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https://www.readbyqxmd.com/read/29455831/thoracoscopic-sympathectomy-for-refractory-electrical-storm-after-coronary-artery-bypass-grafting
#1
Brody Wehman, Michael Mazzeffi, Robert Chow, A Claire Watkins, Brittany Aicher, Si Pham, Whitney Burrows, Bradley Taylor
We report a patient with refractory electrical storm after coronary artery bypass grafting who was successfully treated with thoracoscopic sympathectomy. Cardiac arrest with ventricular tachycardia occurred on postoperative day 2, and the patient required emergency support with venoarterial extracorporeal membrane oxygenation. Frequent episodes of ventricular tachycardia prevented cardiac recovery and weaning from mechanical circulatory support. A percutaneous left stellate ganglion block initially demonstrated successful prevention of ventricular tachycardia, and definitive sympathetic denervation was achieved by a left thoracoscopic sympathectomy...
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29455018/acute-massive-pulmonary-thromboembolism-treated-by-selective-catheter-directed-thrombolysis
#2
Feng Hai, Chen Xueming, Zhang Zhiwen, Li Chenyu, Fang Jie, Zhang Zhe, Lian Lishan, Zhu Renming, Yu Hongzhi, Liu Bin
OBJECTIVE: To evaluate the safety and efficacy of selective catheter-directed thrombolysis in treating acute massive pulmonary thromboembolism (AMPTE). MATERIALS AND METHODS: Twenty-six AMPTE patients were enrolled between March 2010 and March 2013. A Uni*Fuse infusion system was inserted into the main pulmonary artery thrombus. The thrombolytic regimen included an intraoperative bolus injection of 250,000 IU urokinase, followed by continuous thrombolytic infusion of 5,000IU/kg...
February 15, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29449428/a-novel-piperidine-identified-by-stem-cell-based-screening-attenuates-pulmonary-arterial-hypertension-via-regulating-bmp2-and-ptgs2-levels
#3
Yanjiang Xing, Shuang Zhao, Qingxia Wei, Shiqiang Gong, Xin Zhao, Fang Zhou, Rafia Ai-Lamki, Daniel Ortmann, Mingxia Du, Roger Pedersen, Guangdong Shang, Shuyi Si, Nicholas W Morrell, Jun Yang
Genetic defects in bone morphogenetic protein type-II receptor (BMPRII) signalling and inflammation contribute to the pathogenesis of pulmonary arterial hypertension (PAH). The receptor is activated by BMP ligands, which also enhance BMPR2 transcription. A small molecule BMP upregulator with selectivity on vascular endothelium would represent a desirable therapeutic intervention for PAH.We assayed compounds identified in the screening of BMP2 upregulators for their ability to increase expression of Inhibitor of DNA binding 1 (Id1), using a dual reporter driven specifically in human embryonic stem cell (hESC)-derived endothelial cells (ECs)...
February 15, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29434623/chinese-expert-consensus-on-the-non-invasive-imaging-examination-pathways-of-stable-coronary-artery-disease
#4
Yun-Dai Chen, Wei-Yi Fang, Ji-Yan Chen, Zhan-Ming Fan, Chuan-Yu Gao, Jun-Bo Ge, Zuo-Xiang He, Yong Huo, Lang Li, Si-Jin Li, Xi-Lie Lu, Bin Lv, Ju-Ying Qian, Ya-Jun Shi, Zhu-Jun Shen, Jing Wang, Yi-Ning Wang, Lei Xu, Li Yang, Bo Yu, Mei Zhang, Jun-Jie Yang, Shu-Yang Zhang, Xiao-Li Zhang, Shi-Hua Zhao, Yang Zheng, Yu-Chi Han, Guang Zhi
No abstract text is available yet for this article.
January 2018: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29398151/differentiation-between-radiation-induced-brain-injury-and-glioma-recurrence-using-3d-pcasl-and-dynamic-susceptibility-contrast-enhanced-perfusion-weighted-imaging
#5
Yu-Lin Wang, Si Chen, Hua-Feng Xiao, Ying Li, Yan Wang, Gang Liu, Xin Lou, Lin Ma
PURPOSE: This study was performed to validate the efficacy of three-dimensional pseudocontinuous arterial spin labeling (pCASL) compared with dynamic susceptibility contrast-enhanced perfusion-weighted imaging (DSC-PWI) in distinguishing radiation-induced brain injury from glioma recurrence in patients with glioma. METHODS: Both 3D pCASL and DSC-PWI were performed using a 3.0 Tesla scanner in 69 patients with previously resected and irradiated glioma who displayed newly developed abnormal contrast-enhanced lesions...
