keyword
MENU ▼
Read by QxMD icon Read
search

Rhinitis and asthma

keyword
https://www.readbyqxmd.com/read/28820911/phosphatidlyinositol-3-kinase-c2-beta-pi3kc2%C3%AE-is-a-potential-new-target-to-treat-ige-mediated-disease
#1
Shekhar Srivastava, Zhai Li, Edward Y Skolnik
Cross linking of the IgE receptor (FcεRI) on mast cells plays a critical role in IgE-dependent allergy including allergic rhinitis, asthma, anaphylaxis, and delayed type hypersensitivity reactions. The Ca2+ activated K+ channel, KCa3.1, plays a critical role in IgE-stimulated Ca2+ entry and degranulation in mast cells by helping to maintain a negative membrane potential, which provides an electrochemical gradient to drive Ca2+ influx. Of the 3 classes of PI3K, the class II PI3Ks are the least studied and little is known about the roles for class II PI3Ks in vivo in the context of the whole organism under normal and pathological conditions...
2017: PloS One
https://www.readbyqxmd.com/read/28814959/poor-sleep-is-highly-associated-with-house-dust-mite-allergic-rhinitis-in-adults-and-children
#2
Damien Leger, Bénédicte Bonnefoy, Bernard Pigearias, Bertrand de La Giclais, Antoine Chartier
BACKGROUND: Sleep disorders are often underreported to physicians by patients with allergies. This study aimed to characterize the sleep disorders associated with respiratory allergy to house dust mites (HDM) at the time of initiation of sublingual allergen immunotherapy (SLIT) in routine clinical practice. METHODS: This prospective, cross-sectional, observational study was conducted between November 2014 and March 2015 at 189 French trial sites and included 1750 participants suffering from HDM allergy who were initiating SLIT...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28814359/the-risk-of-autoimmune-connective-tissue-diseases-in-patients-with-atopy-a-nationwide-population-based-cohort-study
#3
Yi-Chun Hou, Hsiao-Yun Hu, I-Lin Liu, Yun-Ting Chang, Chen-Yi Wu
BACKGROUND: The relationship between autoimmune connective tissue disease (ACTD) and atopy is controversial. OBJECTIVES: To investigate the risks of ACTDs in patients with atopic triad diseases, including atopic dermatitis, allergic rhinitis, and asthma, by using a nationwide data base. METHODS: A cohort of 155,311 patients newly diagnosed with atopic dermatitis, allergic rhinitis, or asthma in 2002-2011 was obtained from the Taiwan National Health Insurance Research Database...
September 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28814357/association-of-aeroallergen-sensitization-and-atopic-disease-in-the-sonoran-desert
#4
Ryan D Buckley, Tara F Carr
BACKGROUND: Numerous aeroallergens have been associated with the development of asthma, including Alternaria, house-dust mite, and pet dander. Tucson, Arizona, is located in the Sonoran Desert, which has the highest diversity of vegetation of any desert in the world. Given the unique pollen profile in this region, we sought to identify the most common aeroallergens associated with rhinitis and asthma diagnosis in the local adult population. OBJECTIVE: To identify the prevalence of aeroallergen sensitivity in the Tucson adult population and to identify which aeroallergens are associated with a diagnosis of asthma...
September 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28812277/milonine-an-alkaloid-of-cissampelos-sympodialis-eichl-menispermaceae-inhibits-histamine-release-of-activated-mast-cells
#5
Adriano Francisco Alves, Giciane Carvalho Vieira, Francisco Allysson A F Gadelha, Luiz Henrique Agra Cavalcante-Silva, Marco Aurélio Martins, José Maria Barbosa-Filho, Marcia Regina Piuvezam
Milonine is an alkaloid of Cissampelos sympodialis Eichl. (Menispermaceae), a plant used in the northeast of Brazil to treat allergies such as asthma, rhinitis, and other conditions. Previously, several alkaloids were isolated from its roots and leaves with pharmacological properties in asthma and acute inflammation models. Therefore, the aim of this study was to evaluate the milonine effect on mast cells degranulation in vivo and in vitro. Swiss mice (n = 8) were used in models of paw edema induced by carrageenan, compound 48/80, or histamine...
