#4
Lynn S Borkenhagen, Rozalina G McCoy, Rachel D Havyer, Stephanie M Peterson, James M Naessens, Paul Y Takahashi
OBJECTIVES: To assess the degree to which self-reported symptoms predict unplanned readmission or emergency department (ED) care within 30 days of high-risk, elderly adults enrolled in a posthospitalization care transition program (CTP). DESIGN: Retrospective cohort study. SETTING: Posthospitalization CTP at Mayo Clinic, Rochester, Minnesota, from January 1, 2013, through March 3, 2015. PARTICIPANTS: Frail, elderly adults (N = 230; mean age 83...
December 12, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29231128/exploring-the-experiences-of-persons-who-frequently-visit-the-emergency-department-for-mental-health-related-reasons
#5
Amanda Digel Vandyk, Lisa Young, Colleen MacPhee, Katharine Gillis
In this qualitative study, the experiences of persons who frequently visit the emergency department (ED) for mental health-related reasons were explored. Interpretive Description guided the design, and data were collected through interviews with 10 adults who made 12+ ED visits within a 1-year time frame (2015). Thematic analysis was used to analyze data inductively. The participants' experiences were described with the help of three themes emerging from the data: The Experience, The Providers, and Protective Factors...
December 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/29230555/non-visualization-of-the-ovary-on-ct-or-ultrasound-in-the-ed-setting-utility-of-immediate-follow-up-imaging
#6
Elena Motuzko, Maria Solis, Moazzem Kazi, Ron Gefen
PURPOSE: In the setting of female patients in the ED receiving both a CT scan and ultrasound of the pelvis, we compared the studies to assess the diagnostic value of non-visualization of the ovary in predicting the absence of ovarian disease. METHODS: A retrospective review of the electronic medical record identified adult female non-pregnant patients who received both a CT abdomen and pelvis and a transabdominal and transvaginal pelvic ultrasound within a 48-h period through the emergency department...
December 11, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29230194/acute-flaccid-paralysis-by-enterovirus-d68-infection-first-italian-description-in-adult-patient-and-role-of-electrophysiology
#7
Marco Ceccanti, Emilia Sbardella, Federica Letteri, Manuela De Michele, Anne Falcou, Federica Romanzi, Emanuela Onesti, Maurizio Inghilleri
A Peruvian woman was admitted to the Emergency Department, due to an acute flaccid paralysis (AFP) of the upper limbs that progressively involved also lower limbs and respiratory muscles. She previously suffered from non-Hodgkin's lymphoma and had to undergo hematopoietic stem cell transplantation. A magnetic resonance imaging showed a T2 hyperintensity in the anterior and central region of the cervical segment with an elective involvement of gray matter. This finding, combined with other clinical, laboratory, and electrophysiological data, led to a diagnosis of AFP...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29229907/live-bearing-promotes-the-evolution-of-sociality-in-reptiles
#8
Ben Halliwell, Tobias Uller, Barbara R Holland, Geoffrey M While
Identifying factors responsible for the emergence and evolution of social complexity is an outstanding challenge in evolutionary biology. Here we report results from a phylogenetic comparative analysis of over 1000 species of squamate reptile, nearly 100 of which exhibit facultative forms of group living, including prolonged parent-offspring associations. We show that the evolution of social groupings among adults and juveniles is overwhelmingly preceded by the evolution of live birth across multiple independent origins of both traits...
December 11, 2017: Nature Communications
https://www.readbyqxmd.com/read/29229552/caspase-6-is-a-dispensable-enabler-of-adult-mammalian-axonal-degeneration
#9
V Woo, C Cheng, A Duraikannu, A Chandrasekhar, K Purdy, J A Martinez, D W Zochodne
The progress of axonal degeneration (AxD) following injury or insult impacts both recovery from axonal transection and protection of axons from diverse insults, or axonopathy. Here we provide evidence that increases in capase-6 (Casp6) expression and action contribute to the progression of AxD. The expression of Casp6 protein and mRNA in distal branches of sensory axons undergoing AxD was confirmed. We developed and utilized a new model of axonopathy in live mice by serially visualizing the viability of cutaneous axons in the ear pinna that expressed an axonal YFP transgene, in response to capasaicin-induced AxD...
