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https://www.readbyqxmd.com/read/28441573/the-role-of-negative-affect-and-message-credibility-in-perceived-effectiveness-of-smokeless-tobacco-health-warning-labels-in-navi-mumbai-india-and-dhaka-bangladesh-a-moderated-mediation-analysis
#1
Seema Mutti-Packer, Jessica L Reid, James F Thrasher, Daniel Romer, Geoffrey T Fong, Prakash C Gupta, Mangesh S Pednekar, Nigar Nargis, David Hammond
OBJECTIVE: There is strong evidence showing that pictorial health warnings are more effective than text-only warnings. However, much of this evidence comes from high-income countries and is limited to cigarette packaging. Moreover, few studies have identified mechanisms that might explain the impact of warnings. METHODS: The current study examined the potential mediating role of negative affect and the moderating influence of message credibility in perceived effectiveness of smokeless tobacco warnings in two low- and middle-income countries (LMICs)...
April 4, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28420921/potential-of-ascorbic-acid-as-antioxidant-on-chemotherapeutic-agent-induced-change-in-morphology-of-testes
#2
Aisha Abdul Haq, Soofia Nigar, Dureshewar Rehman
OBJECTIVE: To demonstrate the morphological changes in number of seminiferous tubules that are produced by anthracycline doxorubicin on the testes of mice. METHODS: This experimental study was conducted at Dow University of Health Sciences, Karachi, from March to August 2012, and comprised male mice aged up to five weeks. The mice were separated into 3 equal groups: A, B and C. Each animal was treated with normal saline 1ml intraperitoneal in group A, doxorubicin alone in group B and doxorubicin + vitamin C in group C...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28265170/reliability-and-validity-of-the-turkish-version-of-the-fibromyalgia-rapid-screening-tool-first
#3
Reyhan Celiker, Lale Altan, Aylin Rezvani, Ilknur Aktas, Nurettin Tastekin, Erbil Dursun, Nigar Dursun, Selda Sarıkaya, Senay Ozdolap, Kenan Akgun, Coskun Zateri, Murat Birtane
[Purpose] An easy-to-use, psychometrically validated screening tool for fibromyalgia is needed. This study aims to evaluate the reliability and validity of the Turkish version of the Fibromyalgia Rapid Screening Tool by correlating it with 2013 American College of Rheumatology alternative diagnostic criteria and the Hospital Anxiety and Depression Scale. [Subjects and Methods] Subjects were 269 Physical Medicine and Rehabilitation clinic outpatients. Patients completed a questionnaire including the Fibromyalgia Rapid Screening Tool (twice), 2013 American College of Rheumatology alternative diagnostic criteria, and the Hospital Anxiety and Depression Scale...
February 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28258562/the-relationship-between-migraine-headache-and-asthma-features
#4
Nigar Dirican, Seden Demirci, Munire Cakir
Migraine and asthma are comorbid chronic disorders with episodic attacks thought to involve inflammatory and neurological mechanisms. The objective of the present study is to investigate the relationship of asthma features between the asthma patients with migraine and those without migraine headache. A cross-sectional study was conducted from October 2015 to June 2016. Physician-diagnosed asthma patients aged 18 years and above were included. Demographic data, pulmonary function test and treatment of asthma were recorded...
March 3, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28248961/effects-of-different-phosphate-lowering-strategies-in-patients-with-ckd-on-laboratory-outcomes-a-systematic-review-and-nma
#5
Nigar Sekercioglu, Argie Angeliki Veroniki, Lehana Thabane, Jason W Busse, Noori Akhtar-Danesh, Alfonso Iorio, Luciane Cruz Lopes, Gordon H Guyatt
BACKGROUND: Chronic kidney disease-mineral and bone disorder (CKD-MBD), a complication of chronic kidney disease, has been linked to reduced quality and length of life. High serum phosphate levels that result from CKD-MBD require phosphate-lowering agents, also known as phosphate binders. The objective of this systematic review is to compare the effects of available phosphate binders on laboratory outcomes in patients with CKD-MBD. METHODS: Data sources included MEDLINE and EMBASE from January 1996 to April 2016, and the Cochrane Register of Controlled Trials up to April 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28235460/tyrozine-d-oxidation-and-redox-equilibrium-in-photosystem-ii
#6
Nigar Ahmadova, Felix M Ho, Stenbjörn Styring, Fikret Mamedov
Tyrosine D (TyrD) is an auxiliary redox active tyrosine residue in photosystem II (PSII). The mechanism of TyrD oxidation was investigated by EPR spectroscopy, flash-induced fluorescence decay and thermoluminescence measurements in PSII enriched membranes from spinach. PSII membranes were chemically treated with 3mM ascorbate and 1mM diaminodurene and subsequent washing, leading to the complete reduction of TyrD. TyrD oxidation kinetics and competing recombination reactions were measured after a single saturating flash in the absence and presence of DCMU (inhibitor of the QB-site) in the pH range of 4...
