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https://www.readbyqxmd.com/read/29679920/optimizing-text-for-an-individual-s-visual-system-the-contribution-of-visual-crowding-to-reading-difficulties
#1
Sung Jun Joo, Alex L White, Douglas J Strodtman, Jason D Yeatman
Reading is a complex process that involves low-level visual processing, phonological processing, and higher-level semantic processing. Given that skilled reading requires integrating information among these different systems, it is likely that reading difficulty-known as dyslexia-can emerge from impairments at any stage of the reading circuitry. To understand contributing factors to reading difficulties within individuals, it is necessary to diagnose the function of each component of the reading circuitry. Here, we investigated whether adults with dyslexia who have impairments in visual processing respond to a visual manipulation specifically targeting their impairment...
March 23, 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29679544/1-f-neural-noise-and-electrophysiological-indices-of-contextual-prediction-in-aging
#2
S Dave, T A Brothers, T Y Swaab
Prediction of upcoming words during reading has been suggested to enhance the efficiency of discourse processing. Emerging models have postulated that predictive mechanisms require synchronous firing of neural networks, but to date, this relationship has been investigated primarily through oscillatory activity in narrow frequency bands. A recently-developed measure proposed to reflect broadband neural activity - and thereby synchronous neuronal firing - is 1/f neural noise extracted from EEG spectral power...
April 18, 2018: Brain Research
https://www.readbyqxmd.com/read/29679360/mental-health-of-the-male-adolescent-and-young-man-the-copenhagen-statement
#3
REVIEW
Timothy R Rice, Lesha D Shah, Pilar Trelles, Shih-Ku Lin, Dinne Skjærlund Christensen, Andreas Walther, Leo Sher
BACKGROUND: Male adolescents and young men benefit when their mental health care is specialized to match their unique gendered and developmental needs. Sensitivity to the social circumstances of this population is important; additionally, the emerging ability to tailor care through knowledge gleaned from the intersection of psychiatry, neurology, and endocrinology informs care. DATA SOURCES: This article summarized the views of six experts in the area of the adolescent and young adult male mental health...
April 20, 2018: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/29679311/is-it-possible-to-manipulate-scelionidae-wasps-preference-to-a-target-host
#4
R Tognon, J Sant'Ana, L R Redaelli, A L Meyer
Parasitoid host selection is mainly mediated by chemical cues, which can be adjusted by experience, changing their innate behavior. Therefore, this study evaluated if immature experience (pre-imaginal conditioning) on eggs and volatiles from different host eggs has influence on parasitism and chemotaxic behavior of Telenomus podisi Ashmead and/or Trissolcus basalis Wollaston (Hymenoptera: Scelionidae). Both wasp species were submitted to a multiple-choice parasitism test among Euschistus heros (Fabricius), Piezodorus guildinii (Westwood), and Nezara viridula L...
April 20, 2018: Neotropical Entomology
https://www.readbyqxmd.com/read/29679226/national-estimates-of-emergency-department-visits-for-antibiotic-adverse-events-among-adults-united-states-2011-2015
#5
Andrew I Geller, Maribeth C Lovegrove, Nadine Shehab, Lauri A Hicks, Mathew R P Sapiano, Daniel S Budnitz
BACKGROUND: Detailed, nationally representative data describing high-risk populations and circumstances involved in antibiotic adverse events (AEs) can inform approaches to prevention. OBJECTIVE: Describe US burden, rates, and characteristics of emergency department (ED) visits by adults for antibiotic AEs. DESIGN: Nationally representative, public health surveillance of adverse drug events (National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance [NEISS-CADES]) and a nationally projected database of dispensed prescriptions (QuintilesIMS), 2011-2015...
