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https://www.readbyqxmd.com/read/29046728/high-prevalence-of-berardinelli-seip-congenital-lipodystrophy-in-rio-grande-do-norte-state-northeast-brazil
#1
Lázaro Batista de Azevedo Medeiros, Verônica Kristina Cândido Dantas, Aquiles Sales Craveiro Sarmento, Lucymara Fassarella Agnez-Lima, Adriana Lúcia Meireles, Thaiza Teixeira Xavier Nobre, Josivan Gomes de Lima, Julliane Tamara Araújo de Melo Campos
BACKGROUND: Berardinelli-Seip Congenital Lipodystrophy (BSCL) is a rare disease characterized by the almost complete absence of adipose tissue. Although a large number of BSCL cases was previously identified in Rio Grande do Norte (RN), a state in Northeast Brazil, its prevalence in RN regions and municipalities remains unknown. The purpose of this study was to better characterize the prevalence of BSCL in RN. METHODS: A descriptive study was conducted using secondary data obtained from the Association of Parents and People with BSCL of RN to determine its prevalence...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29017474/the-disease-burden-of-suicide-in-ecuador-a-15%C3%A2-years-geodemographic-cross-sectional-study-2001-2015
#2
Esteban Ortiz-Prado, Katherine Simbaña, Lenin Gómez, Aquiles R Henriquez-Trujillo, Fernando Cornejo-Leon, Eduardo Vasconez, Diana Castillo, Ginés Viscor
BACKGROUND: Suicide affects people from different backgrounds, ethnical groups, socio-economic status and geographical locations. In Latin America, suicide reports arescarce, specially in Andean countries. In Ecuador, very few reports have partially described this phenomenon, nonetheless, estimation of the burden of disease (BoD) hasnever been reported in the country. METHODS: A country-wide comparison was performed using the Ministry of Public Health's national databases of overall mortality, Hospital Discharges Database, and the Population Census of the National Institute of Census and Statistics (INEC)...
October 10, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28884585/analysis-of-the-cost-effectiveness-of-carbetocin-for-the-prevention-of-hemorrhage-following-cesarean-delivery-in-ecuador
#3
Aquiles Rodrigo Henríquez-Trujillo, Ruth Alicia Lucio-Romero, Kerlly Bermúdez-Gallegos
AIM: To compare the cost of carbetocin with that of oxytocin for the prevention and management of hemorrhage following cesarean delivery in Ecuador. MATERIALS & METHODS: We developed a decision tree based cost-effectiveness model to compare carbetocin with oxytocin in the prevention of hemorrhage following cesarean delivery in Ecuador. Our model was run from a third party payer perspective and was validated by local experts in the field. The efficacy of the interventions was determined based on a systematic review of the literature...
September 8, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/28867577/biological-properties-of-cardiac-mesenchymal-stem-cells-in-rats-with-diabetic-cardiomyopathy
#4
Diógenes Rodrigo Maronezzi de Paula, Vanessa Capuano, Daniel Mendes Filho, Anna Cecília Dias Maciel Carneiro, Virgínia de Oliveira Crema, Lucas Felipe de Oliveira, Aldo Rogélis Aquiles Rodrigues, Nicola Montano, Valdo José Dias da Silva
Cardiomyopathy is a major outcome in patients with diabetes mellitus (DM) and contributes to the high morbidity/mortality observed in this disease. AIMS: To evaluate several biological properties of cardiac mesenchymal stem cells (cMSCs) in a rat model of streptozotocin-induced DM with concomitant diabetic cardiomyopathy. MAIN METHODS: After 10weeks of DM induction, diabetic and control rats were assessed using ECG and ventricular hemodynamics monitoring. Then, the hearts were excised and processed for histology and for extracting non-cardiomyocytic cells...
November 1, 2017: Life Sciences
https://www.readbyqxmd.com/read/28752317/shifting-the-set-of-stimulus-selection-when-switching-between-tasks
#5
Mike Wendt, Aquiles Luna-Rodriguez, Thomas Jacobsen
Switching between tasks associated with different requirements of stimulus selection may suffer interference from persisting attentional settings or processes of reconfiguration, possibly constituting a source of task switch costs (i.e., impaired performance in task switch trials compared to task repetition trials). To explore the processes involved in task switching with and without a switch in stimulus selection requirements, we administered a task-switching paradigm that involved task-unique sets of hierarchical (Navon) stimuli, preventing stimulus-related proactive interference (i...
