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https://www.readbyqxmd.com/read/28411073/arterial-stiffness-and-elevated-left-ventricular-filling-pressure-in-patients-at-risk-for-the-development-or-a-previous-diagnosis-of-hf-a-subgroup-analysis-from-the-diast-chf-study
#1
Claus Lüers, Tobias Daniel Trippel, Sebastian Seeländer, Rolf Wachter, Gerd Hasenfuss, Ruhdja Lindhorst, Anna Bobenko, Kathleen Nolte, Burkert Pieske, Frank Edelmann
Left ventricular filling pressure (LVFP) is a marker for diastolic dysfunction and heart failure (HF) with preserved ejection fraction (pEF). The interaction between arterial stiffness (AS) and elevated LVFP has not been sufficiently investigated. In 257 patients with preserved left ventricular ejection fraction (mean age: 66 years, 53% female, mean left ventricular ejection fraction: 61%) and at least one cardiovascular risk factor (eg, hypertension and diabetes) for the development of HF or a previous diagnosis of HF, LVFP was estimated in accordance with the recommendations of the American Society of Echocardiography (elevated when E/e' ≥ 13, left atrial volume index ≥ 34 mL/m(2))...
March 27, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28407807/subclinical-inflammation-associated-with-prolonged-timp-1-upregulation-and-arterial-stiffness-after-gestational-diabetes-mellitus-a-hospital-based-cohort-study
#2
Tiina Vilmi-Kerälä, Anneli Lauhio, Taina Tervahartiala, Outi Palomäki, Jukka Uotila, Timo Sorsa, Ari Palomäki
BACKGROUND: Gestational diabetes mellitus (GDM) has significant implications for the future health of the mother. Some clinical studies have suggested subclinical inflammation and vascular dysfunction after GDM. We aimed to study whether concentrations of high-sensitivity C-reactive protein (hsCRP), tissue inhibitor of metalloproteinase-1 (TIMP-1), matrix metalloproteinase-8 (MMP-8) and -9, as well as values of arterial stiffness differ between women with and without a history of GDM a few years after delivery...
April 13, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28397006/acute-effect-of-stretching-one-leg-on-regional-arterial-stiffness-in-young-men
#3
Yosuke Yamato, Natsuki Hasegawa, Shumpei Fujie, Shigehiko Ogoh, Motoyuki Iemitsu
PURPOSE: Our previous study demonstrated that a single bout of stretching exercises acutely reduced arterial stiffness. We hypothesized that this acute vascular response is due to regional mechanical stimulation of the peripheral arteries. To test this hypothesis, we examined the effect of a single bout of passive one leg stretching on arterial stiffness, comparing the stretched and the non-stretched leg in the same subject. METHODS: Twenty-five healthy young men (20...
April 10, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28396534/aortic-brachial-arterial-stiffness-gradient-and-cardiovascular-risk-in-the-community-the-framingham-heart-study
#4
Teemu J Niiranen, Bindu Kalesan, Martin G Larson, Naomi M Hamburg, Emelia J Benjamin, Gary F Mitchell, Ramachandran S Vasan
A recent study reported that the aortic-brachial arterial stiffness gradient, defined as carotid-radial/carotid-femoral pulse wave velocity (PWV ratio), predicts all-cause mortality better than carotid-femoral pulse wave velocity (CFPWV) alone in dialysis patients. However, the prognostic significance of PWV ratio for cardiovascular disease (CVD) in the community remains unclear. Accordingly, we assessed the correlates and prognostic value of the PWV ratio in 2114 Framingham Heart Study participants (60±10 years; 56% women) free of overt CVD...
April 10, 2017: Hypertension
https://www.readbyqxmd.com/read/28395967/carotid-femoral-pulse-wave-velocity-assessed-by-ultrasound-a-study-with-echotracking-technology
#5
Mathieu Collette, Carlo Palombo, Carmela Morizzo, Sara Sbragi, Michaela Kozakova, Georges Leftheriotis
Described here is a new method for determination of carotid-femoral pulse wave velocity (PWV) based on arterial diameter waveform recording by an ultrasound system. The study was carried out on 120 consecutive patients. Carotid-femoral PWV was determined using a tonometric technique (PWVpp, PulsePen, DiaTecne, Milan, Italy) and an echotracking ultrasound system (PWVet, E-Track, Aloka, Tokyo, Japan). The relationship between PWVpp and PWVet was evaluated by linear regression and Bland-Altman analysis. There was excellent agreement between PWVet and PWVpp (Pearson's r = 0...
