keyword
MENU ▼
Read by QxMD icon Read
search

Thrombus burden

keyword
https://www.readbyqxmd.com/read/28724752/the-fluid-mechanics-of-transcatheter-heart-valve-leaflet-thrombosis-in-the-neo-sinus
#1
Prem A Midha, Vrishank Raghav, Rahul Sharma, Jose F Condado, Ikechukwu U Okafor, Tanya Rami, Gautam Kumar, Vinod H Thourani, Hasan Jilaihawi, Vasilis Babaliaros, Raj R Makkar, Ajit P Yoganathan
Background -Transcatheter heart valve (THV) thrombosis has been increasingly reported. In these studies, thrombus quantification has been based on 2D assessment of a 3D phenomenon. Methods -Post-procedural four-dimensional, volume-rendered CT (4DCT) data of CoreValve, Evolut R, and SAPIEN 3 transcatheter aortic valve replacement (TAVR) patients enrolled in the RESOLVE trial were included in this analysis. Patients on anticoagulation were excluded. SAPIEN 3 and CoreValve/Evolut R patients with and without hypo-attenuated leaflet thickening (HALT) were included in order to study differences between groups...
July 19, 2017: Circulation
https://www.readbyqxmd.com/read/28707447/cto-revascularization-obstacles-and-options-in-balloon-nonpenetrable-lesions
#2
EDITORIAL
On Topaz
CTO lesions resisting balloon crossing are located in moderate/severe tortuous coronary arteries contain more moderate/severe calcification burden and carry a higher J-CTO score as compared with balloon crossable CTO lesions. CTO lesions resisting balloon crossing do not constitute a homogenous group. In 25% of the patients, the resisting CTO was caused by stent restenosis and thrombus is an integral component of CTO in addition to calcium and fibrosis. The excimer laser and rotational/orbital atherectomy are among useful debulking technologies capable of creating a "pilot recanalization channel" in the CTO that enables completion of the revasularization...
July 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28704281/the-diagnostic-value-of-3-dimensional-sampling-perfection-with-application-optimized-contrasts-using-different-flip-angle-evolutions-space-mri-in-evaluating-lower-extremity-deep-venous-thrombus
#3
Gang Wu, Ruyi Xie, Xiaoli Zhang, John Morelli, Xu Yan, Xiaolei Zhu, Xiaoming Li
OBJECTIVES: The aim of this study was to evaluate the diagnostic performance of noncontrast magnetic resonance imaging utilizing sampling perfection with application optimized contrasts using different flip angle evolutions (SPACE) in detecting deep venous thrombus (DVT) of the lower extremity and evaluating clot burden. MATERIALS AND METHODS: This prospective study was approved by the institutional review board. Ninety-four consecutive patients (42 men, 52 women; age range, 14-87 years; average age, 52...
July 12, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28670055/effect-of-thrombus-aspiration-on-angiography-and-outcome-in-patients-undergoing-primary-coronary-angioplasty
#4
Praveen Chacko, Kesavapillai Jayaprakash, Kamarudheenkunju Jameelabeevi Raihanathul Misiriya, Suresh Madhavan, Vasantha Sudha Kumary, Narayanapillai Jayaprasad, Vaikathusseril Lembodaran Jayaprakash, Raju George
Thrombus exerts a major impact on the performance and outcome of primary and rescue interventions in acute ST-elevation myocardial infarction. Although the optimal treatment of thrombotic lesions is still controversial, thrombus aspiration provides an effective method to achieve successful reperfusion during primary angioplasty. We compared clinical and angiographic outcomes in 286 patients with acute ST-elevation myocardial infarction undergoing primary percutaneous transluminal coronary angioplasty (PTCA) and thrombus aspiration with those who underwent conventional PTCA without thrombus aspiration...
July 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28660560/jetstream-atherectomy-and-balloon-angioplasty-with-distal-embolic-protection-for-angio-seal%C3%A2-related-vascular-access-complications
#5
Mihir Barvalia, Mohammad Thawabi, Yassir Nawaz, Nishant Sethi, John Shao, Michael Amponsah, Gautam Visveswaran, Marc Cohen, Najam Wasty
Arteriotomy closure devices (ACDs) are routinely used for vascular closure during invasive cardiovascular procedures. They decrease time to hemostasis as well as length of stay. Major complications such as arterial ischemia and occlusion can be encountered in a minority of patients. We are describing a series of 3 patients with access site closure using Angio-Seal after coronary angiography who developed intermittent claudication within 2-3 weeks of follow-up. Access site thrombosis/stenosis in the CFA was found in all the three cases...
