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https://www.readbyqxmd.com/read/28651333/responses-of-lichen-communities-to-18%C3%A2-years-of-natural-and-experimental-warming
#1
Juha M Alatalo, Annika K Jägerbrand, Shengbin Chen, Ulf Molau
Background and Aims: Climate change is expected to have major impacts on high alpine and arctic ecosystems in the future, but empirical data on the impact of long-term warming on lichen diversity and richness are sparse. This study report the effects of 18 years of ambient and experimental warming on lichens and vascular plant cover in two alpine plant communities, a dry heath with sparse canopy cover (54 %) and a mesic meadow with a more developed (67 %) canopy cover, in sub-arctic Sweden...
June 22, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28650566/immediate-vs-delayed-initiation-of-the-levonorgestrel-releasing-intrauterine-system-following-medical-termination-of-pregnancy-one-year-continuation-rates-a-randomised-controlled-trial
#2
Riina Korjamo, Maarit Mentula, Oskari Heikinheimo
OBJECTIVE: To assess the 1-year continuation rates and new pregnancies following immediate vs. delayed insertion of the levonorgestrel-releasing intrauterine system (LNG-IUS) after medical termination of pregnancy (MTOP) of up to 20 weeks of gestation. DESIGN: A randomised controlled trial. SETTING: Helsinki University Hospital, Finland, Jan 2013-Dec 2014. POPULATION: 267 women requesting MTOP and planning LNG-IUS for post-MTOP contraception...
June 26, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28650440/probing-dark-excitons-in-atomically-thin-semiconductors-via-near-field-coupling-to-surface-plasmon-polaritons
#3
You Zhou, Giovanni Scuri, Dominik S Wild, Alexander A High, Alan Dibos, Luis A Jauregui, Chi Shu, Kristiaan De Greve, Kateryna Pistunova, Andrew Y Joe, Takashi Taniguchi, Kenji Watanabe, Philip Kim, Mikhail D Lukin, Hongkun Park
Transition metal dichalcogenide (TMD) monolayers with a direct bandgap feature tightly bound excitons, strong spin-orbit coupling and spin-valley degrees of freedom. Depending on the spin configuration of the electron-hole pairs, intra-valley excitons of TMD monolayers can be either optically bright or dark. Dark excitons involve nominally spin-forbidden optical transitions with a zero in-plane transition dipole moment, making their detection with conventional far-field optical techniques challenging. Here, we introduce a method for probing the optical properties of two-dimensional materials via near-field coupling to surface plasmon polaritons (SPPs)...
June 26, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28650214/distinct-dna-methylation-profiles-in-bone-and-blood-of-osteoporotic-and-healthy-postmenopausal-women
#4
Sjur Reppe, Tonje G Lien, Yi-Hsiang Hsu, Vigdis T Gautvik, Ole K Olstad, Rona Yu, Hege G Bakke, Robert Lyle, Marianne K Kringen, Ingrid K Glad, Kaare M Gautvik
DNA methylation affects expression of associated genes and may contribute to the missing genetic effects from genome-wide association studies of osteoporosis. To improve insight into the mechanisms of postmenopausal osteoporosis, we combined transcript profiling with DNA methylation analyses in bone. RNA and DNA were isolated from 84 bone biopsies of postmenopausal donors varying markedly in bone mineral density (BMD). In all, 2529 CpGs in the top 100 genes most significantly associated with BMD were analyzed...