February 21, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28179699/referral-pattern-of-emergencies-in-obstetrics-implications-for-defining-scope-of-services-and-policy
#7
Rahat Najam Qureshi, Rozina Sikandar, Zahra Hoodbhoy, Raffat Bano, Nigar Jabeen
OBJECTIVE: To analyse referral pattern of high-risk obstetric cases from secondary to tertiary care hospitals and to assess their maternal and neonatal outcomes. METHODS: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised all referred obstetric cases from secondary-level hospitals to tertiary-level care within and outside the Hospital between January 2011 and December 2014. Day and time of referral, reason for referral as well as maternal and neonatal outcomes were collected...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138063/global-economic-cost-of-smoking-attributable-diseases
#8
Mark Goodchild, Nigar Nargis, Edouard Tursan d'Espaignet
BACKGROUND: The detrimental impact of smoking on health has been widely documented since the 1960s. Numerous studies have also quantified the economic cost that smoking imposes on society. However, these studies have mostly been in high income countries, with limited documentation from developing countries. The aim of this paper is to measure the economic cost of smoking-attributable diseases in countries throughout the world, including in low- and middle-income settings. METHODS: The Cost of Illness approach is used to estimate the economic cost of smoking attributable-diseases in 2012...
January 30, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28134984/conversion-from-sirolimus-to-everolimus-in-long-term-liver-graft-recipients
#9
Nina Weiler, Nigar Bilge, Sven Troetschler, Johannes Vermehren, Andreas Anton Schnitzbauer, Eva Herrmann, Christoph Sarrazin, Stefan Zeuzem, Martin-Walter Welker
Immunosuppression by inhibition of the mechanistic target of rapamycin (mTOR) is a promising approach after liver transplantation. The mTOR inhibitor sirolimus was used in selected liver graft recipients despite safety concerns and lack of approval. Everolimus is another mTOR inhibitor approved after liver transplantation. It is currently unknown, whether conversion of sirolimus to everolimus is safe in long-term liver graft recipients. Long-term liver graft recipients treated with sirolimus were converted to everolimus...
January 30, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28055018/sumoylation-deficient-prdx6-gains-protective-function-by-amplifying-enzymatic-activity-and-stability-and-escapes-oxidative-stress-induced-aberrant-sumoylation
#10
Bhavana Chhunchha, Eri Kubo, Nigar Fatma, Dhirendra P Singh
Aberrant Sumoylation of protein(s) in response to oxidative stress or during aging is known to be involved in etiopathogenesis of many diseases. Upon oxidative stress, Peroxiredoxin (Prdx) 6 is aberrantly Sumoylated by Sumo1, resulting in loss of functions and cell death. We identified lysines (K) 122 and 142 as the major Sumo1 conjugation sites in Prdx6. Intriguingly, the mutant Prdx6 K122/142 R (arginine) gained protective efficacy, increasing in abundance and promoting glutathione (GSH) peroxidase and acidic calcium-independent phospholipase A2 (aiPLA2) activities...
January 5, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28026849/prevalence-and-distribution-of-fabella-a-radiographic-study-in-turkish-subjects
#11
Omer Faruk Egerci, Ozkan Kose, Adil Turan, Omer Faruk Kilicaslan, Rahime Sekerci, Nigar Keles-Celik
BACKGROUND: The purpose of this study is to examine the plain knee radiographs in Turkish subjects in order to determine the prevalence of fabella and analyze the differences between age, gender, laterality and its symmetry pattern. MATERIALS AND METHODS: Bilateral antero-posterior and lateral knee radiographs of 500 patients (250 male and 250 female subjects, 1000 knee radiographs) were randomly selected from the clinical database and retrospectively evaluated...
