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https://www.readbyqxmd.com/read/28922848/aggressive-behavior-in-silent-subtype-iii-pituitary-adenomas-may-depend-on-suppression-of-local-immune-response-a-whole-transcriptome-analysis
#1
Timothy E Richardson, Zhong-Jian Shen, Mohammed Kanchwala, Chao Xing, Alexander Filatenkov, Ping Shang, Samuel Barnett, Zahidur Abedin, James S Malter, Jack M Raisanen, Dennis K Burns, Charles L White, Kimmo J Hatanpaa
Silent subtype III pituitary adenomas (SS-3) are clinically nonfunctional adenomas that are more aggressive in terms of invasion and risk of recurrence than their conventional null cell counterparts. We previously showed that these tumors can be distinguished by immunohistochemistry based on the identification of a markedly enlarged and fragmented Golgi apparatus. To understand the molecular correlates of differential aggressiveness, we performed whole transcriptome sequencing (RNAseq) on 4 SS-3 and 4 conventional null cell adenomas...
October 1, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28922564/obesity-alters-b-cell-and-macrophage-populations-in-brown-adipose-tissue
#2
Kristin R Peterson, David K Flaherty, Alyssa H Hasty
OBJECTIVE: The prevalence of obesity continues to rise, and it is understood that regulation of white adipose tissue (WAT) function is important to systemic metabolic homeostasis. Immune cells play a central role in the maintenance of WAT, and their compositions change in number and inflammatory phenotype with the progression of obesity. Because of its energy-burning capabilities, brown adipose tissue (BAT) has become a focus of obesity research. Although novel studies have focused on the function of brown adipocytes in thermogenesis, the tissue as a whole has not been immunologically characterized...
September 18, 2017: Obesity
https://www.readbyqxmd.com/read/28922518/accelerated-epithelialization-and-improved-wound-healing-metrics-in-porcine-full-thickness-wounds-transplanted-with-full-thickness-skin-micrografts
#3
Christina L Rettinger, John L Fletcher, Anders H Carlsson, Rodney K Chan
Split-thickness skin grafting (STSG) is the current gold standard for treatment of extensive burn and traumatic skin injuries. However, STSG is limited by donor-site morbidity and availability, and often leads to scarring and wound contracture. Furthermore, these thin grafts lack dermal elements such as nerves and adnexa which are important in recapitulating normal skin function. Methods of fractional skin replacement either as minced STSGs or microscopic skin tissue columns (MSTCs) have been proposed, though these techniques have not been fully-characterized and lack evidence of regenerated adnexal structures...
September 18, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28922374/fractional-laser-exposure-induces-neutrophil-infiltration-n1-phenotype-into-the-tumor-and-stimulates-systemic-anti-tumor-immune-response
#4
Masayoshi Kawakubo, Shadmehr Demehri, Dieter Manstein
BACKGROUND: Ablative fractional photothermolysis (aFP) using a CO2 laser generates multiple small diameter tissue lesions within the irradiation field. aFP is commonly used for a wide variety of dermatological indications, including treatment of photodamaged skin and dyschromia, drug delivery and modification of scars due to acne, surgical procedures and burns. In this study we explore the utility of aFP for treating oncological indications, including induction of local tumor regression and inducing anti-tumor immunity, which is in marked contrast to current indications of aFP...
2017: PloS One
https://www.readbyqxmd.com/read/28922022/implementing-a-collaborative-coaching-intervention-for-professionals-providing-care-to-children-and-their-families-an-exploratory-study
#5
Sandy K Tatla, Dori Howard, Alda Antunes Silvestre, Stacey Burnes, Meghan Husson, Tal Jarus
The growing complexity of healthcare requires family and interprofessional partnerships to deliver effective care. Interprofessional coaching can enhance family-centred practice and collaboration. The purpose of this study was to explore the acceptability and feasibility of collaborative coaching training to improve family centredness within acute paediatric rehabilitation. Using a participatory action design, service providers (SPs; n = 36) underwent a 6-month coaching programme involving coaching workshops, learning triads, and tailored sessions with a licensed coach...
September 18, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28921655/fast-dynamic-ventilation-mri-of-hyperpolarized-129-xe-using-spiral-imaging
#6
Ozkan Doganay, Tahreema N Matin, Anthony Mcintyre, Brian Burns, Rolf F Schulte, Fergus V Gleeson, Daniel Bulte
PURPOSE: To develop and optimize a rapid dynamic hyperpolarized (129) Xe ventilation (DXeV) MRI protocol and investigate the feasibility of capturing pulmonary signal-time curves in human lungs. THEORY AND METHODS: Spiral k-space trajectories were designed with the number of interleaves Nint  = 1, 2, 4, and 8 corresponding to voxel sizes of 8 mm, 5 mm, 4 mm, and 2.5 mm, respectively, for field of view = 15 cm. DXeV images were acquired from a gas-flow phantom to investigate the ability of Nint  = 1, 2, 4, and 8 to capture signal-time curves...