August 15, 2017: Inflammation
https://www.readbyqxmd.com/read/28811862/allergic-profiles-of-mothers-and-fathers-in-the-japan-environment-and-children-s-study-jecs-a-nationwide-birth-cohort-study
#6
Kiwako Yamamoto-Hanada, Limin Yang, Kazue Ishitsuka, Tadayuki Ayabe, Hidetoshi Mezawa, Mizuho Konishi, Testsuo Shoda, Kenji Matsumoto, Hirohisa Saito, Yukihiro Ohya
BACKGROUND: The Japan Environment and Children's Study (JECS) is a nationwide, multicenter, prospective birth cohort investigation launched by the Ministry of Environment in Japan. The purpose of the JECS is to evaluate the influence of prenatal and postnatal exposures to environmental factors on the postnatal health of the children. In this study, we evaluated the allergic characteristics of parents within the JECS cohort. METHODS: This study covered a wide geographical area and encompassed 15 regional centers...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28809842/noninvasive-sampling-of-mucosal-lining-fluid-for-the-quantification-of-in-vivo-upper-airway-immune-mediator-levels
#7
Helene M Wolsk, Bo L Chawes, Jonathan Thorsen, Jakob Stokholm, Klaus Bønnelykke, Susanne Brix, Hans Bisgaard
This protocol describes noninvasive sampling of undisturbed upper airway mucosal lining fluid. It also details the extraction procedure used prior to the analysis of immune mediators in fluid eluates for the study of the airway topical immune signature, without the need for stimulation procedures (often used by other techniques). The mucosal lining fluid is sampled on a strip of filter paper placed at the anterior part of the inferior turbinate and left for 2 min of absorption. Analytes are eluted from the filter papers, and the extracted protein-based eluates are analyzed by an electrochemiluminescence-based immunoassay, allowing for the high-sensitivity quantification of low- and high-level analytes in the same sample...
August 7, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28804700/abridged-version-of-the-awmf-guideline-for-the-medical-clinical-diagnostics-of-indoor-mould-exposure-s2k-guideline-of-the-german-society-of-hygiene-environmental-medicine-and-preventive-medicine-ghup-in-collaboration-with-the-german-association-of-allergists
#8
Gerhard A Wiesmüller, Birger Heinzow, Ute Aurbach, Karl-Christian Bergmann, Albrecht Bufe, Walter Buzina, Oliver A Cornely, Steffen Engelhart, Guido Fischer, Thomas Gabrio, Werner Heinz, Caroline E W Herr, Jörg Kleine-Tebbe, Ludger Klimek, Martin Köberle, Herbert Lichtnecker, Thomas Lob-Corzilius, Rolf Merget, Norbert Mülleneisen, Dennis Nowak, Uta Rabe, Monika Raulf, Hans Peter Seidl, Jens-Oliver Steiß, Regine Szewszyk, Peter Thomas, Kerttu Valtanen, Julia Hurraß
This article is an abridged version of the AWMF mould guideline "Medical clinical diagnostics of indoor mould exposure" presented in April 2016 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with the above-mentioned scientific medical societies, German and Austrian societies, medical associations and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established...
2017: Allergo Journal International
https://www.readbyqxmd.com/read/28803150/residential-greenness-and-allergic-respiratory-diseases-in-children-and-adolescents-a-systematic-review-and-meta-analysis
#9
REVIEW
K A Lambert, G Bowatte, R Tham, C Lodge, L Prendergast, J Heinrich, M J Abramson, S C Dharmage, B Erbas
BACKGROUND: The aetiology of allergic respiratory disease in children is not yet fully understood. Environmental factors are believed to play a major part. The amount of green vegetation surrounding the home (residential greenness) has been recently identified as a potentially important exposure OBJECTIVES: Our goal was to provide a systematic review and quantitative summary of the evidence regarding the relationship between residential greenness and allergic respiratory diseases in children...
August 10, 2017: Environmental Research
https://www.readbyqxmd.com/read/28797732/more-than-a-decade-follow-up-in-severe-or-difficult-to-treat-asthma-tenor-ii
#10
Bradley E Chipps, Tmirah Haselkorn, Brandee Paknis, Benjamin Ortiz, Eugene R Bleecker, Farid Kianifard, Aimee J Foreman, Stanley J Szefler, Robert S Zeiger
BACKGROUND: The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR I) study demonstrated high morbidity in patients with severe/difficult-to-treat asthma, despite standard-of-care treatment. OBJECTIVE: To determine the long-term natural history of disease and outcomes in patients in TENOR I, after more than a decade. METHODS: TENOR I was a multicenter, observational study (2001-2004) of 4756 patients with severe/difficult-to-treat asthma...
