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Enhancement of appetite supressant

Alan R Mackie, Hameed Rafiee, Paul Malcolm, Louise Salt, George van Aken
The aim of this study was to determine the extent to which gastric layering and retention of a meal could be used to reduce appetite using the same caloric load. Liquid (control) and semi-solid (active) meals were produced with the same protein, fat, carbohydrate, and mass. These were fed to 10 volunteers on separate days in a crossover study, and subjective appetite ratings, gastric contents, and plasma cholecystokinin (CCK) were assessed over a period of 3 h. The active meal showed food boluses in the stomach persisting for ~45 min, slower emptying rates, and lower plasma CCK levels over the first hour...
June 1, 2013: American Journal of Physiology. Gastrointestinal and Liver Physiology
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