December 27, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27995729/is-serum-level-of-nestin-useful-in-detecting-epithelial-ovarian-cancer
#12
Veysel Sal, Ilker Kahramanoglu, Tugan Bese, Fuat Demirkiran, Nigar Sofiyeva, Zeynep Soyman, Sinem Durmus, Remisa Gelisgen, Macit Arvas, Hafize Uzun
AIM: The aim of the present study was to evaluate the usefulness of nestin as a discriminative marker between benign and malignant ovarian tumors. METHODS: During the 1 year from January 2015 through December 2015, a nonconsecutive series of 80 patients (40 malignant, 40 benign) who underwent surgery for an adnexal mass were enrolled in the study. Intraoperative frozen section evaluation was performed if there was a suspicion in diagnosis. Statistical analyses were performed using spss ver...
December 19, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27969066/depression-among-indian-university-students-and-its-association-with-perceived-university-academic-environment-living-arrangements-and-personal-issues
#13
Sibnath Deb, Parveen R Banu, Shinto Thomas, R Vishnu Vardhan, P Tirupathi Rao, Nigar Khawaja
The aim of the study is to ascertain the level of depression among university students across gender, academic stream, semesters, perception of family environment and relationship with parents, academic performance, and family income. In addition, the study examines the association between students' perceived university academic environment, living arrangements, personal issues, and depression. Seven hypotheses were formulated for verification. A total of 717 students were recruited following the multistage cluster sampling method, and data were collected by a specially designed structured questionnaire, academic achievement record and a standardized University Students Depression Inventory...
October 2016: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/27900560/serum-leptin-obestatin-and-ghrelin-levels-and-gastric-emptying-rates-of-liquid-and-solid-meals-in-non-obese-rats-with-roux-en-y-bypass-surgery-or-prosthesis-placement-implications-for-the-role-of-vagal-afferents
#14
Yunus Yavuz, Zarife Nigar Özdemir Kumral, Gülsün Memi, Özge Dağdeviren Çevik, Cumhur Yeğen, Berrak Ç Yeğen
BACKGROUND: The present study aimed to investigate the effects of Roux-en-Y gastric bypass (RYGB) and prosthesis placement on gastric emptying rate in conjunction with serum ghrelin-obestatin-leptin responses in non-obese rats with intact or denervated afferent innervation. METHODS: Under anesthesia, male Sprague-Dawley rats underwent either sham operation, RYGB, prosthesis, and/or Gregory cannula placement. Three weeks later, liquid or solid gastric emptying tests were performed and serum ghrelin, leptin and obestatin levels were measured...
November 29, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27897441/effects-of-molsidomine-on-retinopathy-and-oxidative-stress-induced-by-radiotheraphy-in-rat-eyes
#15
Murat Atabey Özer, Nihat Polat, Serkan Özen, Hakan Parlakpınar, Kemal Ekici, Alaaddin Polat, Nigar Vardı, Kevser Tanbek, Azibe Yildiz
PURPOSE: To determine the role of Molsidomine in preventing radiation-induced retinopathy after head and neck region irradiation of rats with a single radiation dose of 15 Gy. MATERIALS AND METHODS: Male Wistar albino rats were randomly grouped into five as follows: (1) control group rats, which were applied through an intraperitoneal (i.p.) vehicle without radiotherapy (RT); (2) RT group rats received a single dose of 15 Gy irradiation and after daily 0.1 ml vehicle i...
November 29, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27890978/patterns-of-use-and-perceptions-of-harm-of-smokeless-tobacco-in-navi-mumbai-india-and-dhaka-bangladesh
#16
Seema Mutti, Jessica L Reid, Prakash C Gupta, Mangesh S Pednekar, Gauri Dhumal, Nigar Nargis, Akm Ghulam Hussain, David Hammond
BACKGROUND: Globally, smokeless tobacco use is disproportionately concentrated in low-income and middle-income countries like India and Bangladesh. OBJECTIVES: The current study examined comparative patterns of use and perceptions of harm for different smokeless tobacco products among adults and youth in Navi Mumbai, India, and Dhaka, Bangladesh. METHODS: Face-to-face interviews were conducted on tablets with adult (19 years and older) smokeless tobacco users and youth (16-18 years) users and non-users in Navi Mumbai (n = 1002), and Dhaka (n = 1081)...