September 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28920800/cutaneous-t-cell-lymphoma-with-lymph-node-metastasis-in-an-adult-addax-addax-nasomaculatus
#7
Zoltan S Gyimesi, Roy B Burns, Sheryl Coutermarsh-Ott, Chris A Schiller, Rita McManamon
A 13-yr-old male addax (Addax nasomaculatus) presented with locally extensive alopecia, slight erythema, and skin thickening on the medial aspect of the left rear leg between the stifle and tarsus. Cutaneous T-cell lymphoma was diagnosed after histopathology and immunohistochemical staining of representative skin-punch biopsies. No treatment was elected, and the addax was euthanized 3 yr later because of poor body condition, chronic dental disease, and confirmed spread of lymphoma to other cutaneous locations...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28920168/the-online-measured-black-carbon-aerosol-and-source-orientations-in-the-nam-co-region-tibet
#8
Xin Zhang, Jing Ming, Zhongqin Li, Feiteng Wang, Guoshuai Zhang
Equivalent black carbon (eBC) mass concentrations were measured by an aethalometer (AE-31) in the Nam Co, central Tibet from 2010 to 2014. Different from previous filter-sampling studies (Ming et al., J Environ Sci 22(11):1748-1756, 2010; Zhao et al., Environ Sci Pollut Res 20:5827-5838, 2013), the first high-resolution online eBC measurement conducted in central Tibet is reported here, allowing to discuss the diurnal variations as well as seasonal variabilities of eBC. Average daily eBC concentration was 74 ± 50 ng/m(3), reflecting a global background level...
September 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28920065/the-influence-of-sex-steroid-hormones-on-the-response-to-trauma-and-burn-injury
#9
REVIEW
K Al-Tarrah, N Moiemen, J M Lord
Trauma and related sequelae result in disturbance of homeostatic mechanisms frequently leading to cellular dysfunction and ultimately organ and system failure. Regardless of the type and severity of injury, gender dimorphism in outcomes following trauma have been reported, with females having lower mortality than males, suggesting that sex steroid hormones (SSH) play an important role in the response of body systems to trauma. In addition, several clinical and experimental studies have demonstrated the effects of SSH on the clinical course and outcomes following injury...
2017: Burns and trauma
https://www.readbyqxmd.com/read/28918905/raising-suspicion-of-mistreatment-from-burns-derivation-and-validation-of-the-burn-tool
#10
Alison M Kemp, Linda Hollén, Alan M Emond, Diane Nuttall, David Rea, Sabine Maguire
BACKGROUND: 10-25% of childhood burns arise from mistreatment. AIM: To derive and validate a clinical prediction tool to assist the recognition of suspected maltreatment. METHODS: Prospectively collected data from 1327 children with burns were analyzed using logistic regression. Regression coefficients for variables associated with 'referral for child maltreatment investigation' (112 cases) in multivariable analyses were converted to integers to derive the BuRN-Tool, scoring each child on a continuous scale...
September 14, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28918904/comparison-of-laser-doppler-imaging-ldi-and-clinical-assessment-in-differentiating-between-superficial-and-deep-partial-thickness-burn-wounds
#11
Saadia Nosheen Jan, Farid Ahmed Khan, Muhammad Mustehsan Bashir, Muneeb Nasir, Hamid Hussain Ansari, Hussan Birkhez Shami, Umer Nazir, Asif Hanif, Muhammad Sohail
PURPOSE OF PRESENTATION/STUDY: To compare the accuracy of Laser Doppler Imaging (LDI) and clinical assessment in differentiating between superficial and deep partial thickness burns to decide whether early tangential excision and grafting or conservative management should be employed to optimize burn and patient management. STUDY PERIOD: March 2015 to November 2016. METHODS/PROCEDURE DETAILS: Ninety two wounds in 34 patients reporting within 5days of less than 40% burn surface area were included...
September 14, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28918733/cupping-the-risk-of-burns
#12
Marc A Seifman, K Skaria Alexander, Cheng H Lo, Heather Cleland
No abstract text is available yet for this article.
June 19, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28917473/recognizing-and-overcoming-phototherapy-induced-initiation-burn
#13
Caleb Jeon, Mio Nakamura
No abstract text is available yet for this article.