February 1, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29392361/hepatic-pseudolymphoma-imaging-features-on-dynamic-contrast-enhanced-mri-and-diffusion-weighted-imaging
#6
Yang Zhou, XiaoLin Wang, Chen Xu, GuoFeng Zhou, MengSu Zeng, PengJu Xu
PURPOSE: To investigate dynamic contrast-enhanced (DCE) MR findings and diffusion-weighted imaging (DWI) characteristics of hepatic pseudolymphoma. MATERIALS AND METHODS: The MR data of 20 lesions in 14 patients with histopathologically proven hepatic pseudolymphoma were retrospectively analyzed. All patients underwent dynamic gadopentetate dimeglumine-enhanced MR imaging and DWI. Morphologic characteristics and signal features on T1- and T2-weighted images (T1WI, T2WI), and DCE pattern were qualitatively evaluated...
February 1, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29390556/treatment-of-longitudinal-stent-compression-under-intravenous-ultrasound-guidance-a-case-report
#7
Daoyuan Si, Hongliang Yang, Guohui Liu, Yaliang Tong, Yuquan He
RATIONALE: Longitudinal stent compression is a rare phenomenon, which has been increasingly reported in recent years. PATIENT CONCERNS: Following 2 stents implanted into the middle and proximal segments of the left anterior descending (LAD) artery, longitudinal stent compression occurred when a post-dilation balloon was introduced into the proximal stent opening. DIAGNOSE: The intravenous ultrasound (IVUS) examination revealed overlapping at the opening of the proximal stent and poor stent adherence...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29389472/acupuncture-therapy-improves-vascular-hemodynamics-and-stiffness-in-middle-age-hypertensive-individuals
#8
Nina Terenteva, Oksana Chernykh, Marcos A Sanchez-Gonzalez, Alexei Wong
Acupuncture (ACU) is becoming a more common practice among hypertensive individuals. However, the reported therapeutic effects of ACU in lowering brachial blood pressure (BP) are ambiguous. Therefore, evaluating more sensitive markers of arterial functioning might unveil the protective effects of ACU on hypertension. We examined the effects of an 8-week ACU therapy intervention on vascular hemodynamics and stiffness in middle-age hypertensive individuals. Participants were randomly assigned to either ACU (n = 23) or a control group (n = 22)...
February 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29387186/effect-of-recombinant-adeno-associated-virus-expressing-calcitonin-gene-related-peptide-on-chick-embryo-umbilical-artery-vasospasm-model
#9
Yongjie Yuan, Si Yang, Chao Li, Kan Xu, Jinlu Yu
In the present study, a recombinant adeno-associated virus vector containing the calcitonin gene related peptide gene (rAAV-CGRP) was constructed and the therapeutic effect of rAAV-CGRP on a chick umbilical artery vasospasm model induced by chick embryo allantoic cavity hemorrhage was investigated. Fresh specific pathogen-free fertilized chicken eggs were randomly divided into a rAAV-CGRP group, an empty vector virus (AAV) group, and a control group, with 24 eggs in each group. An umbilical arterial vasospasm model was established using a needle puncture method on a vein in the chorioallantoic membrane to induce a hemorrhage in the allantoic cavity of 11-day-old chicken embryonated eggs...
January 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29369947/hepatocellular-carcinoma-retrospective-evaluation-of-the-correlation-between-gadobenate-dimeglumine-enhanced-magnetic-resonance-imaging-and-pathologic-grade
#10
Xiuzhu Huang, Zebin Xiao, Yuyang Zhang, Na Lin, Meilian Xiong, Xinyao Huang, Qi Chen, Dairong Cao
OBJECTIVE: The aim of this study was to evaluate the usefulness of gadobenate dimeglumine-enhanced magnetic resonance imaging in characterizing the grade of hepatocellular carcinoma (HCC) using the signal intensity (SI) of the erector spinae as internal reference. MATERIALS AND METHODS: Clinical data of 40 patients (a total of 44 lesions) confirmed by pathology for HCC were retrospectively reviewed. Gadobenate dimeglumine-enhanced magnetic resonance imaging was performed in all patients, and SI of lesions (SIles), liver parenchyma around the lesions (SIhep), erector spinae (SImus) and standard deviation of SI of the surrounding noise (SDnoi) on nonenhanced T2WI, nonenhanced T1WI, and contrast-enhanced T1WI (in both arterial and hepatobiliary phase [AP and HBP]) were measured, respectively...