April 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28392041/arterial-stiffness-is-an-independent-predictor-for-albuminuria-progression-among-asians-with-type-2-diabetes-a-prospective-cohort-study
#6
Xiao Zhang, Serena Low, Chee Fang Sum, Subramaniam Tavintharan, Yeoh Lee Ying, Jianjun Liu, Na Li, Keven Anga, Simon Bm Lee, Wern Ee Tang, Su Chi Lim
AIM: Albuminuria progression has been associated with renal deterioration in type 2 diabetes (T2DM). Central arterial stiffness can aggravate systemic vasculopathy by propagating elevated systolic and pulse pressures forward, thereby accentuating global vascular injury. We aim to investigate whether central arterial stiffness is an independent predictor for albuminuria progression in a multi-ethnic T2DM Asian cohort in Singapore. METHODS: In a prospective cohort, 1012 T2DM patients were assessed at baseline and after a median follow-up of 3...
February 14, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28391885/relationship-between-changes-in-polyunsaturated-fatty-acids-and-aging-related-arterial-stiffness-in-overweight-subjects-50%C3%A2-years-or-older-over-a-3-year-period
#7
Seung Han Baek, Minkyung Kim, Minjoo Kim, Hye Jin Yoo, Ayoung Lee, Minjae Ji, Min Song, Jong Ho Lee
BACKGROUND: Although aging-related elastic arterial stiffness is an independent indicator of cardiovascular risk, the roles of polyunsaturated fatty acids in this condition remain uncertain. OBJECTIVE: This prospective study examined the relationships of aging, persist overweight and plasma fatty acids with arterial stiffening over 3 years. METHODS: We divided a cohort of 179 healthy, nonhypertensive subjects (aged ≥50 years) into 2 groups: a normal-weight group (18...
January 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28390406/the-evident-diet-quality-index-is-associated-with-cardiovascular-risk-and-arterial-stiffness-in-adults
#8
Carmela Rodríguez-Martin, Rosario Alonso-Domínguez, María C Patino-Alonso, Manuel A Gómez-Marcos, José A Maderuelo-Fernández, Carlos Martin-Cantera, Luis García-Ortiz, José I Recio-Rodríguez
BACKGROUND: We aimed to simplify information from food frequency questionnaires (FFQs) in a single parameter that allows for rapid identification of quality of patient diet and its relationship to cardiovascular risk and pulse wave velocity (PWV). METHODS: The sample from the EVIDENT study, consisting of 1553 subjects (aged 20-80 years) with no cardiovascular disease selected by random sampling among those attending primary care clinics, was used. The EVIDENT diet index (range 0-100) was calculated based on the results of a FFQ...
April 8, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28389287/the-effect-of-revascularization-on-the-hemodynamic-profile-of-patients-with-infrarenal-aortic-occlusion
#9
Christos Argyriou, Efstratios Georgakarakos, George S Georgiadis, Nikolaos Schoretsanitis, Miltos K Lazarides
OBJECTIVE: Patients undergoing revascularization for infrarenal aortic occlusion (IAO) have been reported to present improved survival rates compared to those treated conservatively. Aim of this study was to investigate the hemodynamic changes induced after revascularization for IAO, as expressed with pulse wave velocity (PWV), Augmentation Index (AIx), Augmentation Pressure (AP) and pulse wave reflection coefficient (RC). MATERIALS AND METHODS: Twelve patients underwent revascularization (9 aortobifemoral / aortobiiliac bypasses, 2 primary iliac stenting and 1 hybrid procedure of unilateral aortoiliac stenting and crossover bypass)...
April 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28386182/peripheral-arterial-stiffness-is-associated-with-higher-baseline-plasma-uric-acid-a-prospective-cohort-study
#10
Xiaohan Ding, Ping Ye, Xiaona Wang, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Yongyi Bai, Hongmei Wu
This prospective cohort study aimed at identifying association between uric acid (UA) and peripheral arterial stiffness. A prospective cohort longitudinal study was performed according to an average of 4.8 years' follow-up. The demographic data, anthropometric parameters, peripheral arterial stiffness (carotid-radial pulse-wave velocity, cr-PWV) and biomarker variables including UA were examined at both baseline and follow-up. Pearson's correlations were used to identify the associations between UA and peripheral arterial stiffness...