October 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28917377/the-effect-of-a-beeswax-olive-oil-and-alkanna-tinctoria-l-tausch-mixture-on-burn-injuries-an-experimental-study-with-a-control-group
#14
Kenan Gümüş, Zeynep Karaman Özlü
OBJECTIVES: This study was planned to investigate the effect of a mixture of beeswax, olive oil and A. Tinctoria (L.) Tausch on burn wounds to determine the impact on burn healing, pain during dressing changes and duration of hospital stay. METHODS: The study was conducted between May 2014 and August 2015 in the Burn Unit of Ataturk University Research Hospital. The sample of this experimental study consisted of 64 patients (31 experimental group and 33 control group) who met its inclusion criteria...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28917362/a-comparative-study-of-the-antacid-effect-of-some-commonly-consumed-foods-for-hyperacidity-in-an-artificial-stomach-model
#15
Vandana Panda, Priyanka Shinde, Jyoti Deora, Pankaj Gupta
OBJECTIVES: The incorporation of certain alkalinizing vegetables, fruits, milk and its products in the diet has been known to alleviate hyperacidity. These foods help to restore the natural gastric balance and function, curb acid reflux, aid digestion, reduce the burning sensation due to hyperacidity and soothe the inflamed mucosa of the stomach. The present study evaluates and compares the antacid effect of broccoli, kale, radish, cucumber, lemon juice, cold milk and curd in an artificial stomach model...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28917166/omi-satellite-observed-formaldehyde-column-from-2006-to-2015-over-xishuangbanna-southwest-china-and-validation-using-ground-based-zenith-sky-doas
#16
Rui Liu, Tao Feng, Shanshan Wang, Chanzhen Shi, Yanlin Guo, Jialiang Nan, Yun Deng, Bin Zhou
Formaldehyde (HCHO) provides a proxy to reveal the isoprene and biogenic volatile organic compounds emission which plays important roles in atmospheric chemical process and climate change. The ground-based observation with zenith-sky DOAS is carried out in order to validate the HCHO columns from OMI. It has a good correlation of 0.71678 between the HCHO columns from two sources. Then we use the OMI HCHO columns from January 2006 to December 2015 to indicate the interannual variation and spatial distribution in Xishuangbanna...
September 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28916849/1000-consecutive-cases-of-laser-assisted-liposuction-utilizing-the-1440%C3%A2-nm-wavelength-nd-yag-laser-assessing-the-safety-and-efficacy
#17
Christopher T Chia, Mark G Albert, Sharon Del Vecchio, Spero J Theodorou
BACKGROUND: Liposuction remains one of the most popular aesthetic surgery procedures performed today, and it has undergone continuous refinements over the past four decades. Advancements in anesthesia, improvements in instrumentation, better understanding of fluid dynamics and the addition of energy to liposuction have led to better outcomes with improved safety and efficacy. OBJECTIVES: The purpose of this study is to review 1000 consecutive laser-assisted liposuction (LAL) cases utilizing the 1440 nm wavelength...
September 15, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28916400/assessing-changes-in-the-activity-levels-of-breast-cancer-patients-during-radiation-therapy
#18
Colin E Champ, Nitin Ohri, Rainer J Klement, Matthew Cantor, Sushil Beriwal, Scott M Glaser, Ryan P Smith
BACKGROUND: Radiation therapy (RT) is often delivered after lumpectomy for women with breast cancer. A common perceived side effect of RT is fatigue, yet its exact effect on activity levels and sleep is unknown. In this study we analyzed the change in activity levels and sleep using an activity tracking device before, during, and after RT for women with early stage breast cancer and ductal carcinoma in situ who underwent adjuvant RT. PATIENTS AND METHODS: After institutional review board approval, activity levels were quantified before, during, and after RT with measurements of steps, miles walked, calories burned, and sleep metrics in 10 women fitted with activity trackers...
August 24, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28916026/a-diagnostic-and-therapeutic-approach-to-primary-burning-mouth-syndrome
#19
Siamak Moghadam-Kia, Nasim Fazel
Primary burning mouth syndrome (BMS) is an oral mucosal disorder that is characterized by a chronic and often debilitating intraoral burning sensation for which no localized or systemic cause can be found. BMS most commonly affects postmenopausal women. The pathophysiology of primary BMS is not well understood. Diagnosing BMS can prove to be challenging. BMS patients can also pose a therapeutic challenge to clinicians who are consulted to evaluate these patients. Most commonly used therapies include tricyclic antidepressants, α-lipoic acid, clonazepam, and cognitive-behavioral therapy...
September 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28915546/emergent-contaminants-endocrine-disruptors-and-their-laccase-assisted-degradation-a-review
#20
REVIEW
Carlos Barrios-Estrada, Magdalena de Jesús Rostro-Alanis, Blanca Delia Muñoz-Gutiérrez, Hafiz M N Iqbal, Soundarapandian Kannan, Roberto Parra-Saldívar
Herein, an effort has been made to highlight the trends of the state-of-the-art of laccase-assisted degradation of emerging contaminants at large and endocrine disruptors in particular. Since first described in the 19th century, laccase has received particular interest for inter- and multidisciplinary investigations due to its uniqueness and remarkable biotechnological applicability. There has always been a paramount concern over the widespread occurrences of various pollutant types, around the globe. Therefore, pollution free processes are gaining ground all over the world...
September 11, 2017: Science of the Total Environment
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