August 7, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28795430/occupational-contact-urticaria-and-protein-contact-dermatitis-causes-and-concomitant-airway-diseases
#11
Eva Helaskoski, Hille Suojalehto, Outi Kuuliala, Kristiina Aalto-Korte
BACKGROUND: Contact urticaria (CU) and protein contact dermatitis (PCD) are mainly induced by an immediate, IgE-mediated immunological mechanism. Immediate sensitization is also linked to asthma and/or allergic rhinitis. OBJECTIVES: To report causes of work-induced CU and PCD, and to evaluate the occurrence of concomitant airway diseases. METHODS: We retrospectively reviewed the patient files of cases diagnosed with CU or PCD at the Finnish Institute of Occupational Health during 1995-2011...
August 10, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28792151/physical-activity-sedentary-habits-sleep-and-obesity-are-associated-with-asthma-allergic-rhinitis-and-atopic-dermatitis-in-korean-adolescents
#12
Man Sup Lim, Chang Hee Lee, Songyong Sim, Sung Kwang Hong, Hyo Geun Choi
PURPOSE: Since pathophysiologic evidence has been raised to suggest that obesity could facilitate an allergic reaction, obesity has been known as an independent risk factor for allergic disease such as asthma. However, the relationship between sedentary behavior and lifestyle which could lead to obesity, and those allergic diseases remains unclear. MATERIALS AND METHODS: We analyzed the relations between physical activity, including sitting time for study, sitting time for leisure and sleep time, and obesity, asthma, allergic rhinitis, and atopic dermatitis using the Korea Youth Risk Behavior Web-based Survey, which was conducted in 2013...
September 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28775219/assessment-of-dietary-food-and-nutrient-intake-and-bone-density-in-children-with-eczema
#13
T F Leung, S S Wang, F Y Kwok, L W Leung, C M Chow, E K Hon
INTRODUCTION: Dietary restrictions are common among patients with eczema, and such practice may lead to diminished bone mineral density. This study investigated dietary intake and bone mineral density in Hong Kong Chinese children with eczema. METHODS: This cross-sectional and observational study was conducted in a university-affiliated teaching hospital in Hong Kong. Chinese children aged below 18 years with physician-diagnosed eczema were recruited from our paediatric allergy and dermatology clinics over a 6-month period in 2012...
August 4, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28768771/activation-of-mas-related-g-protein-coupled-receptors-by-the-house-dust-mite-cysteine-protease-der-p1-provides-a-new-mechanism-linking-allergy-and-inflammation
#14
Vemuri B Reddy, Ethan A Lerner
Cysteine and serine proteases function via protease-activated (PARs) and mas-related G-protein coupled receptors (Mrgprs) to contribute to allergy and inflammation. Der p1 is a cysteine protease and major allergen from the house dust mite and is associated with allergic rhinitis and allergic asthma. Der p1 activates PAR2 and induces the release of the pro-inflammatory cytokine IL-6 from cells. However, the possibility that Der p1 acts on Mrgprs has not been considered. We report here that ratiometric calcium imaging reveals that Der p1 activates the human receptor MRGPRX1 and the mouse homolog MrgprC11, implicated previously in itch...
August 2, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28765818/characteristics-of-airborne-pollen-in-incheon-and-seoul-2015-2016
#15
Hye Ju So, Soon Jeong Moon, Seon Yeong Hwang, Jeong Hee Kim, Hae Ji Jang, Jung Heum Jo, Tae Jung Sung, Dae Hyun Lim
BACKGROUND: Pollen allergens are one of the main contributors to the development and/or aggravation of allergic rhinitis, allergic conjunctivitis, and asthma. OBJECTIVE: An examination of the airborne pollen in residential areas should be conducted to aid the diagnosis and treatment of allergic diseases. METHODS: Airborne pollen samples were collected from 2 sites in Incheon and 2 in Seoul from 2015 to 2016. RESULTS: The highest monthly concentration of airborne pollen was observed in May and September each year...
