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https://www.readbyqxmd.com/read/29715314/the-burden-of-acute-respiratory-infections-in-ecuador-2011-2015
#1
Wilson Chicaiza-Ayala, Aquiles R Henríquez-Trujillo, Esteban Ortiz-Prado, Richard W Douce, Marco Coral-Almeida
BACKGROUND: Burden of disease studies intend to improve public health decision-making and to measure social and economic impact in population. The objective of this study was to describe the burden of acute respiratory infections (ARI) in Ecuador between 2011 and 2015. METHODS: Five-year period morbidity and mortality data available from national agencies of statistics was analyzed to estimate the burden of disease attributable to acute respiratory infections. Cases and deaths registered were grouped according to their ICD-10 code into three diagnostic groups: Acute upper respiratory infections (J00-J06), Influenza and pneumonia (J09-J18), and Bronchitis and other acute lower respiratory infections (J20-J22, J85, J86)...
2018: PloS One
https://www.readbyqxmd.com/read/29704856/fast-mapping-word-meanings-across-trials-young-children-forget-all-but-their-first-guess
#2
Athulya Aravind, Jill de Villiers, Amy Pace, Hannah Valentine, Roberta Golinkoff, Kathy Hirsch-Pasek, Aquiles Iglesias, Mary Sweig Wilson
Do children learn a new word by tracking co-occurrences between words and referents across multiple instances ("cross-situational learning" models), or is word-learning a "one-track" process, where learners maintain a single hypothesis about the possible referent, which may be verified or falsified in future occurrences ("propose-but-verify" models)? Using a novel word-learning task, we ask which learning procedure is utilized by preschool-aged children. We report on findings from three studies comparing the word-learning strategies across different populations of child learners: monolingual English learners, Spanish - English dual language learners, and learners at risk for language-delay...
April 25, 2018: Cognition
https://www.readbyqxmd.com/read/29701245/a-morphological-database-for-606-colombian-bird-species
#3
Paola Montoya, Mailyn A Gonzalez, Elkin A Tenorio, Juan Pablo López-Ordóñez, Alejandro Pinto Gómez, Diego Cueva, Aldemar A Acevedo Rincón, Camilo Angarita Yanes, Héctor Manuel Arango Martínez, Orlando Armesto, Jefry S Betancur, Angela Caguazango Castro, Jhon Jairo Calderon Leyton, Edna Viviana Calpa-Anaguano, Ghislaine Cárdenas-Posada, Michael Castaño Díaz, Sergio Chaparro-Herrera, Nicolás Diago-Muñoz, Laura Franco Espinosa, Luis Germán Gómez Bernal, Fanny L Gonzalez-Zapata, Eduardo Aquiles Gutiérrez Zamora, Ana M Gutiérrez-Zuluaga, Robinson Stivel Lizcano Jiménez, Andrea Lopera-Salazar, Dariel Martínez Alvarado, Ana María Maya Girón, Wilderson Medina, Carolina Montealegre-Talero, Juan L Parra, Sebastián Pérez-Peña, Francis Ramírez Ramírez, Julián Reyes, Héctor Fabio Rivera-Gutiérrez, Yuri Rosero Mora, Carlos M Trujillo-Torres, Cristian Camilo Vidal-Maldonado, Beatriz Salgado-Negret
Colombia is the country with the highest bird diversity in the world. Despite active research in ornithology, compelling morphological information of most bird species is still sparse. However, morphological information is the baseline to understand how species respond to environmental variation and how ecosystems respond to species loss. As part of a national initiative, the Instituto Alexander von Humboldt in collaboration with twelve Colombian institutions and seven biological collections, measured up to 15 morphological traits of 9892 individuals corresponding to 606 species: 3492 from individuals captured in field and 6400 from museum specimens...
