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Gilles deleuze

David G Cox, Elsa Curtit, Gilles Romieu, Pierre Fumoleau, Maria Rios, Hervé Bonnefoi, Thomas Bachelot, Patrick Soulié, Christelle Jouannaud, Hugues Bourgeois, Thierry Petit, Isabelle Tennevet, David Assouline, Marie-Christine Mathieu, Jean-Philippe Jacquin, Sandrine Lavau-Denes, Ariane Darut-Jouve, Jean-Marc Ferrero, Carole Tarpin, Christelle Lévy, Valérie Delecroix, Véronique Trillet-Lenoir, Oana Cojocarasu, Jérôme Meunier, Jean-Yves Pierga, Céline Faure-Mercier, Hélène Blanché, Mourad Sahbatou, Anne Boland, Delphine Bacq, Céline Besse, Jean-François Deleuze, Iris Pauporté, Gilles Thomas, Xavier Pivot
Genetic polymorphisms are associated with breast cancer risk. Clinical and epidemiological observations suggest that clinical characteristics of breast cancer, such as estrogen receptor or HER2 status, are also influenced by hereditary factors. To identify genetic variants associated with pathological characteristics of breast cancer patients, a Genome Wide Association Study was performed in a cohort of 9365 women from the French nationwide SIGNAL/PHARE studies (NCT00381901/RECF1098). Strong association between the FGFR2 locus and ER status of breast cancer patients was observed (ER-positive n=6211, ER-negative n=2516; rs3135718 OR=1...
October 14, 2016: Oncotarget
Anthony Ferrari, Anne Vincent-Salomon, Xavier Pivot, Anne-Sophie Sertier, Emilie Thomas, Laurie Tonon, Sandrine Boyault, Eskeatnaf Mulugeta, Isabelle Treilleux, Gaëtan MacGrogan, Laurent Arnould, Janice Kielbassa, Vincent Le Texier, Hélène Blanché, Jean-François Deleuze, Jocelyne Jacquemier, Marie-Christine Mathieu, Frédérique Penault-Llorca, Frédéric Bibeau, Odette Mariani, Cécile Mannina, Jean-Yves Pierga, Olivier Trédan, Thomas Bachelot, Hervé Bonnefoi, Gilles Romieu, Pierre Fumoleau, Suzette Delaloge, Maria Rios, Jean-Marc Ferrero, Carole Tarpin, Catherine Bouteille, Fabien Calvo, Ivo Glynne Gut, Marta Gut, Sancha Martin, Serena Nik-Zainal, Michael R Stratton, Iris Pauporté, Pierre Saintigny, Daniel Birnbaum, Alain Viari, Gilles Thomas
HER2-positive breast cancer has long proven to be a clinically distinct class of breast cancers for which several targeted therapies are now available. However, resistance to the treatment associated with specific gene expressions or mutations has been observed, revealing the underlying diversity of these cancers. Therefore, understanding the full extent of the HER2-positive disease heterogeneity still remains challenging. Here we carry out an in-depth genomic characterization of 64 HER2-positive breast tumour genomes that exhibit four subgroups, based on the expression data, with distinctive genomic features in terms of somatic mutations, copy-number changes or structural variations...
2016: Nature Communications
George Huntington
No abstract text is available yet for this article.
July 2016: British Journal of Psychiatry: the Journal of Mental Science
Maria Vaccarella
This article explores the often perplexing experience of being an epilepsy surgery candidate, as portrayed in four book-length accounts: Laura Doermer's Moritz mein Sohn (Moritz my son, 1990), David B.'s L'ascension du haut mal (The ascent of the high evil, 1996; published in English as Epileptic, 2003), Ray Robinson's Electricity (2006), and Alberto Capitta's Il giardino non esiste (The garden doesn't exist, 2009). Building upon critical disability studies and the work of French poststructuralists Gilles Deleuze and Félix Guattari, I analyze issues of embodiment, identity and narrative (re)construction in the postsurgical alleviation of chronic illness...
2015: Literature and Medicine
Mona Lilja, Mikael Baaz
This paper offers a new interpretation of the 'resistance' carried out by local civil society organisations in Cambodia against intimate partner violence (IPV). In this, the paper explores the nexus between 'rupture', 'resistance' and 'repetition' and concludes that different 'repetitions' can contribute to acts of violence while simultaneously creating possibilities for resisting IPV. In regard to the latter, the concept of 'rupture' is investigated as a performative politics through which organisations try to disrupt the 'repetitions' of violent masculinities...
