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https://www.readbyqxmd.com/read/28742949/strategies-to-increase-the-efficacy-of-using-gut-microbiota-for-the-modulation-of-obesity
#1
REVIEW
J Li, M S Riaz Rajoka, D Shao, C Jiang, M Jin, Q Huang, H Yang, J Shi
Obesity is one of the most serious global public health challenges of the 21st century. The adjustment of gut microbiota is often recommended as an efficient strategy to treat obesity. This modulation of gut microbiota can be performed by many methods, including dietary intervention, antibiotic application, the use of prebiotics and probiotics, bariatric surgery and faecal microbiota transplantation. In most cases, positive effects have been observed in response to treatment, but invalid and even contrary effects have also been observed in some cases due to factors that are unrelated to intervention methods, such as genetic factors, patient age or gender, environmental microbiota, climate, geography and lifestyle...
July 25, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28742680/individualized-metabolic-surgery-score-procedure-selection-based-on-diabetes-severity
#2
Ali Aminian, Stacy A Brethauer, Amin Andalib, Amy S Nowacki, Amanda Jimenez, Ricard Corcelles, Zubaidah Nor Hanipah, Suriya Punchai, Deepak L Bhatt, Sangeeta R Kashyap, Bartolome Burguera, Antonio M Lacy, Josep Vidal, Philip R Schauer
OBJECTIVE: To construct and validate a scoring system for evidence-based selection of bariatric and metabolic surgery procedures according to severity of type 2 diabetes (T2DM). BACKGROUND: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) account for >95% of bariatric procedures in United States in patients with T2DM. To date, there is no validated model to guide procedure selection based on long-term glucose control in patients with T2DM. METHODS: A total of 659 patients with T2DM who underwent RYGB and SG at an academic center in the United States and had a minimum 5-year follow-up (2005-2011) were analyzed to generate the model...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28742255/weight-management-strategies-for-those-with-chronic-kidney-disease-a-consensus-report-from-the-asia-pacific-society-of-nephrology-and-australia-and-new-zealand-society-of-nephrology-2016-renal-dietitians-meeting
#3
Kelly Lambert, Jo Beer, Ruth Dumont, Katie Hewitt, Karen Manley, Anthony Meade, Karen Salamon, Katrina Campbell
AIM: Develop a consensus report to guide dietetic management of overweight or obese individuals with Chronic Kidney Disease (CKD). METHODS: Six statements relating weight management in CKD guided a comprehensive review of the literature. A summary of the evidence was then presented at the renal nutrition meeting of the 2016 Asia Pacific Society of Nephrology and Australia and New Zealand Society of Nephrology. Majority agreement was defined as group agreement on a statement of between 50-74%, and consensus was considered ≥ 75% agreement...
July 25, 2017: Nephrology
https://www.readbyqxmd.com/read/28741239/type-2-diabetes-mellitus-and-simple-glucose-metabolism-parameters-may-reliably-predict-nonalcoholic-fatty-liver-disease-features
#4
Everton Cazzo, Laísa Simakawa Jimenez, Martinho Antonio Gestic, Murillo Pimentel Utrini, Fábio Henrique Mendonça Chaim, Felipe David Mendonça Chaim, José Carlos Pareja, Elinton Adami Chaim
OBJECTIVE: This study aims to investigate the correlation between features of NAFLD among individuals with morbid obesity and the surrogate IR markers homeostasis model assessment (HOMA), product of triglycerides and glucose (TyG), and triglyceride-to-high-density-lipoprotein ratio (TG/HDL-c). METHODS: A cross-sectional study, which enrolled 89 individuals who consecutively underwent bariatric surgery from February through December 2015, was conducted. NAFLD was assessed through histological examination of liver biopsies and correlated with the values of HOMA, TyG, and TG/HDL-c and their respective cutoff points for insulin resistance (IR)...