July 27, 2017: Psychological Research
https://www.readbyqxmd.com/read/28742013/first-canadian-experience-with-donation-after-cardiac-death-simultaneous-pancreas-and-kidney-transplants
#6
Patrick T Anderson, Shahid Aquil, Kelly McLean, Vivian C McAlister, Alp Sener, Patrick P Luke
BACKGROUND: Compared with neurologic determination of death (NDD) donor organs, donation after cardiac death (DCD) donor organs have traditionally been considered of inferior quality owing to warm ischemia experienced during procurement. We present, to our knowledge, the first analysis of simultaneous pancreas and kidney (SPK) transplants using DCD donor organs in Canada. METHODS: We carried out a retrospective cohort study of SPK transplants from 13 DCD and 68 NDD donors performed between October 2008 and July 2016...
September 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28627450/impact-of-fixation-artifacts-and-threshold-selection-on-high-resolution-melting-analysis-for-kras-mutation-screening
#7
Wendy Pérez-Báez, Ethel A García-Latorre, Héctor Aquiles Maldonado-Martínez, Iris Coronado-Martínez, Leonardo Flores-García, Lucía Taja-Chayeb
INTRODUCTION: Treatment in metastatic colorectal cancer (mCRC) has expanded with monoclonal antibodies targeting epidermal growth factor receptor, but is restricted to patients with a wild-type (WT) KRAS mutational status. The most sensitive assays for KRAS mutation detection in formalin-fixed paraffin embedded (FFPE) tissues are based on real-time PCR. Among them, high resolution melting analysis (HRMA), is a simple, fast, highly sensitive, specific and cost-effective method, proposed as adjunct for KRAS mutation detection...
October 2017: Molecular and Cellular Probes
https://www.readbyqxmd.com/read/28536543/adoption-of-task-specific-sets-of-visual-attention
#8
Mike Wendt, Svantje T Kähler, Aquiles Luna-Rodriguez, Thomas Jacobsen
Evidence from behavioral and physiological studies suggests attentional weighting of stimulus information from different sources, according to task demands. We investigated the adoption of task-specific attentional sets by administering a flanker task, which required responding to a centrally presented letter while ignoring two adjacent letters, and a same-different judgment task, which required a homogenous/heterogeneous classification concerning the complete three-letter string. To assess the distribution of attentional weights across the letter locations we intermixed trials of a visual search task, in which a target stimulus occurred randomly in any of these locations...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28484204/hydrogen-sulfide-improves-cardiomyocyte-function-in-a-cardiac-arrest-model
#9
Nahuel Aquiles Garcia, Javier Moncayo-Arlandi, Alejandro Vazquez, Patricia Genovés, Conrado J Calvo, José Millet, Nuria Martí, Carmen Aguado, Erwin Knecht, Iñigo Valiente-Alandi, José A Montero, Antonio Díez-Juan, Pilar Sepúlveda
BACKGROUND Cardioplegic arrest is a common procedure for many types of cardiac surgery, and different formulations have been proposed to enhance its cardio-protective effect. Hydrogen sulfide is an important signaling molecule that has cardio-protective properties. We therefore studied the cardio-protective effect of hydrogen sulfide in cardiac cell culture and its potential therapeutic use in combination with cardioplegia formulations. MATERIAL AND METHODS We added hydrogen sulfide donor GYY4137 to HL-1 cells to study its protective effect in nutrient starved conditions...
May 9, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28456306/characterization-and-establishment-of-a-reference-deltamethrin-and-cypermethrin-resistant-tick-line-ivri-iv-of-rhipicephalus-boophilus-microplus
#10
Srikant Ghosh, Snehil Gupta, K G Ajith Kumar, Anil Kumar Sharma, Sachin Kumar, Gaurav Nagar, Rinesh Kumar, Souvik Paul, Ashutosh Fular, Gajanan Chigure, Abhijit Nandi, H V Manjunathachar, Aquil Mohammad, M R Verma, B C Saravanan, Debdatta Ray
The problem of ticks and tick borne diseases is a global threat and growing reports of resistance to commonly used insecticides further aggravated the condition and demands for country specific resistance monitoring tools and possible solutions of the problem. Establishment of standard reference is prerequisite for development of monitoring tools. For studying possible role of different mechanisms involved in development of resistance in Rhipicephalus (Boophilus) microplus population and to develop newer drug to manage the problem of resistance, a deltamethrin exposed and selected tick colony, referred to as IVRI-IV, was characterized using reference susceptible IVRI-I tick line as control...