April 27, 2018: Ecology
https://www.readbyqxmd.com/read/29682202/ctcf-kdm4a-complex-correlates-with-histone-modifications-that-negatively-regulate-chd5-gene-expression-in-cancer-cell-lines
#4
Lissania Guerra-Calderas, Rodrigo González-Barrios, Carlos César Patiño, Nicolás Alcaraz, Marisol Salgado-Albarrán, David Cantú de León, Clementina Castro Hernández, Yesennia Sánchez-Pérez, Héctor Aquiles Maldonado-Martínez, Inti A De la Rosa-Velazquez, Fernanda Vargas-Romero, Luis A Herrera, Alejandro García-Carrancá, Ernesto Soto-Reyes
Histone demethylase KDM4A is involved in H3K9me3 and H3K36me3 demethylation, which are epigenetic modifications associated with gene silencing and RNA Polymerase II elongation, respectively. KDM4A is abnormally expressed in cancer, affecting the expression of multiple targets, such as the CHD5 gene. This enzyme localizes at the first intron of CHD5 , and the dissociation of KDM4A increases gene expression. In vitro assays showed that KDM4A-mediated demethylation is enhanced in the presence of CTCF, suggesting that CTCF could increase its enzymatic activity in vivo, however the specific mechanism by which CTCF and KDM4A might be involved in the CHD5 gene repression is poorly understood...
March 30, 2018: Oncotarget
https://www.readbyqxmd.com/read/29649337/leg-length-skull-circumference-and-the-incidence-of-dementia-in-latin-america-and-china-a-10-66-population-based-cohort-study
#5
Martin J Prince, Daisy Acosta, Mariella Guerra, Yueqin Huang, Ivonne Z Jimenez-Velazquez, Juan J Llibre Rodriguez, Aquiles Salas, Ana Luisa Sosa, Michael E Dewey, Maelenn M Guerchet, Zhaorui Liu, Jorge J Llibre Guerra, A Matthew Prina
BACKGROUND: Adult leg length is influenced by nutrition in the first few years of life. Adult head circumference is an indicator of brain growth. Cross-sectional studies indicate inverse associations with dementia risk, but there have been few prospective studies. METHODS: Population-based cohort studies in urban sites in Cuba, Dominican Republic Puerto Rico and Venezuela, and rural and urban sites in Peru, Mexico and China. Sociodemographic and risk factor questionnaires were administered to all participants, and anthropometric measures taken, with ascertainment of incident dementia, and mortality, three to five years later...
2018: PloS One
https://www.readbyqxmd.com/read/29568522/association-of-sleep-quality-with-excessive-daytime-somnolence-and-quality-of-life-of-elderlies-of-community
#6
Glauber Sá Brandão, Fernanda Warken Rosa Camelier, Antônia Adonis Callou Sampaio, Glaudson Sá Brandão, Anderson Soares Silva, Glaucia Sá Brandão Freitas Gomes, Claudio F Donner, Luis Vicente Franco Oliveira, Aquiles Assunção Camelier
Background: The progressive increase in the elderly population contributes to the fact that studies on human aging have important attention of health professionals and government agents, since they present a great challenge regarding public health. Our objective is to characterize the profile of older people with poor sleep quality and analyze possible associations with excessive daytime somnolence, quality of life and functional mobility. Methods: This is a cross-sectional descriptive study, involving elderlies of the community, with the questionnaires Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, WHOQOL-OLD and application of the Timed Up and Go test - TUG...
2018: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29489847/reproductive-period-endogenous-estrogen-exposure-and-dementia-incidence-among-women-in-latin-america-and-china-a-10-66-population-based-cohort-study
#7
Martin J Prince, Daisy Acosta, Mariella Guerra, Yueqin Huang, Ivonne Z Jimenez-Velazquez, Juan J Llibre Rodriguez, Aquiles Salas, Ana Luisa Sosa, Kia-Chong Chua, Michael E Dewey, Zhaorui Liu, Rosie Mayston, Adolfo Valhuerdi
BACKGROUND: Exposure to endogenous estrogen may protect against dementia, but evidence remains equivocal. Such effects may be assessed more precisely in settings where exogenous estrogen administration is rare. We aimed to determine whether reproductive period (menarche to menopause), and other indicators of endogenous estrogen exposure are inversely associated with dementia incidence. METHODS: Population-based cohort studies of women aged 65 years and over in urban sites in Cuba, Dominican Republic, Puerto Rico and Venezuela, and rural and urban sites in Peru, Mexico and China...