April 20, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29678754/sex-and-age-dependent-effects-of-orexin-1-receptor-blockade-on-open-field-behavior-and-neuronal-activity
#6
Shannon R Blume, Hannah Nam, Sandra Luz, Debra A Bangasser, Seema Bhatnagar
Adolescence is a sensitive and critical period in brain development where psychiatric disorders such as anxiety, depression and post-traumatic stress disorder are more likely to emerge following a stressful life event. Females are two times more likely to suffer from psychiatric disorders than males. Patients with these disorders show alterations in orexins (also called hypocretins), important neuropeptides that regulate arousal, wakefulness and the hypothalamic-pituitary-adrenal axis activity. Little is known on the role of orexins in mediating arousal behaviors in male and female rats during adolescence or adulthood...
April 17, 2018: Neuroscience
https://www.readbyqxmd.com/read/29678270/multi-directional-reach-test-in-south-asian-children-normative-reference-scores-from-5-year-to-12-years-old
#7
Kavita Sharma, Asir John Samuel, Divya Midha, Vencita Priyanka Aranha, Kanimozhi Narkeesh, Narkeesh Arumugam
Multi-directional reach test (MRT) emerged as a valid and reliable assessment tool for balance evaluation among elderly. The normative reference scores have been established in adults and elderly people, but they were not yet established for children. Hence, we aimed at establishing the normative reference scores of MRT among the school going children aged between 5 and 12 years. Children (N = 194; 124 males, 70 females) were recruited by the stratified random sampling for the normative study. MRT was performed by the custom made, multi-directional reach estimator...
March 27, 2018: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/29678193/treating-prolonged-grief-disorder-with-prolonged-grief-specific-cognitive-behavioral-therapy-study-protocol-for-a-randomized-controlled-trial
#8
Rita Rosner, Eline Rimane, Anna Vogel, Jörn Rau, Maria Hagl
BACKGROUND: Prolonged grief disorder (PGD) has emerged as a well-defined and relatively common mental disorder that will be included in the upcoming revision of the International Classification of Diseases. Recent trials with grief-specific, mostly cognitive behavioral interventions for patients with a clinically relevant diagnosis of PGD showed large effect sizes. However, a small trial suggested that non-specific behavioral activation might suffice to improve PGD. So, more evidence for the relative efficacy of grief-specific treatments is needed, as is more research on the predictors of treatment success...
April 20, 2018: Trials
https://www.readbyqxmd.com/read/29678188/doing-battle-with-the-monster-how-high-risk-heterosexuals-experience-and-successfully-manage-hiv-stigma-as-a-barrier-to-hiv-testing
#9
Marya Gwadz, Noelle R Leonard, Sylvie Honig, Robert Freeman, Alexandra Kutnick, Amanda S Ritchie
BACKGROUND: Annual HIV testing is recommended for populations at-risk for HIV in the United States, including heterosexuals geographically connected to urban high-risk areas (HRA) with elevated rates of HIV prevalence and poverty, who are primarily African American/Black or Hispanic. Yet this subpopulation of "individuals residing in HRA" (IR-HRA) evidence low rates of regular HIV testing. HIV stigma is a recognized primary barrier to testing, in part due to its interaction with other stigmatized social identities...
April 20, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29677688/relating-shape-weight-based-self-esteem-depression-and-anxiety-with-weight-and-perceived-physical-health-among-young-adults
#10
Rebecca C Kamody, Idia B Thurston, Kristina M Decker, Caroline C Kaufman, Kendrin R Sonneville, Tracy K Richmond
Simultaneous contributions of self-esteem, depression, and anxiety to weight and perceived physical health in young adults is understudied. A diverse sample of 424 young adults completed measures of shape/weight based self-esteem, depression, anxiety, and perceived physical health. Height and weight were measured to calculate body mass index (BMI). Latent profile analysis was conducted to derive patterns of depression, anxiety, and shape/weight based self-esteem. Then, we examined the association of the profiles with weight status and perceived physical health...