June 28, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28649956/the-ati-score-age-thrombotic-burden-index-of-microcirculatory-resistance-determined-during-primary-percutaneous-coronary-intervention-predicts-final-infarct-size-in-patients-with-st-elevation-myocardial-infarction-a-cardiac-magnetic-resonance-validation-study
#6
Giovanni Luigi De Maria, Mohammad Alkhalil, Mathias Wolfrum, Gregor Fahrni, Alessandra Borlotti, Lisa Gaughran, Sam Dawkins, Jeremy Langrish, Andrew Lucking, Robin Choudhury, Italo Porto, Filippo Crea, Erica Dall'Armellina, Keith Channon, Rajesh Kharbanda, Adrian Banning
AIMS: The age-thrombus score-index of microcirculatory resistance (ATI) score is a diagnostic tool able to predict suboptimal myocardial reperfusion before stenting, in patients with ST elevation myocardial infarction (STEMI). We aimed to validate the ATI score against cardiac magnetic resonance imaging (cMRI). METHODS AND RESULTS: The ATI score was calculated prospectively in 80 STEMI patients. cMRI was performed within 48 hours in all patients and in 50 patients at six months follow up to assess the extent of infarct size (IS%) and microvascular obstruction (MVO%)...
June 27, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28647998/-analysis-of-optical-coherence-tomography-of-early-and-very-late-stent-restenosis-after-drug-eluting-stent-implantation
#7
Z J Liu, B Shi, C C Deng, G X Xu, R Z Zhao, C Y Shen, Z L Wang, H L Liu
Objective: Using optical coherence tomography (OCT) to analyze the morphological characteristics of lesions between early in-stent restenosis (E-ISR) and very late in-stent restenosis (VL-ISR) after drug-eluting stents (DES) implantation. Methods: In 25 patients (DES) with ISR, OCT images were acquired before percutaneous coronary intervention (PCI), the morphological characteristics of E-ISR (<1 years, n=14) and VL-ISR (>3 years, n=11) were compared.The quantitative and qualitative analysis of the entire stent and the minimum lumen area (MLA) site were carried out respectively...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28615616/early-stage-mucinous-ovarian-adenocarcinoma-with-extensive-clotting-in-a-previously-healthy-young-female-patient-an-uncommon-presentation-of-a-relatively-uncommon-disease
#8
Suchin R Khanna, Brave Nguyen, Mahmoud Charif
BACKGROUND Mucinous ovarian adenocarcinoma is one of the less common epithelial cancers of the ovaries, and typically does not occur in younger women. Nearly all mucinous ovarian adenocarcinomas present with early-stage disease without significant sequelae of cancer, such as clotting. Anchoring bias is a common problem in medicine that has been shown to significantly affect physician decision-making. CASE REPORT We present the case of a 24-year-old healthy female Chinese immigrant with no significant past medical history, who presented with a subacute history of nonproductive cough and shortness of breath with exertion...
June 15, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28606888/neointima-and-neoatherosclerotic-characteristics-in-bare-metal-and-first-and-second-generation-drug-eluting-stents-in-patients-admitted-with-cardiovascular-events-attributed-to-stent-failure-an-optical-coherence-tomography-study
#9
Rodrigue Stettler, Jouke Dijkstra, Lorenz Räber, Ryo Torii, Yao-Jun Zhang, Antonis Karanasos, Shengnan Liu, Tom Crake, Steve Hamshere, Hector M Garcia-Garcia, Erhan Tenekecioglu, Muhiddin Ozkor, Stephan Windecker, Patrick W Serruys, Evelyn Regar, Anthony Mathur, Christos V Bourantas
AIMS: To assess neoatherosclerotic plaque morphology in bare metal (BMS) and 1st and 2nd generation drug eluting stents (DES) in patients presenting with an event attributed to stent failure. METHODS AND RESULTS: Thirty five patients (11 implanted with BMS, 13 with a 1st generation and 11 with a 2nd generation DES) admitted with an event due to stent failure who had neoatherosclerotic lesions on optical coherence tomography were included in the analysis. The lumen and stent borders were detected and the lipid and calcific tissue were identified in the neointima and their burden was estimated...