2018: PloS One
https://www.readbyqxmd.com/read/29372056/home-exercise-improves-the-quality-of-sleep-and-daytime-sleepiness-of-elderlies-a-randomized-controlled-trial
#8
Glauber Sá Brandão, Glaucia Sá Brandão Freitas Gomes, Glaudson Sá Brandão, Antônia A Callou Sampaio, Claudio F Donner, Luis V F Oliveira, Aquiles Assunção Camelier
Background: Aging causes physiological changes which affect the quality of sleep. Supervised physical exercise is an important therapeutic resource to improve the sleep of the elderlies, however there is a low adherence to those type of programs, so it is necessary to implement an exercise program which is feasible and effective. The study aimed to test the hypothesis that a semi-supervised home exercise program, improves sleep quality and daytime sleepiness of elderlies of the community who present poor sleep quality...
2018: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29365005/recommendations-for-the-pharmacological-treatment-of-copd-questions-and-answers
#9
Frederico Leon Arrabal Fernandes, Alberto Cukier, Aquiles Assunção Camelier, Carlos Cezar Fritscher, Cláudia Henrique da Costa, Eanes Delgado Barros Pereira, Irma Godoy, José Eduardo Delfini Cançado, José Gustavo Romaldini, Jose Miguel Chatkin, José Roberto Jardim, Marcelo Fouad Rabahi, Maria Cecília Nieves Maiorano de Nucci, Maria da Penha Uchoa Sales, Maria Vera Cruz de Oliveira Castellano, Miguel Abidon Aidé, Paulo José Zimermann Teixeira, Renato Maciel, Ricardo de Amorim Corrêa, Roberto Stirbulov, Rodrigo Abensur Athanazio, Rodrigo Russo, Suzana Tanni Minamoto, Fernando Luiz Cavalcanti Lundgren
The treatment of COPD has become increasingly effective. Measures that range from behavioral changes, reduction in exposure to risk factors, education about the disease and its course, rehabilitation, oxygen therapy, management of comorbidities, and surgical and pharmacological treatments to end-of-life care allow health professionals to provide a personalized and effective therapy. The pharmacological treatment of COPD is one of the cornerstones of COPD management, and there have been many advances in this area in recent years...
July 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29306607/the-prevalence-and-correlates-of-frailty-in-urban-and-rural-populations-in-latin-america-china-and-india-a-10-66-population-based-survey
#10
Juan J Llibre Rodriguez, A Matthew Prina, Daisy Acosta, Mariella Guerra, Yueqin Huang, K S Jacob, Ivonne Z Jimenez-Velasquez, Aquiles Salas, Ana Luisa Sosa, Joseph D Williams, A T Jotheeswaran, Isaac Acosta, Zhaorui Liu, Martin J Prince
BACKGROUND: There have been few cross-national studies of the prevalence of the frailty phenotype conducted among low or middle income countries. We aimed to study the variation in prevalence and correlates of frailty in rural and urban sites in Latin America, India, and China. METHODS: Cross-sectional population-based catchment area surveys conducted in 8 urban and 4 rural catchment areas in 8 countries; Cuba, Dominican Republic, Puerto Rico, Venezuela, Peru, Mexico, China, and India...