June 26, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/28650155/probing-interface-defects-in-top-gated-mos2-transistors-with-impedance-spectroscopy
#5
Peng Zhao, Angelica Azcatl, Yuri Y Gomeniuk, Pavel Bolshakov, Michael Schmidt, Stephen J McDonnell, Christopher L Hinkle, Paul K Hurley, Robert M Wallace, Chadwin Young
The electronic properties of the HfO2/MoS2 interface were investigated using multi-frequency capacitance-voltage (C-V) and current-voltage characterization of top gated MoS2 metal oxide semiconductor field effect transistors. The analysis was performed on few layer (5 - 10) MoS2 MOSFETs fabricated using photolithographic patterning with 13 nm and 8 nm HfO2 gate oxide layers formed by atomic layer deposition after in-situ UV-O3 surface functionalization. The impedance response of the HfO2/MoS2 gate stack indicates the existence of specific defects at the interface, which exhibited either a frequency dependent distortion similar to conventional Si MOSFETs with unpassivated silicon dangling bonds, or a frequency dispersion over the entire voltage range corresponding to depletion of the HfO2/MoS2 surface, consistent with interface traps distributed over a range of energy levels...
June 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28650023/ligand-induced-conformational-preorganization-of-loops-of-c-myc-g-quadruplex-dna-and-its-implications-in-structure-specific-drug-design
#6
S Harikrishna, Saikiran Kotaru, P I Pradeepkumar
Stabilization of a G-quadruplex (G4) DNA structure in the proto-oncogene c-MYC using small molecule ligands has emerged as an attractive strategy for the development of anticancer therapeutics. To understand the subtle structural changes in the G4 structure upon ligand binding, molecular dynamics (MD) simulations of c-MYC G4 DNA were carried out in a complex with six different potent ligands: 3AQN, 6AQN, 3APN, 360A, Nap-Et, and Nap-Pr. The results show that the ligands 3AQN, 6AQN, 3APN, and 360A stabilize the G4 structure by making stacking interactions with the top quartet...
June 26, 2017: Molecular BioSystems
https://www.readbyqxmd.com/read/28649975/fabrication-of-algan-nanorods-with-different-al-compositions-for-emission-enhancement-in-uv-range
#7
Jiangping Dai, Bin Liu, Zhe Zhuang, Guotang He, Ting Zhi, Tao Tao, Qingjun Xu, Yi Li, Haixiong Ge, Zili Xie, Rong Zhang
Highly ordered AlxGa1-xN nanorods with varied aluminum alloy compositions (0.18≤x≤0.8) are fabricated with nanoimprint lithography and top-down dry etching techniques. And the structural properties and morphology are obtained by scanning electron microscopy(SEM) and transmission electron microscopy(TEM). Compared with as-grown AlGaN samples, nanorod samples reveal outstanding optical performance on account of strain releasing and light extraction enhancement. Through Raman scattering and Cathodeluminescence measurements, it has been observed clear red-shifts of E2h modes and near band edge emission(NBE) peaks of AlGaN nanorods compared to the planar ones, indicating the residual strain releasing after nano-fabrication...
June 26, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28649940/top-rated-amee-mededpublish-papers-march-2017
#8
(no author information available yet)
No abstract text is available yet for this article.
July 2017: Medical Teacher
https://www.readbyqxmd.com/read/28649900/sweet-cheeks-vs-pea-brain-embodiment-valence-and-task-all-influence-the-emotional-salience-of-language
#9
Erik M Benau, Sabrina C Gregersen, Paul D Siakaluk, Aminda J O'Hare, Eric K Johnson, Ruth Ann Atchley
Previous research has found that more embodied insults (e.g. numbskull) are identified faster and more accurately than less embodied insults (e.g. idiot). The linguistic processing of embodied compliments has not been well explored. In the present study, participants completed two tasks where they identified insults and compliments, respectively. Half of the stimuli were more embodied than the other half. We examined the late positive potential (LPP) component of event-related potentials in early (400-500 ms), middle (500-600 ms), and late (600-700 ms) time windows...