May 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/28368156/-strategic-control-over-extent-and-timing-of-distractor-based-response-activation-correction-to-jost-et-al-2017
#11
(no author information available yet)
Reports an error in "Strategic control over extent and timing of distractor-based response activation" by Kerstin Jost, Mike Wendt, Aquiles Luna-Rodriguez, Andreas Löw and Thomas Jacobsen (Journal of Experimental Psychology: Learning, Memory, and Cognition, 2017[Feb], Vol 43[2], 326-333). In the article, the images to Figures 2 and 3 were switched during production. The online version of this article has been corrected. (The following abstract of the original article appeared in record 2016-48458-001.) In choice reaction time (RT) tasks, performance is often influenced by the presence of nominally irrelevant stimuli, referred to as distractors...
April 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28356978/reproducibility-of-the-egfr-immunohistochemistry-scores-for-tumor-samples-from-patients-with-advanced-non-small-cell-lung-cancer
#12
Alejandro Avilés-Salas, Saé Muñiz-Hernández, Héctor Aquiles Maldonado-Martínez, José G Chanona-Vilchis, Laura-Alejandra Ramírez-Tirado, Norma HernáNdez-Pedro, Rita Dorantes-Heredia, José Manuel RuíZ-Morales, Daniel Motola-Kuba, Oscar Arrieta
Epidermal growth factor receptor (EGFR) is overexpressed in >60% of non-small cell lung cancer (NSCLC) cases. In combination with radiotherapy or chemotherapy, first-line treatments with antibodies against EGFR, including cetuximab and necitumumab, have demonstrated benefits by increasing overall survival (OS), particularly in patients who overexpress EGFR. The present study evaluated the interobserver agreement among three senior pathologists, who were blinded to the clinical outcomes and assessed tumor samples from 85 patients with NSCLC using the H-score method...
February 2017: Oncology Letters
https://www.readbyqxmd.com/read/28190980/effect-of-low-dose-short-term-creatine-supplementation-on-muscle-power-output-in-elite-youth-soccer-players
#13
Aquiles Yáñez-Silva, Cosme F Buzzachera, Ivan Da C Piçarro, Renata S B Januario, Luis H B Ferreira, Steven R McAnulty, Alan C Utter, Tacito P Souza-Junior
BACKGROUND: To determine the effects of a low dose, short-term Creatine monohydrate (Cr) supplementation (0.03 g.kg.d(-1) during 14 d) on muscle power output in elite youth soccer players. METHODS: Using a two-group matched, double blind, placebo-controlled design, nineteen male soccer players (mean age = 17.0 ± 0.5 years) were randomly assigned to either Cr (N = 9) or placebo (N = 10) group. Before and after supplementation, participants performed a 30s Wingate Anaerobic Test (WAnT) to assess peak power output (PPO), mean power output (MPO), fatigue index (FI), and total work...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28018922/influence-of-the-expression-of-inflammatory-markers-on-kidney-after-fetal-programming-in-an-experimental-model-of-renal-failure
#14
Carlos Donizete Pereira Júnior, Camila Souza de Oliveira Guimarães, Aline Cristina Souza da Silva, Aldo Rogelis Aquiles Rodrigues, Maria Aparecida da Glória, Vicente de Paula Antunes Teixeira, Niels Olsen Saraiva Câmara, Lenaldo Branco Rocha, Marlene Antônia Dos Reis, Juliana Reis Machado, Laura Penna Rocha, Fernanda Rodrigues Helmo, Rosana Rosa Miranda Corrêa
Objective. To evaluate the expression of inflammatory markers in experimental renal failure after fetal programming. Methods. The offspring aged two and five months were divided into four groups: CC (control dams, control offspring); DC (diabetic dams, control offspring); CFA (control dams, folic acid offspring, 250 mg/Kg); and DFA (diabetic dams, folic acid offspring). Gene expression of inflammatory markers MCP-1, IL-1, NOS3, TGF-β, TNF-α, and VEGF was evaluated by RT-PCR. Results. MCP-1 was increased in the CFA and DFA groups at two and five months of age, as well as in DC5 when compared to CC5...