December 8, 2017: Neuroscience
https://www.readbyqxmd.com/read/29229501/proceedings-of-the-2017-santa-fe-bone-symposium-insights-and-emerging-concepts-in-the-management-of-osteoporosis
#10
REVIEW
E Michael Lewiecki, John P Bilezikian, John J Carey, Richard M Dell, Catherine M Gordon, Steven T Harris, Michael R McClung, Paul D Miller, Michael Rosenblatt
The 18th Annual Santa Fe Bone Symposium was held on August 4-5, 2017, in Santa Fe, New Mexico, USA. The symposium convenes health-care providers and clinical researchers to present and discuss clinical applications of recent advances in research of skeletal diseases. The program includes lectures, oral presentations by endocrinology fellows, case-based panel discussions, and breakout sessions on topics of interest, with emphasis on participation and interaction of all participants. Topics included the evaluation and treatment of adult survivors with pediatric bone diseases, risk assessment and management of atypical femur fractures, nonpharmacologic strategies in the care of osteoporosis, and skeletal effects of parathyroid hormone with opportunities for therapeutic intervention...
November 20, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29229079/city-housing-atmospheric-pollutant-impact-on-emergency-visit-for-asthma-a-classification-and-regression-tree-approach
#11
Julie Mazenq, Jean-Christophe Dubus, Jean Gaudart, Denis Charpin, Gilles Viudes, Guilhem Noel
INTRODUCTION: Particulate matter, nitrogen dioxide (NO2) and ozone are recognized as the three pollutants that most significantly affect human health. Asthma is a multifactorial disease. However, the place of residence has rarely been investigated. We compared the impact of air pollution, measured near patients' homes, on emergency department (ED) visits for asthma or trauma (controls) within the Provence-Alpes-Côte-d'Azur region. METHODS: Variables were selected using classification and regression trees on asthmatic and control population, 3-99 years, visiting ED from January 1 to December 31, 2013...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29229057/functional-limitations-in-adults-who-utilize-chiropractic-or-osteopathic-manipulation-in-the-united-states-analysis-of-the-2012-national-health-interview-survey
#12
Mary L Forte, Michele Maiers
OBJECTIVES: The goals of this study were to identify self-reported differences in function, comorbidities, and medical service utilization among adults who reported using chiropractic and/or osteopathic manipulation in the 2012 National Health Interview Survey, and to compare these between older and younger adults. METHODS: We conducted a descriptive study of adults aged 18 or older who were included in the 2012 National Health Interview Survey and the Alternative Medicine Questionnaire...
November 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29228152/effectiveness-of-nutritional-interventions-addressed-to-elderly-persons-umbrella-systematic-review-with-meta-analysis
#13
Andrea Poscia, Sonja Milovanovic, Daniele Ignazio La Milia, Mariusz Duplaga, Marcin Grysztar, Francesco Landi, Umberto Moscato, Nicola Magnavita, Agnese Collamati, Walter Ricciardi
Background: The number of Europeans aged over 65 will double between 2010 and 2060, reaching 30% of the European population. Nutrition is emerging as a key element of healthy life since both obesity and malnutrition are established risk factors for morbidity and disability. The aim of this umbrella review (UR) is to summarize the findings of all current systematic reviews (SRs) and meta-analyzes (MAs) on the effectiveness of nutritional intervention designed to promote healthy aging in older individuals...
December 8, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29228033/visual-mismatch-negativity-to-vanishing-parts-of-objects-in-younger-and-older-adults
#14
István Sulykos, Zsófia Anna Gaál, István Czigler
We investigated visual mismatch negativity (vMMN) to vanishing parts of continuously present objects by comparing the event-related potentials (ERPs) to infrequently (deviant) and frequently (standard) disappearing parts of the objects. This paradigm both excludes low-level stimulus-specific adaptation differences between the responses to deviants and standards, and increases the ecological validity of the stimuli. In comparison to frequently disappearing parts of the stimulus objects, infrequently vanishing parts elicited posterior negative event-related brain activity (vMMN)...
2017: PloS One
https://www.readbyqxmd.com/read/29227412/validity-and-responsiveness-to-change-of-the-30-second-chair-stand-test-in-older-adults-admitted-to-an-emergency-department
#15
Inge Hansen Bruun, Christian B Mogensen, Birgitte Nørgaard, Berit Schiøttz-Christensen, Thomas Maribo
BACKGROUND AND PURPOSE: Few physical performance measurement tools are validated for acutely admitted older adults, and for this reason we aimed to examine the validity and responsiveness to change of the 30-second Chair-Stand Test (30s-CST) used to assess physical performance in older adults admitted to a short-stay unit in an emergency department. METHODS: Construct validity of the 30s-CST, using 8 as a cutoff point for dependency in activities of daily living, was examined using 207 patients...