March 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28381875/masked-uncontrolled-hypertension-in-patients-on-maintenance-hemodialysis
#11
Wenjin Liu, Liang Wang, Zhuxing Sun, Xiurong Li, Jianmei Zhou, Chaoqing Gao, Hong Chu, Wei Fan, Youwei Bai, Junwei Yang
Masked uncontrolled hypertension (MUCH) has been proven to be associated with increased cardiovascular risk in the general population. We performed the current analysis to determine its prevalence in dialysis patients and its association with pulse wave velocity (PWV). From 368 participants of another cohort study, we selected 145 subjects with controlled predialysis blood pressure (BP). All subjects underwent ambulatory BP monitoring and PWV measurement. MUCH was defined as controlled predialysis BP with daytime BP⩾135/85 mm Hg (definition-1); total ambulatory BP⩾130/80 mm Hg (definition-2); and either daytime BP⩾135/85 mm Hg or nighttime BP⩾120/70 mm Hg (definition-3)...
April 6, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28381468/blood-pressure-and-arterial-stiffness-in-kenyan-adolescents-with-%C3%AE-thalassemia
#12
Anthony O Etyang, Christopher Khayeka-Wandabwa, Sailoki Kapesa, Esther Muthumbi, Emily Odipo, Marylene Wamukoya, Nicholas Ngomi, Tilahun Haregu, Catherine Kyobutungi, Metrine Tendwa, Johnstone Makale, Alex Macharia, J Kennedy Cruickshank, Liam Smeeth, J Anthony G Scott, Thomas N Williams
BACKGROUND: Recent studies have discovered that α-globin is expressed in blood vessel walls where it plays a role in regulating vascular tone. We tested the hypothesis that blood pressure (BP) might differ between normal individuals and those with α(+)thalassemia, in whom the production of α-globin is reduced. METHODS AND RESULTS: The study was conducted in Nairobi, Kenya, among 938 adolescents aged 11 to 17 years. Twenty-four-hour ambulatory BP monitoring and arterial stiffness measurements were performed using an arteriograph device...
April 5, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28379892/evaluation-of-arterial-stiffness-by-finger-toe-pulse-wave-velocity-optimization-of-signal-processing-and-clinical-validation
#13
Hasan Obeid, Hakim Khettab, Louise Marais, Magid Hallab, Stéphane Laurent, Pierre Boutouyrie
BACKGROUND: Carotid-femoral pulse wave velocity (PWV) (cf-PWV) is the gold standard for measuring aortic stiffness. Finger-toe PWV (ft-PWV) is a simpler noninvasive method for measuring arterial stiffness. Although the validity of the method has been previously assessed, its accuracy can be improved. ft-PWV is determined on the basis of a patented height chart for the distance and the pulse transit time (PTT) between the finger and the toe pulpar arteries signals (ft-PTT). METHOD: The objective of the first study, performed in 66 patients, was to compare different algorithms (intersecting tangents, maximum of the second derivative, 10% threshold and cross-correlation) for determining the foot of the arterial pulse wave, thus the ft-PTT...
April 4, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28376407/baseline-predictors-of-aortic-stiffness-progression-among-multi-ethnic-asians-with-type-2-diabetes
#14
Mei Chung Moh, Chee Fang Sum, Subramaniam Tavintharan, Keven Ang, Simon Biing Ming Lee, Wern Ee Tang, Su Chi Lim
BACKGROUND AND AIMS: This 3-year prospective study aimed to identify baseline parameters that predicted the progression of carotid-femoral pulse wave velocity (cf-PWV), which was used to evaluate aortic stiffness, among Singapore's multi-ethnic Asians with type 2 diabetes (T2DM). METHODS: The cf-PWV was measured by the gold-standard tonometry method in 994 T2DM subjects at baseline and follow-up. The annual rate of cf-PWV change was calculated, and individuals above the 90(th) percentile with rate≥1...
January 27, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28365237/contributions-of-aortic-pulse-wave-velocity-and-backward-wave-pressure-to-variations-in-left-ventricular-mass-are-independent-of-each-other
#15
Hamza Bello, Gavin R Norton, Imraan Ballim, Carlos D Libhaber, Pinhas Sareli, Angela J Woodiwiss
Aortic pulse wave velocity (PWV) and backward waves, as determined from wave separation analysis, predict cardiovascular events beyond brachial blood pressure. However, the extent to which these aortic hemodynamic variables contribute independent of each other is uncertain. In 749 randomly selected participants of African ancestry, we therefore assessed the extent to which relationships between aortic PWV or backward wave pressures (Pb) (and hence central aortic pulse pressure [PPc]) and left ventricular mass index (LVMI) occur independent of each other...