April 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29046728/high-prevalence-of-berardinelli-seip-congenital-lipodystrophy-in-rio-grande-do-norte-state-northeast-brazil
#11
Lázaro Batista de Azevedo Medeiros, Verônica Kristina Cândido Dantas, Aquiles Sales Craveiro Sarmento, Lucymara Fassarella Agnez-Lima, Adriana Lúcia Meireles, Thaiza Teixeira Xavier Nobre, Josivan Gomes de Lima, Julliane Tamara Araújo de Melo Campos
BACKGROUND: Berardinelli-Seip Congenital Lipodystrophy (BSCL) is a rare disease characterized by the almost complete absence of adipose tissue. Although a large number of BSCL cases was previously identified in Rio Grande do Norte (RN), a state in Northeast Brazil, its prevalence in RN regions and municipalities remains unknown. The purpose of this study was to better characterize the prevalence of BSCL in RN. METHODS: A descriptive study was conducted using secondary data obtained from the Association of Parents and People with BSCL of RN to determine its prevalence...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29017474/the-disease-burden-of-suicide-in-ecuador-a-15-years-geodemographic-cross-sectional-study-2001-2015
#12
Esteban Ortiz-Prado, Katherine Simbaña, Lenin Gómez, Aquiles R Henriquez-Trujillo, Fernando Cornejo-Leon, Eduardo Vasconez, Diana Castillo, Ginés Viscor
BACKGROUND: Suicide affects people from different backgrounds, ethnical groups, socio-economic status and geographical locations. In Latin America, suicide reports arescarce, specially in Andean countries. In Ecuador, very few reports have partially described this phenomenon, nonetheless, estimation of the burden of disease (BoD) hasnever been reported in the country. METHODS: A country-wide comparison was performed using the Ministry of Public Health's national databases of overall mortality, Hospital Discharges Database, and the Population Census of the National Institute of Census and Statistics (INEC)...
October 10, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28884585/analysis-of-the-cost-effectiveness-of-carbetocin-for-the-prevention-of-hemorrhage-following-cesarean-delivery-in-ecuador
#13
Aquiles Rodrigo Henríquez-Trujillo, Ruth Alicia Lucio-Romero, Kerlly Bermúdez-Gallegos
AIM: To compare the cost of carbetocin with that of oxytocin for the prevention and management of hemorrhage following cesarean delivery in Ecuador. MATERIALS & METHODS: We developed a decision tree based cost-effectiveness model to compare carbetocin with oxytocin in the prevention of hemorrhage following cesarean delivery in Ecuador. Our model was run from a third party payer perspective and was validated by local experts in the field. The efficacy of the interventions was determined based on a systematic review of the literature...
September 8, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/28867577/biological-properties-of-cardiac-mesenchymal-stem-cells-in-rats-with-diabetic-cardiomyopathy
#14
Diógenes Rodrigo Maronezzi de Paula, Vanessa Capuano, Daniel Mendes Filho, Anna Cecília Dias Maciel Carneiro, Virgínia de Oliveira Crema, Lucas Felipe de Oliveira, Aldo Rogélis Aquiles Rodrigues, Nicola Montano, Valdo José Dias da Silva
Cardiomyopathy is a major outcome in patients with diabetes mellitus (DM) and contributes to the high morbidity/mortality observed in this disease. AIMS: To evaluate several biological properties of cardiac mesenchymal stem cells (cMSCs) in a rat model of streptozotocin-induced DM with concomitant diabetic cardiomyopathy. MAIN METHODS: After 10weeks of DM induction, diabetic and control rats were assessed using ECG and ventricular hemodynamics monitoring. Then, the hearts were excised and processed for histology and for extracting non-cardiomyocytic cells...
November 1, 2017: Life Sciences
https://www.readbyqxmd.com/read/28752317/shifting-the-set-of-stimulus-selection-when-switching-between-tasks
#15
Mike Wendt, Aquiles Luna-Rodriguez, Thomas Jacobsen
Switching between tasks associated with different requirements of stimulus selection may suffer interference from persisting attentional settings or processes of reconfiguration, possibly constituting a source of task switch costs (i.e., impaired performance in task switch trials compared to task repetition trials). To explore the processes involved in task switching with and without a switch in stimulus selection requirements, we administered a task-switching paradigm that involved task-unique sets of hierarchical (Navon) stimuli, preventing stimulus-related proactive interference (i...
January 2018: Psychological Research
https://www.readbyqxmd.com/read/28742013/first-canadian-experience-with-donation-after-cardiac-death-simultaneous-pancreas-and-kidney-transplants
#16
Patrick T Anderson, Shahid Aquil, Kelly McLean, Vivian C McAlister, Alp Sener, Patrick P Luke
BACKGROUND: Compared with neurologic determination of death (NDD) donor organs, donation after cardiac death (DCD) donor organs have traditionally been considered of inferior quality owing to warm ischemia experienced during procurement. We present, to our knowledge, the first analysis of simultaneous pancreas and kidney (SPK) transplants using DCD donor organs in Canada. METHODS: We carried out a retrospective cohort study of SPK transplants from 13 DCD and 68 NDD donors performed between October 2008 and July 2016...
