Carlotta Mutti, Valerio Brunetti, Michela Figorilli, Claudio Liguori, Fabio Pizza, Paola Proserpio, Tommaso Sacco, Giuseppe Pedrazzi, Isabelle Lecomte, Nora Blanchard, Elio Clemente Agostoni, Enrica Bonanni, Diego Centonze, Alessandro Cicolin, Giacomo Della Marca, Luigi Ferini-Strambi, Raffaele Ferri, Gian Luigi Gigli, Francesca Izzi, Rocco Liguori, Raffaele Lodi, Lino Nobili, Liborio Parrino, Fabio Placidi, Monica Puligheddu, Andrea Romigi, Maria Antonietta Savarese, Michele Terzaghi, Giuseppe Plazzi
INTRODUCTION: Narcolepsy is a chronic and rare hypersomnia of central origin characterized by excessive daytime sleepiness and a complex array of symptoms as well as by several medical comorbidities. With growing pharmacological options, polytherapy may increase the possibility of a patient-centered management of narcolepsy symptoms. The aims of our study are to describe a large cohort of Italian patients with narcolepsy who were candidates for pitolisant treatment and to compare patients' subgroups based on current drug prescription (drug-naïve patients in whom pitolisant was the first-choice treatment, switching to pitolisant from other monotherapy treatments, and adding on in polytherapy)...
September 2022: Neurological Sciences