January 24, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29363240/magnesium-attenuates-endothelin-1-induced-vasoreactivity-and-enhances-vasodilation-in-mouse-pulmonary-arteries-modulation-by-chronic-hypoxic-pulmonary-hypertension
#11
Yun-Ping Mu, Qiu-Hong Huang, Jie-Ling Zhu, Si-Yi Zheng, Fu-Rong Yan, Xiao-Ling Zhuang, James S K Sham, Mo-Jun Lin
Pulmonary hypertension (PH) is characterized by enhanced vasoreactivity and sustained pulmonary vasoconstriction, arising from the aberrant Ca2+ homeostasis in pulmonary arterial smooth muscle cells. In addition to Ca2+ , magnesium, the most abundant intracellular divalent cation, also plays critical roles in many cellular processes that regulate cardiovascular functions. Recent findings suggested that magnesium regulates vascular functions by altering the vascular responses to vasodilator and vasoactive agonists, and affects endothelial function by modulating endothelium-dependent vasodilation in hypertension...
January 23, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29359262/numerical-investigation-of-the-effect-of-additional-pulmonary-blood-flow-on-patient-specific-bilateral-bidirectional-glenn-hemodynamics
#12
Biao Si, Bin Qiao, Guang Yang, Meng Zhu, Fengyu Zhao, Tongjian Wang, Na Li, Xiaopeng Ji, Guanghong Ding
The effect of additional pulmonary blood flow (APBF) on the hemodynamics of bilateral bidirectional Glenn (BBDG) connection was marginally discussed in previous studies. This study assessed this effect using patient-specific numerical simulation. A 15-year-old female patient who underwent BBDG was enrolled in this study. Patient-specific anatomy, flow waveforms, and pressure tracings were obtained using computed tomography, Doppler ultrasound technology, and catheterization, respectively. Computational fluid dynamic simulations were performed to assess flow field and derived hemodynamic metrics of the BBDG connection with various APBF...
January 22, 2018: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29354244/intraparenchymal-atypical-meningioma-in-basal-ganglia-region-in-a-child-case-report-and-literature-review
#13
Xiaowei Liu, Yuekang Zhang, Si Zhang, Chuanyuan Tao, Yan Ju
Intraparenchymal meningiomas without dural attachment are extremely rare, especially when they occur in basal ganglia region in child. An 8-year-old boy was admitted at our hospital, complaining of recurrent headache and vomiting for 3 months. Neurological examination showed impaired vision and mild paresis of the left extremities. Magnetic resonance imaging demonstrated a lesion located in the right basal ganglia region extending to superasellar cistern with solid, multiple cystic and necrotic components. Computed tomography revealed calcification within the mass...
January 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29335483/pilot-study-to-assess-visualization-and-therapy-of-inflammatory-mechanisms-after-vessel-reopening-in-a-mouse-stroke-model
#14
Ebba Beller, Laura Reuter, Anne Kluge, Christine Preibisch, Ute Lindauer, Alexei Bogdanov, Friederike Lämmer, Claire Delbridge, Kaspar Matiasek, Benedikt J Schwaiger, Tobias Boeckh-Behrens, Claus Zimmer, Alexandra S Gersing
After reperfusion therapy in stroke patients secondary inflammatory processes may increase cerebral damage. In this pilot study, effects of anti-inflammatory therapy were assessed in a middle cerebral artery occlusion (MCAO) mouse model after reperfusion. 1 hour after MCAO, the artery was reopened and tacrolimus or NaCl were administered intra-arterially. Perfusion-weighted (PWI) and diffusion-weighted images (DWI) were obtained by MRI during MCAO. DWI, T2- and T1-weighted images with and without Bis-5HT-DTPA administration were obtained 24 hours after MCAO...
January 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329654/uhplc-ltq-orbitrap-based-metabolomics-coupled-with-metabolomics-pathway-analysis-method-for-exploring-the-protection-mechanism-of-kudiezi-injection-in-a-rat-anti-ischemic-cerebral-reperfusion-damage-model
#15
Si-Yi Liu, Wei Cai, Fei Wang, Ying Liu, Zhan-Peng Shang, Xiu-Ping Zhang, Zi-Jian Wang, Jian-Qiu Lu, Jia-Yu Zhang
Kudiezi injection has been used extensively in the treatment of cerebrovascular and cardiovascular diseases. However, its therapeutic effects and underlying mechanism of action are not fully understood. The aim of the present study was to clarify the protective mechanisms of Kudiezi injection on cerebral ischemic injury, using metabolomics methods. Middle cerebral artery occlusion (MCAO) was introduced in rats to build the cerebral ischemic damage. UHPLC-LTQ-Orbitrap-based analytical method was established for analysis of the metabolites...