April 17, 2018: Body Image
https://www.readbyqxmd.com/read/29677082/artificial-intelligence-can-predict-daily-trauma-volume-and-average-acuity
#11
David P Stonko, Bradley M Dennis, Richard D Betzold, Allan B Peetz, Oliver L Gunter, Oscar D Guillamondegui
INTRODUCTION: The goal of this study was to integrate temporal and weather data in order to create an artificial neural network (ANN) to predict trauma volume, the number of emergent operative cases, and average daily acuity at a level 1 trauma center. METHODS: Trauma admission data from TRACS and weather data from the National Oceanic and Atmospheric Administration (NOAA) was collected for all adult trauma patients from July 2013-June 2016. The ANN was constructed using temporal (time, day of week), and weather factors (daily high, active precipitation) to predict four points of daily trauma activity: number of traumas, number of penetrating traumas, average ISS, and number of immediate OR cases per day...
April 19, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29676956/high-intensity-interval-training-after-stroke-an-opportunity-to-promote-functional-recovery-cardiovascular-health-and-neuroplasticity
#12
Jennifer Crozier, Marc Roig, Janice J Eng, Marilyn MacKay-Lyons, Joyce Fung, Michelle Ploughman, Damian M Bailey, Shane N Sweet, Nicholas Giacomantonio, Alexander Thiel, Michael Trivino, Ada Tang
INTRODUCTION: Stroke is the leading cause of adult disability. Individuals poststroke possess less than half of the cardiorespiratory fitness (CRF) as their nonstroke counterparts, leading to inactivity, deconditioning, and an increased risk of cardiovascular events. Preserving cardiovascular health is critical to lower stroke risk; however, stroke rehabilitation typically provides limited opportunity for cardiovascular exercise. Optimal cardiovascular training parameters to maximize recovery in stroke survivors also remains unknown...
April 1, 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29676780/retrospective-evaluation-of-a-restrictive-transfusion-strategy-in-older-adults-with-hip-fracture
#13
Lorene Zerah, Lucile Dourthe, Judith Cohen-Bittan, Marc Verny, Mathieu Raux, Anthony Mézière, Frédéric Khiami, Cendrine Tourette, Christian Neri, Yannick Le Manach, Bruno Riou, Hélène Vallet, Jacques Boddaert
OBJECTIVES: To compare the association between a restrictive transfusion strategy and cardiovascular complications during hospitalization for hip fracture with the association between a liberal transfusion strategy and cardiovascular complications, accounting for all transfusions from the emergency department to postacute rehabilitation settings. DESIGN: Retrospective study. SETTING: Perioperative geriatric care unit. PARTICIPANTS: All individuals aged 70 and older admitted to the emergency department for hip fracture and hospitalized in our perioperative geriatric care unit (N=667; n=193 in the liberal transfusion group, n=474 in the restrictive transfusion group) from July 2009 to April 2016...
April 20, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29676680/midline-central-fluid-percussion-model-of-traumatic-brain-injury-in-pediatric-and-adolescent-rats
#14
Rachel K Rowe, Jordan L Harrison, Timothy W Ellis, P David Adelson, Jonathan Lifshitz
OBJECTIVE Experimental traumatic brain injury (TBI) models hold significant validity to the human condition, with each model replicating a subset of clinical features and symptoms. TBI is the leading cause of mortality and morbidity in children and teenagers; thus, it is critical to develop preclinical models of these ages to test emerging treatments. Midline fluid percussion injury (FPI) might best represent mild and diffuse clinical brain injury because of the acute behavioral deficits, the late onset of behavioral morbidities, and the absence of gross histopathology...
April 20, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29675787/meropenem-vaborbactam-a-carbapenem-and-beta-lactamase-inhibitor-with-activity-against-carbapenem-resistant-enterobacteriaceae
#15
REVIEW
Young R Lee, Nathaniel T Baker
Meropenem-vaborbactam is a carbapenem and β-lactamase inhibitor combination that is newly indicated for the treatment of complicated urinary tract infections (cUTI), including adult pyelonephritis. Vaborbactam was developed due to emergence of carbapenem-resistant strains of Enterobacteriaceae. In a phase I trial, patients that received meropenem-vaborbactam 2-2 g intravenously over 3 h every 8 h, Cmax was 58.2 ± 10.8 μg/mL for meropenem and 59.0 ± 8.4 μg/mL for vaborbactam. AUC0-8 was 186 ± 33...