October 2016: Indian Journal of Community Medicine
https://www.readbyqxmd.com/read/27882101/effects-of-dexpanthenol-on-acetic-acid-induced-colitis-in-rats
#17
Yasir Furkan Cagin, Hakan Parlakpinar, Nigar Vardi, Alaadin Polat, Yahya Atayan, Mehmet Ali Erdogan, Kevser Tanbek
While the pathogenesis of acetic acid (AA)-induced colitis is unclear, reactive oxygen species are considered to have a significant effect. The aim of the present study was to elucidate the therapeutic potential of dexpanthenol (Dxp) on the amelioration of colitis in rats. Group I (n=8; control group) was intrarectally administered 1 ml saline solution (0.9%); group II [n=8; AA] was administered 4% AA into the colon via the rectum as a single dose for three consecutive days; group III (n=8; AA + Dxp) was administered AA at the same dosage as group II from day 4, and a single dose of Dxp was administered intraperitoneally; and group IV (n=8; Dxp) was administered Dxp similarly to Group III...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27823941/the-protonation-state-around-tyrd-tyrd-%C3%A2-in-photosystem-ii-is-reflected-in-its-biphasic-oxidation-kinetics
#18
Johannes Sjöholm, Felix Ho, Nigar Ahmadova, Katharina Brinkert, Leif Hammarström, Fikret Mamedov, Stenbjörn Styring
The tyrosine residue D2-Tyr160 (TyrD) in photosystem II (PSII) can be oxidized through charge equilibrium with the oxygen evolving complex in PSII. The kinetics of the electron transfer from TyrD has been followed using time-resolved EPR spectroscopy after triggering the oxidation of pre-reduced TyrD by a short laser flash. After its oxidation TyrD is observed as a neutral radical (TyrD(•)) indicating that the oxidation is coupled to a deprotonation event. The redox state of TyrD was reported to be determined by the two water positions identified in the crystal structure of PSII [Saito et al...
February 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27804080/a-critical-appraisal-of-chronic-kidney-disease-mineral-and-bone-disorders-clinical-practice-guidelines-using-the-agree-ii-instrument
#19
REVIEW
Nigar Sekercioglu, Reem Al-Khalifah, Joycelyne Efua Ewusie, Rosilene M Elias, Lehana Thabane, Jason W Busse, Noori Akhtar-Danesh, Alfonso Iorio, Tetsuya Isayama, Juan Pablo Díaz Martínez, Ivan D Florez, Gordon H Guyatt
BACKGROUND: Patients with chronic kidney disease mineral and bone disorders (CKD-MBD) suffer high rates of morbidity and mortality, in particular related to bone and cardiovascular outcomes. The management of CKD-MBD remains challenging. The objective of this systematic survey is to critically appraise clinical practice guidelines (CPGs) addressing CKD-MBD. METHODS/DESIGN: Data sources included MEDLINE, EMBASE, the National Guideline Clearinghouse, Guideline International Network and Turning Research into Practice up to May 2016...
February 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/27803754/the-diagnostic-significance-of-signal-peptide-complement-c1r-c1s-uegf-and-bmp1-epidermal-growth-factor-domain-containing-protein-1-levels-in-pulmonary-embolism
#20
Nigar Dirican, Ali Duman, Gülcan Sağlam, Akif Arslan, Onder Ozturk, Sule Atalay, Ahmet Bircan, Ahmet Akkaya, Munire Cakir
BACKGROUND: Pulmonary embolism (PE) is a common and potentially life-threatening disorder. Patients with PE often have nonspecific symptoms, and the diagnosis is often delayed. AIM: The aim of our study was to investigate the role of signal peptide-complement C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein 1 (SCUBE1) used in the diagnosis of PE. METHODS: The study was designed prospectively. A total of 57 patients who were admitted to emergency service with clinically suspected PE were included in the study...
October 2016: Annals of Thoracic Medicine
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