March 14, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28364019/arterial-viscoelasticity-role-in-the-dependency-of-pulse-wave-velocity-on-heart-rate-in-conduit-arteries
#16
Hanguang Xiao, Isabella Tan, Mark Butlin, Decai Li, Alberto P Avolio
Experimental investigations have established that the stiffness of large arteries has a dependency on acute heart rate (HR) changes. However, possible underlying mechanisms inherent in this HR dependency have not been well established. This study aimed to explore a plausible viscoelastic mechanism by which HR exerts an influence on arterial stiffness. A multi-segment transmission line model of the human arterial tree incorporating fractional viscoelastic components in each segment was used to investigate the effect of varying fractional order parameter (α) of viscoelasticity on the dependence of aortic arch to femoral artery pulse wave velocity (afPWV) on HR...
March 31, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28360227/increased-arterial-stiffness-is-an-independent-predictor-of-renal-function-decline-in-patients-with-type-2-diabetes-mellitus-younger-than-60%C3%A2-years
#17
Nikolaos Fountoulakis, Chiraag Thakrar, Kishan Patel, Giancarlo Viberti, Luigi Gnudi, Janaka Karalliedde
BACKGROUND: The objective of this study was to evaluate whether aortic pulse wave velocity (Ao-PWV) predicts estimated glomerular filtration rate (eGFR) decline in patients with type 2 diabetes mellitus. METHODS AND RESULTS: This prospective single-center cohort study investigated 211 type 2 diabetes mellitus patients with eGFR ≥45 mL/min with a baseline mean age of 60.1 years (range, 30-82 years). The mean±SD baseline eGFR was 85±26.1 mL/min. We divided the cohort into 2 groups above (n=117, "older") and below (n=94, "younger") the mean age to evaluate whether Ao-PWV predicted progression of kidney disease differentially in older and younger patients...
March 30, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28359657/association-of-vitamin-d-metabolites-with-arterial-function-in-the-hemodialysis-fistula-maturation-study
#18
Adriana J van Ballegooijen, Leila Zelnick, Andrew N Hoofnagle, Naomi M Hamburg, Cassiane Robinson-Cohen, Prabir Roy-Chaudhury, Alfred K Cheung, Yan-Ting E Shiu, Ian H de Boer, Jonathan Himmelfarb, Gerald Beck, Peter B Imrey, John W Kusek, Bryan Kestenbaum
BACKGROUND: Disturbances in vitamin D metabolism are common in patients with end-stage renal disease and may contribute to vascular dysfunction. STUDY DESIGN: Cross-sectional. SETTING & PARTICIPANTS: We evaluated 558 of 602 participants at baseline of the Hemodialysis Fistula Maturation (HFM) Study, a 7-center prospective cohort study of a cohort of patients with chronic kidney disease awaiting arteriovenous fistula (AVF) creation surgery...
March 27, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28350575/influence-of-carotid-atherosclerotic-plaques-on-pulse-wave-assessment-with-arterial-tonometry
#19
Andrea Grillo, Giulia Simon, Paolo Salvi, Matteo Rovina, Corrado Baldi, Ilaria Prearo, Stella Bernardi, Bruno Fabris, Andrea Faini, Gianfranco Parati, Moreno Bardelli, Renzo Carretta
OBJECTIVE: Aortic stiffness and central pressure measurements have become increasingly important for the overall estimation of cardiovascular risk. The aim of this study is to verify whether the presence of stenosis in the carotid arteries due to atherosclerotic plaques may induce a bias in the measurement of carotid-femoral pulse wave velocity (PWV) and in the analysis of central pulse waveform variables assessed by carotid tonometry. METHODS: Eighty-four patients (age: 67...
March 27, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28339088/sclerostin-is-a-possible-candidate-marker-of-arterial-stiffness-results-from-a-cohort-study-in-catania
#20
Agostino Gaudio, Valerio Fiore, Rosario Rapisarda, Maria Helga Sidoti, Anastasia Xourafa, Antonino Catalano, Giovanni Tringali, Luca Zanoli, Salvatore Santo Signorelli, Carmelo Erio Fiore
Osteoporosis and cardiovascular disease are worldwide public health issues. Recent evidence indicates a possible role of the canonical Wnt/β-catenin signalling pathway as a common mediator between these two diseases. The aim of the present study was to investigate the relationship between serum concentrations of sclerostin and Dkk1, two extracellular inhibitors of Wnt/β-catenin signalling, with carotid intima-media thickness (CIMT) and with arterial stiffness, evaluated by measuring the pulse wave velocity (PWV) in an ambulatory population of adults...
March 24, 2017: Molecular Medicine Reports
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