June 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28596039/assessment-of-aortic-wall-thrombus-predicts-outcomes-of-endovascular-repair-of-complex-aortic-aneurysms-using-fenestrated-and-branched-endografts
#10
Mauricio Ribeiro, Gustavo S Oderich, Thanila Macedo, Terri J Vrtiska, Jan Hofer, Julia Chini, Bernardo Mendes, Stephen Cha
OBJECTIVE: The goal of this study was to investigate the correlation between atherothrombotic aortic wall thrombus (AWT) and clinical outcomes in patients treated by fenestrated-branched endovascular aortic repair (F-BEVAR) and present a new classification system for assessment of AWT burden. METHODS: The clinical data of 301 patients treated for pararenal and thoracoabdominal aortic aneurysms (TAAAs) by F-BEVAR was reviewed. The study excluded 89 patients with extent I to III TAAA because of extensive laminated thrombus within the aneurysm sac...
June 5, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28591063/a-new-technique-for-lipid-core-plaque-detection-by-optical-coherence-tomography-for-prevention-of-peri-procedural-myocardial-infarction-a-case-report
#11
Yongcheol Kim, Muthukaruppan Gnanadesigan, Gijs van Soest, Thomas W Johnson
RATIONALE: Percutaneous coronary intervention (PCI) provides effective revascularization of atherosclerotic coronary arteries but the invasive nature of treatment can result in complications. PATIENT CONCERNS: A 53-year old man underwent coronary angiography due to chest pain with minimal ST-segment elevation in the inferior leads of the electrocardiogram. DIAGNOSIS: We proceeded directly to coronary angiography and delineated a moderate stenosis with haziness in the mid right coronary artery (RCA)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28562325/hsp-27-levels-and-thrombus-burden-relate-to-clinical-outcomes-in-patients-with-st-segment-elevation-myocardial-infarction
#12
Maozhou Tian, Lingmin Zhu, Hongyang Lin, Qiaoyan Lin, Peng Huang, Xiao Yu, Yanyan Jing
High thrombus burden, subsequent distal embolization, and myocardial no-reflow remain a large obstacle that may negate the benefits of urgent coronary revascularization in patients with ST-segment elevation myocardial infarction (STEMI). However, the biological function and clinical association of Hsp-27 with thrombus burden and clinical outcomes in patients with STEMI is not clear. Consecutive patients (n = 146) having STEMI undergoing primary percutaneous coronary intervention (pPCI) within 12 hours from the onset of symptoms were enrolled in this prospective study in the Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shangdong, P...
May 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/28554990/the-role-of-scube1-in-the-pathogenesis-of-no-reflow-phenomenon-presenting-with-st-segment-elevation-myocardial-infarction
#13
Hasan Ata Bolayır, Hakan Güneş, Tarık Kıvrak, Ömer Şahin, Dursun Akaslan, Recep Kurt, Aslı Bolayır, Oya İmadoğlu
OBJECTIVE: SCUBE1 [signal peptide-CUB (complement C1r/C1 s)-EGF (epidermal growth factor)-like domain-containing protein 1] might function as a novel platelet-endothelial adhesion molecule and play pathological roles in cardiovascular biology. Acute myocardial infarction is one of the most common causes of death in modern society. The concept of "no reflow" (NR) refers to a state of myocardial tissue hypoperfusion in the presence of a patent epicardial coronary artery. The main mechanisms of this phenomenon are thought to be high platelet activity and much thrombus burden...
May 24, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28525548/computational-fluid-dynamics-characterization-of-pulsatile-flow-in-central-and-sano-shunts-connected-to-the-pulmonary-arteries-importance-of-graft-angulation-on-shear-stress-induced-platelet-mediated-thrombosis
#14
Robert Ascuitto, Nancy Ross-Ascuitto, Martin Guillot, Carey Celestin
OBJECTIVES: Central (aorta) and Sano (right ventricle)-to-pulmonary artery (PA) shunts, palliative operations for infants with complex heart defects, can develop life-threatening thrombosis. We employed computational fluid dynamics (CFD) to study pulsatile flow in these shunts, with the goal to identify haemodynamic characteristics conducive to thrombus formation. METHODS: CFD, using the finite volume method with cardiac catheterization data, and computer simulations, based on angiography, were employed to determine flow-velocity field, wall shear stress (WSS) profile and oscillatory shear index (OSI)...