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28763131/the-effect-of-allergen-induced-bronchoconstriction-on-concentration-of-5-oxo-ete-in-exhaled-breath-condensate-of-house-dust-mite-allergic-patients
#16
Krzysztof Kowal, Anna Gielicz, Marek Sanak
BACKGROUND: Arachidonic acid metabolites regulate several aspects of airway function including inflammation, muscle contraction and mucous secretion. OBJECTIVE: The aim of this study was to evaluate concentration of selected 5-lipoxygenase (LOX) and cyclooxygenase (COX)-derived eicosanoids in exhaled breath condensate (EBC) during allergen induced bronchoconstriction. METHODS: The study was performed on 24 allergic rhinitis/asthma patients sensitized to a house dust mite (HDM) Dermatophagoides pteronyssinus (Dp) and 13 healthy controls (HCs)...
August 1, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28762062/sequential-rituximab-and-omalizumab-for-the-treatment-of-eosinophilic-granulomatosis-with-polyangiitis-churg-strauss-syndrome
#17
REVIEW
David Aguirre-Valencia, Iván Posso-Osorio, Juan-Carlos Bravo, Fabio Bonilla-Abadía, Gabriel J Tobón, Carlos A Cañas
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome (CSS), is a small vessel vasculitis associated with eosinophilia and asthma. Clinical manifestations commonly seen in patients presenting with EGPA range from upper airway and lung involvement to neurological, cardiac, cutaneous, and renal manifestations. Treatment for severe presentations includes steroids, cyclophosphamide, plasmapheresis, and recently, rituximab. Rituximab is associated with a good response in the treatment of vasculitis, but a variable response for the control of allergic symptoms...
July 31, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28755730/is-decreased-mean-platelet-volume-in-allergic-airway-diseases-associated-with-extent-of-the-inflammation-area
#18
Recep Akgedik, Yasin Yağız
OBJECTIVE: The aim of this study was to determine the relationship between mean platelet volume (MPV) level and the extent of airway inflammation in allergic airway diseases and in subgroups by comparison of inflammatory markers. MATERIALS AND METHODS: A retrospective examination was made of 250 patients with allergic airway disease in the symptomatic phase, who had been newly diagnosed or who had abandoned treatment for at least 6 months. These patients were separated into 3 groups of asthma without allergic rhinitis (A - AR, n = 107), asthma with allergic rhinitis (A + AR, n = 83) and allergic rhinitis without asthma (AR - A, n = 60)...
July 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28750923/didox-3-4-dihydroxybenzohydroxamic-acid-suppresses-il-33-induced-cytokine-production-in-primary-mouse-mast-cells
#19
Heather L Caslin, Jamie Josephine Avila McLeod, Andrew J Spence, Amina Abdul Qayum, Elizabeth Motunrayo Kolawole, Marcela T Taruselli, Anuya Paranjape, Howard L Elford, John J Ryan
While IgE is considered the primary mediator of mast cell activation, IL-33 contributes substantially in asthma, allergic rhinitis, and atopic dermatitis. To develop effective treatments for allergic disease, it is important to understand the role of therapeutic agents on IL-33 activation. We examined the effect of Didox (3,4-dihydroxybenzohydroxamic acid), an antioxidant and ribonucleotide reductase (RNR) inhibitor, on IL-33-mediated mast cell activation. Didox suppressed IL-6, IL-13, TNF, and MIP-1α (CCL3) production in bone marrow derived mast cells following IL-33 activation...
July 11, 2017: Cellular Immunology
https://www.readbyqxmd.com/read/28749014/use-of-the-control-of-allergic-rhinitis-and-asthma-test-and-pulmonary-function-tests-to-assess-asthma-control-in-pregnancy
#20
Luís Amaral, Carla Martins, Alice Coimbra
INTRODUCTION: Asthma is one of the most prevalent chronic medical conditions to complicate pregnancy. Similarly, active management strategies that prioritise asthma control in this vulnerable population can have a far-reaching impact. AIM: To describe lung function parameters and results of the Control of Allergic Rhinitis and Asthma Test (CARAT) questionnaire in pregnant asthmatics and to analyse correlations between lung function tests and CARAT results. METHODS: All pregnant asthmatics who performed spirometry and CARAT between September 2014 and August 2015 were included...
July 27, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
keyword
keyword
19776
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"