2016: Journal of Immunology Research
https://www.readbyqxmd.com/read/27973071/epidemiological-profiling-of-chronic-headache-patients-at-a-public-tertiary-care-setting-in-india
#15
A K Najmi, M U Hoda, S Hussain, A Habib, P Kapur, A Anwar, M Akhtar, M Aquil
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27926850/background-suppression-in-imaging-gold-nanorods-through-detection-of-anti-stokes-emission
#16
Aquiles Carattino, Veer I P Keizer, Marcel J M Schaaf, Michel Orrit
Metallic nanoparticles have opened the possibility of imaging, tracking, and manipulating biological samples without time limitations. Their low photoluminescence quantum yield, however, makes them hard to detect under high background conditions. In this study we show that it is possible to image gold nanorods by detecting their anti-Stokes emission under resonant excitation. We show that even in the membrane of a cell containing the fluorescent dye Atto 647N, the signal/background of the anti-Stokes emission can be >10, while it is impossible to image the particles with the Stokes emission...
December 6, 2016: Biophysical Journal
https://www.readbyqxmd.com/read/27832230/inflammatory-and-immunological-profiles-in-patients-with-copd-relationship-with-fev-1-reversibility
#17
Cleriston Farias Queiroz, Antonio Carlos Moreira Lemos, Maria de Lourdes Santana Bastos, Margarida Célia Lima Costa Neves, Aquiles Assunção Camelier, Natália Barbosa Carvalho, Edgar Marcelino de Carvalho
Objective: To determine whether COPD severity correlates with sputum cell counts, atopy, and asthma. Methods: This was a cross-sectional study involving 37 patients with COPD and 22 healthy subjects with normal lung function (controls). Sputum cell counts were determined by microscopy after centrifugation of samples. Skin prick tests were performed, and serum cytokines were determined by ELISA. Results: Patients were stratified by bronchodilator response: a non-reversible airflow limitation (nonRAL) group comprised 24 patients showing no significant post-bronchodilator change in FEV1; and a partially reversible airflow limitation (partialRAL) group comprised 13 patients showing FEV1 reversibility (post-bronchodilator FEV1 increase ≥ 12%)...
July 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/27816203/-relationship-between-balance-tests-and-mobility-scale-fear-of-falling-and-the-number-of-falls-in-the-elderly-in-a-rehabilitation-department
#18
LETTER
Haviley Oliveira Martins, Karoline Mayara de Aquiles Bernardo, Maristela Santini Martins, Fábio Marcon Alfieri
No abstract text is available yet for this article.
July 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/27741241/noninvasive-diagnosis-of-visceral-leishmaniasis-development-and-evaluation-of-two-urine-based-immunoassays-for-detection-of-leishmania-donovani-infection-in-india
#19
Sarfaraz Ahmad Ejazi, Pradyot Bhattacharya, Md Asjad Karim Bakhteyar, Aquil Ahmad Mumtaz, Krishna Pandey, Vidya Nand Ravi Das, Pradeep Das, Mehebubar Rahaman, Rama Prosad Goswami, Nahid Ali
BACKGROUND: Visceral Leishmaniasis (VL), a severe parasitic disease, could be fatal if diagnosis and treatment is delayed. Post kala-azar dermal leishmaniasis (PKDL), a skin related outcome, is a potential reservoir for the spread of VL. Diagnostic tests available for VL such as tissue aspiration are invasive and painful although they are capable of evaluating the treatment response. Serological tests although less invasive than tissue aspiration are incompetent to assess cure. Parasitological examination of slit-skin smear along with the clinical symptoms is routinely used for diagnosis of PKDL...
October 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27732019/strategic-control-over-extent-and-timing-of-distractor-based-response-activation
#20
Kerstin Jost, Mike Wendt, Aquiles Luna-Rodriguez, Andreas Löw, Thomas Jacobsen
In choice reaction time (RT) tasks, performance is often influenced by the presence of nominally irrelevant stimuli, referred to as distractors. Recent research provided evidence that distractor processing can be adjusted to the utility of the distractors: Distractors predictive of the upcoming target/response were more attended to and also elicited stronger motor responses. In an event-related potential (ERP) study, we investigated whether not only the extent of distractor processing (as suggested by these previous results), but also the timing of distractor-based response activation is subject to strategic control...
October 10, 2016: Journal of Experimental Psychology. Learning, Memory, and Cognition
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