2016: Global Public Health
Amit Prasad
Stem cell therapy in non-Western countries such as India has received a lot of attention. Apart from media reports, there are a number of social science analyses of stem cell policy, therapy, and research, their ethical implications, and impact of advertising on patients. Nevertheless, in the media reports as well as in academic studies, experiences of patients, who undertake overseas journeys for stem cell therapy, have largely been either ignored or presented reductively, often as a "false hope." In this article, I analyze the experiences of patients and their "journeys of hope" to NuTech Mediworld, an embryonic stem cell therapy clinic in New Delhi, India...
March 2015: Health (London)
Guilherme Gonzaga Duarte Providello, Silvio Yasui
After presenting the ideas on madness and its interface with art as expressed in the writings of Michel Foucault, Peter Pál Pelbart, and Gilles Deleuze, the article explores how these authors question the relationship between art and madness. It begins with the notion that madness does not tell the truth about art, and vice versa, but that there are links between both that must be delved into if we are to engage in deeper reflection on the topic. The text problematizes the statement that madness is the absence of an oeuvre and examines how this impacts the possibility of achieving an artistic oeuvre...
October 2013: História, Ciências, Saúde—Manguinhos
Cameron Duff
'Context' is one of the most enduring analytical devices in social science accounts of alcohol and other drug (AOD) use, although its elaboration tends to emphasise macro-structural processes (like economic change, law enforcement, health policy, racism or stigma) at the expense of more finely-grained understandings of the place and time of consumption. Drawing on Gilles Deleuze's notion of the assemblage, and its reception in recent critical geographies of AOD use, I will characterise context as an assemblage of social, affective and material forces...
May 2014: International Journal on Drug Policy
M Roberts
Reflections upon what it might mean to think, and about what inherited presuppositions or images might influence what thinking is thought to consist of, are not readily considered in the mental health care literature. However, the work of the 20th century French philosopher Gilles Deleuze and, in particular, his account of 'the dogmatic image of thought' can be employed to illustrate how such considerations can be of relevance to the theoretical and practical concerns of mental health professionals. In doing so, Deleuze's work can be understood as seeking to sensitize mental health professionals to the dangers of unreflectively adopting a restrictive notion of what it means to think, as well as an exhortation to develop critical, creative thinking in the mental health professions that moves beyond the bounds of the traditional, dogmatic image of thought...
May 2014: Journal of Psychiatric and Mental Health Nursing
Atte Oksanen
This theoretical article presents and applies the theories of the French philosopher Gilles Deleuze. The article takes as its starting point the observation that current biomedical, social and psychological research does not provide a coherent view of the nature of addiction and there is a great deal of controversy in the field. The material philosophy of Deleuze provides the opportunity to introduce new ideas and bridge the gaps between different theories and approaches. Deleuze's philosophy is especially useful since neurological research on addiction has developed rapidly...
January 2013: Journal of Psychoactive Drugs
Anne M Sochan
How should nursing knowledge advance? This exploration contextualizes its evolution past and present. In addressing how it evolved in the past, a probable historical evolution of its development draws on the perspectives of Frank & Gills's World System Theory, Kuhn's treatise on Scientific Revolutions, and Foucault's notions of Discontinuities in scientific knowledge development. By describing plausible scenarios of how nursing knowledge evolved, I create a case for why nursing knowledge developers should adopt a post-structural stance in prioritizing their research agenda(s)...
July 2011: Nursing Philosophy: An International Journal for Healthcare Professionals
Anne-Christine Merveille, Erica E Davis, Anita Becker-Heck, Marie Legendre, Israel Amirav, Géraldine Bataille, John Belmont, Nicole Beydon, Frédéric Billen, Annick Clément, Cécile Clercx, André Coste, Rachelle Crosbie, Jacques de Blic, Stephane Deleuze, Philippe Duquesnoy, Denise Escalier, Estelle Escudier, Manfred Fliegauf, Judith Horvath, Kent Hill, Mark Jorissen, Jocelyne Just, Andreas Kispert, Mark Lathrop, Niki Tomas Loges, June K Marthin, Yukihide Momozawa, Guy Montantin, Kim G Nielsen, Heike Olbrich, Jean-François Papon, Isabelle Rayet, Gilles Roger, Miriam Schmidts, Henrique Tenreiro, Jeffrey A Towbin, Diana Zelenika, Hanswalter Zentgraf, Michel Georges, Anne-Sophie Lequarré, Nicholas Katsanis, Heymut Omran, Serge Amselem
Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by recurrent infections of the upper and lower respiratory tract, reduced fertility in males and situs inversus in about 50% of affected individuals (Kartagener syndrome). It is caused by motility defects in the respiratory cilia that are responsible for airway clearance, the flagella that propel sperm cells and the nodal monocilia that determine left-right asymmetry. Recessive mutations that cause PCD have been identified in genes encoding components of the outer dynein arms, radial spokes and cytoplasmic pre-assembly factors of axonemal dyneins, but these mutations account for only about 50% of cases of PCD...