June 26, 2017: Cognition & Emotion
https://www.readbyqxmd.com/read/28649883/middle-down-proteomics-a-still-unexploited-resource-for-chromatin-biology
#10
Simone Sidoli, Benjamin A Garcia
Introduction Analysis of histone post-translational modifications (PTMs) by mass spectrometry (MS) has become a fundamental tool for the characterization of chromatin composition and dynamics. Histone PTMs benchmark several biological states of chromatin, including regions of active enhancers, active/repressed gene promoters and damaged DNA. These complex regulatory mechanisms are often defined by combinatorial histone PTMs; for instance, active enhancers are commonly occupied by both marks H3K4me1 and H3K27ac...
June 26, 2017: Expert Review of Proteomics
https://www.readbyqxmd.com/read/28649798/electrochemical-exfoliation-of-layered-black-phosphorous-to-phosphorene
#11
Martin Pumera
Among 2D materials that recently have attracted enormous interest, black phosphorous (BP) is gaining a rising popularity due to its tunable band gap structure strongly correlated to the thickness and which can enable its use in optoelectronic and electronic applications. It is therefore important to provide a facile and scalable methodology to prepare single or few-layer BP nanosheets. We propose here a simple and fast top-down method to exfoliate a BP crystal into nanosheets of reduced thickness using electrochemistry...
June 26, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28649725/high-throughput-screening-identifies-novel-cell-cycle-arresting-small-molecule-enhancers-of-transient-protein-expression
#12
Hermann-Josef Meyer, Rebecca Turincio, Shirley Ng, Juan Li, Blair Wilson, Pamela Chan, Mark Zak, Dorothea Reilly, Maureen H Beresini, Athena W Wong
Transient gene expression in mammalian cells is an efficient process for producing recombinant proteins for various research applications to support large molecule therapeutics development. For the first time, we report a high throughput small molecule (SM) screen to identify novel compounds that increase antibody titers after polyethylenimine (PEI) transient transfection of a HEK293 cell line. After screening 31,413 SMs in a 50 μL scaled-down process, we validated 164 SMs to improve yields by up to 2-fold...
June 26, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28649614/integrated-molecular-landscape-of-parkinson-s-disease
#13
C J H M Klemann, G J M Martens, M Sharma, M B Martens, O Isacson, T Gasser, J E Visser, G Poelmans
Parkinson's disease is caused by a complex interplay of genetic and environmental factors. Although a number of independent molecular pathways and processes have been associated with familial Parkinson's disease, a common mechanism underlying especially sporadic Parkinson's disease is still largely unknown. In order to gain further insight into the etiology of Parkinson's disease, we here conducted genetic network and literature analyses to integrate the top-ranked findings from thirteen published genome-wide association studies of Parkinson's disease (involving 13...
2017: NPJ Parkinson's Disease
https://www.readbyqxmd.com/read/28649486/constrictive-pericarditis-induced-shunting-through-a-pfo-persistence-despite-pericardiectomy
#14
Emily Schuiteman, Thomas Verrill, Nader Mina, Bhavinkumar Dalal
A patent foramen ovale (PFO) is found in around 25-30% of patients. The discovery is often made only on autopsy, as most PFOs are clinically silent and any inter-atrial blood exchange typically shunts from the left to right heart [1]. Thus, when a patient presents with hypoxic respiratory failure, concern for presence of a PFO is rarely at the top of the differential. However, in the setting of elevated right heart pressures, PFOs can become of great hemodynamic importance and can lead to deadly complications, including right to left shunting and refractory hypoxic respiratory failure...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28649377/a-bibliometric-analysis-of-the-citation-classics-of-acute-appendicitis
#15
REVIEW
Manvydas Varzgalis, Dermot J Bowden, Ciaran K Mc Donald, Michael J Kerin
INTRODUCTION: Acute appendicitis is one of the most commonly encountered emergency surgical conditions. An understanding of the most highly cited research works in this field is key to good evidence based clinical practice. AIMS: To perform a bibliometric analysis on the 100 most frequently cited articles in the field of acute appendicitis. METHODS: The database of the Institute for Scientific Information (ISI) Web of Science Expanded citation index was searched to identify the 100 most frequently cited articles in the field of acute appendicitis...