December 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/29325562/increased-epicardial-adipose-tissue-thickness-is-a-predictor-of-new-onset-diabetes-mellitus-in-patients-with-coronary-artery-disease-treated-with-high-intensity-statins
#16
Jeehoon Kang, Young-Chan Kim, Jin Joo Park, Sehun Kim, Si-Hyuck Kang, Young Jin Cho, Yeonyee E Yoon, Il-Young Oh, Chang-Hwan Yoon, Jung-Won Suh, Young-Seok Cho, Tae-Jin Youn, In-Ho Chae, Dong-Ju Choi
BACKGROUND: Statins are widely used for lipid lowering in patients with coronary artery disease (CAD), but increasing evidence indicates an association between statin use and new-onset of diabetes mellitus (NODM). Epicardial adipose tissue (EAT) refers to the visceral fat surrounding the heart, which is associated with metabolic diseases. We sought to determine the association between EAT thickness and NODM in CAD patients treated with high-intensity statins. METHODS: We conducted a retrospective medical record review of CAD patients treated with high-intensity statins for at least 6 months after percutaneous coronary intervention performed between January 2009 and June 2013 at Seoul National University Bundang Hospital...
January 11, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29310555/mechanical-circulatory-support-for-the-failing-fontan-conversion-to-assisted-single-ventricle-circulation-preliminary-observations
#17
Syed M Peer, Kristopher B Deatrick, Thomas J Johnson, Jonathan W Haft, Francis D Pagani, Richard G Ohye, Edward L Bove, Alvaro Rojas-Peña, Ming-Sing Si
BACKGROUND: Mechanical circulatory support (MCS) of a failing Fontan circulation remains challenging. We hypothesized that MCS can be provided by converting the Fontan circulation into a mechanically assisted single ventricle parallel circulation (MASVC). METHODS: A porcine model of functionally univentricular circulation was created under cardiopulmonary bypass (CPB) by performing an atrial septectomy, tricuspid valvectomy, and interrupting antegrade pulmonary blood flow...
January 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29273207/comparison-of-1-year-outcomes-of-triple-aspirin-clopidogrel-cilostazol-versus-dual-antiplatelet-therapy-aspirin-clopidogrel-placebo-after-implantation-of-second-generation-drug-eluting-stents-into-one-or-more-coronary-arteries-from-the-decrease-pci-trial
#18
Cheol Hyun Lee, Jong-Young Lee, Gyung-Min Park, Seung-Whan Lee, Hyun-Sook Kim, Young Jin Choi, Chang-Wook Nam, Jang Hyun Cho, Won-Yong Shin, Jae Bin Seo, Si Wan Choi, Jae-Hwan Lee, Pil-Ki Min, Sung-Ho Her, Pil Hyung Lee, Jung-Min Ahn, Duk-Woo Park, Soo-Jin Kang, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Seung-Jung Park
This study sought to evaluate the impact of triple antiplatelet therapy on clinical outcomes in patients treated with second-generation drug-eluting stents (DES) for coronary artery disease. There are limited data regarding the impact of triple antiplatelet therapy in patients who underwent implantation of second-generation DES. We planned to randomly assign 2,110 patients treated with second-generation DES to triple (aspirin, clopidogrel, and cilostazol) and dual (aspirin, clopidogrel, and placebo) antiplatelet therapy groups...
February 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29249595/is-emergency-transcatheter-hepatic-arterial-embolization-suitable-for-spontaneously-ruptured-hepatocellular-carcinoma-in-child-pugh-c-cirrhosis
#19
Wen-Zhe Fan, Ying-Qiang Zhang, Wang Yao, Yu Wang, Guo-Sheng Tan, Yong-Hui Huang, Jian-Yong Yang, Jia-Ping Li
PURPOSE: To evaluate the utility of emergent transcatheter arterial embolization for spontaneously ruptured hepatocellular carcinoma (HCC) in patients with Child-Pugh class C (CPC) liver cirrhosis presenting hemorrhagic shock. MATERIALS AND METHODS: A study of all 94 patients was retrospectively conducted from January 2006 to January 2016. Sixty patients underwent conservative treatment (control group) and 34 underwent embolization. RESULTS: Embolization provided better stabilization of hemodynamic status than conservative treatment (91...
December 14, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29245292/long-term-result-of-transcatheter-arterial-embolization-for-liver-hemangioma
#20
Xiaolei Liu, Zhiying Yang, Haidong Tan, Jia Huang, Li Xu, Liguo Liu, Shuang Si, Yongliang Sun
Transcatheter arterial embolization (TAE) is a method for the treatment of liver hemangioma, but fewer studies reported the long-term result.Retrospective study was conducted to liver hemangioma patients who received TAE. The inclusion criteria included the following: the period of follow-up was more than 5 years; and patients were followed up for less than 5 years, but received surgical treatment due to the enlargement of tumor or severe complications of TAE. The collected data included sex, age, size of the tumor, times of TAE, complications, period of follow-up, long-term result, and whether or not surgery was finally performed...
December 2017: Medicine (Baltimore)
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