July 24, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28740414/the-role-of-endoscopic-therapy-in-obesity-management-intragastric-balloons-and-aspiration-therapy
#5
REVIEW
Nitin Kumar, Shelby Sullivan, Christopher C Thompson
Weight management is increasingly incorporating endoscopic bariatric therapy (EBT). As the global burden of obesity and its comorbidities has increased, it is evident that novel therapeutic approaches will be necessary to address the obesity epidemic. EBTs offer greater efficacy than diet and lifestyle modification and lower invasiveness than bariatric surgery. The US Food and Drug Administration has approved two intragastric balloons and aspiration therapy for the treatment of obesity: Apollo Orbera is indicated for the treatment of Class I and Class II obesity, Re Shape Integrated Dual Balloon system is indicated for the same range with a comorbidity, and Aspire Bariatrics AspireAssist is approved for patients with a body mass index of 35-55 kg/m(2)...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/28739415/human-factors-evaluation-of-surgeons-working-positions-for-gynaecological-minimal-access-surgery
#6
Sue Hignett, Diane Gyi, Lisa Calkins, Laura Jones, Esther Moss
STUDY OBJECTIVE: To investigate work-related musculoskeletal disorders (WRMSD) in gynaecological minimal access surgery (MAS), including bariatric (plus size) patients DESIGN: Mixed methods DESIGN CLASSIFICATION: Level III (descriptive and qualitative) SETTING: UK Teaching Hospital PATIENTS: Not applicable INTERVENTIONS: Not applicable MEASUREMENTS: Survey, observations (anthropometry, postural analysis) and interviews. RESULTS: WRMSD were present in 63% of survey respondents (n=67)...
July 21, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28739098/effects-of-bariatric-surgery-on-energy-homeostasis
#7
REVIEW
Wei Li, Denis Richard
Bariatric surgery represents the most efficient therapy for severe obesity. It reduces the size of fat stores or the amount of body fat gain. The bariatric surgery procedures currently used include Roux-en-Y gastric bypass and sleeve gastrectomy, which are the most commonly performed procedures. Other procedures are laparoscopic adjustable gastric banding and biliopancreatic diversion. The latter represents the most effective surgery for treatment of severe obesity as well as type 2 diabetes. Bariatric surgery reduces energy intake by restricting the size of the stomach reservoir and causing malabsorption, as in the case of biliopancreatic diversion...
August 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28739096/a-canadian-and-historical-perspective-on-bariatric-surgery
#8
Laurent Biertho, Simon Marceau, Simon Biron
No abstract text is available yet for this article.
August 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28739095/the-rapidly-evolving-landscape-of-bariatric-surgery
#9
EDITORIAL
Andre Tchernof, S John Weisnagel
No abstract text is available yet for this article.
August 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28738340/novel-positional-devices-for-the-treatment-of-positional-obstructive-sleep-apnea-and-how-this-relates-to-sleep-surgery
#10
Madeline J L Revesloot, Linda Benoist, Peter van Maanen, Nico de Vries
If untreated, obstructive sleep apnea (OSA) develops as a gradual progressive disease. In the early stage of the disease most patients with OSA are positional. The archetypical patient might progress from simple positional snoring via positional early-stage mild disease to less positional moderate and finally nonpositional severe OSA. At first, the apnea-hypopnea index (AHI) is high only in the supine position, and later is high in all sleeping positions. The phenomenon is reversible. After partial effective treatment, patients with severe OSA can reverse to less severe positional OSA or, in other words, the AHI drops more in the lateral position than in supine position...
2017: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28737553/complications-after-body-contouring-surgery-in-postbariatric-patients
#11
Alejandra García Botero, Miguel García Wenninger, Dario Fernández Loaiza
INTRODUCTION: Over recent years, body contouring procedures in postbariatric patients have been in exponentially growing demand resulting in high complication rates rendering a variety of ciphers in the literature. OBJECTIVE: The purpose of this study is to determine the complication rate in patients who have undergone body contouring surgery after bariatric surgery between June 2012 and March 2015 at Hospital de San José. METHODS: A cohort study including 153 individuals who underwent a total of 198 body contouring procedures after massive weight loss following bariatric surgery was conducted...