May 19, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28480772/cross-circulation-thrombectomy-with-use-of-a-stent-retriever-a-case-report
#15
Ali Sultan-Qurraie, Gregory Rozansky, John Andrew Cox, Marc Lazzaro
Introduction The efficacy of the endovascular treatment of acute ischemic stroke has been substantiated by several recent randomized clinical trials. While intra-arterial therapy has significantly evolved in recent years, anatomic cerebrovascular variants and disease burden can present challenges to timely recanalization. We present the first reported case of anterior-to-posterior mechanical clot retrieval with use of a stent retriever. Case description A 53-year-old man presented with basilar artery thrombosis...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28470135/a-decade-of-health-assessments-in-appalachia
#16
E Scott Sills, Xiang Li
Purpose The purpose of this paper is to describe standardized clinical process of care and quality performance metrics at Roane Medical Center (RMC) and compare data from 2005 to 2015. Design/methodology/approach Information was extracted from a nationwide sample of short-term acute care hospitals using the Hospital Quality Alliance (HQA) database, evaluating multiple parameters measured at RMC. HQA data from RMC were matched against state and national benchmarks; findings were also compared with similar reports from the same facility in 2005...
May 8, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28432262/quantitative-imaging-of-cerebral-thromboemboli-in-vivo-the-effects-of-tissue-type-plasminogen-activator
#17
Dong-Eog Kim, Jeong-Yeon Kim, Dawid Schellingerhout, Ju Hee Ryu, Su-Kyoung Lee, Sangmin Jeon, Ji Sung Lee, Jiwon Kim, Hee Jeong Jang, Jung E Park, Eo Jin Kim, Ick Chan Kwon, Cheol-Hee Ahn, Matthias Nahrendorf, Kwangmeyung Kim
BACKGROUND AND PURPOSE: Quantitative imaging for the noninvasive assessment of thrombolysis is needed to advance basic and clinical thrombosis-related research and tailor tissue-type plasminogen activator (tPA) treatment for stroke patients. We quantified the evolution of cerebral thromboemboli using fibrin-targeted glycol chitosan-coated gold nanoparticles and microcomputed tomography, with/without tPA therapy. METHODS: We injected thrombi into the distal internal carotid artery in mice (n=50)...
May 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28411920/neoadjuvant-targeted-molecular-therapy-before-renal-surgery
#18
REVIEW
Sumi Dey, Henry N Peabody, Sabrina L Noyes, Brian R Lane
Neoadjuvant targeted molecular therapy may benefit select patients with metastatic renal cell carcinoma. The primary use of this therapy in patients with metastatic disease is to reduce tumor burden, prevent distant metastasis, and increase overall survival. Neoadjuvant therapy may reduce tumor size and tumor complexity, facilitate partial nephrectomy rather than radical nephrectomy, downstage tumor thrombus facilitating thrombectomy, and make unresectable tumors resectable when applied to selected patients...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28400037/predictors-of-no-reflow-during-primary-angioplasty-for-acute-myocardial-infarction-from-medical-college-hospital-trivandrum
#19
Padmajan Sabin, Alummoottil George Koshy, Prabha Nini Gupta, Pattu Valappil Sanjai, Kunjukrishanpilla Sivaprasad, Praveen Velappan, Radhakrishnan Vellikat Velayudhan
BACKGROUND: Primary angioplasty (PCI) for acute myocardial infarction is associated with no-reflow phenomenon, in about 5-25% of cases. Here we analysed the factors predicting no reflow . METHODS: This was a case control study of consecutive patients with acute myocardial infarction who underwent Primary PCI from August 2014 to February 2015. RESULTS: Of 181 patients who underwent primary PCI, 47 (25.9%) showed an angiographic no-reflow phenomenon...
April 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28398633/intracranial-hemorrhage-in-a-patient-with-sub-massive-pulmonary-embolism-treated-with-ekosonic-endovascular-system-directed-thrombolysis
#20
Sarju Ganatra, Arjun Majithia, Yun-Ting Eric Yeh, Michael S Levy
Ultrasound-assisted catheter-directed thrombolysis therapy has emerged more recently as a management strategy for patients with intermediate risk pulmonary embolism and has shown promising results in clinical trials by early reversal of right ventricle dilation, reduced pulmonary hypertension, and decreased anatomic thrombus burden. This therapeutic strategy requires a small fraction of the systemic fibrinolytic dose and is therefore associated with a reduced bleeding risk. Although intracranial hemorrhage has not been reported in clinical trials, it is a possible complication...
April 11, 2017: Catheterization and Cardiovascular Interventions
keyword
keyword
19792
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"