July 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28649351/new-insights-into-the-genetic-composition-and-phylogenetic-relationship-of-wolves-and-dogs-in-the-iberian-peninsula
#16
Ana Elisabete Pires, Isabel R Amorim, Carla Borges, Fernanda Simões, Tatiana Teixeira, Andreia Quaresma, Francisco Petrucci-Fonseca, José Matos
This study investigates the gene pool of Portuguese autochthonous dog breeds and their wild counterpart, the Iberian wolf subspecies (Canis lupus signatus), using standard molecular markers. A combination of paternal and maternal molecular markers was used to investigate the genetic composition, genetic differentiation and genetic relationship of native Portuguese dogs and the Iberian wolf. A total of 196 unrelated dogs, including breed and village dogs from Portugal, and other dogs from Spain and North Africa, and 56 Iberian wolves (wild and captive) were analyzed for nuclear markers, namely Y chromosome SNPs, Y chromosome STR loci, autosomal STR loci, and a mitochondrial fragment of the control region I...
June 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28649332/behavioral-evidence-of-hunting-and-foraging-techniques-by-a-top-predator-suggests-the-importance-of-scavenging-for-preadults
#17
Antoni Margalida, MªÀngels Colomer, Roberto Sánchez, Francisco Javier Sánchez, Javier Oria, Luis Mariano González
Scavenging may be a regular feeding behavior for some facultative raptor species occupying low quality habitats and/or with little experience in hunting techniques. However, its importance has been largely underestimated due to methodological limitations in identifying the real proportion in the diet. Here, through direct observations, we assessed the hunting and foraging success of the threatened Spanish imperial eagle Aquila adalberti determining the influence of age, sex, breeding status, habitat quality, prey type, and landscape characteristics...
June 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28649042/worldwide-human-daily-intakes-of-bisphenol-a-bpa-estimated-from-global-urinary-concentration-data-2000-2016-and-its-risk-analysis
#18
Ri-Ping Huang, Ze-Hua Liu, Su-Fen Yuan, Hua Yin, Zhi Dang, Ping-Xiao Wu
To evaluate BPA's potential risk to health, it is important to know human daily intake. This study describes a simple but effective method to estimate the levels of human BPA intake among four different populations based on urinary concentration data. Nationally, of the 30 countries examined, the top ten countries for adult intake were Italy, Sweden, Denmark, France, Cyprus, Australia, Israel, Ghana, Jamaica, and Belgium. When the urinary excretion sample size was large enough and over 1000, it was found that the national estimated BPA daily intakes in the child group among countries, showed a good linear relationship with those of their corresponding adult group...
June 22, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28648891/implications-of-the-vienna-integrated-model-of-art-perception-for-art-based-interventions-in-clinical-populations-comment-on-move-me-astonish-me-delight-my-eyes-and-brain-the-vienna-integrated-model-of-top-down-and-bottom-up-processes-in-art-perception-vimap
#19
https://www.readbyqxmd.com/read/28648889/mapping-between-fmri-responses-to-movies-and-their-natural-language-annotations
#20
REVIEW
Kiran Vodrahalli, Po-Hsuan Chen, Yingyu Liang, Christopher Baldassano, Janice Chen, Esther Yong, Christopher Honey, Uri Hasson, Peter Ramadge, Kenneth A Norman, Sanjeev Arora
Several research groups have shown how to map fMRI responses to the meanings of presented stimuli. This paper presents new methods for doing so when only a natural language annotation is available as the description of the stimulus. We study fMRI data gathered from subjects watching an episode of BBCs Sherlock (Chen et al., 2017), and learn bidirectional mappings between fMRI responses and natural language representations. By leveraging data from multiple subjects watching the same movie, we were able to perform scene classification with 72% accuracy (random guessing would give 4%) and scene ranking with average rank in the top 4% (random guessing would give 50%)...
June 22, 2017: NeuroImage
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