July 22, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28736384/-revisional-surgery-for-nonstandard-gastric-bypass-a-case-report
#12
Yu Gao, Zhi-Gang Ke, Jian-Guo Liu, Wei-Dong Tong
Bariatric surgery is the most effective treatment for obesity with or without type 2 diabetes mellitus and its complications. With the growing incidence of type 2 diabetes mellitus, the number of hospitals performing bariatric surgery and surgical cases increase substantially. The problems in operation standardization, quality control of operation and postoperative management of the patients cause the failure in weight loss, hypoglycemia and severe complications, and revisional surgery is often required to correct the condition...
July 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28735376/the-socio-economic-impact-of-bariatric-surgery
#13
Arendse Tange Larsen, Betina Højgaard, Rikke Ibsen, Jakob Kjellberg
INTRODUCTION: A recurring argument for bariatric surgery is cost savings due to sustained weight loss and reductions in comorbidities. However, studies prompting this argument tend to focus only on health care costs, and in some of them, cost changes after surgery have been modelled. The aim of this study was to generate real-world evidence on the socio-economic impact of bariatric surgery, by evaluating the effect on both direct and indirect costs. MATERIALS AND METHODS: Using real-world data from national registries, predictions of health care costs, social transfer payments and income were performed for a surgically treated individual and compared to those for a similar but non-surgically treated individual 3 years before and after surgery...
July 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28735374/changes-in-global-transcriptional-profiling-of-women-following-obesity-surgery-bypass
#14
Marcela Augusta de Souza Pinhel, Natalia Yumi Noronha, Carolina Ferreira Nicoletti, Bruno Affonso Parente de Oliveira, Cristiana Cortes-Oliveira, Vitor Caressato Pinhanelli, Wilson Salgado Junior, Ana Julia Machry, Wilson Araújo da Silva Junior, Dorotéia Rossi Silva Souza, Júlio Sérgio Marchini, Carla Barbosa Nonino
BACKGROUND: Differential gene expression in peripheral blood mononuclear cells (PBMCs) after Roux-en-Y gastric bypass (RYGB) is poorly characterized. Markers of these processes may provide a deeper understanding of the mechanisms that underlie these events. The main goal of this study was to identify changes in PBMC gene expression in women with obesity before and 6 months after RYGB-induced weight loss. METHODS: The ribonucleic acid (RNA) of PBMCs from 13 obese women was analyzed before and 6 months after RYGB; the RNA of PBMCs from nine healthy women served as control...
July 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28734574/early-reduction-of-matrix-metalloproteinase-8-serum-levels-is-associated-with-leptin-drop-and-predicts-diabetes-remission-after-bariatric-surgery
#15
Luca Liberale, Aldo Bonaventura, Federico Carbone, Maria Bertolotto, Paola Contini, Nicola Scopinaro, Giovanni Bruno Camerini, Francesco Saverio Papadia, Renzo Cordera, Giovanni Guido Camici, Franco Dallegri, Gian Franco Adami, Fabrizio Montecucco
BACKGROUND: We aimed at investigating whether the acute abrogation of leptin after bariatric surgery is able to reduce neutrophil activation and potentially affect type 2 diabetes mellitus (T2DM) remission. METHODS: Metabolic and inflammatory parameters (i.e. leptin, IL-6 and neutrophil products) were compared at baseline (before bariatric surgery), one month, one and three years after surgery in morbid obese (MOB) T2DM patients (n=12) and non-MOB controls (n=32)...