January 2011: Nature Genetics
Cameron Duff
This article explores the work of French thinker Gilles Deleuze and argues for the application of his central ideas to the study of health and human development. Deleuze's work furnishes a host of ontological and epistemological resources for such analysis, ushering in new methods and establishing new objects of inquiry. Of principal interest are the inventive conceptualizations of affect, multiplicity and relationality that Deleuze proposes, and the novel reading of subjectivity that these concepts support...
November 2010: Health (London)
M Roberts
The active involvement of those people who have at one time used, or who continue to use, mental health services has come to be seen as a central feature of both the policy and the practice of modern mental health care. However, while those people who use mental health services may face a variety of obstacles to active participation in their care and in the provision of mental health services more generally, this paper will draw on the work of Gilles Deleuze, arguably one of the most important philosophers of the late 20th century, to suggest that the language of psychiatry--and, in particular, the attendant valuations or 'sense' of psychiatry's diagnostic categories--serve to restrict the participation of people in their individual care and in the provision of mental health services...
May 2010: Journal of Psychiatric and Mental Health Nursing
Armin Schäfer
The article investigates literary subjectivity in some texts by Samuel Beckett. The article proceeds by relating the ways of how narration and speech acts constitute literary subjectivity to the problems of subjectivity that scientific investigations deal with. While successful self-regulation of the organism nourishes the roots of subjectivity, i.e., the habits, subjectivity decomposes in states of exhaustion, when self-regulation breaks down. As soon as a certain threshold is transgressed, fatigue sets in, alters the personality and eventually leads to exhaustion--a state, which psychiatrists compare to mental illness...
December 2009: Berichte Zur Wissenschaftsgeschichte
M Roberts
The concept of emotional intelligence is gaining increasing precedence in the nursing literature, with particular emphasis placed upon its importance for various aspects of the nursing profession and the demand for greater attention to be given to its development in the education of nurses. Accordingly, this paper will seek to contribute to this emerging body of research by proposing that the employment of poetry in the education of mental health nurses provides a valuable opportunity for the development of emotional intelligence and, in particular, the development of one of the central characteristics of emotional intelligence; namely, empathy...
April 2010: Journal of Psychiatric and Mental Health Nursing
Mauro Basaure
What psychiatry was for the anti-psychiatry movement, psychoanalysis was for the French 'Anti-Oedipus movement' represented by Robert Castel, Gilles Deleuze and Felix Guattari. Until now, the contribution of Foucault to this critical movement has been little known. In this paper I reconstruct in a systematic and exhaustive way Foucault's critique of psychoanalysis and, in particular, of the Oedipus-complex theory. I demonstrate that this critique presupposes a very specific epistemology and social theory. On an epistemological level, Foucault focuses on the power effects of psychoanalysis as a discourse of subjectivity...
September 2009: History of Psychiatry
John Winslade
The philosophical groundwork of Gilles Deleuze is examined for its relevance for narrative practice in therapy and conflict resolution. Deleuze builds particularly on Foucault's analytics of power as "actions upon actions" and represents power relations diagrammatically in terms of lines of power. He also conceptualizes lines of flight through which people become other. These concepts are explored in relation to a conversation with a couple about a crisis in their relationship. Tracing lines of power and lines of flight are promoted as fresh descriptions of professional practice that fit well with the goals of narrative practice...
September 2009: Family Process
Amy L Hequembourg
Lesbian mothering strategies are commonly theorized as instances of assimilationism or resistance. This essay critiques those approaches and presents a promising alternative using the conceptual framework of Gilles Deleuze and Felix Guattari. Their concepts of "becoming" and "rhizoming" are utilized as mechanisms for understanding the inconsistencies and contradictions that constitute the subjectivities of two lesbian co-mothers. The essay concludes with the political implications of these analyses.
2007: Journal of Homosexuality
Lucille Cairns
This paper shows how Anne Garréta's Pas un jour (2002) is a decidedly queer text, in both the new and the old sense of that contested epithet. I examine three interrelated concerns central to Pas un jour. First, I analyze Garréta's mediation of desire in general: her own experiences of it; modalities thereof which subvert more 'normative' models of lesbianism; and her convergences with other gay, but male writers and theorists of desire such as Guy Hocquenghem, Gilles Deleuze and Michel Foucault. Second, I interrogate Garréta's dichotomy between desire and friendship, and adumbrate contrasts with Foucauldian theory...
2007: Journal of Lesbian Studies
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