September 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28627450/impact-of-fixation-artifacts-and-threshold-selection-on-high-resolution-melting-analysis-for-kras-mutation-screening
#17
Wendy Pérez-Báez, Ethel A García-Latorre, Héctor Aquiles Maldonado-Martínez, Iris Coronado-Martínez, Leonardo Flores-García, Lucía Taja-Chayeb
INTRODUCTION: Treatment in metastatic colorectal cancer (mCRC) has expanded with monoclonal antibodies targeting epidermal growth factor receptor, but is restricted to patients with a wild-type (WT) KRAS mutational status. The most sensitive assays for KRAS mutation detection in formalin-fixed paraffin embedded (FFPE) tissues are based on real-time PCR. Among them, high resolution melting analysis (HRMA), is a simple, fast, highly sensitive, specific and cost-effective method, proposed as adjunct for KRAS mutation detection...
October 2017: Molecular and Cellular Probes
https://www.readbyqxmd.com/read/28536543/adoption-of-task-specific-sets-of-visual-attention
#18
Mike Wendt, Svantje T Kähler, Aquiles Luna-Rodriguez, Thomas Jacobsen
Evidence from behavioral and physiological studies suggests attentional weighting of stimulus information from different sources, according to task demands. We investigated the adoption of task-specific attentional sets by administering a flanker task, which required responding to a centrally presented letter while ignoring two adjacent letters, and a same-different judgment task, which required a homogenous/heterogeneous classification concerning the complete three-letter string. To assess the distribution of attentional weights across the letter locations we intermixed trials of a visual search task, in which a target stimulus occurred randomly in any of these locations...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28484204/hydrogen-sulfide-improves-cardiomyocyte-function-in-a-cardiac-arrest-model
#19
Nahuel Aquiles Garcia, Javier Moncayo-Arlandi, Alejandro Vazquez, Patricia Genovés, Conrado J Calvo, José Millet, Nuria Martí, Carmen Aguado, Erwin Knecht, Iñigo Valiente-Alandi, José A Montero, Antonio Díez-Juan, Pilar Sepúlveda
BACKGROUND Cardioplegic arrest is a common procedure for many types of cardiac surgery, and different formulations have been proposed to enhance its cardio-protective effect. Hydrogen sulfide is an important signaling molecule that has cardio-protective properties. We therefore studied the cardio-protective effect of hydrogen sulfide in cardiac cell culture and its potential therapeutic use in combination with cardioplegia formulations. MATERIAL AND METHODS We added hydrogen sulfide donor GYY4137 to HL-1 cells to study its protective effect in nutrient starved conditions...
May 9, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28456306/characterization-and-establishment-of-a-reference-deltamethrin-and-cypermethrin-resistant-tick-line-ivri-iv-of-rhipicephalus-boophilus-microplus
#20
Srikant Ghosh, Snehil Gupta, K G Ajith Kumar, Anil Kumar Sharma, Sachin Kumar, Gaurav Nagar, Rinesh Kumar, Souvik Paul, Ashutosh Fular, Gajanan Chigure, Abhijit Nandi, H V Manjunathachar, Aquil Mohammad, M R Verma, B C Saravanan, Debdatta Ray
The problem of ticks and tick borne diseases is a global threat and growing reports of resistance to commonly used insecticides further aggravated the condition and demands for country specific resistance monitoring tools and possible solutions of the problem. Establishment of standard reference is prerequisite for development of monitoring tools. For studying possible role of different mechanisms involved in development of resistance in Rhipicephalus (Boophilus) microplus population and to develop newer drug to manage the problem of resistance, a deltamethrin exposed and selected tick colony, referred to as IVRI-IV, was characterized using reference susceptible IVRI-I tick line as control...
May 2017: Pesticide Biochemistry and Physiology
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