July 13, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28734462/effect-of-bariatric-surgery-on-emergency-department-visits-and-hospitalizations-for-atrial-fibrillation
#16
Yuichi J Shimada, Yusuke Tsugawa, Carlos A Camargo, David F M Brown, Kohei Hasegawa
Atrial fibrillation (AF) and obesity are major health problems in the United States. However, little is known about whether bariatric surgery affects AF-related morbidities. This study investigated whether bariatric surgery is associated with short-term and long-term changes in the risk of emergency department (ED) visits or hospitalizations for AF. We performed a self-controlled case series study of obese adults with AF who underwent bariatric surgery by using population-based ED and inpatient databases in California, Florida, and Nebraska from 2005 to 2011...
June 27, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28733906/the-advanced-diarem-score-improves-prediction-of-diabetes-remission-1%C3%A2-year-post-roux-en-y-gastric-bypass
#17
Judith Aron-Wisnewsky, Nataliya Sokolovska, Yuejun Liu, Doron S Comaneshter, Shlomo Vinker, Tal Pecht, Christine Poitou, Jean-Michel Oppert, Jean-Luc Bouillot, Laurent Genser, Dror Dicker, Jean-Daniel Zucker, Assaf Rudich, Karine Clément
AIMS/HYPOTHESIS: Not all people with type 2 diabetes who undergo bariatric surgery achieve diabetes remission. Thus it is critical to develop methods for predicting outcomes that are applicable for clinical practice. The DiaRem score is relevant for predicting diabetes remission post-Roux-en-Y gastric bypass (RYGB), but it is not accurate for all individuals across the entire spectrum of scores. We aimed to develop an improved scoring system for predicting diabetes remission following RYGB (the Advanced-DiaRem [Ad-DiaRem])...
July 21, 2017: Diabetologia
https://www.readbyqxmd.com/read/28733905/glp-1-glucagon-receptor-co-agonism-for-treatment-of-obesity
#18
REVIEW
Miguel A Sánchez-Garrido, Sara J Brandt, Christoffer Clemmensen, Timo D Müller, Richard D DiMarchi, Matthias H Tschöp
Over a relatively short period, obesity and type 2 diabetes have come to represent a large medical and economic burden to global societies. The epidemic rise in the prevalence of obesity has metabolic consequences and is paralleled by an increased occurrence of other diseases, such as diabetes, cancer and cardiovascular complications. Together, obesity and type 2 diabetes constitute one of the more preventable causes of premature death and the identification of novel, safe and effective anti-obesity drugs is of utmost importance...
July 21, 2017: Diabetologia
https://www.readbyqxmd.com/read/28733222/molecular-classification-of-hepatocellular-adenoma-in-clinical-practice
#19
REVIEW
Jean-Charles Nault, Valérie Paradis, Daniel Cherqui, Valérie Vilgrain, Jessica Zucman-Rossi
Incidental liver lesion depicted on preoperative imaging for bariatric surgery (BMI = 42) in a 34 year-old woman with oral contraceptive use of 15 years, normal blood liver tests and high CRP (11 mg/L, Nl <6). MRI showed a 6 cm liver nodule in segment V close to the gallbladder. The nodule was moderately hyperintense on T1 (in-phase) and showed a marked and heterogeneous drop in signal intensity on opposedphase sequence suggesting the presence of fat. On T2, the nodule was heterogeneous, hyperintense at the periphery and hypointense in most of the central part...
July 18, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28731054/does-bariatric-surgery-prevent-progression-of-diabetic-retinopathy
#20
Y Chen, J P Laybourne, M T Sandinha, N Mw de Alwis, P Avery, D H Steel
PurposeTo assess the changes in diabetic retinopathy (DR) in type 2 diabetes (T2DM) patients post bariatric surgery and report on the risk factors that may be associated with it.Patients and methodsRetrospective observational study of T2DM patients who underwent bariatric surgery in a UK specialist bariatric unit between 2009 and 2015. Preoperative and postoperative weight, HbA1c, and annual DR screening results were collected from medical records. Patients with preoperative retinal screening and at least one postoperative retinal screening were eligible for analysis...
July 21, 2017: Eye
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