April 19, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29674652/the-aesthetic-preference-for-symmetry-dissociates-from-early-emerging-attention-to-symmetry
#16
Yi Huang, Xiaodi Xue, Elizabeth Spelke, Lijie Huang, Wenwen Zheng, Kaiping Peng
Symmetry is a basic geometry property that affects people's aesthetic experience in common ways across cultures and historical periods, but the origins of the universal preference for symmetrical patterns is not clear. We assessed four-year-old children's and adults' reported aesthetic preferences between symmetrical and asymmetrical visual patterns, as well as their spontaneous attentional preferences between the patterns. We found a striking dissociation between these two measures in the children: Children looked longer at the symmetrical patterns, relative to otherwise similar but asymmetrical patterns, but they showed no explicit preference for those patterns...
April 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29674366/can-interprofessional-teamwork-reduce-patient-throughput-times-a-longitudinal-single-centre-study-of-three-different-triage-processes-at-a-swedish-emergency-department
#17
Jenny Liu, Italo Masiello, Sari Ponzer, Nasim Farrokhnia
OBJECTIVE: To determine the impact on emergency department (ED) throughput times and proportion of patients who leave without being seen by a physician (LWBS) of two triage interventions, where comprehensive nurse-led triage was first replaced by senior physician-led triage and then by interprofessional teamwork. DESIGN: Single-centre before-and-after study. SETTING: Adult ED of a Swedish urban hospital. PARTICIPANTS: Patients arriving on weekdays 08:00 to 21:00 during three 1-year periods in the interval May 2012 to November 2015...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29674360/retrospective-observational-study-of-emergency-department-syndromic-surveillance-data-during-air-pollution-episodes-across-london-and-paris-in-2014
#18
Helen E Hughes, Roger Morbey, Anne Fouillet, Céline Caserio-Schönemann, Alec Dobney, Thomas C Hughes, Gillian E Smith, Alex J Elliot
INTRODUCTION: Poor air quality (AQ) is a global public health issue and AQ events can span across countries. Using emergency department (ED) syndromic surveillance from England and France, we describe changes in human health indicators during periods of particularly poor AQ in London and Paris during 2014. METHODS: Using daily AQ data for 2014, we identified three periods of poor AQ affecting both London and Paris. Anonymised near real-time ED attendance syndromic surveillance data from EDs across England and France were used to monitor the health impact of poor AQ...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29674340/opioid-analgesics-and-adverse-outcomes-among-hemodialysis-patients
#19
Julie H Ishida, Charles E McCulloch, Michael A Steinman, Barbara A Grimes, Kirsten L Johansen
BACKGROUND AND OBJECTIVES: Patients on hemodialysis frequently experience pain and may be particularly vulnerable to opioid-related complications. However, data evaluating the risks of opioid use in patients on hemodialysis are limited. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Using the US Renal Data System, we conducted a cohort study evaluating the association between opioid use (modeled as a time-varying exposure and expressed in standardized oral morphine equivalents) and time to first emergency room visit or hospitalization for altered mental status, fall, and fracture among 140,899 Medicare-covered adults receiving hemodialysis in 2011...
April 19, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29673931/-appropriate-use-of-red-blood-cell-transfusion-in-the-emergency-department-before-and-after-a-specific-protocol
#20
M-L Langlais, M Dargère, C Le Niger, D Goetghebeur
The purpose of this study was to assess appropriateness of red blood cell (RBC) transfusion in the emergency department before and after a specific protocol. METHODS: A retrospective monocenter study was realized during two six-month periods at the emergency unit. A protocol based on the French national guidelines (HAS) in 2014 was set up between the two periods. All the adult patients, except in a context of massive transfusion, were included in the study. The principal criteria analysed was the rate of appropriate transfusion...
April 16, 2018: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
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