Xue Gu, Xiaoli Li, Xue Zhang, Li Tong, Ran Feng, Lei Liu, Hui Sun, Qing Zhang, Tingting Bian, Jianguo Zhang, Lihua Gao, Chenxi Zhang, Jian Liu, Yifei Liu
BACKGROUND: There is growing evidence showing that 6-phosphofructo-2-kinase (PFKFB3) plays crucial roles in different types of human cancers, including LUAD; however, the specific mechanism by which PFKFB3 plays a role in LUAD remains unclear. METHODS: We investigated the expression of PFKFB3 and explored the underlying mechanism as well as the correlation with immune markers using several online datasets, such as Tumor Immune Estimate Resource (TIMER), UALCAN, and the Cancer Genome Atlas (TCGA) databases, miRWalk, Targetscan, MiRDB and starBase database...
2023: OncoTargets and Therapy