December 7, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29227336/family-caregivers-experiences-of-within-hospital-handoffs-for-older-adults-in-acute-care
#16
Alycia A Bristol, Janice D Crist, Linda R Phillips, Kimberly D Shea, Cheryl Lacasse
Family caregivers' experiences during within-hospital handoffs between acute care units are not well understood. Qualitative description methodology was employed to describe family caregivers' experiences during their loved ones' handoffs. Semistructured interviews were conducted with 10 caregivers of hospitalized older adults. Three themes emerged: Lack of care coordination, Muddling through handoffs alone, and Wariness toward the care delivery system. Findings can help clinicians shape their interactions with caregivers to maximize their involvement in post-hospital care...
December 8, 2017: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/29227242/social-class-and-alcohol-use-by-youth-different-drinking-behaviors-different-associations
#17
Hilde Pape, Ingeborg Rossow, Jasmina Burdzovic Andreas, Thor Norström
OBJECTIVE: Low socioeconomic status (SES) is related to hazardous alcohol use in adults, and the association seems to be stronger for more deviant and harmful drinking behaviors. We examined whether a similar pattern was present among adolescents. METHOD: Data stem from a Norwegian school survey of 14- to 17-year-olds (n = 12,966; response rate in participating schools: 86%). Parental education (high/ middle vs. low) was our main SES indicator. The outcomes comprised lifetime and past-year drinking and intoxication, and past-year symptoms of excessive drinking...
January 2018: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/29226455/perceptions-of-oral-health-among-older-cambodians-and-their-caregivers-a-qualitative-study
#18
Rithvitou Horn, Chanlay Heng, Chamrouen Chea, Chanthyda Sieng, Chenlay Louv, Bathsheba Turton, Callum Durward, Noor Hayaty Abu Kasim
OBJECTIVE: Older adults (those above the age of 60) are an emerging demographic in Cambodia, and very little is understood about their oral health experiences, needs, perceptions and behaviours. The aim of this study was to explore the oral health experiences, practices and perceptions of a convenience sample of a small but diverse group of older adults in Cambodia. METHOD: A cross-sectional qualitative study in which focus group interviews were conducted by 5 trained senior Cambodian dental students...
December 11, 2017: Gerodontology
https://www.readbyqxmd.com/read/29226316/interpersonal-predictors-of-stress-generation-is%C3%A2-there-a-super-factor
#19
Josephine H Shih, Matthew G Barstead, Nicole Dianno
Hammen's (1991, Journal of Abnormal Psychology, 100, 555-561) seminal paper on stress generation highlighted the reciprocal relationship between stress and depression. Not only does stress predict depression, but women with a diagnosis of depression also experienced subsequent increased levels of stress. In the ensuing years, depression researchers have moved beyond clinical predictors and examined whether depression vulnerability factors also contribute to stress generation. This interest has led to a growing focus on interpersonal vulnerability factors that contribute to stress generation...
December 10, 2017: British Journal of Psychology
https://www.readbyqxmd.com/read/29225800/recommendations-for-imaging-based-diagnosis-and-management-of-renal-angiomyolipoma-associated-with-tuberous-sclerosis-complex
#20
REVIEW
María José Buj Pradilla, Teresa Martí Ballesté, Roser Torra, Felipe Villacampa Aubá
Renal angiomyolipomas are found in up to 80% of tuberous sclerosis complex (TSC) patients. Although these tumours are usually asymptomatic, lesions >3 cm in diameter are prone to bleeding and up to 10% of TSC patients may experience a massive and potentially fatal retroperitoneal haemorrhage. Diagnosis can be complicated because of the initial lack of symptoms and the fat-poor content of atypical renal angiomyolipomas. After diagnosis, tumour growth and the emergence of new tumours must be monitored. Treatment with mammalian target of rapamycin (mTOR) inhibitors can reduce tumour size and is indicated in patients with TSC-associated renal angiomyolipomas >3 cm in diameter...
December 2017: Clinical Kidney Journal
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